PKD1L2 (NM_052892) Human Untagged Clone

CAT#: SC305688

PKD1L2 (untagged)-Human polycystic kidney disease 1-like 2 (PKD1L2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PKD1L2
• Synonyms: PC1L2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_052892, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGTGCAGTGGGCTTGGTACTCCTGGTGCTTGCTCTGAGGCTTAGGGCCACCACTGTTAAGCCAGAGG
  AAGGCAGCTTTTGCTCTAACAGCCAGGTGGCCTTCAGAGATGCTTGCTATGAATTTGTGCCACTCGGACG
  CACCTTCCGTGATGCCCAGAGCTGGTGCGAGGGGCAAGGAGGCCATTTGGTCTTCATTCAGGACGAAGGC
  ACCCAGTGGTTTCTGCAGAAGCACATCTCCCAGGACAGGGAATGGTGGATTGGACTCACGTGGAACTTGG
  CACGGAATGGAACCACGGAGGGGCCGGGGACTTGGTTGGACACCTCCAATGTGACCTACAGCAACTGGCA
  TGGAGGGCAGGCCGCCGCTGCCCCTGACACCTGCGGCCACATCGGGAGAGGCCCTTCCTCTGAGTGGGTG
  ACCTCGGACTGCGCCCAGACCTTCGCCTTCATGTGCGAGTTCCGGGTTGGCCAGAGCCTGGCCTGCGAGG
  GACTCAATGCCACCGTGCACTGTGGCTTGGGGCAGGTCATCCAGGTCCAGGATGCCGTCTACGGGCGCCA
  GAATCCCCATTTCTGCACCCAGGATGCCGGGCGTCCTTCAGATCTGGAGCAGGGATGCAGCTGGGCCAAC
  GTCAAGGAGGAGGTGGCAGGCCAGTGCCAGGAGCTACAGTCATGCCAGGTGGCAGCAGATGAGACCTACT
  TTGGAAACCTGTGTCCGACTCAGGGCAGTTACCTGTGGGTGCAGTACCAGTGCCGGGAAGCCCTGCAGCT
  GATGGTGTCCAGTGAGAGTTTCATCTTTGACAATGTCACCATCTCCCTGACGTGGCTCCTCTCACCCTAC
  ATAGGAAACCTGTCCTGTATAATTAGTACAGGAGACAGCCACACTTTTGATCCCTACAACCCGCCGAGTG
  TGTCCAGCAATGTGACCCACCAGTTCACATCTCCTGGGGAATTCACCGTGTTTGCTGAATGCACAACCAG
  TGAGTGGCATGTGACAGCTCAGAGGCAGGTGACCGTGCGAGACAAGATGGAGACGCTCAGTGTGACTGCA
  TGCTCCGGCCTGTCCCAGTCAGGAGCCGGCCCTCTCTGCCAGGCTGTCTTTGGGGATCCTCTGTGGATTC
  AGGTGGAGCTTGATGGAGGAACAGGAGTGACTTACACTGTGCTTTTGGGTGACATAACCCTGGCCGAGTC
  CACCACCCAAAAGGGCTCGCTACCGTACAATCTGATCCTGGACAGAGAAACCCAGAAACTGATGGGCCCT
  GGGAGGCACCGCCTGGAGATCCAAGCCACCGGCAACACCACCACCTCTACAATCTCCAGAAACATTACAG
  TCCACTTGGTGGAGCTGCTGTCAGGGCTGCAGGCCTCCTGGGCTTCTGACCATTTGGAGCTTGGACAGGA
  CCTATTGATCACCATCTCATTGGCTCAGGGCACCCCGGAAGAGCTGACCTTTGAGGTGGCTGGACTCAAT
  GCAACCTTCTCCCACGAGCAAGTGAGCTTTGGAGAGCCATTTGGGATTTGCCGCCTGGCTGTTCCGGTTG
  AAGGCACCTTTCTGGTCACCATGCTGGTGAGGAATGCCTTCTCCAACCTGAGTTTGGAAATCGGGAACAT
  CACTATCACAGCCCCTTCCGGTCTCCAAGAACCATCTGGGATGAATGCTGAAGGAAAGAGTAAAGATAAA
  GGCGATATGGAGGTGTACATCCAACCTGGTCCATATGTGGATCCTTTCACGACAGTGACCCTGGGCTGGC
  CAGACAATGACAAGGAGTTACGCTTCCAATGGTCATGTGGGTCTTGCTGGGCTCTGTGGAGCAGCTGTGT
  TGAGAGGCAGCTGCTTCGCACAGACCAGAGGGAGCTGGTGGTTCCAGCATCCTGCCTGCCGCCGCCTGAC
  TCTGCTGTCACCCTGCGCCTGGCTGTTCTGAGAGGCCAAGAGCTGGAGAACAGGGCAGAGCAGTGCCTCT
  ACGTGTCTGCGCCCTGGGAACTCAGGCCTCGAGTCAGCTGTGAGAGGAACTGCAGGCCAGTTAATGCCAG
  CAAAGACATTCTGCTCAGGGTCACCATGGGGGAGGACTCTCCAGTGGCTATGTTCAGCTGGTATTTGGAC
  AACACCCCAACAGAGCAGGCTGAGCCCCTCCTGGATGCCTGCAGACTCAGAGGATTTTGGCCAAGGTCCT
  TAACCCTCCTCCAGAGCAACACCTCCACGTTGCTGTTGAACAGCTCGTTTCTGCAGTCCCGGGGAGAGGT
  CATCCGAATCAGAGCCACAGCACTGACCAGGCATGCCTATGGGGAGGACACCTATGTGATCAGCACTGTG
  CCTCCCCGTGAGGTGCCTGCCTGCACTATTGCCCCAGAGGAGGGCACCGTTCTGACGAGCTTTGCCATCT
  TCTGCAACGCCTCCACAGCCCTGGGACCCCTGGAGTTCTGCTTCTGTCTGGAATCAGGTTCCTGCCTACA
  CTGTGGCCCTGAACCTGCCCTCCCATCAGTGTATCTGCCACTTGGAGAGGAGAACAATGACTTTGTGCTG
  ACAGTAGTTATTTCTGCCACCAATCGTGCAGGGGACACGCAGCAGACCCAGGCCATGGCTAAGGTGGCAC
  TCGGAGACACATGTGTTGAGGATGTAGCATTCCAGGCTGCCGTGTCAGAGAAAATCCCCACAGCTCTGCA
  AGGCGAGGGTGGCCCCGAGCAGCTCCTCCAGCTGGCCAAGGCTGTGTCCTCCATGCTGAACCAAGAGCAT
  GAAAGCCAGGGCTCAGGACAGTCACTGAGCATAGACGTCAGACAGAAGGTCAGAGAGCATGTGCTGGGAT
  CACTGTCTGCAGTCACCACCGGCTTGGAGGACGTGCAGAGGGTGCAGGAGCTGGCCGAGGTGCTGAGAGA
  GGTGACCTGCCGGAGTAAGGAACTCACACCCTCGGCCCAGTGGGAGGCCAGCTTGGCTCTACAGCATGCC
  AGTGAGGCCCTGTTGACAGTGAGTGCCAAGGCCCGCCCTGAGGACCAGAGGCGCCAGGCAGCCACCAGGG
  ACCTGTTTCAGGCTGTGGGCAGTGTGCTGGAAGCTTCCCTGAGCAACAGACCAGAAGAGCCTGCGGAGGC
  CAGCAGCAGCCAGATTGCCACAGTGCTGCGGCTGCTTCGAGTCATGGAGCATGTGCAGACCACCCTCCTG
  CTGGGAAAACTGCCAGGGGGCCTTCCAGCCATGCTGGCCACCCCCTCCATCTCTGTGTACACAAACAGAA
  TACAACCCTGGAGTTGGCAAGGCTCCTCCCTGCGCCCTGATGCCGCAGACTCTGCAACCTTCATGCTGCC
  CGCTGCCTCCTCCCTCAGCTCTCTGGAGGGCGGCCAGGAGCCCGTGGATATAAAGATCATGAGTTTCCCA
  AAGAGCCCCTTTCCAGCCCGAAGCCACTTTGATGTCAGCGGGACTGTCGGTGGCCTCCGTGTGACCAGCC
  CTAGTGGTCAACTCATACCTGTGAAGAATCTGTCGGAGAATATCGAGATCCTGCTGCCCCGGCATTCACA
  AAGACACAGCCAGCCGACCGTGTTGAACCTGACCAGTCCTGAAGCTTTGTGGGTGAACGTGACTTCAGGG
  GAGGCAACCTTGGGGATCCAGCTGCACTGGAGACCAGACATTGCACTCACGCTTAGCCTGGGCTATGGCT
  ACCACCCCAACAAGAGCAGCTACGATGCCCAAACTCACCTCGTACCAATGGTGGCTCCAGATGAGCTGCC
  CACGTGGATCCTGAGCCCACAGGACCTGCGTTTTGGAGAAGGGGTCTACTATTTGACTGTGGTCCCTGAG
  TCTGACCTGGAGCCAGCCCCCGGCAGGGACCTCACGGTTGGCATCACCACCTTCCTGTCTCACTGTGTGT
  TCTGGGATGAGGTCCAGGAGACTTGGGACGACTCAGGATGCCAGGTGGGGCCTCGGACCAGCCCCTACCA
  GACACACTGCCTCTGCAACCACCTCACTTTCTTCGGAAGCACGTTCCTGGTGATGTCCAATGCCATCAAC
  ATCCACCAGACTGCTGAGCTCTTTGCCACCTTTGAGGACAACCCTGTGGTCGTGACCACCGTGGGCTGCC
  TGTGTGTGGTCTACGTGCTGGTGGTGATCTGGGCGAGGAGGAAGGACGCTCAGGATCAGGCCAAGGTGAA
  GGTCACAGTGCTGGAAGACAATGATCCCTTTGCTCAGTACCACTACCTGGTGACAGTCTACACAGGACAC
  CGACGAGGGGCAGCCACGTCCTCAAAGGTGACTGTCACCCTGTATGGCCTGGATGGAGAGAGAGAGCCCC
  ACCACCTGGCTGATCCCGACACTCCGGTTTTTGAGCGAGGAGCAGTGGATGCCTTCCTCCTCTCCACCCT
  GTTCCCCCTGGGAGAACTGCGGAGCCTCCGGCTGTGGCATGACAACTCAGGGGACCGGCCATCGTGGTAT
  GTGAGCCGGGTGCTGGTCTATGACCTGGTGATGGACCGGAAGTGGTATTTCCTGTGCAACTCCTGGCTAT
  CCATCAATGTTGGAGATTGCGTCCTCGATAAGGTGTTTCCTGTGGCCACGGAGCAGGACAGAAAACAATT
  CAGCCACCTGTTTTTCATGAAGACTTCCGCGGGCTTCCAGGATGGACACATCTGGTATTCGATCTTCAGC
  CGCTGCGCTCGCAGCAGCTTCACCCGCGTCCAGAGGGTGTCCTGCTGCTTCTCCCTGCTGCTGTGCACCA
  TGCTGACCAGCATCATGTTCTGGGGGGTCCCCAAGGACCCAGCTGAGCAAAAGATGGACTTGGGTAAAAT
  TGAATTCACCTGGCAGGAGGTGATGATTGGCCTGGAGAGCTCCATCCTCATGTTCCCCATCAACCTCCTG
  ATTGTTCAGATCTTTCAGAACACCCGTCCCCGGGTCGCGAAGGAGCAGAACACTGGAAAATGGGACCGGG
  GGTCCCCCAACCTGACTCCCTCCCCACAGCCCATGGAGGACGGCCTTCTGACACCTGAGGCAGTGACCAA
  GGATGTGTCAAGAATCGTCAGCTCCCTCTTCAAAGCTCTCAAGGTGCCATCCCCCGCCTTGGGCTGGGAC
  TCAGTGAACTTGATGGACATCAACAGTCTCCTCGCCTTGGTGGAAGATGTCATTTATCCACAGAACACAT
  CAGGGCAGGTGTTCTGGGAGGAAGCCAAAAAGAGAGAGGACCCTGTAACACTCACTTTGGGGTCATCAGA
  AATGAAAGAGAAATCACAGTGTCCCAAGCCCAAGGCGGCACGGAGTGGCCCCTGGAAGGACAGCGCCTAC
  AGGCAGTGTCTGTACCTTCAGCTGGAACACGTGGAGCAAGAGCTGCGGCTGGTGGGGCCCCGAGGCTTCT
  CCCAGCCCCACAGCCATGCCCAGGCCCTCAGGCAGCTGCAGACCCTGAAGGGCGGCCTGGGGGTACAGCC
  GGGCACCTGGGCCCCTGCACATGCCAGCGCTCTTCAGGTGAGCAAACCCCCTCAAGGCCTGCCCTGGTGG
  TGCATCCTGGTGGGCTGGCTCCTGGTAGCGGCCACCAGTGGCGTGGCGGCCTTCTTCACCATGCTCTACG
  GCCTGCACTACGGGAGGGCCAGCTCCCTCAGGTGGCTCATCTCCATGGCTGTCTCCTTCGTGGAGAGCAT
  GTTCGTCACCCAGCCCCTGAAGGTGCTGGGATTCGCTGCTTTCTTTGCACTGGTCTTGAAGAGAGTGGAC
  GATGAGGAGGATACTGTGGCCCCGCTGCCAGGACATCTGTTGGGCCCAGACCCCTATGCCTTGTTCCGAG
  CACGAAGAAACAGCAGCAGGGATGTCTACCAGCCACCTCTCACCGCTGCCATTGAGAAGATGAAAACCAC
  CCACCTCAAGGAACAGAAAGCATTTGCCCTCATCAGAGAAATCCTGGCATACTTGGGCTTCCTGTGGATG
  CTACTGCTCGTGGCCTACGGGCAGAGGGACCCCAGCGCCTACCACCTCAACAGACACCTCCAGCACAGCT
  TCACCAGGGGCTTTTCAGGTGTGCTCGGCTTCCGAGAGTTCTTCAAGTGGGCCAACACCACCCTCGTGAG
  TAACCTGTATGGTCACCCCCCAGGCTTTATCACTGATGGGAACTCCAAGCTGGTTGGCAGTGCCCAGATT
  CGTCAAGTGAGGGTCCAGGAAAGCTCTTGCCCTCTTGCCCAGCAGCCGCAGGCATATCTCAACGGATGCC
  GTGCACCATATTCCCTGGATGCTGAAGACATGGCAGACTATGGGGAAGGCTGGAATGCCACCACCCTCAG
  TGAATGGCAGTACCAGAGCCAGGACCAACGTCAAGGGTATCCCATCTGGGGCAAACTCACTGTGTACCGG
  GGAGGAGGCTACGTGGTCCCCTTGGGGACTGATCGCCAAAGCACGTCAAGAATTCTCCGCTATCTCTTTG
  ACAACACCTGGCTGGACGCCCTGACCAGAGCTGTGTTTGTGGAGTCCACTGTCTACAACGCCAACGTCAA
  CCTGTTCTGCATTGTCACGCTGACGCTAGAGACCAGCGCTCTGGGCACCTTTTTTACGCACGCGGCCCTG
  CAGAGCCTCCGCCTGTACCCCTTCACCGACGGCTGGCACCCCTTCGTGGTAGCGGCAGAGCTCATCTACT
  TCCTCTTCCTCCTCTACTACATGGTGGTGCAGGGCAAGCGCATGAGTAAAGAGACGTGGGGCTATTTCTG
  CAGCAAGTGGAACCTTCTGGAGCTGGCCATCATCCTGGCCAGCTGGAGCGCCCTGGCGGTGTTTGTGAAG
  AGGGCTGTCCTGGCCGAAAGGGACCTCCAGCGCTGCCGGAACCACAGGGAGGAAGGCATCAGCTTCAGTG
  AGACAGCAGCAGCCGATGCCGCCCTTGGCTACATCATTGCCTTCCTGGTACTCCTGTCCACAGTGAAGCT
  TTGGCATCTGCTCAGGTTGAATCCCAAAATGAACATGATCACGGCAGCCCTACGCCGTGCCTGGGGCGAC
  ATTTCAGGCTTTATGATTGTCATCCTTACCATGCTCCTGGCTTACTCCATCGCGTCAAACTTGATATTTG
  GTTGGAAACTCCGTTCCTACAAAACCCTCTTTGATGCGGCGGAGACGATGGTCAGCCTTCAGCTGGGAAT
  CTTCAACTACGAGGAGGTCCTGGACTATAGCCCAGTGCTTGGCTCCTTCCTCATTGGATCCTGCATTGTT
  TTTATGACATTTGTGGTGCTGAACCTGTTTATCTCTGTCATCCTGGTGGCCTTCAGTGAGGAGCAAAAAT
  ACTATCAGCTGTCGGAGGAAGGGGAGATCGTAGATTTGCTGCTGATGAAAATACTCAGTTTCCTGGGCAT
  TAAGTCTAAGAGAGAGGAGCCTGGAAGCAGCAGGGAGCAGCCTGGGTCTCTGTCCCAGACTCGCCACTCT
  CGACCAGCACAAGCTTTGCCCAAGGACTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_052892
• ORF Size: 7380 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_052892.3, NP_443124.3
• RefSeq Size: 7624
• RefSeq ORF: 7380
• Locus ID: 114780
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, and the reference genome encodes a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2019]
  Transcript Variant: This variant (1, also known as long form) represents the functional allele that is absent from the reference genome but present in some human individuals. This variant is the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.