PGC1 beta (PPARGC1B) (NM_133263) Human Untagged Clone

CAT#: SC305937

PPARGC1B (untagged)-Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPARGC1B
• Synonyms: ERRL1; PERC; PGC-1(beta); PGC1B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_133263 edited
  CCACCTGGCTGCCTGCGCTTTACCCCTTGCTGAGGGCTGCGTGAGCTGGTCGCGGCGCCA
  GACACGGCGCAGGAAAGTGGGTGAGCGACCCCCGGCTCCCGCGGGCGCCGCGCGGCCCCG
  CCCCCGCAGCTAGCGGCCCTGCGGCAGCCGGGGGCTCGAGCTCCGCCCTCCGCCTCCCGC
  CGGCCTCACTCCCTCCTCCCTCCTCCCTTGCTCGCTCGCTGGCTCCCTCCCCCCGGGCCG
  GCTCGGCGTTGACTCCGCCGCACGCTGCAGCCGCGGCTGGAAGATGGCGGGGAACGACTG
  CGGCGCGCTGCTGGACGAAGAGCTCTCCTCCTTCTTCCTCAACTATCTCGCTGACACGCA
  GGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCCCA
  GCTGGATGCCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAGCTGCAGTGGTGCCCAGA
  GAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATTGA
  CAGTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAAGA
  TGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTGGAGACGCTCTATCATGCACCTC
  AGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCCCC
  AGCCCCTGAGGTGGACGAGCTCTCACTGCTGCAGAAGCTCCTCCTGGCCACATCCTACCC
  AACATCAAGCTCTGACACCCAGAAGGAAGGGACCGCCTGGCGCCAGGCAGGCCTCAGATC
  TAAAAGTCAACGGCCTTGTGTTAAGGCGGACAGCACCCAAGACAAGAAGGCTCCCATGAT
  GCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCACCTCGGCACAGTGCTG
  CCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCCCTGCCAAGGA
  GGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCCCAGGA
  CTCCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATGCAGGC
  GATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAGGAAGCTGCCCCC
  ACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGATCCCG
  GCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGGGAACT
  TCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCACGCCTGTTTA
  TGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCCCCTGG
  TCGCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGGCCCAG
  ACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCGGCCTGCCAGACT
  GCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAAAAAGA
  GGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAGCTGGG
  GAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGAACCCTGAGCT
  GGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGTGCTCT
  GCCCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGCCCCAC
  GGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGATCCCTGCCCTGGA
  GAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAGCTCCC
  TCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCACAAAGCGACCCAACTTTTGG
  CAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGCAGGACTCACCCC
  ACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATCAAGCA
  TAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTCAAGGC
  CACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTGAGCTCCTGTC
  CCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCCTTCTC
  CTGTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTGCAAAG
  GAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTGGCCCCAGCAGGG
  TGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGATGCTGG
  TGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCGTGCTAGCCTCACCAA
  ACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCTGCAAGAGCCC
  TGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTCCTCCC
  AGAGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGACTCAGG
  GGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAGCAAGGCCAACCG
  GCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGGTCACC
  AGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACGCCAAG
  CATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCGTGGTGTACAT
  TCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTGTTTGG
  TGAGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGCTTCAT
  CACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTGCCCTGAGGAA
  GCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGGCCCAG
  ATACACTGACTACGATTCCAATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGCAAGTA
  TGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAGCCTGCATTGATAACA
  GCCTTAACCCTCGAGGAATACCTCAATACCTCAGACAAGGCCCTTCCAATATGTTTACGT
  TTTCAAAGAAATCAAGTATATGAGGAGAGCGAGCGAGCGTGAGAGAACACCCGTGAGAGA
  GACTTGAAACTGCTGTCCTTTAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >Reverse primer walk for NM_133263 unedited
  NNGGCGTGCGTCACCGTACTGCAGCGCACTGTGCCGAGTGAGGTGCTTATGTAGTTCTGT
  ACAACTTCGGCTCTGAGACTGCATCATGGGAGCCTTCTTGTCTTGGGTGCTGTCCGCCTT
  AACACAGGCCGTTGACTTTTAGATCTGAGGCCTGCCTGGCGCCAGGCGGTCCCTTCCTTC
  TGGGTGTCAGAGCTTGATGTTGGGTAGGATGTGGCCAGGAGGAGCTTCTGCAGCAGTGAG
  AGCTCGTCCACCTCAGGGGCTGGGGCCGAGGGCTTCTCCGGGGCAGGGCTGGGGGGTGCA
  GATGAGGGGGCAGGCGAAGCTGAGGTGCATGATAGAGCGTCTCCACCATCCAGGGCTGGG
  AAGGCAGCCAGACCCACGTCATCTTCAGGGATGTCATCCAGGGTCTTGGTGAGCTCTGCC
  AGGAGGGCCTCATTCTCACTGTCAATCTGGAAGAGCTCGGAGTCATCGGGGCTGTACTGG
  TTGGGTTCAGTCTCTGAGTTCTCTGGGCACCACTGCAGCTCCCCAAAGCAGGTGGCCGAG
  TCAAAGTCGCTGGCATCCAGCTGGGAGAGGTCAAGTTCTGGAAAGTCAGCATAGAGTTGC
  TCCTCCCCGGACCCTCCACCCTGCGTGTCAGCGAGATAGTTGAGGAAGAAAGAGGAGAGC
  TCTTCGTCCAGCAGCGCGCCGCAGTCGTTCCCCGCCATCTTCCAGCCGCGGCTGCAGCGT
  GCGGCGGAGTCAACGCCGAGCCGGCCCGGNGGGGAGGGAGCCAGCGAGCGACCAAGGGAG
  GAAGGAGGAGGGAGTGAGGCCCGCGGGGAGCCGAAAGGCGNACCTCGACCCCCCGCTGCC
  GCAGGGCCGCTAGCTGCNGGGGCCGGGCCGCGCGCGCCCGCGGGAGCCGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133263 unedited
  AAACCTGGCAGCTTCTGGCAAGCTTGGGNAGCTGGCTGGGCTGTGGCATGTCGCAGGTGG
  GACAGGAGCTCACTTCGCTCTGGGTGCTTCTTTGGCAGCTTGTGGGCAGCCCCTGGGGTG
  GCCTTGAGTGAGAGGCCCTCAGGGGAGGGGAGGCTGAGAGCTATTTCTTTGCCTAGACTA
  TGCTTGATGTCTGGTTTGAAGGGATCCTCCTCTGTGGGCTTGTACGGTGGTGTGGTGGGT
  GGGGTGAGTCCTGCTGTGCCACAGAGCTCCACTGTCAAGGTCTGCTCAAAGCTCTTCTTG
  CCAAAAGTTGGGTCGCTTTGTGACAAGGCCAGCATGAGGCACCTGGGAGAGTCTCTGGGA
  GGGAGCTGCGGGCAGCTGGGGTCCTCATCCATGTCCCCACACCCACTCTCACAGGGGCTC
  TCCAGGGCAGGGATCTGGGGTCCCCGTAGGAGCTGCTGGTCTTGGCCACTGTCCTCGTCC
  GTGGGGCTGCCCAGCTCCCGCTCTACGTCGTAGGCCTTGGGAGCCAGGCACAGTGAGGGC
  AGAGCACCTTGGGGCTCCGAGGGGACCAGCGGCTCATCTGCAAATGTCAGCCAGGGGCCC
  AGCTCAAGGTTCAGTCTCCGAGAACGCCGCACGGNGCACACAGAGCTCTCCAGCTTCCTC
  CCCAGCTTCGTCCATGGCAGGCCTCGGCCTGGCCTTTTCCTGCCCCACTCCTCCTCCTCC
  TCTTTTTCTTCTCCTCTTCCTCCCTCTCTTCTTCCTCGTCTTCCTCCTCCTGCTGCTGCA
  GTCTGGCAGGCCGGGCGGACTCCCTTTTCACCTCCAGCCGCAGTGGGCGCAAGCTTGGTC
  TGGGCCCCGTGCTCCTGGGTGAAGCTGCGATCCTTACCTCCTCCACCCGAGACCGGCGAA
  CCAC
  
• Restriction Sites: Please inquire
• ACCN: NM_133263
• ORF Size: 3072 bp
• Insert Size: 3500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_133263.2, NP_573570.2
• RefSeq Size: 3277
• RefSeq ORF: 3072
• Locus ID: 133522
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.