IL23 Receptor (IL23R) (NM_144701) Human Untagged Clone

CAT#: SC306188

IL23R (untagged)-Human interleukin 23 receptor (IL23R)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL23R
• Synonyms: interleukin 23 receptor; OTTHUMP00000010660
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_144701, RT-PCR generated
  CTTTTCCTGCTTCCAGACATGAATCATGTCACTATTCAATGGGATGCAGTAATAGCCCTT
  TACATACTCTTCAGCTGGTGTCATGGAGGAATTACAAATATAAACTGCTCTGGCCACATC
  TGGGTAGAACCAGCCACAATTTTTAAGATGGGTATGAATATCTCTATATATTGCCAAGCA
  GCAATTAAGAACTGCCAACCAAGGAAACTTCATTTTTATAAAAATGGCATCAAAGAAAGA
  TTTCAAATCACAAGGATTAATAAAACAACAGCTCGGCTTTGGTATAAAAACTTTCTGGAA
  CCACATGCTTCTATGTACTGCACTGCTGAATGTCCCAAACATTTTCAAGAGACACTGATA
  TGTGGAAAAGACATTTCTTCTGGATATCCGCCAGATATTCCTGATGAAGTAACCTGTGTC
  ATTTATGAATATTCAGGCAACATGACTTGCACCTGGAATGCTGGGAAGCTCACCTACATA
  GACACAAAATACGTGGTACATGTGAAGAGTTTAGAGACAGAAGAAGAGCAACAGTATCTC
  ACCTCAAGCTATATTAACATCTCCACTGATTCATTACAAGGTGGCAAGAAGTACTTGGTT
  TGGGTCCAAGCAGCAAACGCACTAGGCATGGAAGAGTCAAAACAACTGCAAATTCACCTG
  GATGATATAGTGATACCTTCTGCAGCCGTCATTTCCAGGGCTGAGACTATAAATGCTACA
  GTGCCCAAGACCATAATTTATTGGGATAGTCAAACAACAATTGAAAAGGTTTCCTGTGAA
  ATGAGATACAAGGCTACAACAAACCAAACTTGGAATGTTAAAGAATTTGACACCAATTTT
  ACATATGTGCAACAGTCAGAATTCTACTTGGAGCCAAACATTAAGTACGTATTTCAAGTG
  AGATGTCAAGAAACAGGCAAAAGGTACTGGCAGCCTTGGAGTTCACCGTTTTTTCATAAA
  ACACCTGAAACAGTTCCCCAGGTCACATCAAAAGCATTCCAACATGACACATGGAATTCT
  GGGCTAACAGTTGCTTCCATCTCTACAGGGCACCTTACTTCTGACAACAGAGGAGACATT
  GGACTTTTATTGGGAATGATCGTCTTTGCTGTTATGTTGTCAATTCTTTCTTTGATTGGG
  ATATTTAACAGATCATTCCGAACTGGGATTAAAAGAAGGATCTTATTGTTAATACCAAAG
  TGGCTTTATGAAGATATTCCTAATATGAAAAACAGCAATGTTGTGAAAATGCTACAGGAA
  AATAGTGAACTTATGAATAATAATTCCAGTGAGCAGGTCCTATATGTTGATCCCATGATT
  ACAGAGATAAAAGAAATCTTCATCCCAGAACACAAGCCTACAGACTACAAGAAGGAGAAT
  ACAGGACCCCTGGAGACAAGAGACTACCCGCAAAACTCGCTATTCGACAATACTACAGTT
  GTATATATTCCTGATCTCAACACTGGATATAAACCCCAAATTTCAAATTTTCTGCCTGAG
  GGAAGCCATCTCAGCAATAATAATGAAATTACTTCCTTAACACTTAAACCACCAGTTGAT
  TCCTTAGACTCAGGAAATAATCCCAGGTTACAAAAGCATCCTAATTTTGCTTTTTCTGTT
  TCAAGTGTGAATTCACTAAGCAACACAATATTTCTTGGAGAATTAAGCCTCATATTAAAT
  CAAGGAGAATGCAGTTCTCCTGACATACAAAACTCAGTAGAGGAGGAAACCACCATGCTT
  TTGGAAAATGATTCACCCAGTGAAACTATTCCAGAACAGACCCTGCTTCCTGATGAATTT
  GTCTCCTGTTTGGGGATCGTGAATGAGGAGTTGCCATCTATTAATACTTATTTTCCACAA
  AATATTTTGGAAAGCCACTTCAATAGGATTTCACTCTTGGAAAAGTAGAGCTGTGTGGTC
  AAAATCAATATGAGAAAGCTGCCTTGCAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_144701 unedited
  GGGACGTCAAAAATTGTATACGACTCACTATAGGCGGCCGCGNAATCAAATCTGGTACCG
  ATATCAAGCTTGGTACCGAGCTCGNGACCACTAGTAACGGCCGCCAGTGTGCTGGAATTC
  GCCCTTGAGGGTACCTTTTCCTGCTTCCAGACATGAATCATGTCACTATTCAATGGGATG
  CAGTAATAGCCCTTTACATACTCTTCAGCTGGTGTCATGGAGGAATTACAAATATAAACT
  GCTCTGGCCACATCTGGGTAGAACCAGCCACAATTTTTAAGATGGGTATGAATATCTCTA
  TATATTGCCAAGCAGCAATTAAGAACTGCCAACCAAGGAAACTTCATTTTTATAAAAATG
  GCATCAAAGAAAGATTTCAAATCACAAGGATTAATAAAACAACAGCTCGGCTTTGGTATA
  AAAACTTTCTGGAACCACATGCTTCTATGTACTGCACTGCTGAATGTCCCAAACATTTTC
  AAGAGACACTGATATGTGGAAAAGACATTTCTTCTGGATATCCGCCAGATATTCCTGATG
  AAGTAACCTGTGTCATTTATGAATATTCAGGCAACATGACTTGCACCTGGAATGCTGGGA
  AGCTCACCTACATAGACACAAAATACGTGGTACATGTNGAAGAGTTTAGAGACAGAAGAA
  GAGCAACAGTATCTCACCTCAAGCTATATTAACATCTCCACTGATTCATTACAAGGTGGC
  AAGAGTTACTTTGGTTTTGGGTCCAAGCAGCAAACGCACTNAGNATGGGAAGAGTCAAAA
  CAACTGCAAATTACCCTGGATGATATAGTGATACCTTCTGCAGCCGTCATTTCCAGGGCT
  GAGACTATAATGGCTACAGTGCCCAAGACCATNATTTATTGGGGATA
  
• Restriction Sites: Please inquire
• ACCN: NM_144701
• ORF Size: 1890 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This construct is a cloned PCR fragment that was fully sequenced. While there are 2 nucleotide differences between the OriGene clone and the NCBI reference ORF, these differences are supported by other cDNA references within Genbank. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 2 amino acids.

Reference Data

• RefSeq: NM_144701.2, NP_653302.2
• RefSeq Size: 2826
• RefSeq ORF: 1890
• Locus ID: 149233
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]