BDNF (NM_170734) Human Untagged Clone
CAT#: SC306691
BDNF (untagged)-Human brain-derived neurotrophic factor (BDNF), transcript variant 6
"NM_170734" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | BDNF |
Synonyms | ANON2; BULN2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_170734 edited
ATGCAGAGCCGGGAAGAGGAATGGTTCCACCAGGTGAGAAGAGTGATGACCATCCTTTTC CTTACTATGGTTATTTCATACTTTGGTTGCATGAAGGCTGCCCCCATGAAAGAAGCAAAC ATCCGAGGACAAGGTGGCTTGGCCTACCCAGGTGTGCGGACCCATGGGACTCTGGAGAGC GTGAATGGGCCCAAGGCAGGTTCAAGAGGCTTGACATCATTGGCTGACACTTTCGAACAC GTGATAGAAGAGCTGTTGGATGAGGACCAGAAAGTTCGGCCCAATGAAGAAAACAATAAG GACGCAGACTTGTACACGTCCAGGGTGATGCTCAGTAGTCAAGTGCCTTTGGAGCCTCCT CTTCTCTTTCTGCTGGAGGAATACAAAAATTACCTAGATGCTGCAAACATGTCCATGAGG GTCCGGCGCCACTCTGACCCTGCCCGCCGAGGGGAGCTGAGCGTGTGTGACAGTATTAGT GAGTGGGTAACGGCGGCAGACAAAAAGACTGCAGTGGACATGTCGGGCGGGACGGTCACA GTCCTTGAAAAGGTCCCTGTATCAAAAGGCCAACTGAAGCAATACTTCTACGAGACCAAG TGCAATCCCATGGGTTACACAAAAGAAGGCTGCAGGGGCATAGACAAAAGGCATTGGAAC TCCCAGTGCCGAACTACCCAGTCGTACGTGCGGGCCCTTACCATGGATAGCAAAAAGAGA ATTGGCTGGCGATTCATAAGGATAGACACTTCTTGTGTATGTACATTGACCATTAAAAGG GGAAGATAGTGGATTTATGTTGTATAGATTAGATTATATTGAGACAAAAATTATCTATTT GTATATATACATAACAGGGTAAATTATTCAGTTAAGAAAAAAATAATTTTATGAACTGCA TGTATAAATGAAGTTTATACAGTACAGTGGTTCTACAATCTATTTATTGGACATGTCCAT GACCAGAAGGGAAACAGTCATTTGCGCACAACTTAAAAAGTCTGCATTACATTCCTTGAT AATGTTGTGGTTTGTTGCCGTTGCCAAGAACTGAAAACATAAAAAGTTAAAAAAAATAAT AAATTGCATGCTGCTTTAATTGTGAATTGAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_170734 unedited
GTTCAGTTCACATTTGTATACGACTCATATAGGCGGCCGCGNATTCATGCAGAGCCGGGA AGAGGAATGGTTCCACCAGGTGAGAAGAGTGATGACCATCCTTTTCCTTACTATGGTTAT TTCATACTTTGGTTGCATGAAGGCTGCCCCCATGAAAGAAGCAAACATCCGAGGACAAGG TGGCTTGGCCTACCCAGGTGTGCGGACCCATGGGACTCTGGAGAGCGTGAATGGGCCCAA GGCAGGTTCAAGAGGCTTGACATCATTGGCTGACACTTTCGAACACGTGATAGAAGAGCT GTTGGATGAGGACCAGAAAGTTCGGCCCAATGAAGAAAACAATAAGGACGCAGACTTGTA CACGTCCAGGGTGATGCTCAGTAGTCAAGTGCCTTTGGAGCCTCCTCTTCTCTTTCTGCT GGAGGAATACAAAAATTACCTAGATGCTGCAAACATGTCCATGAGGGTCCGGCGCCACTC TGACCCTGCCCGCCGAGGGGAGCTGAGCGTGTGTGACAGTATTAGTGAGTGGGTAACGGC GGCAGACAAAAAGACTGCAGTGGACATGTCGGGCGGGACGGTCACAGTCCTTGAAAAGGT CCCTGTATCAAAAGGCCAACTGAAGCAATACTTCTACGAGACCAAGTGCAATCCCATGGG TTACACAAAAGAAAGCTGCAGGGGCATAGACAAAAGGCATTGGAACTCCCAGTGCCGAAC TACCCAGTCGTACGTGCGGGCCCTTACCATGGATAGCANNAAGAAATTGGCTGGCGATTC ATAAGGATAGACACTTCTTGTGTATGTACATTGACCATTAAAGGGGGAGATAGTGGNATT ATGTN >Forward primer walk for NM_170734 unedited
GATCAGTAGGATTGTGNNACCCTGTACTGTATAAACTTCATTTATACATGCAGTTCATAA AATATTTTTTTCTTAACTGAATAATTTACCCTGTTATGTATATATACAAATAGATAATTT TTGTCTCAATATAATCTAATCTATACAACATAAATCCACTATCTTCCCCTTTTAATGGTC AATGTACATACACAAGAAGTGTCTATCCTTATGAATCGCCAGCCAATTCTCTTTTTGCTA TCCATGGTAAGGGCCCGCACGTACGACTGGGTAGTTCGGCACTGGGAGTTCCAATGCCTT TTGTCTATGCCCCTGCAGCCTTCTTTTGTGTAACCCATGGGATTGCACTTGGTCTCGTAG AAGTATTGCTTCAGTTGGCCTTTTGATACAGGGACCTTTTCAAGGACTGTGACCGTCCCG CCCGACATGTCCACTGCAGTCTTTTTGTCTGCCGCCGTTACCCACTCACTAATACTGTCA CACACGCTCAGCTCCCCTCGGCGGGCAAGGTCAAAGTGGCGCCAGACCCCTCTGGACATG TTTGCAACATCTAAGAAATTTTTGAATCCCCCACCAAAAAAAAGAAAAGAAGCTCCAAAA GCACTTGACTACTGGACCACACCCTAGGACAGGTAAAAAGTCTGCCACCCTAATGGTTAT CTAACAAGGGACCCAAATTTTCTGGACCCCCAAACAAAAAACTCTTAGTATAAACGTTTA AAAAAAGGAGTAACCCCAATGGAGTCCAGACCTCATGGAAAACAGCCGTGGGGAGAAAAA TAAAGAAACACACAAAACACCAAAAGAGACCCCACAAACGTGGTTAGAGAAAAAAAACCC AAGGGACCGGAAAGGATACCCATAGTCTCAAGCGACACAAACCACAAAAGGCACACAAAA GAGAGGAGAACAAACAGTAGAAANAAGAGAAGATGTAGGAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_170734 |
Insert Size | 1100 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_170734.2, NP_733930.1 |
RefSeq Size | 3958 bp |
RefSeq ORF | 789 bp |
Locus ID | 627 |
Cytogenetics | 11p14.1 |
Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane |
Protein Pathways | Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway |
Gene Summary | 'This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]' Transcript Variant: This variant (6), also known as VIIb, BDNF6B, or 4I-5, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (c) contains a longer N-terminus and lacks a predicted signal peptide compared to isoform a. |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC217124 | BDNF (Myc-DDK-tagged)-Human brain-derived neurotrophic factor (BDNF), transcript variant 6 |
USD 98.00 |
|
RG217124 | BDNF (GFP-tagged) - Human brain-derived neurotrophic factor (BDNF), transcript variant 6 |
USD 460.00 |
|
RC217124L1 | Lenti ORF clone of Human brain-derived neurotrophic factor (BDNF), transcript variant 6, Myc-DDK-tagged |
USD 620.00 |
|
RC217124L2 | Lenti ORF clone of Human brain-derived neurotrophic factor (BDNF), transcript variant 6, mGFP tagged |
USD 620.00 |
|
RC217124L3 | Lenti ORF clone of Human brain-derived neurotrophic factor (BDNF), transcript variant 6, Myc-DDK-tagged |
USD 620.00 |
|
RC217124L4 | Lenti ORF clone of Human brain-derived neurotrophic factor (BDNF), transcript variant 6, mGFP tagged |
USD 620.00 |
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