NPFFR2 (NM_053036) Human Untagged Clone

CAT#: SC305717

NPFFR2 (untagged)-Human neuropeptide FF receptor 2 (NPFFR2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NPFFR2
• Synonyms: GPR74; HLWAR77; NPFF2; NPGPR
• Vector: pCMV6-AC-Myc-DDK
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_053036, the custom clone sequence may differ by one or more nucleotides
  ATGAATGAGAAATGGGACACAAACTCTTCAGAAAACTGGCATCCCATCTGGAATGTCAAT
  GACACAAAGCATCATCTGTACTCAGATATTAATATTACCTATGTGAACTACTATCTTCAC
  CAGCCTCAAGTGGCAGCAATCTTCATTATTTCCTACTTTCTGATCTTCTTTTTGTGCATG
  ATGGGAAATACTGTGGTTTGCTTTATTGTAATGAGGAACAAACATATGCACACAGTCACT
  AATCTCTTCATCTTAAACCTGGCCATAAGTGATTTACTAGTTGGCATATTCTGCATGCCT
  ATAACACTGCTGGACAATATTATAGCAGGATGGCCATTTGGAAACACGATGTGCAAGATC
  AGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTGCT
  GTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCG
  TTTGTCATTATTATGATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTA
  ATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAACC
  AGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACC
  ACTGTGCTGTTTGCCAACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGA
  AGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGGAG
  CAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCC
  CTGCTTTTTATTCTCTCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCT
  GACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACTGG
  CTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTC
  CGCCGTGGTTTCCAAGAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATG
  GAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTGTC
  CAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAA
  AAACCCCAACAGGAATTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATT
  TAA
  
• Restriction Sites: Please inquire
• ACCN: NM_053036
• ORF Size: 1263 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_053036.1, NP_444264.1
• RefSeq Size: 1560
• RefSeq ORF: 1263
• Locus ID: 10886
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR that causes translation initiation at a downstream AUG, and results an isoform (2) with a shorter N-terminus compared to isoform 1.