NLRP7 (NM_206828) Human Untagged Clone

CAT#: SC308273

NLRP7 (untagged)-Human NLR family, pyrin domain containing 7 (NLRP7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP7
• Synonyms: CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_206828, the custom clone sequence may differ by one or more nucleotides
  ATGACATCGCCCCAGCTAGAGTGGACTCTGCAGACCCTTCTGGAGCAGCTGAACGAGGAT
  GAATTAAAGAGTTTCAAATCCCTTTTATGGGCTTTTCCCCTCGAAGACGTGCTACAGAAG
  ACCCCATGGTCTGAGGTGGAAGAGGCTGATGGCAAGAAACTGGCAGAAATTCTGGTCAAC
  ACCTCCTCAGAAAATTGGATAAGGAATGCGACTGTGAACATCTTGGAAGAGATGAATCTC
  ACGGAATTGTGTAAGATGGCAAAGGCTGAGATGATGGAGGACGGACAGGTGCAAGAAATA
  GATAATCCTGAGCTGGGAGATGCAGAAGAAGACTCGGAGTTAGCAAAGCCAGGTGAAAAG
  GAAGGATGGAGAAATTCAATGGAGAAACAGTCTTTGGTCTGGAAGAACACCTTTTGGCAA
  GGAGACATTGACAATTTCCATGACGACGTCACTCTGAGAAACCAACGGTTCATTCCATTC
  TTGAATCCCAGAACACCCAGGAAGCTAACACCTTACACGGTGGTGCTGCACGGCCCCGCA
  GGCGTGGGGAAAACCACGCTGGCCAAAAAGTGTATGCTGGACTGGACAGACTGCAACCTC
  AGCCCGACGCTCAGATACGCGTTCTACCTCAGCTGCAAGGAGCTCAGCCGCATGGGCCCC
  TGCAGTTTTGCAGAGCTGATCTCCAAAGACTGGCCTGAATTGCAGGATGACATTCCAAGC
  ATCCTAGCCCAAGCACAGAGAATCCTGTTCGTGGTCGATGGCCTTGATGAGCTGAAAGTC
  CCACCTGGGGCGCTGATCCAGGACATCTGCGGGGACTGGGAGAAGAAGAAGCCGGTGCCC
  GTCCTCCTGGGGAGTTTGCTGAAGAGGAAGATGTTACCCAGGGCAGCCTTGCTGGTCACC
  ACGCGGCCCAGGGCACTGAGGGACCTCCAGCTCCTGGCGCAGCAGCCGATCTACGTAAGG
  GTGGAGGGCTTCCTGGAGGAGGACAGGAGGGCCTATTTCCTGAGACACTTTGGAGACGAG
  GACCAAGCCATGCGTGCCTTTGAGCTAATGAGGAGCAACGCGGCCCTGTTCCAGCTGGGC
  TCGGCCCCCGCGGTGTGCTGGATTGTGTGCACGACTCTGAAGCTGCAGATGGAGAAGGGG
  GAGGACCCGGTCCCCACCTGCCTCACCCGCACGGGGCTGTTCCTGCGTTTCCTCTGCAGC
  CGGTTCCCGCAGGGCGCACAGCTGCGGGGCGCGCTGCGGACGCTGAGCCTCCTGGCCGCG
  CAGGGCCTGTGGGCGCAGATGTCCGTGTTCCACCGAGAGGACCTGGAAAGGCTCGGGGTG
  CAGGAGTCCGACCTCCGTCTGTTCCTGGACGGAGACATCCTCCGCCAGGACAGAGTCTCC
  AAAGGCTGCTACTCCTTCATCCACCTCAGCTTCCAGCAGTTTCTCACTGCCCTGTTCTAC
  GCCCTGGAGAAGGAGGAGGGGGAGGACAGGGACGGCCACGCCTGGGACATCGGGGACGTA
  CAGAAGCTGCTTTCCGGAGAAGAAAGACTCAAGAACCCCGACCTGATTCAAGTAGGACAC
  TTCTTATTCGGCCTCGCTAACGAGAAGAGAGCCAAGGAGTTGGAGGCCACTTTTGGCTGC
  CGGATGTCACCGGACATCAAACAGGAATTGCTGCAATGCAAAGCACATCTTCATGCAAAT
  AAGCCCTTATCCGTGACCGACCTGAAGGAGGTCTTGGGCTGCCTGTATGAGTCTCAGGAG
  GAGGAGCTGGCGAAGGTGGTGGTGGCCCCGTTCAAGGAAATTTCTATTCACCTGACAAAT
  ACTTCTGAAGTGATGCATTGTTCCTTCAGCCTGAAGCATTGTCAAGACTTGCAGAAACTC
  TCACTGCAGGTAGCAAAGGGGGTGTTCCTGGAGAATTACATGGATTTTGAACTGGACATT
  GAATTTGAAAGGTGCACTTACCTAACCATTCCGAACTGGGCTCGGCAGGATCTTCGCTCT
  CTTCGCCTCTGGACAGATTTCTGCTCTCTCTTCAGCTCAAACAGCAACCTCAAGTTTCTG
  GAAGTGAAACAAAGCTTCCTGAGTGACTCTTCTGTGCGGATTCTTTGTGACCACGTAACC
  CGTAGCACCTGTCATCTGCAGAAAGTGGAGATTAAAAACGTCACCCCTGACACCGCGTAC
  CGGGACTTCTGTCTTGCTTTCATTGGGAAGAAGACCCTCACGCACCTGACCCTGGCAGGG
  CACATCGAGTGGGAACGCACGATGATGCTGATGCTGTGTGACCTGCTCAGAAATCATAAA
  TGCAACCTGCAGTACCTGAGGTTGGGAGGTCACTGTGCCACCCCGGAGCAGTGGGCTGAA
  TTCTTCTATGTCCTCAAAGCCAACCAGTCCCTGAAGCACCTGCGTCTCTCAGCCAATGTG
  CTCCTGGATGAGGGTGCCATGTTGCTGTACAAGACCATGACACGCCCAAAACACTTCCTG
  CAGATGTTGTCGTTGGAAAACTGTCGTCTTACAGAAGCCAGTTGCAAGGACCTTGCTGCT
  GTCTTGGTTGTCAGCAAGAAGCTGACACACCTGTGCTTGGCCAAGAACCCCATTGGGGAT
  ACAGGGGTGAAGTTTCTGTGTGAGGGCTTGAGTTACCCTGATTGTAAACTGCAGACCTTG
  GTGTTACAGCAATGCAGCATAACCAAGCTTGGCTGTAGATATCTCTCAGAGGCGCTCCAA
  GAAGCCTGCAGCCTCACAAACCTGGACTTGAGTATCAACCAGATAGCTCGTGGATTGTGG
  ATTCTCTGTCAGGCATTAGAGAATCCAAACTGTAACCTAAAACACCTACGGTTGAAGACC
  TATGAAACTAATTTGGAAATCAAGAAGCTGTTGGAGGAAGTGAAAGAAAAGAATCCCAAG
  CTGACTATTGATTGCAATGCTTCCGGGGCAACGGCACCTCCGTGCTGTGACTTTTTTTGC
  TGA
  
• Restriction Sites: Please inquire
• ACCN: NM_206828
• ORF Size: 2943 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_206828.2, NP_996611.2
• RefSeq Size: 3245
• RefSeq ORF: 2943
• Locus ID: 199713
• Gene Summary: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 3, resulting in a shorter protein (isoform 2), compared to isoform 3.