Neurexin II alpha (NRXN2) (NM_138732) Human Untagged Clone

CAT#: SC306070

NRXN2 (untagged)-Human neurexin 2 (NRXN2), transcript variant alpha-2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRXN2
• Synonyms: FLJ40892; KIAA0921
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138732, the custom clone sequence may differ by one or more nucleotides
  ATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTG
  GCGCTGGCGGCGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGC
  TACGCGCGCTGGGCGGGCGCGGCGAGCAGCGGCGAGCTCAGCTTCAGCCTGCGCACCAAC
  GCCACGCGCGCGCTGCTGCTCTACCTGGACGACGGCGGCGACTGCGACTTCCTGGAGCTG
  CTGCTGGTGGACGGCCGCCTGCGGCTGCGCTTCACGCTTTCGTGCGCCGAGCCGGCCACG
  CTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCTGACCCGCGAC
  GCGCGCCGCACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAG
  CGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGCCCGACGTGCGC
  CTCTCGGCGCTTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCC
  AACCTGAAGCTGGGCGAGCGGCCCCCCGCGCTGCTGGGCAGCCAGGGCCTGCGCGGCGCC
  ACCGCCGACCCGCTGTGCGCGCCCGCGCGCAACCCCTGCGCCAACGGCGGCCTCTGCACC
  GTGCTGGCCCCCGGCGAGGTGGGCTGCGACTGCAGCCACACGGGCTTCGGCGGCAAGTTC
  TGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAAACAGCGAAGGC
  AAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCACAC
  AACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACCCTGCAACGCAAC
  GGCCTGATGCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGG
  GCTGTCTGGCTGGTCATCAACCTAGGCTCAGGTGCCTTCGAGGCCCTTGTGGAACCCGTC
  AATGGCAAGTTCAACGACAACGCCTGGCACGACGTCCGGGTCACCCGAAACCTGCGCCAG
  CACGCAGGGATTGGACACGCTATGGTGACCATCTCGGTGGACGGGATCCTGACCACCACA
  GGCTACACGCAGGAGGATTACACCATGCTGGGCTCTGATGACTTCTTCTACATTGGGGGC
  AGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCAGCAACAACTTCATGGGCTGCCTC
  AAGGACGTGGTCTATAAGAACAATGACTTCAAATTGGAACTATCCCGCCTGGCAAAGGAA
  GGGGACCCCAAGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGGATGTGGCTGCC
  CTGGACCCTGTGACCTTTGAGAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCT
  AAGCGCACTGGCTCCATCTCCCTAGACTTCCGCACCACCGAGCCCAATGGGCTGCTGCTC
  TTCAGCCAGGGCCGGCGGGCTGGGGGTGGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCC
  GACTACTTTGCCATGGAGCTATTGGACGGCCACCTCTATCTTCTGCTGGACATGGGATCT
  GGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCAATGATGGCGAGTGGTGTCACGTG
  GACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCGCAGCACGCCGTTC
  TTGGCCACTGGAGACAGCGAGATTCTGGACCTGGAGAGTGAGCTGTACCTGGGCGGTCTC
  CCTGAGGGGGGCCGGGTGGACCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGG
  GCAGGCTACGTGGGCTGTGTGCGGGACCTCTTCATAGATGGGCGTAGCCGAGACCTCCGG
  GGCCTGGCTGAGGCTCAGGGGGCTGTGGGCGTTGCCCCCTTTTGCTCCCGGGAGACGCTG
  AAGCAGTGTGCATCTGCCCCCTGTCGCAATGGGGGCGTCTGTCGAGAAGGCTGGAACCGC
  TTCATCTGTGACTGCATCGGGACCGGCTTTCTTGGGCGGGTCTGTGAGAGAGAGGCCACG
  GTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAACGCCATGCACACG
  GAGGCAGAGGATGTGTCCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATGGCC
  ACCACTTCCAGGGAGTCTGCCGACACCCTACGCCTGGAGCTGGATGGGGGGCAGATGAAG
  CTCACTGTCAACCTCGGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAAGCTCAATGAC
  AATGAGTGGCACACGGTGAGGGTGGTCCGGCGTGGCAAGAGCCTGCAGCTGTCTGTGGAC
  AACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTTCCACAACATT
  GAGACGGGCATCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGG
  CATCTGAGTGGGCTCGTGTTCAATGGCCAGCCCTACATGGACCAGTGCAAGGATGGTGAC
  ATCACCTACTGTGAGCTCAATGCTCGCTTTGGCCTGCGTGCCATCGTGGCCGATCCCGTC
  ACCTTCAAGAGTCGCAGCAGCTACCTGGCACTCGCCACGCTCCAAGCCTATGCTTCCATG
  CACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGTTCAACTCGGGC
  AACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGAC
  CTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCAATGACAACCAG
  TGGCACAACGTGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCC
  CGCACTGTCACGCAGCACTCCAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTAC
  ATTGGCGGTCTGAGCAAGAATATGTTCAGCAACCTGCCCAAGCTGGTGGCCTCCCGGGAT
  GGCTTTCAGGGCTGCCTGGCCTCAGTGGACCTCAACGGACGTCTCCCAGACCTCATCGCC
  GACGCCCTGCACCGCATTGGGCAGGTGGAGAGGGGCTGTGATGGCCCCAGCACCACCTGC
  ACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGC
  GACTGCACCATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGACCACATACATC
  TTTGGGAAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACG
  AGGATGGATCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGG
  GTGGACAGCGCCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACCAGGGCACCGTG
  GGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCGACGAGCCCAACGCCATAGTA
  AGCGACGGCAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGCCACCCTGCAG
  GTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGCCGCCAGCTGACCATCTTCAAC
  AGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCAGGGCCAGGTG
  TCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGAGCGACCCCAAT
  GTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCG
  GAGACCACGGCCACCACCCTGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACC
  ACCATGGCCACTACCACCACGCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACC
  CAGAACACAGATGACCTGCTGGTGGCCTCTGCTGAGTGTCCAAGCGATGATGAGGACCTG
  GAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGCCCATTATCACGGAGGACTCC
  TTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCCTACCTTCTAC
  CCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGC
  CCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATC
  GAGGCCTCGGGCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGAC
  GAGGACTTTTACACCACCTTTCCCCTGGTCACGGACCGCACCACCCTCCTGTCACCCCGC
  AAACCCGCTCCCCGGCCCAACCTCAGGACAGATGGGGCCACGGGCGCCCCTGGGGTGCTG
  TTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGGCAAAATGAACCACCGAGACCCG
  CTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTCCTTTGAGCCG
  CGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCC
  ACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGGAGGTGATCCGG
  GAGTCCAGCAGCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATC
  CTCATCCTCCTCTACGCCATGTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTG
  GACCAGAGCCGAAACTACATCAGTAACTCGGCCCAGAGCAATGGGGCGGTGGTGAAAGAG
  AAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGAAGAACAAAGACAAGGAGTAT
  TATGTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_138732
• ORF Size: 4929 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_138732.1, NP_620060.1
• RefSeq Size: 6390
• RefSeq ORF: 4929
• Locus ID: 9379
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992). [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (alpha-2) lacks 3 exons and a portion from a fourth exon in the coding region, as compared to variant alpha-2. It encodes isoform alpha-2 which is missing 4 internal aa fragments but has identical N- and C-termini to isoform alpha-1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.