SOCS4 (NM_199421) Human Untagged Clone

CAT#: SC307967

SOCS4 (untagged)-Human suppressor of cytokine signaling 4 (SOCS4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOCS4
• Synonyms: SOCS7
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_199421, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGAAAATAATGAAAATATTAGTAAAAATGTAGATGTAAGGCCCAAAACTAGTCGGAGCAGAAGTG
  CCGACAGAAAAGACGGTTATGTGTGGAGTGGAAAGAAGTTATCTTGGTCAAAAAAGAGTGAGAGTTATTC
  AGATGCTGAGACAGTGAATGGTATAGAGAAAACCGAAGTGTCTTTAAGGAACCAAGAAAGGAAGCACAGC
  TGTTCATCCATTGAGTTGGACTTAGATCATTCCTGTGGGCATCGATTTTTAGGCCGATCTCTTAAACAGA
  AACTGCAAGATGCCGTGGGGCAGTGTTTTCCAATAAAGAATTGTAGTAGTCGGCACTCTTCAGGGCTTCC
  GTCTAAAAGGAAAATTCATATCAGTGAACTCATGTTAGATAAGTGTCCTTTCCCACCTCGATCAGATTTA
  GCCTTTAGGTGGCATTTTATTAAACGACACACTGCTCCTATAAATTCCAAATCAGATGAATGGGTAAGCA
  CAGACTTGTCTCAGACTGAATTGAGGGATGGTCAGCTAAAACGAAGAAATATGGAAGAAAATATAAACTG
  TTTCTCACATACCAATGTTCAGCCCTGTGTCATAACCACCGACAATGCTTTGTGTAGAGAAGGTCCTATG
  ACTGGCTCTGTGATGAACCTGGTTTCAAATAACAGTATAGAAGATAGTGATATGGATTCCGATGATGAAA
  TTCTAACACTTTGCACAAGTTCCAGAAAAAGAAACAAACCCAAATGGGATTTGGATGATGAAATCCTGCA
  GTTGGAAACACCTCCTAAATACCACACGCAGATTGATTATGTCCACTGTCTTGTACCAGACCTCCTTCAG
  ATCAATAACAACCCATGTTACTGGGGAGTGATGGATAAATACGCAGCCGAAGCACTACTGGAAGGAAAAC
  CAGAGGGTACCTTTTTACTTCGAGACTCAGCACAGGAAGACTATTTATTCTCTGTTAGTTTTAGACGCTA
  TAGTCGTTCTCTTCATGCTAGAATTGAACAGTGGAATCACAACTTTAGCTTTGATGCACATGACCCCTGT
  GTCTTCCATTCTCCTGACATTACTGGGCTCCTAGAACATTATAAGGACCCAAGCGCCTGTATGTTCTTTG
  AACCACTTCTATCCACTCCCTTAATTCGGACTTTCCCTTTTTCCCTGCAGCATATATGCAGAACAGTTAT
  TTGTAACTGTACAACTTATGATGGCATCGATGCCCTTCCAATTCCTTCTTCTATGAAATTATATCTGAAG
  GAATATCATTATAAATCAAAAGTTAGAGTACTCAGGATTGATGCACCAGAACAGCAATGCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_199421
• ORF Size: 1323 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_199421.1, NP_955453.1
• RefSeq Size: 7029
• RefSeq ORF: 1323
• Locus ID: 122809
• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
• Gene Summary: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) is the longer transcript and it has an additional exon in the 5' region.