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Junctional Adhesion Molecule 1 (F11R) (NM_144502) Human Untagged Clone
CAT#: SC306150
F11R (untagged)-Human F11 receptor (F11R), transcript variant 3
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | F11R |
| Synonyms | JAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_144502 edited
CTGTTCCCAGGAGTCCTTCGGCGGCTGTTGTGTCGGGAGCCTGATCGCGATGGGGACAAA GGCGCAAGTCGAGAGGAAACTGTTGTGCCTCTTCATATTGGCGATCCTTCCTGAGAATAA TCCTGTGAAGTTGTCCTGTGCCTACTCGGGCTTTTCTTCTCCCCGTGCAGCTTCCTATGA GGACCGGGTGACCTTCTTGCCAACTGGTATCACCTTCAAGTCCGTGACACGGGAAGACAC TGGGACATACACTTGTATGGTCTCTGAGGAAGGCGGCAACAGCTATGGGGAGGTCAAGGT CAAGCTCATCGTGCTTGTGCCTCCATCCAAGCCTACAGTTAACATCCCCTCCTCTGCCAC CATTGGGAACCGGGCAGTGCTGACATGCTCAGAACAAGATGGTTCCCCACCTTCTGAATA CACCTGGTTCAAAGATGGGATAGTGATGCCTACGAATCCCAAAAGCACCCGTGCCTTCAG CAACTCTTCCTATGTCCTGAATCCCACAACAGGAGAGCTGGTCTTTGATCCCCTGTCAGC CTCTGATACTGGAGAATACAGCTGTGAGGCACGGAATGGGTATGGGACACCCATGACTTC AAATGCTGTGCGCATGGAAGCTGTGGAGCGGAATGTGGGGGTCATCGTGGCAGCCGTCCT TGTAACCCTGATTCTCCTGGGAATCTTGGTTTTTGGCATCTGGTTTGCCTATAGCCGAGG CCACTTTGACAGAACAAAGAAAGGGACTTCGAGTAAGAAGGTGATTTACAGCCAGCCTAG TGCCCGAAGTGAAGGAGAATTCAAACAGACCTCGTCATTCCTGGTGTGAGCCTGGTCGGC TCACCGCCTATCATCTGCATTTGCCTTACTCAGGTGCTACCGGACTCTGGCCCCTGATGT CTGTAGTTTCACAGGATGCCTTATTTGTCTTCTACACCCCACAGGGCCCCCTACTTCTTC GGATGTGTTTTTAATAATGTCAGCTATGTGCCCCATCCTCCTTCATGCCCTCCCTCCCTT TCCTACCACTGCTGAGTGGCCTGGAACTTGTTTAAAGTGTTTATTCCCCATTTCTTTGAG GGATCAGGAAGGAATCCTGGGTATGCCATTGACTTCCCTTCTAAGTAGACAGCAAAAATG GCGGGGGTCGCAGGAATCTGCACTCAACTGCCCACCTGGCTGGCAGGGATCTTTGAATAG GTATCTTGAGCTTGGTTCTGGGCTCTTTCCTTGTGTACTGACGACCAGGGCCAGCTGTTC TAGAGCGGGAATTAGAGGCTAGAGCGGCTGAAATGGTTGTTTGGTGATGACACTGGGGTC CTTCCATCTCTGGGGCCCACTCTCTTCTGTCTTCCCATGGGAAGTGCCACTGGGATCCCT CTGCCCTGTCCTCCTGAATACAAGCTGACTGACATTGACTGTGTCTGTGGAAAATGGGAG CTCTTGTTGTGGAGAGCATAGTAAATTTTCAGAGAACTTGAAGCCAAAAGGATTTAAAAC CGCTGCTCTAAAGAAAAGAAAACTGGAGGCTGGGCGCAGTGGCTCACGCCTATAATCCCA GAGGCTGAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGATCAGCCTGACCAACATGG AGAAACCCTACTAAAAATACAAAGTTAGCCAGGCATAGTGGTGCATGCCTGTAATCCCAG CTGCTCAGGAGCCTGGCAACAAGAGCAAAACTCCAGCTCAAAAAAAAAAAGAAAGAAAAG AAAGCTGGAGCTGGTGGCTTAGGCCATCACCCTTCCCTTGGCTGGAACTACTGGACAGAC CCTTTTGAGATGTGCCTGTGGTGCTGTGGAGATGTGTGTAGTGGTCTTAGCTCTTTGTTG AGCTTGTGTGTGTGTTGTGTAGTCTTAGCTGTATGCTGAAATTGGGCGTGTGTTGGAGGG CTTCTTAGCTCTTTGGTGAGATTGTATTTCTATGTGTTTGTATCAGCTGAATGTTGCTGG AAATAAAACCTTGGTTTGTCAAGGCTCTTTTTTGTGGGAAGTAAGTAGGGGAAAAGGTCT TTGAGGGTTCCTAGGCTCCTTTGTACAACAGGAAAATGCCTCAAAGCCTTGCTTCCCAGC AACCTGGGGCTGGTTCCCAGTGCCTGGTCCTGCCCCTTCCTGGTTCTTATCTCAAGGCAG AGCTTCTGAATTTCAGGCCTTCATTCCAGAGCCCTCTTGTGGCCAGGCCTTCCTTTGCTG GAGGAAGGTACACAGGGTGAAGCTGATGCTGTACTTGGGGGATCTCCTTGGCCTGTTCCA CCAAGTGAGAGAAGGTACTTACTCTTGTACCTCCTGTTCAGCCAGGTGCATTAACAGACC TCCCTACAGCTGTAGGAACTACTGTCCCAGAGCTGAGGCAAGGGGATTTCTCAGGTCATT TGGAGAACAAGTGCTTTAGTAGTAGTTTAAAGTAGTAACTGCTACTGTATTTAGTGGGGT GGAATTCAGAAGAAATTTGAAGACCAGATCATGGGTGGTCTGCATGTGAATGAACAGGAA TGAGCCGGACAGCCTGGCTGTCATTGCTTTCTTCCTCCCCATTTGGACCCTTCTCTGCCC TTACATTTTTGTTTCTCCATCTACCACCATCCACCAGTCTATTTATTAACTTAGCAAGAG GACAAGTAAAGGGCCCTCTTGGCTTGATTTTGCTTCTTTCTTTCTGTGGAGGATATACTA AGTGCGACTTTGCCCTATCCTATTTGGAAATCCCTAACAGAATTGAGTTTTCTATTAAGG ATCCAAAAAGAAAAACAAAATGCTAATGAAGCCATCAGTCAAGGGTCACATGCCAATAAA CAATAAATTTTCCAGAAGAAATGAAATCCAACTAGACAAATAAAGTAGAGCTTATGAAAT GGTTCAGTAAAGATGAGTTTGTTGTTTTTTGTTTTGTTTTGTTTTGTTTTTTTAAAGACG GAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTATGATCTTGGCTCACTGTAACCT CCGCCTCCCGGGTTCAAGCCATTCTCCTGCCTCAGTCTCCTGAGTAGCTGGGATTACGGG TGCGTGCCACCATGCCTGGCTAGTTTTTGTGTTTTTAGTAGAGACAGGGTTTCACCATGT TGGTCGGGCTGGTCTCGAACTCCTGACCTCTTGATCCGCCTGCCTTGGCCTCCCAAAGTG ATGGGATTACAGATGTGAGCCACCGTGCCTAGCCAAGGATGAGATTTTTAAAGTATGTTT CAGTTCTGTGTCATGGTTGGAAGACAGAGTAGGAAGGATATGGAAAAGGTCATGGGGAAG CAGAGGTGATTCATGGCTCTGTGAATTTGAGGTGAATGGTTCCTTATTGTCTAGGCCACT TGTGAAGAATATGAGTCAGTTATTGCCAGCCTTGGAATTTACTTCTCTAGCTTACAATGG ACCTTTTGAACTGGAAAACACCTTGTCTGCATTCACTTTAAAATGTCAAAACTAATTTTT ATAATAAATGTTTATTTTCACATTGAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_144502 unedited
GTTGCATTTGTATACGATCATATAGGGCGGCCGCGAATTCGCACGAGGCTGTTCCCAGNA GTCCTTCGGCGGCTGTTGTGTCGGGAGCCTGATCGCGATGGGGACAAAGGCGCAAGTCGA GAGGAAACTGTTGTGCCTCTTCATATTGGCGATCCTTCCTGAGAATAATCCTGTGAAGTT GTCCTGTGCCTACTCGGGCTTTTCTTCTCCCCGTGCAGCTTCCTATGAGGACCGGGTGAC CTTCTTGCCAACTGGTATCACCTTCAAGTCCGTGACACGGGAAGACACTGGGACATACAC TTGTATGGTCTCTGAGGAAGGCGGCAACAGCTATGGGGAGGTCAAGGTCAAGCTCATCGT GCTTGTGCCTCCATCCAAGCCTACAGTTAACATCCCCTCCTCTGCCACCATTGGGAACCG GGCAGTGCTGACATGCTCAGAACAAGATGGTTCCCCACCTTCTGAATACACCTGGTTCAA AGATGGGATAGTGATGCCTACGAATCCCAAAAGCACCCGTGCCTTCAACAACTCTTCCTA TGTCCTGAATCCCACAACAGGAGAGCTGGTCTTTGATCCCCTGTCAGCCTCTGATACTGG AGAATACAGCTGTGAGGCACGGAATGGGTATGGGACACCCTTGACTTTCAATGCTGTGCG CATTGGAACTGTGGAGCGGAATGTGGGGGTCATCGTGGCAGCCGTCCTTGTAACCCTGAT TCTCCGGGAAATCTTGGTTTTTGGCATTTGGTTTTGCCTATTACCGAAGCCCCTTTTGCC GAACCAAGAAAGGGACTTCGATTAAAAAGGGATTTAAAGCCCCCT |
| Restriction Sites | Please inquire |
| ACCN | NM_144502 |
| ORF Size | 780 bp |
| Insert Size | 3500 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Reference Data | |
| RefSeq | NM_144502.1, NP_653085.1 |
| RefSeq Size | 3527 |
| RefSeq ORF | 780 |
| Locus ID | 50848 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction |
| Gene Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks two in-frame coding segments compared to variant 1, resulting in a shorter isoform (b) lacking two internal aa segments. |
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