LRDD (PIDD1) (NM_145886) Human Untagged Clone

CAT#: SC306285

PIDD (untagged)-Human p53-induced death domain protein (PIDD), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIDD1
• Synonyms: LRDD; PIDD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_145886, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTGCAACGGTGGAGGGGCCAGAGCTGGAGGCAGCTGCTGCCGCAGGAGATGCTTCAGAGGATTCGG
  ACGCAGGGTCCAGGGCGCTGCCTTTCCTGGGCGGCAACCGGCTGAGCTTGGACCTGTACCCCGGGGGCTG
  CCAGCAGCTGCTGCACCTGTGTGTCCAGCAGCCTCTGCAGCTGCTGCAGGTGGAATTCTTGCGTCTGAGC
  ACTCACGAGGACCCTCAGCTGCTGGAGGCCACCCTGGCCCAGCTGCCTCAGAGCCTGTCCTGCCTCCGCT
  CCCTGGTCCTCAAAGGAGGGCAACGCCGGGACACACTGGGTGCCTGTCTCCGGGGTGCCCTGACCAACCT
  GCCCGCTGGTCTGAGTGGCCTGGCCCATCTGGCCCACCTGGACCTGAGCTTCAACAGCCTGGAGACACTG
  CCGGCCTGTGTCCTGCAGATGCGAGGTCTGGGTGCGCTCTTGCTGTCTCACAACTGCCTCTCTGAGCTGC
  CTGAGGCTCTGGGGGCCCTCCCCGCCCTCACCTTCCTCACAGTGACACACAACCGCCTGCAGACGCTGCC
  CCCAGCACTGGGGGCCCTATCCACCCTGCAGCGCCTCGATCTCTCTCAGAATCTGCTGGACACGCTACCT
  CCTGAGATTGGAGGCCTGGGCAGCCTCCTGGAGCTCAACCTGGCCTCCAACCGGCTGCAGAGCCTCCCAG
  CCTCTCTGGCGGGACTTCGGTCCTTGCGGCTCCTTGTCCTGCACAGCAACCTCCTGGCCTCTGTGCCAGC
  TGACTTGGCCCGCCTTCCACTCCTCACCCGGCTCGACCTGAGGGACAACCAGCTCCGGGACCTGCCCCCT
  GAGCTGCTAGACGCCCCCTTTGTGCGCCTGCAGGGGAACCCCCTGGGTGAGGCCTCGCCAGACGCCCCGA
  GTTCACCAGTGGCAGCCCTCATTCCAGAAATGCCCAGACTGTTCCTGACCTCAGATTTGGACAGCTTTCC
  TGTGACCCCTCAAGGCTGCTCAGTGACCCTGGCCTGTGGCGTCCGCCTGCAGTTCCCAGCGGGAGCCACC
  GCCACCCCCATCACCATCCGCTATCGGCTGCTGCTGCCGGAGCCAGGCCTCGTCCCCCTGGGTCCTCATG
  ACGCCCTGCTCAGCCATGTGCTGGAGCTGCAGCCCCATGGGGTGGCCTTCCAGCAGGATGTGGGGCTGTG
  GCTGCTCTTCACCCCACCGCAGGCCCGGCGCTGCCGTGAAGTGGTGGTCAGGACCCGGAATGACAACAGC
  TGGGGTGACCTGGAGACCTACCTGGAGGAAGAGGCACCCCAGCGGCTCTGGGCTCACTGCCAGGTGCCCC
  ACTTCTCCTGGTTCCTTGTGGTTTCCCGCCCTGTGTCCAATGCCTGCCTGGTGCCACCGGAGGGGACACT
  GCTGTGCTCCTCGGGTCATCCTGGGGTCAAAGTCATCTTCCCCCCTGGGGCCACTGAGGAGCCTCGTCGA
  GTCTCCATGCAGGTGGTGCGCATGGCTGGCCGAGAGCTGCAGGCCCTCCTGGGAGAACCAGAGGCTGCAG
  TGAGCCCCCTGCTGTGCCTGTCACAGAGCGGTCCCCCCAGCTTCCTCCAACCGGTCACCGTGCAGCTGCC
  TCTGCCCTCTGGCATCACAGGCCTCAGTCTGGACCGCTCCCGCCTGCACCTGTTGTACTGGGCCCCTCCT
  GCAGCCACCTGGGATGACATCACAGCTCAGGTGGTCCTGGAGCTCACCCACCTGTACGCACGCTTCCAGG
  TCACACACTTCTCCTGGTACTGGCTCTGGTACACCACCAAGAACTGTGTGGGAGGCCTGGCTCGGAAGGC
  CTGGGAGCGGCTGCGGCTGCACCGTGTGAACCTCATCGCTCTGCAGCGGCGCCGGGACCCTGAGCAGGTC
  CTGCTGCAGTGCCTGCCCCGAAACAAGGTGGACGCCACCCTTCGGCGGCTGCTGGAGCGGTACCGGGGCC
  CCGAGCCCTCTGACACGGTGGAGATGTTCGAGGGCGAAGAGTTCTTTGCGGCCTTCGAGCGCGGCATCGA
  CGTGGATGCTGACCGCCCTGACTGTGTGGAGGGCAGAATCTGCTTTGTCTTCTACTCGCACCTGAAGAAT
  GTGAAGGAGGTATACGTGACCACCACTCTGGACCGGGAGGCTCAGGCTGTGCGGGGCCAGGTGTCCTTCT
  ACCGTGGCGCGGTGCCTGTGCGGGTGCCCGAGGAGGCTGAGGCTGCCCGGCAGAGGAAGGGCGCAGACGC
  CCTGTGGATGGCCACTCTGCCCATCAAGCTGCCGAGACTTCGAGGGTCCGAGGGGCCACGGCGGGGGGCT
  GGCCTCTCCTTGGCACCCTTGAATCTGGGAGATGCCGAGACCGGCTTTCTGACGCAGAGCAACCTGCTGA
  GTGTGGCTGGGCGTCTGGGTCTGGACTGGCCAGCCGTGGCCCTGCACCTGGGGGTGTCCTACCGGGAGGT
  GCAGCGCATCCGGCACGAGTTCCGGGATGATCTGGATGAGCAGATCCGTCACATGCTCTTCTCCTGGGCT
  GAGCGCCAGGCTGGGCAGCCAGGGGCTGTGGGGCTCCTGGTGCAGGCCCTGGAGCAGAGTGACCGGCAGG
  ACGTGGCTGAAGAGGTGCGCGCAGTCTTGGAGCTCGGCCGCCGCAAGTACCAGGACAGCATCCGACGCAT
  GGGCTTGGCCCCCAAGGACCCCGCTCTGCCTGGCTCCTCGGCTCCACAGCCCCCAGAGCCTGCCCAGGCC
  TAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_145886
• ORF Size: 2733 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_145886.3, NP_665893.2
• RefSeq Size: 3022
• RefSeq ORF: 2733
• Locus ID: 55367
• Protein Families: Druggable Genome
• Protein Pathways: p53 signaling pathway
• Gene Summary: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).