HE4 (WFDC2) (NM_080734) Human Untagged Clone

CAT#: SC305822

WFDC2 (untagged)-Human WAP four-disulfide core domain 2 (WFDC2), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WFDC2
• Synonyms: HE4, WAP5, MGC57529, dJ461P17.6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_080734 edited
  ATGCCTGCTTGTCGCCTAGGCCCGCTAGCCGCCGCCCTCCTCCTCAGCCTGCTGCTGTTC
  GGCTTCACCCTAGTCTCAGATAAGGAGGGTTCCTGCCCCCAGGTGAACATTAACTTTCCC
  CAGCTCGGCCTCTGTCGGGACCAGTGCCAGGTGGACAGCCAGTGTCCTGGCCAGATGAAA
  TGCTGCCGCAATGGCTGTGGGAAGGTGTCCTGTGTCACTCCCAATTTCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_080734 unedited
  CCGCCGTTGAGCAATGGGCGGTAGGCGCGCATAGAGGGAGGTCTATATAAGCAGAGCTCG
  TTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCA
  CGAGCACACCTGCACCCCGCCCGGGCATAGCACCATGCCTGCTTGTCGCCTAGGCCCGCT
  AGCCGCCGCCCTCCTCCTCAGCCTGCTGCTGTTCGGCTTCACCCTAGTCTCAGATAAGGA
  GGGTTCCTGCCCCCAGGTGAACATTAACTTTCCCCAGCTCGGCCTCTGTCGGGACCAGTG
  CCAGGTGGACAGCCAGTGTCCTGGCCAGATGAAATGCTGCCGCAATGGCTGTGGGAAGGT
  GTCCTGTGTCACTCCCAATTTCTGAGCTCCAGCCACCACCAGGCTGAGCAGTGAGGAGAG
  AAAGTTTCTGCCTGGCCCTGCATCTGGTTCCAGCCCACCTGCCCTCCCCTTTTTCGGGAC
  TCTGTATTCCCTCTTGGGCTGACCACAGCTTCTCCCTTTCCCAACCAATAAAGTAACCAC
  TTTCAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAAAGACAAAAAAAA
  AAAAAAAAAAAAGAGATAGCCAGAGAGAGAGAGGAGAGAGAAATAAAAAAACCCCTCCCC
  CCTTTATTTGGGGCGCCCGGGGTATAATTTTTTTTCCAGAAAAAAATCCCGGGGGGGGCC
  CCCTGGGACCCCCCCCCCGGGGCCCTTTCCGGGGCCCGGGAATTGGCCCCCCCGGGGCCC
  CCCCCCCTTGGGCCAAAAAAAAAAAAATTTGCCCTCATTTTGCCGAAAAAGGTGCCCCTT
  TAAAAAATATTAGGGTAAAAAGTTTTTTTTTTGACACAGGGGGCAAATTTGGAAAAACAC
  CCCGTGGGGGCGCGCGGGGGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_080734
• ORF Size: 231 bp
• Insert Size: 520
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_080734.1, NP_542772.1
• RefSeq Size: 421
• RefSeq ORF: 231
• Locus ID: 10406
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) lacks a fragment within the coding region, as compared to variant 1. Its reading frame is not impacted by the absence of the fragment, and it thus encodes a smaller protein which has identical N- and C-terminus to those of isoform 1 and contains only one WFDC domain.