OSCAR (NM_133169) Human Untagged Clone

CAT#: SC305929

OSCAR (untagged)-Human osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OSCAR
• Synonyms: PIgR-3; PIGR3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_133169 edited
  CACCATGGCCCTGGTGCTGATCCTCCAGCTGCTGACCCTCTGGCCTCTGTGTCACACAGA
  CATCACTCCGTCTGTCCCCCCAGCTTCATACCACCCTAAGCCATGGCTGGGAGCTCAGCC
  GGCTACAGTTGTGACCCCTGGGGTCAACGTGACCTTGAGATGCCGGGCACCCCAACCCGC
  TTGGAGATTTGGACTTTTCAAGCCTGGAGAGATCGCTCCCCTTCTCTTCCGGGATGTGTC
  CTCCGAGCTGGCAGAATTCTTTCTGGAGGAGGTGACTCCAGCCCAAGGGGGAAGTTACCG
  CTGCTGCTACCGAAGGCCAGACTGGGGGCCGGGTGTCTGGTCCCAGCCCAGCGATGTCCT
  GGAGCTGCTGGTGACAGAGGAGCTGCCGCGGCCGTCGCTGGTGGCGCTGCCCGGGCCGGT
  GGTGGGTCCTGGCGCCAACGTGAGCCTGCGCTGCGCGGGCCGCCTGCGGAACATGAGCTT
  CGTGCTGTACCGCGAGGGCGTGGCGGCCCCGCTGCAGTACCGCCACTCCGCGCAGCCCTG
  GGCCGACTTCACGCTGCTGGGCGCCCGCGCCCCCGGCACCTACAGCTGCTACTATCACAC
  GCCCTCCGCGCCCTACGTGCTGTCGCAGCGCAGCGAGGTGCTGGTCATCAGCTGGGAAGA
  CTCTGGCTCCTCCGACTACACCCGGGGGAACCTAGTCCGCCTGGGGCTGGCCGGGCTGGT
  CCTCATCTCCCTGGGCGCGCTGGTCACTTTTGACTGGCGCAGTCAGAACCGCGCTCCTGC
  TGGTATCCGCCCCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133169 unedited
  GGCAAAAAACATTCGCACCATGGCCCTGGTGCTGATCCTCCAGCTGCTGACCCTCTGGCC
  TCTGTGTCACACAGACATCACTCCGTCTGTCCCCCCAGCTTCATACCACCCTAAGCCATG
  GCTGGGAGCTCAGCCGGCTACAGTTGTGACCCCTGGGGTCAACGTGACCTTGAGATGCCG
  GGCACCCCAACCCGCTTGGAGATTTGGACTTTTCAAGCCTGGAGAGATCGCTCCCCTTCT
  CTTCCGGGATGTGTCCTCCGAGCTGGCAGAATTCTTTCTGGAGGAGGTGACTCCAGCCCA
  AGGGGGAAGTTACCGCTGCTGCTACCGAAGGCCAGACTGGGGGCCGGGTGTCTGGTCCCA
  GCCCAGCGATGTCCTGGAGCTGCTGGTGACAGAGGAGCTGCCGCGGCCGTCGCTGGTGGC
  GCTGCCCGGGCCGGTGGTGGGTCCTGGCGCCAACGTGAGCCTGCGCTGCGCGGGCCGCCT
  GCGGAACATGAGCTTCGTGCTGTACCGCGAGGGCGTGGCGGCCCCGCTGCAGTACCGCCA
  CTCCGCGCAGCCCTGGGCCGACTTCACGCTGCTGGGCGCCCGCGCCCCCGGCACCTACAG
  CTGCTACTATCACACGCCCTCCGCGCCCTACGTGCTGTCGCAGCGCAGCGAGGTGCTGGT
  CATCAGCTGGGAAGACTCTGGCTCCTCCGACTACACCCGGGGGGAACCTAGTCCGCCTGG
  GGCTGGCCCGGGCCTGTCCTCATCTCCCTGGGCGCGCTGGTCACTTTTGACTGGCGCAGT
  CAGAACCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133169 unedited
  NNNCCCGACCATTGGNNGATGGCACTTNCCAGGNCCAGNANGAGCACTGGGGNAGGGTCA
  CAGGGATGCCACCCGGGATCTGTTCAGGAAAAGCTATGACCGCGGCCGCAATCTATTNAG
  GGGCGGATACCAGCAGGAGCGCGGTTCTGACTGCGCCAGTCAAAAGTGACCAGCGCGCCC
  AGGGAGATGAGGACCAGCCCGGCCAGCCCCAGGCGGACTAGGTTCCCCCGGGTGTAGTCG
  GAGGAGCCAGAGTCTTCCCAGCTGATGACCAGCACCTCGCTGCGCTGCGACAGCACGTAG
  GGCGCGGAGGGCGTGTGATAGTAGCAGCTGTAGGTGCCGGGGGCGCGGGCGCCCAGCAGC
  GTGAAGTCGGCCCAGGGCTGCGCGGAGTGGCGGTACTGCAGCGGGGCCGCCACGCCCTCG
  CGGTACAGCACGAAGCTCATGTTCCGCAGGCGGCCCGCGCAGCGCAGGCTCACGTTGGCG
  CCAGGACCCACCACCGGCCCGGGCAGCGCCACCAGCGACGGCCGCGGCAGCTCCTCTGTC
  ACCAGCAGCTCCAGGACATCGCTGGGCTGGGACCAGACACCCGGCCCCCAGTCTGGCCTT
  CGGTAGCAGCAGCGGTAACTTCCCCCTTGGGCTGGAGTCACCTCCTCCAGAAAGAATTCT
  GCCAGCTCGGAGGACACATCCCGGAAGAGAGGGGAGCGATCTCTCCAGGCTTGAAAAGTC
  CAAATCTCCAAGCGGGTTGGGGTGCCCGGCATCTCAGGTCACGTTGACCCCAGGGGTCAC
  AACTGTAGCCGGCTGAGCTCCCAGCCATGGCTTAAGGTGGTATGAAAAGCTGGGGGACAG
  ACGAGTGATGTCTGTGTGACACAGAAGCCAGAGGGTCAGCAGCTGGAGGA
  
• Restriction Sites: Please inquire
• ACCN: NM_133169
• ORF Size: 792 bp
• Insert Size: 800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_133169.2, NP_573399.1
• RefSeq Size: 1428
• RefSeq ORF: 792
• Locus ID: 126014
• Protein Families: Druggable Genome
• Gene Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (4) lacks an in-frame exon in the central coding region and lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.