IL1RA (IL1RN) (NM_173842) Human Untagged Clone
CAT#: SC306939
IL1RN (untagged)-Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1
"NM_173842" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | IL1RN |
Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_173842 edited
ATGGAAATCTGCAGAGGCCTCCGCAGTCACCTAATCACTCTCCTCCTCTTCCTGTTCCAT TCAGAGACGATCTGCCGACCCTCTGGGAGAAAATCCAGCAAGATGCAAGCCTTCAGAATC TGGGATGTTAACCAGAAGACCTTCTATCTGAGGAACAACCAACTAGTTGCCGGATACTTG CAAGGACCAAATGTCAATTTAGAAGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCT CTGTTCTTGGGAATCCATGGAGGGAAGATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAG ACCAGACTCCAGCTGGAGGCAGTTAACATCACTGACCTGAGCGAGAACAGAAAGCAGGAC AAGCGCTTCGCCTTCATCCGCTCAGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCC TGCCCCGGTTGGTTCCTCTGCACAGCGATGGAAGCTGACCAGCCCGTCAGCCTCACCAAT ATGCCTGACGAAGGCGTCATGGTCACCAAATTCTACTTCCAGGAGGACGAGTAG >OriGene 5' read for NM_173842 unedited
TTGTNACGTCGTTTTTTGTATACGACTCCTATAGGCGGCCGCGNAATTCTGGNAAATCTG CAGAGGCCTCCGCAGTCACCTAATCACTCTCCTCCTCTTCCTGTTCCATTCAGAGACGAT CTGCCGACCCTCTGGGAGAAAATCCAGCAAGATGCAAGCCTTCAGAATCTGGGATGTTAA CCAGAAGACCTTCTATCTGAGGAACAACCAACTAGTTGCCGGATACTTGCAAGGACCAAA TGTCAATTTAGAAGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGG AATCCATGGAGGGAAGATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCA GCTGGAGGCAGTTAACATCACTGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGC CTTCATCCGCTCAGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTG GTTCCTCTGCACAGCGATGGAAGCTGACCAGCCCGTCAGCCTCACCAATATGCCTGACGA AGGCGTCATGGTCACCAAATTCTACTTCCAGGAGGACGAGTAGTACTGCCCAGGCCTGCC TGTTCCCATTCTTGCATGGCAAGGACTGCAGGNACTGCCAGTCCCCCTGCCCCAGGGCTC CCGGCTATGGGGGCACTNGAGACCAGCCATTGAGGGGTGGACCCTCAGAAGGCGTCACAA CAACCTGGTCACAGGACTCTGCCTTCTCTTCACTGACCAGCCTCCATGCTGCCTNCAGAA TGGTCTTTCTAATGTGTGAAATCAGAACACAGGAGCCCCTGCACCAAGCCCTTCCATGTC CGCCCCTGCTTTCAGGGATCAAACCCCGACCACCT |
Restriction Sites | Please inquire |
ACCN | NM_173842 |
Insert Size | 2000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_173842.1, NP_776214.1 |
RefSeq Size | 1760 bp |
RefSeq ORF | 534 bp |
Locus ID | 3557 |
Cytogenetics | 2q14.1 |
Protein Families | Druggable Genome, Secreted Protein |
Gene Summary | 'The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]' Transcript Variant: This variant (1) differs in the 5' end compared to variant 2, resulting in an isoform (1) that has a distinct and shorter N-terminus, as compared to the longest isoform (2). |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC218518 | IL1RN (Myc-DDK-tagged)-Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
USD 420.00 |
|
RG218518 | IL1RN (GFP-tagged) - Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
USD 460.00 |
|
RC218518L1 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
|
RC218518L2 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC218518L3 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, Myc-DDK-tagged |
USD 620.00 |
|
RC218518L4 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, mGFP tagged |
USD 620.00 |
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