SNX1 (NM_148955) Human Untagged Clone

CAT#: SC306335

SNX1 (untagged)-Human sorting nexin 1 (SNX1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SNX1
• Synonyms: HsT17379; VPS5
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_148955 edited
  GAAGAAGATGGCGTCGGGTGGTGGTGGCTGTAGCGCTTCGGAGAGACTGCCTCCGCCCTT
  CCCCGGCCTGGAGCCGGAGTCCGAGGGGGCGGCCGGGGGATCAGAACCCGAGGCTGGGGA
  CAGCGACACCGAGGGGGAGGACATTTTCACCGGCGCCGCGGTGGTCAGTAAACATCAGTC
  TCCAAAGATAACTACATCCCTTCTTCCCATCAACAATGGCTCCAAAGAAAATGGGATCCA
  TGAAGAACAAGACCAAGAGCCACAGGATCTCTTTGCAGGGGATGGTATGAATGCATATGT
  AGCCTACAAAGTTACAACACAGACAAGCTTACCATTGTTCAGAAGCAAACAGTTTGCAGT
  AAAAAGAAGATTTAGTGACTTTCTGGGTCTTTATGAGAAGCTTTCCGAGAAGCACTCTCA
  GAATGGCTTCATTGTCCCTCCACCCCCGGAGAAGAGCCTCATAGGGATGACAAAAGTGAA
  AGTTGGGAAGGAAGATTCTTCTTCTGCAGAATTTCTTGAAAAACGGAGGGCCGCTTTAGA
  AAGGTACCTTCAGAGGATTGTAAATCATCCTACCATGTTACAGGACCCTGACGTCAGAGA
  GTTCTTGGAAAAAGAAGAGCTGCCACGTGCCGTGGGTACCCAGACATTGAGTGGTGCTGG
  TCTCCTCAAGATGTTCAACAAAGCCACAGATGCCGTCAGCAAAATGACCATCAAGATGAA
  TGAATCAGACATTTGGTTTGAGGAGAAGCTCCAGGAGGTAGAGTGTGAGGAGCAGCGCTT
  ACGGAAACTGCATGCTGTTGTAGAAACTCTAGTCAACCATAGGAAAGAGCTAGCGCTGAA
  CACAGCCCAGTTTGCAAAGAGTCTAGCCATGCTTGGGAGCTCTGAGGACAACACGGCATT
  GTCACGGGCACTCTCCCAGCTGGCTGAGGTGGAAGAAAAAATTGAGCAGCTCCACCAGGA
  ACAGGCCAACAATGACTTCTTCCTCCTTGCTGAGCTCCTGAGTGACTACATTCGCCTCCT
  GGCCATAGTCCGCGCTGCCTTCGACCAGCGCATGAAGACATGGCAGCGCTGGCAGGATGC
  CCAAGCCACACTGCAGAAGAAGCGGGAGGCCGAGGCTCGGCTGCTGTGGGCCAACAAGCC
  TGATAAGCTGCAGCAGGCCAAGGACGAGATCCTCGAGTGGGAGTCTCGGGTGACTCAATA
  TGAAAGGGACTTCGAGAGGATTTCAACAGTGGTCCGAAAAGAAGTGATACGGTTTGAGAA
  AGAGAAATCCAAGGACTTCAAGAACCACGTGATCAAGTACCTTGAGACACTCCTTTACTC
  ACAGCAGCAGCTGGCAAAGTACTGGGAAGCCTTCCTTCCTGAGGCAAAGGCCATCTCCTA
  ATGGACCAAGGACCCCAGAGCCCACCTGTGTGACGCTGCCTTTTTATACACTGTCCTCCT
  CCACCTTGATGGACCCCTAGTGATGCATCCTGCCTAGGCTGGACTTAACCCCTTCCTCCC
  TGTCCCCACGACCAACTGTCCCCAGTTACTCTAACCGTTATTTCATTTAGCTTCCATATA
  TATTTTCTTACCTAAGAGAATAGTTTCCTGCTTTAAGCAAAAGACCTACAATAGGTGGTG
  GAATTATGGGATGGGGTGGAGTATTGATATAAATATATAAATACAAATGTATATTTTTCA
  GGATGTGGTTTAGGAACTGGGAATAACGTTTTCTGTTACTCCTGATGGTGCCA
  
• Restriction Sites: Please inquire
• ACCN: NM_148955
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_148955.2, NP_683758.1
• RefSeq Size: 8026 bp
• RefSeq ORF: 1374 bp
• Locus ID: 6642
• Cytogenetics: 15q22.31
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. It encodes a shorter isoform (b), also known as SNX1A, that is missing an internal segment compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.