BRCC45 (BRE) (NM_199193) Human Untagged Clone

CAT#: SC307898

BRE (untagged)-Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BABAM2
• Synonyms: BRCC4; BRCC45; BRE
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_199193, the custom clone sequence may differ by one or more nucleotides
  ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGC
  GTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTA
  AAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
  CCATATGCTGGAGAGACATTAAAGTGGGATATCATTTTCAATGCCCAATACCCAGAACTG
  CCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTTGCAG
  AATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTT
  GTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTT
  GAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGG
  AAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGAT
  TTCAGCAATATCCCCACATACCTTCTCAAGGATGTAAATGAAGACCCTGGAGAAGATGTG
  GCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCTGTAC
  TTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTT
  CCAGGAGGAGGATGTCTCATTGATTACGTTCCTCAAGTATGCCACCTGCTCACCAACAAG
  GTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCTCAGT
  CACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTG
  CTGATGTGGAAAGATTTTTGTTTTCTTGTACACATTGACCTGCCTCTGTTTTTCCCTCGA
  GACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCTTTAC
  TCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAA
  AGAGCAAAAAGAGAGAGCAACAGAGATGGGGAGGAATCCAGCTCTGCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_199193
• ORF Size: 1131 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_199193.1, NP_954663.1
• RefSeq Size: 1932
• RefSeq ORF: 1131
• Locus ID: 9577
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]