Thromboxane A2 receptor (TBXA2R) (NM_201636) Human Untagged Clone

CAT#: SC308081

TBXA2R (untagged)-Human thromboxane A2 receptor (TBXA2R), transcript variant b

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TBXA2R
• Synonyms: BDPLT13; TXA2-R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_201636 edited
  CGGCCCCCACCCGTCCCAGCTCGGCTTAGCCCCCGCGGACCCCTCCAGGCCGCGACCCCA
  GGGCGTCCTGTGCCGCCACGCCCTCCATCTGTGTGGGTCCTCTGCTGGGCCCGCCCCTGG
  TCACAGCCAGACTGACTCAGTTTCCCTGGGAGGTCCCGCTCGAGCCCGTCCTTCCCCTCC
  CTCTGCCCGCCCCCAGCCCTCGCCCCACCCTCGGCGCCCGCACATCTGCCTGCTCAGCTC
  CAGACGGCGCCCGGACCCCCGGGCGCGGGATCCAGCCAGGTGGGAGCCCCGCAGATGAGG
  TCTCTGAAGGTGTGCCTGAACCAGTGCCAGCCTGCCCTGTCTGCAGCATCGGCCTGATGG
  GGTGGTGACTGATCCCTCAGGGCTCCGGAGCCATGTGGCCCAACGGCAGTTCCCTGGGGC
  CCTGTTTCCGGCCCACAAACATTACCCTGGAGGAGAGACGGCTGATCGCCTCGCCCTGGT
  TCGCCGCCTCCTTCTGCGTGGTGGGCCTGGCCTCCAACCTGCTGGCCCTGAGCGTGCTGG
  CGGGCGCGCGGCAGGGGGGTTCGCACACGCGCTCCTCCTTCCTCACCTTCCTCTGCGGCC
  TCGTCCTCACCGACTTCCTGGGGCTGCTGGTGACCGGTACCATCGTGGTGTCCCAGCACG
  CCGCGCTCTTCGAGTGGCACTCCGTGGACCCTGGCTGCCGTCTCTGTCGCTTCATGGGCG
  TCGTCATGATCTTCTTCGGCCTGTCCCCGCTGCTGCTGGGGGCCGCCATGGCCTCAGAGC
  GCTACCTGGGTATCACCCGGCCCTTCTCGCGCCCGGCGGTCGCCTCGCAGCGCCGCGCCT
  GGGCCACCGTGGGGCTGGTGTGGGCGGCCGCGCTGGCGCTGGGCCTGCTGCCCCTGCTGG
  GCGTGGGTCGCTACACCGTGCAATACCCGGGGTCCTGGTGCTTCCTGACGCTGGGCGCCG
  AGTCCGGGGACGTGGCCTTCGGGCTGCTCTTCTCCATGCTGGGCGGCCTCTCGGTCGGGC
  TGTCCTTCCTGCTGAACACGGTCAGCGTGGCCACCCTGTGCCACGTCTACCACGGGCAGG
  AGGCGGCCCAGCAGCGTCCCCGGGACTCCGAGGTGGAGATGATGGCTCAGCTCCTGGGGA
  TCATGGTGGTGGCCAGCGTGTGTTGGCTGCCCCTTCTGGTCTTCATTGCCCAGACAGTGC
  TGCGAAACCCGCCTGCCATGAGCCCCGCCGGGCAGCTGTCCCGCACCACGGAGAAGGAGC
  TGCTCATCTACTTGCGCGTGGCCACCTGGAACCAGATCCTGGACCCCTGGGTGTATATCC
  TGTTCCGCCGCGCCGTGCTCCGGCGTCTCCAGCCTCGCCTCAGCACCCGGCCCAG:CGGA
  GTCTCACTCTGTGGCCCAGCCTGGAGTACAGTGGCACGATCTCGGCTCACTGCAACCTCC
  GCCTCCCGGGTTCAAGCGATTCTCGTGCCTCAGCCTCCCGAGCAGCTGGGATTACAGGCG
  TAAGCCACTGCGCCCGGCCTTGCATGCTCTTTGACCCTGAATTTGACCTACTTGCTGGGG
  TACAGTTGCTTCCTTTTGAACCTCCAACAGGGAAGGCTCTGTCCAGAAAGGATTGAATGT
  GAACGGGGGCACCCCCTTTTCTTGCCAAAATATATCTCTGCCTTTGGTTTTATTTTAAAA
  AAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_201636 unedited
  AGGTCAGATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCGGCCCCCA
  CCCGTCCCAGCTCGGCTTAGCCCCCGCGGACCCCTCCAGGCCGCGACCCCAGGGCGTCCT
  GTGCCGCCACGCCCTCCATCTGTGTGGGTCCTCTGCTGGGCCCGCCCCTGGTCACAGCCA
  GACTGACTCAGTTTCCCTGGGAGGTCCCGCTCGAGCCCGTCCTTCCCCTCCCTCTGCCCG
  CCCCCAGCCCTCGCCCCACCCTCGGCGCCCGCACATCTGCCTGCTCAGCTCCAGACGGCG
  CCCGGACCCCCGGGCGCGGGATCCAGCCAGGTGGGAGCCCCGCAGATGAGGTCTCTGAAG
  GTGTGCCTGAACCAGTGCCAGCCTGCCCTGTCTGCAGCATCGGCCTGATGGGGTGGTGAC
  TGATCCCTCAGGGCTCCGGAGCCATGTGGCCCAACGGCAGTTCCCTGGGGCCCTGTTTCC
  GGCCCACAAACATTACCCTGGAGGAGAGACGGCTGATCGCCTCGCCCTGGTTCGCCGCCT
  CCTTCTGCGTGGTGGGCCTGGCCTCCAACCTGCTGGCCCTGAGCGTGCTGGCGGGCGCGC
  GGCAGGGGGGTTCGCACACGCGCTCCTCCTTCCTCACCTTCCTCTGCGGCCTCGTCCTCA
  CCGACTTCCTGGGGCTGCTGGTGACCGGTACCATCGTGGTGTCCCAGCACGCCGCGCTCT
  TCGAGTGGCACTCCGTGGACCCTGGCTGCCGTCTCTGTCGCTTCATGGGCGTCGTCATGA
  TCTTCTTCGGCCTGTCCCCGCTGCTGCTGGGGCCGCCATGGCCTCAAAGCGCTACCTGGG
  TATCACCCGGGCCTTCTCGCGCCCCGCGGTCGCCTCGCAACGCCGCGCCTGGGCACCGTG
  GG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_201636 unedited
  ACNGNNNANAAGTGCTGCGAAACCCGCCTGCCATGAGCCCCGCCGGGCAGCTGTCCCGCA
  CCACGGAGAAGGAGCTGCTCATCTACTTGCGCGTGGCCACCTGGAACCAGATCCTGGACC
  CCTGGGTGTATATCCTGTTCCGCCGCGCCGTGCTCCGGCGTCTCCAGCCTCGCCTCAGCA
  CCCGGCCCAGCGGAGTCTCACTCTGTGGCCCAGCCTGGAGTACAGTGGCACGATCTCGGC
  TCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCGTGCCTCAGCCTCCCGAGCAGC
  TGGGATTACAGGCGTAAGCCACTGCGCCCGGCCTTGCATGCTCTTTGACCCTGAATTTGA
  CCTACTTGCTGGGGTACAGTTGCTTCCTTTTGAACCTCCAACAGGGAAGGCTCTGTCCAG
  AAAGGATTGAATGTGAACGGGGGCACCCCCTTTTCTTGCCAAAATATATCTCTGCCTTTG
  GTTTTATTTTAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAG
  CTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGG
  CCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCA
  TTTTGTCTGACTAGGTGTCCTTCTATAATATTATGGGGTGGAGGGGGGTGGTATGGAGCA
  AAGGGCAAGTTGGGAAGACACCTGTAGGGCCTGCGGGGTCTATTGGGAACCAAGCTGGAG
  TGCAGTGGCACAATCTTGGTCACTGCAATCTCCCGCTCCTGGGTTAAGCGATTCTCCTGC
  CTAAGCCTCCCGAGTTGGTTGGGATCCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_201636
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_201636.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201636.1, NP_963998.1
• RefSeq Size: 1785 bp
• RefSeq ORF: 1110 bp
• Locus ID: 6915
• Cytogenetics: 19p13.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]'
  Transcript Variant: This variant (b) uses an alternate splice pattern in the 3' coding region, compared to variant a. The resulting isoform (beta) has a longer and distinct C-terminus, compared to isoform alpha. This isoform is described in PMID: 8613548.