PDLIM7 (NM_203352) Human Untagged Clone

CAT#: SC308131

PDLIM7 (untagged)-Human PDZ and LIM domain 7 (enigma) (PDLIM7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDLIM7
• Synonyms: LMP1; LMP3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_203352, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGACT
  TCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAGGCCGGAGTGGCCGTGGG
  TGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAACAAGATC
  CGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGG
  TGCAGACCCCTGACAAACAGCCGCTCCGACCGCTGGTCCCAGATGCCAGCAAGCAGCGGCTGATGGAGAA
  CACAGAGGACTGGCGGCCGCGGCCGGGGACAGGCCAGTCGCGTTCCTTCCGCATCCTTGCCCACCTCACA
  GGCACCGAGTTCATGCAAGACCCGGATGAGGAGCACCTGAAGAAATCAAGCCAGGTGCCCAGGACAGAAG
  CCCCAGCCCCAGCCTCATCTACACCCCAGGAGCCCTGGCCTGGCCCTACCGCCCCCAGCCCTACCAGCCG
  CCCGCCCTGGGCTGTGGACCCTGCGTTTGCCGAGCGCTATGCCCCGGACAAAACGAGCACAGTGCTGACC
  CGGCACAGCCAGCCGGCCACGCCCACGCCGCTGCAGAGCCGCACCTCCATTGTGCAGGCAGCTGCCGGAG
  GGGTGCCAGGAGGGGGCAGCAACAACGGCAAGACTCCCGTGTGTCACCAGTGCCACAAGGTCATCCGGGG
  CCGCTACCTGGTGGCGCTGGGCCACGCGTACCACCCGGAGGAGTTTGTGTGTAGCCAGTGTGGGAAGGTC
  CTGGAAGAGGGTGGCTTCTTTGAGGAGAAGGGCGCCATCTTCTGCCCACCATGCTATGACGTGCGCTATG
  CACCCAGCTGTGCCAAGTGCAAGAAGAAGATTACAGGCGAGATCATGCACGCCCTGAAGATGACCTGGCA
  CGTGCACTGCTTTACCTGTGCTGCCTGCAAGACGCCCATCCGGAACAGGGCCTTCTACATGGAGGAGGGC
  GTGCCCTATTGCGAGCGAGACTATGAGAAGATGTTTGGCACGAAATGCCATGGCTGTGACTTCAAGATCG
  ACGCTGGGGACCGCTTCCTGGAGGCCCTGGGCTTCAGCTGGCATGACACCTGCTTCGTCTGTGCGATATG
  TCAGATCAACCTGGAAGGAAAGACCTTCTACTCCAAGAAGGACAGGCCTCTCTGCAAGAGCCATGCCTTC
  TCTCATGTGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_203352
• ORF Size: 1272 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_203352.2, NP_976227.1
• RefSeq Size: 1668
• RefSeq ORF: 1272
• Locus ID: 9260
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 2 which is shorter than isoform 1.