NFAT1 (NFATC2) (NM_173091) Human Untagged Clone

CAT#: SC306788

NFATC2 (untagged)-Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 2


  "NM_173091" in other vectors (6)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NFATC2
Synonyms NFAT1; NFATP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_173091 edited
AGCAGGAAGCTCGCGCCGCCGTCGCCGCCGCCGCTCAGCTTCCCCGGGCGCGTCCAGGAC
CCGCTGCGCCAGGCGCGCCGTCCCCGGACCCGGCGTGCGTCCCTACGAGGAAAGGGACCC
CGCCGCTCGAGCCGCCTCCGCCAGCCCCACTGCGAGGGGTCCCAGAGCCAGCCGCGCCCG
CCCTCGCCCCCGGCCCCGCAGCCTTCCCGCCCTGCGCGCCATGAACGCCCCCGAGCGGCA
GCCCCAACCCGACGGCGGGGACGCCCCAGGCCACGAGCCTGGGGGCAGCCCCCAAGACGA
GCTTGACTTCTCCATCCTCTTCGACTATGAGTATTTGAATCCGAACGAAGAAGAGCCGAA
TGCACATAAGGTCGCCAGCCCACCCTCCGGACCCGCATACCCCGATGATGTCCTGGACTA
TGGCCTCAAGCCATACAGCCCCCTTGCTAGTCTCTCTGGCGAGCCCCCCGGCCGATTCGG
AGAGCCGGATAGGGTAGGGCCGCAGAAGTTTCTGAGCGCGGCCAAGCCAGCAGGGGCCTC
GGGCCTGAGCCCTCGGATCGAGATCACTCCGTCCCACGAACTGATCCAGGCAGTGGGGCC
CCTCCGCATGAGAGACGCGGGCCTCCTGGTGGAGCAGCCGCCCCTGGCCGGGGTGGCCGC
CAGCCCGAGGTTCACCCTGCCCGTGCCCGGCTTCGAGGGCTACCGCGAGCCGCTTTGCTT
GAGCCCCGCTAGCAGCGGCTCCTCTGCCAGCTTCATTTCTGACACCTTCTCCCCCTACAC
CTCGCCCTGCGTCTCGCCCAATAACGGCGGGCCCGACGACCTGTGTCCGCAGTTTCAAAA
CATCCCTGCTCATTATTCCCCCAGAACCTCGCCAATAATGTCACCTCGAACCAGCCTCGC
CGAGGACAGCTGCCTGGGCCGCCACTCGCCCGTGCCCCGTCCGGCCTCCCGCTCCTCATC
GCCTGGTGCCAAGCGGAGGCATTCGTGCGCCGAGGCCTTGGTTGCCCTGCCGCCCGGAGC
CTCACCCCAGCGCTCCCGGAGCCCCTCGCCGCAGCCCTCATCTCACGTGGCACCCCAGGA
CCACGGCTCCCCGGCTGGGTACCCCCCTGTGGCTGGCTCTGCCGTGATCATGGATGCCCT
GAACAGCCTCGCCACGGACTCGCCTTGTGGGATCCCCCCCAAGATGTGGAAGACCAGCCC
TGACCCCTCGCCGGTGTCTGCCGCCCCATCCAAGGCCGGCCTGCCTCGCCACATCTACCC
GGCCGTGGAGTTCCTGGGGCCCTGCGAGCAGGGCGAGAGGAGAAACTCGGCTCCAGAATC
CATCCTGCTGGTTCCGCCCACTTGGCCCAAGCCGCTGGTGCCTGCCATTCCCATCTGCAG
CATCCCAGTGACTGCATCCCTCCCTCCACTTGAGTGGCCGCTGTCCAGTCAGTCAGGCTC
TTACGAGCTGCGGATCGAGGTGCAGCCCAAGCCACATCACCGGGCCCACTATGAGACAGA
AGGCAGCCGAGGGGCTGTCAAAGCTCCAACTGGAGGCCACCCTGTGGTTCAGCTCCATGG
CTACATGGAAAACAAGCCTCTGGGACTTCAGATCTTCATTGGGACAGCTGATGAGCGGAT
CCTTAAGCCGCACGCCTTCTACCAGGTGCACCGAATCACGGGGAAAACTGTCACCACCAC
CAGCTATGAGAAGATAGTGGGCAACACCAAAGTCCTGGAGATACCCTTGGAGCCCAAAAA
CAACATGAGGGCAACCATCGACTGTGCGGGGATCTTGAAGCTTAGAAACGCCGACATTGA
GCTGCGGAAAGGCGAGACGGACATTGGAAGAAAGAACACGCGGGTGAGACTGGTTTTCCG
AGTTCACATCCCAGAGTCCAGTGGCAGAATCGTCTCTTTACAGACTGCATCTAACCCCAT
CGAGTGCTCCCAGCGATCTGCTCACGAGCTGCCCATGGTTGAAAGACAAGACACAGACAG
CTGCCTGGTCTATGGCGGCCAGCAAATGATCCTCACGGGGCAGAACTTTACATCCGAGTC
CAAAGTTGTGTTTACTGAGAAGACCACAGATGGACAGCAAATTTGGGAGATGGAAGCCAC
GGTGGATAAGGACAAGAGCCAGCCCAACATGCTTTTTGTTGAGATCCCTGAATATCGGAA
CAAGCATATCCGCACACCTGTAAAAGTGAACTTCTACGTCATCAATGGGAAGAGAAAACG
AAGTCAGCCTCAGCACTTTACCTACCACCCAGTCCCAGCCATCAAGACGGAGCCCACGGA
TGAATATGACCCCACTCTGATCTGCAGCCCCACCCATGGAGGCCTGGGGAGCCAGCCTTA
CTACCCCCAGCACCCGATGGTGGCCGAGTCCCCCTCCTGCCTCGTGGCCACCATGGCTCC
CTGCCAGCAGTTCCGCACGGGGCTCTCATCCCCTGACGCCCGCTACCAGCAACAGAACCC
AGCGGCCGTACTCTACCAGCGGAGCAAGAGCCTGAGCCCCAGCCTGCTGGGCTATCAGCA
GCCGGCCCTCATGGCCGCCCCGCTGTCCCTTGCGGACGCTCACCGCTCTGTGCTGGTGCA
CGCCGGCTCCCAGGGCCAGAGCTCAGCCCTGCTCCACCCCTCTCCGACCAACCAGCAGGC
CTCGCCTGTGATCCACTACTCACCCACCAACCAGCAGCTGCGCTGCGGAAGCCACCAGGA
GTTCCAGCACATCATGTACTGCGAGAATTTCGCACCAGGCACCACCAGACCTGGCCCGCC
CCCGGTCAGTCAAGGTCAGAGGCTGAGCCCGGGTTCCTACCCCACAGTCATTCAGCAGCA
GAATGCCACGAGCCAAAGAGCCGCCAAAAACGGACCCCCGGTCAGTGACCAAAAGGAAGT
ATTACCTGCGGGGGTGACCATTAAACAGGAGCAGAACTTGGACCAGACCTACTTGGATGA
TGTTAATGAAATTATCAGGAAGGAGTTTTCAGGACCTCCTGCCAGAAATCAGACGTAAAA
GAAGCCATTATAGCAAGACACCTTCTGTATCTGACCCCTCGGAGCCCTCCACAGCCCCTC
ACCTTCTGTCTCCTTTCATGTTCATCTCCCAGCCCGGAGTCCACACGCGGATCAATGTAT
GGGCACTAAGCGGACTCTCACTTAAGGAGCTCGCCACCTCCCTCTAAACACCAGAGAGAA
CTCTTCTTTTCGGTTTATGTTTTAAATCCCAGAGAGCATCCTGGTTGATCTTAATGGTGT
TCCGTCCAAATAGTAAGCACCTGCTGACCAAAAGCACATTCTACATGAGACAGGACACTG
GAACTCTCCTGAGAACAGAGTGACTGGAGCTTGGGGGGATGGACGGGGGACAGAAGATGT
GGGCACTGTGATTAAACCCCAGCCCTTGCGTTCGTTTTTCCAGGTCACAGATACAGCTCC
TGTACCTTTTGAAGGCAAGGAGTTCTCAGAGCAACCAAAGGAACGTGACCCAAGAGCCCA
GCTTACAGGCTGAAGAAACCCAAAACCCTCGATAGAGACAGAAACTGAACTGTCAGTCCT
TAGAGCTCGCCCAGTCCATGCCACAACTGGGCCACAGCTAAAGCTTTATTTTTGAATTCT
CATTCCAAAACCAAACTGTCTTGCCCAGACAAGATCACCTGTTAAGACTTCTTGGCGTTA
AGTTATGACATGTATACGCGTTTGTTATTATTATTTTTTCTGCTTTAAAAGGCTGACCAG
GGCACCTAGCCCTGGAGCTGTCTTGGCGAGCTGTTCTTTAACCCCTGCAGCACGCAGTCC
TGCTAACACAATTTCCATAGACTTGGGGGGCTGACCCAGGCTGCAGAGAGCAAGCACCTG
TCTGCTGCAGCTGTACAACCTGGATGCTTTGCAAGGTTCCGGCTTGCTTTCTTCCTAGCA
GCCAGAGTGCTTTTCCGTAAAGCGGTGGAGAATCTCAAGCATGTGCATTTAATTGAGGAA
TAGCAGAAGGGCTAAAGCAACCAAGAAAAGAAGTGTGGGTATTTTTGTTAAGTAAAACAG
CCCAAGTGCTTCTGGAGGTGGGTTTCTACCAAGATAGAGGAAAAGGGCTGAATTCCCTCT
AAGTGGGACAGCCGAGCTCAGGATGTGCTTCCCAGCTTCACTGGTTAATTTGACCTGAAC
CTATTTAAAGATCCCTTCTGCCCCTGAAGACCTATCCGCACTCAAATTCTAACATGAAGA
AATCTACTCGAATGCATCCTTTACTTTGAATGAGCTCTATTCGGTTGCATGTTATATGTG
ATTTCCTTCCTCCCAACTGTTTCCACTGAGCGCACCCACAGTCTCCCCTAGTCTTCCTCT
GTGGGTGTGATTTTTGTGATTTTTACAAACAAAACCCTTGAAGTTCTTGGCAGATGTGTT
TGTTTCTGTTTGCATGTACTGCAGATACCCCAGGACAAGCGGGGGATTCATTTTTCAGCC
ATTCAGTTGTTTCCTCAATAATCCGCAGCAAAGTGAAAATATTCTTAGCACTCAGACTGT
ACTTAGAGTGTTTTCTCAGTCCAGTCTGTACAGTCTGTAGGCAGAAGGCCTCAGAAGAAA
GTCATGGCCACTCAGTGCCCACTGTGGGCTTTGTAAGTCCTGGCTCTCCCGTCAAGGTTA
CCCAGAGGTAAAAGCTTCCTGGGAGTGGGGCCAGGTGTGTTTGGCACTCCAGATAGAAGG
CAAAATGCTCAGATTCGGGCCTGTGCACTTGTATGCAACCTGTCGGTCGATACCTAGCAT
TTATTTTTCCCTGACAATGAACGACCTTTCCCTCACCCACCCTAAGCTCAAAGAGTTTAG
CAAAATTCTCTTTTAAATAAACAGAATGCCAGTAAGAGGTTGACCCCTACCATGGAACTT
CTGGGATGCTAAATACTTCCTCATGAACAAAACAAGTTCCTTATTATAAGTTCCTTATAC
TAGCAGCTTCACCTAAAGAATTTTCTCTCCAGCAATATTGACTTCACTGGGGAAAAGCCA
AGAGTGTGTGGTGAGTGATTTGTTCTCACTCGACCTGGCTAGGACTGGCTAGGAGCTGTT
TTTTGTACATGAGGGAATTTGGGCTTTCCTCAGTTATCTGAATGTTTTACCCAAGTGCCT
TCCTGCTATTGTAGCAAAGTAGCTCAGCTTCCTTGTCCACAGGGTGAAAAAGGACTAATG
CATTTTCCATCAGTTTTCTAACTATGTTAGCAAAAAGGGCCTCCTGGTAGCTCAACCTCC
TGTACGCGTGTATGTGTGTAATACACACACAAATAAACCCCTCTGTTTTTCTAAGACATC
TTAGCTGGATATTATAGGAAGCACTTTCATAAACAACTGTAACAAATCGCAAAGGAAAGA
GAAACAAAAGCATTAGATTTGAGACATAAACAGGCAAGAGAAAGTGTATTAGGAACTGAC
AGCTATCAAGGAAGTTTTGTCAGTTACAAATGCTAGGAGGAAATTTTGCCAGGAAGGATG
GCTCATGAAATATTTCCAGTACGGGAAGAGGCAATAAGATCCTCTAAGAGAATGAGAAAG
TAGGGGTGTCTAAATGGTAAAGATGGGTGTGTTGCACGTGTGTTAGAAGGATCTCAGTTG
AGTGAAGGTTTGCACTGCTACATCTAAGTTAATGTAAATATGTAGCACTCTGACAGGTCT
ACCGTGTTGCTGAATGTAGTATATTTCCAAAGTTTGCAAGTCTTCCTGTATTGTACAAAG
ATGCTGCTGCTTGATAATATGTATAGCAATCCAGATTAGTATGTTATTAAATTTTATTTT
CTTACCTGTATTTTTATGCTTTTTACCTGTCCTCAAAATATTACACCCCTGTTGGAATTA
GATTTATATTTATAAATGGTCAGAAATCTTTTTAAGTGTCTCTTTTTACACATAGGTTGA
TTTTTTTTTTCTTAAGAGAAATGATGTATTCTTGAAACATTTGTTACTCATTCCAGGAAA
CAAAAACCCATATAATAAAACCCCCACTCAGAGCCTGTTAGTCACCTCTCTAGAAGATGG
CATCTCAGGAGAAGGAATGGCTTTGTGGAAGAAGGAATCACCTTTTTCTTGCTCAAGAAT
TATGCTGACTTCAGCCCTGAGCCTGGATCTGGTCACTGAGAATCATCAAGTGTCTAGATC
CTCCCCCCAAAATAACTAATTTAGTAGGTGATTTTGATTTTAAAAAATTGACACCAAAAC
CCTGCCTGCATTGTAATGGAATTCGAAAAGAATTCATGTTCACAGAACTCAACGTTCAGG
CTAATATTTACAGAAGGGACCAAATCTAAATCCTGGTAGATAACTCCTGTATGCTTTATC
CAAAGGACACCCACAGTTTTCCAGCATAGATATAACCAAGGATGAATTGATTCCTTCAAA
GAACTGGGAGGCACGGATATTGCATTTTTTGTTTACATCCAGTAGCCAAGACGCCTCAGT
GAGCCAGTCTTGGGCAGAGGCTGTCACATTTAGGCAGATTGGAAGTTGGTATGTTCTAAT
TCTCACTCTGGACTACAGTGAGGCTGAATTTATCATGTCAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_173091
Insert Size 3100 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_173091.2, NP_775114.1
RefSeq Size 3166 bp
RefSeq ORF 2778 bp
Locus ID 4773
Cytogenetics 20q13.2
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
Gene Summary 'This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]'
Transcript Variant: This variant (2) encodes the longest isoform (C). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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