NALP6 (NLRP6) (NM_138329) Human Untagged Clone

CAT#: SC306008

NLRP6 (untagged)-Human NLR family, pyrin domain containing 6 (NLRP6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP6
• Synonyms: AVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC306008 representing NM_138329
  Red=Cloning site Blue=ORF
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACCAGCCAGAGGCCCCCTGCTCCAGCACGGGGCCGCGCCTCGCGGTGGCCCGCGAGCTGCTCCTGG
  CTGCGCTGGAGGAACTGAGCCAAGAGCAGCTGAAGCGCTTCCGCCACAAGCTGCGCGACGTGGGCCCGGA
  CGGACGCAGCATCCCGTGGGGGCGGCTGGAGCGCGCGGACGCCGTGGACCTCGCGGAGCAGCTGGCCCAG
  TTCTACGGCCCGGAGCCTGCCCTGGAGGTGGCCCGCAAGACCCTCAAGAGGGCGGACGCGCGCGACGTGG
  CGGCGCAGCTCCAGGAGCGGCGGCTGCAGCGGCTCGGGCTCGGCTCCGGGACGCTGCTCTCCGTGTCCGA
  GTACAAGAAGAAGTACCGGGAGCACGTGCTGCAGCTGCACGCTCGGGTGAAGGAGAGGAACGCCCGCTCC
  GTGAAGATCACCAAGCGCTTCACCAAGCTGCTCATCGCGCCCGAGAGCGCCGCCCCGGAGGAGGCGATGG
  GGCCCGCGGAAGAGCCTGAGCCGGGGCGCGCGCGGCGCTCGGACACGCACACTTTCAACCGCCTCTTCCG
  CCGCGACGAGGAGGGCCGGCGGCCGCTGACCGTGGTGCTGCAGGGCCCGGCGGGCATCGGCAAGACCATG
  GCGGCCAAAAAGATCCTGTACGACTGGGCGGCGGGCAAGCTGTACCAGGGCCAGGTGGACTTCGCCTTCT
  TCATGCCCTGCGGCGAGCTGCTGGAGAGGCCGGGCACGCGCAGCCTGGCTGACCTGATCCTGGACCAGTG
  CCCCGACCGCGGCGCGCCGGTGCCGCAGATGCTGGCCCAGCCGCAGCGGCTGCTCTTCATCCTGGACGGC
  GCGGACGAGCTGCCGGCGCTGGGGGGCCCCGAGGCCGCGCCCTGCACAGACCCCTTCGAGGCGGCGAGCG
  GCGCGCGGGTGCTAGGCGGGCTGCTGAGCAAGGCGCTGCTGCCCACGGCCCTCCTGCTGGTGACCACGCG
  CGCCGCCGCCCCCGGGAGGCTGCAGGGCCGCCTGTGTTCCCCGCAGTGCGCCGAGGTGCGCGGCTTCTCC
  GACAAGGACAAGAAGAAGTATTTCTACAAGTATTTCCGGGATGAGAGGAGGGCCGAGCGCGCCTACCGCT
  TCGTGAAGGAGAACGAGACGCTGTTCGCGCTGTGCTTCGTGCCCTTCGTGTGCTGGATCGTGTGCACCGT
  GCTGCGCCAGCAGCTGGAGCTCGGTCGGGACCTGTCGCGCACGTCCAAGACCACCACGTCAGTGTACCTG
  CTTTTCATCACCAGCGTTCTGAGCTCGGCTCCGGTAGCCGACGGGCCCCGGTTGCAGGGCGACCTGCGCA
  ATCTGTGCCGCCTGGCCCGCGAGGGCGTCCTCGGACGCAGGGCGCAGTTTGCCGAGAAGGAACTGGAGCA
  ACTGGAGCTTCGTGGCTCCAAAGTGCAGACGCTGTTTCTCAGCAAAAAGGAGCTGCCGGGCGTGCTGGAG
  ACAGAGGTCACCTACCAGTTCATCGACCAGAGCTTCCAGGAGTTCCTCGCGGCACTGTCCTACCTGCTGG
  AGGACGGCGGGGTGCCCAGGACCGCGGCTGGCGGCGTTGGGACACTCCTGCGTGGGGACGCCCAGCCGCA
  CAGCCACTTGGTGCTCACCACGCGCTTCCTCTTCGGACTGCTGAGCGCGGAGCGGATGCGCGACATCGAG
  CGCCACTTCGGCTGCATGGTTTCAGAGCGTGTGAAGCAGGAGGCCCTGCGGTGGGTGCAGGGACAGGGAC
  AGGGCTGCCCCGGAGTGGCACCAGAGGTGACCGAGGGGGCCAAAGGGCTCGAGGACACCGAAGAGCCAGA
  GGAGGAGGAGGAGGGAGAGGAGCCCAACTACCCACTGGAGTTGCTGTACTGCCTGTACGAGACGCAGGAG
  GACGCGTTTGTGCGCCAAGCCCTGTGCCGGTTCCCGGAGCTGGCGCTGCAGCGAGTGCGCTTCTGCCGCA
  TGGACGTGGCTGTTCTGAGCTACTGCGTGAGGTGCTGCCCTGCTGGACAGGCACTGCGGCTGATCAGCTG
  CAGATTGGTTGCTGCGCAGGAGAAGAAGAAGAAGAGCCTGGGGAAGCGGCTCCAGGCCAGCCTGGGTGGC
  GGCAGCAGTTCTCAAGGCACCACAAAACAACTGCCAGCCTCCCTTCTTCATCCACTCTTTCAGGCAATGA
  CTGACCCACTGTGCCATCTGAGCAGCCTCACGCTGTCCCACTGCAAACTCCCTGACGCGGTCTGCCGAGA
  CCTTTCTGAGGCCCTGAGGGCAGCCCCCGCACTGACGGAGCTGGGCCTCCTCCACAACAGGCTCAGTGAG
  GCGGGACTGCGTATGCTGAGTGAGGGCCTAGCCTGGCCGCAGTGCAGGGTGCAGACGGTCAGGGTACAGC
  TGCCTGACCCCCAGCGAGGGCTCCAGTACCTGGTGGGTATGCTTCGGCAGAGCCCTGCCCTGACCACCCT
  GGATCTCAGCGGCTGCCAACTGCCCGCCCCCATGGTGACCTACCTGTGTGCAGTCCTGCAGCACCAGGGA
  TGCGGCCTGCAGACCCTCAGTCTGGCCTCTGTGGAGCTGAGCGAGCAGTCACTACAGGAGCTTCAGGCTG
  TGAAGAGAGCAAAGCCGGATCTGGTCATCACACACCCAGCGCTGGACGGCCACCCACAACCTCCCAAGGA
  ACTCATCTCGACCTTCTGA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: Please inquire
• ACCN: NM_138329
• ORF Size: 2763 bp
• Insert Size: 2700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF clone has been fully sequenced and found to be a perfect match to NM_138329.1.

Reference Data

• RefSeq: NM_138329.1, NP_612202.1
• RefSeq Size: 2763
• RefSeq ORF: 2763
• Locus ID: 171389
• Gene Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).