PANK1 (NM_148977) Human Untagged Clone

CAT#: SC306349

PANK1 (untagged)-Human pantothenate kinase 1 (PANK1), transcript variant alpha

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PANK1
• Synonyms: PANK
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_148977, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTGAAACTCGTCGGTGGCGGTGGCGGGCAGGACTGGGCATGCTCAGTGGCGGGGACCAGTCTGGGAG
  GCGAGGAAGCCGCGTTTGAAGTCGCGCGGCCTGGGGATCAGGGGAAGGCGGGCGGCGGGAGCCCCGGCTG
  GGGGTGCGCGGGGATCCCCGATTCCGCGCCCGGGGCTGGCGTGCTCCAGGCCGGCGCCGTGGGGCCGGCG
  CGCGGGGGGCAGGGCGCAGAGGAGGTGGGGGAGTCGGCAGGAGGAGGGGAGGAGCGCCGGGTTCGCCATC
  CCCAGGCGCCGGCTCTGCGGCTGCTGAATCGGAAGCCGCAGGGAGGATCCGGGGAAATAAAGACGCCGGA
  GAATGACCTCCAGCGAGGCCGCCTGAGCCGGGGCCCGCGCACAGCCCCGCCAGCCCCCGGCATGGGCGAC
  CGCAGCGGGCAGCAGGAGCGCTCGGTCCCGCACTCTCCAGGGGCCCCCGTGGGCACCAGCGCCGCCGCTG
  TGAACGGGCTGCTGCACAACGGCTTCCATCCGCCGCCAGTCCAGCCGCCGCACGTCTGCAGCCGGGGTCC
  AGTGGGCGGCAGCGACGCGGCGCCCCAGCGCCTCCCGCTCCTGCCGGAGCTGCAGCCGCAGCCACTGCTC
  CCTCAGCATGACTCCCCGGCCAAGAAATGCCGGCTGCGGAGGAGGATGGACTCGGGGAGAAAGAACAGGC
  CGCCATTCCCATGGTTTGGCATGGACATCGGTGGAACGCTGGTTAAATTGGTGTATTTCGAGCCGAAGGA
  TATTACAGCCGAAGAGGAGCAAGAGGAAGTGGAGAACCTGAAGAGCATCCGGAAGTATTTGACTTCTAAT
  ACTGCTTATGGGAAAACTGGGATCCGAGACGTCCACCTGGAACTGAAAAACCTGACCATGTGTGGACGCA
  AAGGGAACCTGCACTTCATCCGCTTTCCCAGCTGTGCTATGCACAGGTTCATTCAGATGGGCAGCGAGAA
  GAACTTCTCTAGCCTTCACACCACCCTCTGTGCCACAGGAGGCGGGGCTTTCAAATTCGAAGAGGACTTC
  AGAATGATTGCTGACCTGCAGCTGCATAAACTGGATGAACTGGACTGTCTGATTCAGGGCCTGCTTTATG
  TCGACTCTGTTGGCTTCAACGGCAAGCCAGAATGTTACTATTTTGAAAATCCCACAAATCCTGAATTGTG
  TCAAAAAAAGCCGTACTGCCTTGATAACCCATACCCTATGTTGCTGGTTAACATGGGCTCAGGTGTCAGC
  ATTCTAGCCGTGTACTCCAAGGACAACTATAAAAGAGTTACAGGGACCAGTCTTGGAGGTGGAACATTCC
  TAGGCCTATGTTGCTTGCTGACTGGTTGTGAGACCTTTGAAGAAGCTCTGGAAATGGCAGCTAAAGGCGA
  CAGCACCAATGTTGATAAACTGGTGAAGGACATTTACGGAGGAGACTATGAACGATTTGGCCTTCAAGGA
  TCTGCTGTAGCATCAAGCTTTGGCAACATGATGAGTAAAGAAAAGCGAGATTCCATCAGCAAGGAAGACC
  TCGCCCGGGCCACATTGGTCACCATCACCAACAACATTGGCTCCATTGCTCGGATGTGCGCGTTGAATGA
  GAACATAGACAGAGTTGTGTTTGTTGGAAATTTTCTCAGAATCAATATGGTCTCCATGAAGCTGCTGGCA
  TATGCCATGGATTTTTGGTCCAAAGGACAACTGAAAGCTCTGTTTTTGGAACATGAGGGTTATTTTGGAG
  CCGTTGGGGCACTGTTGGAACTGTTCAAAATGACTGATGACAAGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_148977
• ORF Size: 1797 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_148977.2, NP_683878.1
• RefSeq Size: 6976
• RefSeq ORF: 1797
• Locus ID: 53354
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pantothenate and CoA biosynthesis
• Gene Summary: This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (alpha) represents the longest transcript and encodes the longest isoform (alpha). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.