FOXO3 (NM_201559) Human Untagged Clone

CAT#: SC308058

FOXO3 (untagged)-Human forkhead box O3 (FOXO3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXO3
• Synonyms: AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_201559 edited
  GCGCGAGGCCGTCGATTCGCTCGCGGCTCCATCGCGGCCTGGCCGGGGGGCGGTGTCTGC
  TGCGCCAGGTTCGCTGGCCGCACGTCTTCAGGTCCTCCTGTTCCTGGGAGGCGGGCGCGG
  CAGGACTGGGAGGTGGCGGCAGCGGGCGAGGACTCGCCGAGGACGGGGCTCCGGCCCGGG
  ATAACCAACTCTCCTTCTCTCTTCTTTGGTGCTTCCCCAGGCGGCGGCGGCGGCGCCCGG
  GAGCCGGAGCCTTCGCGGCGTCCACGTCCCTCCCCCGCTGCACCCCGCCCCGGCGCGAGA
  GGAGAGCGCGAGAGCCCCAGCCGCGGGCGGGCGGGCGGCGAAGATGGCAGAGGCACCGGC
  TTCCCCGGCCCCGCTCTCTCCGCTCGAAGTGGAGCTGGACCCGGAGTTCGAGCCCCAGAG
  CCGTCCGCGATCCTGTACGTGGCCCCTGCAAAGGCCGGAGCTCCAAGCGAGCCCTGCCAA
  GCCCTCGGGGGAGACGGCCGCTGACTCCATGATCCCCGAGGAGGAGGACGATGAAGACGA
  CGAGGACGGCGGGGGACGGGCCGGCTCGGCCATGGCGATCGGCGGCGGCGGCGGGAGCGG
  CACGCTGGGCTCCGGGCTGCTCCTTGAGGACTCGGCCCGGGTGCTGGCACCCGGAGGGCA
  AGACCCCGGGTCTGGGCCAGCCACCGCGGCGGGCGGGCTGAGCGGGGGTACACAGGCGCT
  GCTGCAGCCTCAGCAACCGCTGCCACCGCCGCAGCCGGGGGCGGCTGGGGGCTCCGGGCA
  GCCGAGGAAATGTTCGTCGCGGCGGAACGCCTGGGGAAACCTGTCCTACGCGGACCTGAT
  CACCCGCGCCATCGAGAGCTCCCCGGACAAACGGCTCACTCTGTCCCAGATCTACGAGTG
  GATGGTGCGTTGCGTGCCCTACTTCAAGGATAAGGGCGACAGCAACAGCTCTGCCGGCTG
  GAAGAACTCCATCCGGCACAACCTGTCACTGCATAGTCGATTCATGCGGGTCCAGAATGA
  GGGAACTGGCAAGAGCTCTTGGTGGATCATCAACCCTGATGGGGGGAAGAGCGGAAAAGC
  CCCCCGGCGGCGGGCTGTCTCCATGGACAATAGCAACAAGTATACCAAGAGCCGTGGCCG
  CGCAGCCAAGAAGAAGGCAGCCCTGCAGACAGCCCCCGAATCAGCTGACGACAGTCCCTC
  CCAGCTCTCCAAGTGGCCTGGCAGCCCCACGTCACGCAGCAGTGATGAGCTGGATGCGTG
  GACGGACTTCCGTTCACGCACCAATTCTAACGCCAGCACAGTCAGTGGCCGCCTGTCGCC
  CATCATGGCAAGCACAGAGTTGGATGAAGTCCAGGACGATGATGCGCCTCTCTCGCCCAT
  GCTCTACAGCAGCTCAGCCAGCCTGTCACCTTCAGTAAGCAAGCCGTGCACGGTGGAACT
  GCCACGGCTGACTGATATGGCAGGCACCATGAATCTGAATGATGGGCTGACTGAAAACCT
  CATGGACGACCTGCTGGATAACATCACGCTCCCGCCATCCCAGCCATCGCCCACTGGGGG
  ACTCATGCAGCGGAGCTCTAGCTTCCCGTATACCACCAAGGGCTCGGGCCTGGGCTCCCC
  AACCAGCTCCTTTAACAGCACGGTGTTCGGACCTTCATCTCTGAACTCCCTACGCCAGTC
  TCCCATGCAGACCATCCAAGAGAACAAGCCAGCTACCTTCTCTTCCATGTCACACTATGG
  TAACCAGACACTCCAGGACCTGCTCACTTCGGACTCACTTAGCCACAGCGATGTCATGAT
  GACACAGTCGGACCCCTTGATGTCTCAGGCCAGCACCGCTGTGTCTGCCCAGAATTCCCG
  CCGGAACGTGATGCTTCGCAATGATCCGATGATGTCCTTTGCTGCCCAGCCTAACCAGGG
  AAGTTTGGTCAATCAGAACTTGCTCCACCACCAGCACCAAACCCAGGGCGCTCTTGGTGG
  CAGCCGTGCCTTGTCGAATTCTGTCAGCAACATGGGCTTGAGTGAGTCCAGCAGCCTTGG
  GTCAGCCAAACACCAGCAGCAGTCTCCTGTCAGCCAGTCTATGCAAACCCTCTCGGACTC
  TCTCTCAGGCTCCTCCTTGTACTCAACTAGTGCAAACCTGCCCGTCATGGGCCATGAGAA
  GTTCCCCAGCGACTTGGACCTGGACATGTTCAATGGGAGCTTGGAATGTGACATGGAGTC
  CATTATCCGTAGTGAACTCATGGATGCTGATGGGTTGGATTTTAACTTTGATTCCCTCAT
  CTCCACACAGAATGTTGTTGGTTTGAACGTGGGGAACTTCACTGGTGCTAAGCAGGCCTC
  ATCTCAGAGCTGGGTGCCAGGCTGAAGGATCACTGAGGAAGGGGAAGTGGGCAAAGCAGA
  CCCTCAAACTGACACAAGACCTACAGAGAAAACCCTTTGCCAAATCTGCTCTCAGCAAGT
  GGACAGTGATACCGTTTACAGCTTAACACCTTTGTGAATCCCACGCCATTTTCCTAACCC
  AGCAGAGACTGTTAATGGCCCCTTACCCTGGGTGAAGCACTTACCCTTGGAACAGAACTC
  TAAAAAGTATGCAAAATCTTCCTTGTACAGGGTGGTGAGCCGCCTGCCAGTGGAGGACAG
  CACCCCTCAGCACCACCCACCCTCATTCAGAGCACACCGTGAGCCCCCGTCGGCCATTCT
  GTGGTGTTTTAATATTGCGATGGTTTATGGGACGTTTTAAGTGTTGTTCTTGTGTTTGTT
  TTCCTTTGACTTTCTGAGTTTTTCACATGCATTAACTTGCGGTATTTTTCTGTTAAAATG
  TTAACCGTCCTTCCCCTAGCAAATTTAAAAACAGAAAGAAAATGTTGTACCAGTTACCAT
  TCCGGGTTCGAGCATCACAAGCTTTTGAGCGCATGGAACTCCATAAACTAACAAATTACA
  TAAACTAAAGGGGGATTTTCTTTCTTCTTTTGTTTGGTAGAAAATTATCCTTTTCTAAAA
  ACTGAACAATGGCACAATTGTTTGCTATGTGCACCCGTCCAGGACAGAACCGTGCATAGG
  CAAAAGGAGTGGAGCACAGCGTCCGGCCCAGTGTGTTTCCGGTTCTGAGTCAGGGTGATC
  TGTGGACGGGACCCCAGCACCAAGTCTACGGGTGCCAGATCAGTAGGGCCTGTGATTTCC
  TGTCAGTGTCCTCAGCTAATGTGAACAGTGTTGGTCTGCTGGTTAGAAACTAGAATATTG
  ATATTTTCAGGAAAGAAATCAGCTCAGCTCTCCACTCATTGCCAAATGTCACTAAAGGGT
  TTAGTTTTAAGGAGAAAGAAAAGGAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_201559
• Insert Size: 3300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_201559.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201559.1, NP_963853.1
• RefSeq Size: 3311 bp
• RefSeq ORF: 2022 bp
• Locus ID: 2309
• Cytogenetics: 6q21
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer
• Gene Summary: 'This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) differs in the 5' end compared to variant 1. Both variants encode the same protein.