AGO3 (NM_177422) Human Untagged Clone

CAT#: SC307093

AGO3 (untagged)-Human eukaryotic translation initiation factor 2C, 3 (EIF2C3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AGO3
• Synonyms: EIF2C3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_177422, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGTGAAGTTCTTGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAA
  AATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCATTGTGGAACAATGAGACGGAAATACCG
  TGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGCCAAACT
  GTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCT
  GTCTGCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCA
  ACGATGTATCAAGAAGCTAACAGACAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCA
  GATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGATCCATTTGTTCAGGAGT
  TTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTA
  TGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCAC
  ACAGGAGTTGAAATCAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATAT
  TGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATG
  CTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACATATTCT
  GGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAG
  ACACACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCT
  GTCAAACTTGTGCCTAAAGATAAATGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGA
  CCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCACCTGCTGGTGATGGAA
  AGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAG
  AGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTT
  TATAAGTCAACTCGGTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTA
  GGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACC
  TGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACAGAAAGG
  GTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCG
  ATTTTTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGA
  TGATAACTGCTTTACTGCAGATGAACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGT
  ACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGAGCCAGATATCATC
  TTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACA
  AGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_177422
• ORF Size: 1881 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_177422.2, NP_803171.1
• RefSeq Size: 3409
• RefSeq ORF: 1881
• Locus ID: 192669
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) has multiple differences in the coding region, which causes translation initiation at a downstream start codon, compared to variant 1. The resulting protein (isoform b) has a shorter N-terminus than isoform a.