GAB3 (NM_080612) Human Untagged Clone

CAT#: SC305803

GAB3 (untagged)-Human GRB2-associated binding protein 3 (GAB3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GAB3
• Synonyms: DOS; Gab3 protein; Gab3 scaffolding protein; Gab family member 3; GRB2-associated binding protein 3; OTTHUMP00000026055
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_080612, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGTGCGGGCGACGCAGTGTGCACCGGCTGGCTCGTTAAGTCGCCCCCCGAGAGGAAGCTACAGCGCT
  ACGCCTGGCGCAAGCGCTGGTTTGTCCTCCGGCGAGGCCGCATGAGCGGCAACCCCGATGTCTTGGAGTA
  CTACAGGAACAAGCACTCCAGCAAGCCCATCCGGGTGATAGACCTCAGCGAGTGTGCAGTGTGGAAGCAT
  GTGGGCCCCAGCTTTGTTCGGAAGGAATTTCAGAATAATTTCGTGTTCATTGTCAAGACTACTTCCCGTA
  CATTCTACCTGGTGGCCAAAACTGAGCAAGAAATGCAGGTGTGGGTGCACAGCATCAGTCAGGTCTGCAA
  CCTTGGCCACCTGGAGGATGGTGCAGATTCCATGGAGAGCCTCTCTTACACGCCCTCCTCCCTGCAGCCA
  TCCTCTGCCAGCTCCCTTCTTACCGCCCATGCTGCCAGCTCCTCTTTGCCAAGAGATGACCCAAACACTA
  ATGCCGTAGCCACTGAGGAAACCAGAAGTGAGTCAGAGCTTCTCTTCCTTCCAGATTATCTGGTTTTGTC
  CAACTGCGAGACTGGAAGACTGCACCATACCAGTCTACCCACCAGATGTGATAGCTGGTCAAACTCAGAC
  CGTTCATTGGAACAGGCTTCATTTGATGATGTTTTTGTTGACTGCCTGCAGCCGCTCCCCTCCAGTCATT
  TGGTCCACCCCTCATGCCATGGCAGTGGAGCTCAGGAGGTGCCATCCTCGAGGCCTCAGGCTGCCCTGAT
  CTGGAGTAGAGAAATCAATGGGCCACCCAGGGACCACTTGTCTTCTTCACCATTGCTGGAAAGTTCCTTA
  AGTTCCACCATTCAGGTAGATAAAAATCAAGGTTCCTTACCCTGTGGAGCAAAAGAACTAGACATTATGT
  CCAACACTCCACCTCCCCGCCCCCCTAAGCCAAGCCATCTGTCTGAACGGCGCCAAGAGGAGTGGAGTAC
  ACACAGTGGTAGCAAGAAGCCAGAATGCACTCTGGTTCCAAGAAGAATCTCCCTCTCTGGTTTAGACAAC
  ATGAGAACCTGGAAAGCTGATGTAGAAGGCCAATCCTTAAGACACCGAGACAAGCGGCTTAGTTTGAATT
  TGCCATGCAGGTTCTCCCCGATGTACCCCACAGCTTCAGCCAGTATCGAAGACAGCTATGTGCCCATGAG
  CCCCCAGGCTGGTGCCTCTGGTCTTGGACCCCACTGCAGCCCTGATGACTACATTCCAATGAACTCAGGA
  AGCATCTCAAGCCCGTTGCCTGAGCTGCCTGCAAACCTGGAACCTCCCCCAGTGAATAGAGATCTCAAGC
  CTCAGAGGAAATCACGGCCACCTCCTCTGGACCTGAGAAACCTCTCGATCATCCGGGAACATGCATCTCT
  TACCAGGACCCGCACTGTGCCTTGCAGTCGAACCAGCTTTCTCTCTCCAGAAAGAAATGGTATTAATTCT
  GCAAGATTTTTTGCTAATCCTGTTTCCAGAGAAGACGAAGAAAGCTACATCGAAATGGAGGAGCACCGAA
  CAGCCAGTTCCCTGAGCAGTGGTGCCCTTACGTGGACAAAGAAATTCAGCCTAGATTATTTGGCCCTGGA
  CTTCAATTCAGCATCACCAGCCCCCATGCAGCAGAAACTTCTCCTTTCAGAAGAACAAAGAGTAGACTAT
  GTCCAAGTGGATGAGCAGAAGACACAGGCTCTCCAGAGCACAAAACAGGAGTGGACGGATGAAAGGCAAT
  CCAAAGTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_080612
• ORF Size: 1761 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_080612.3, NP_542179.1
• RefSeq Size: 4761
• RefSeq ORF: 1761
• Locus ID: 139716
• Gene Summary: This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.