Nogo A (RTN4) (NM_207521) Human Untagged Clone

CAT#: SC308608

RTN4 (untagged)-Human reticulon 4 (RTN4), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RTN4
• Synonyms: ASY; Nbla00271; Nbla10545; NI220/250; NOGO; NSP; NSP-CL; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_207521, the custom clone sequence may differ by one or more nucleotides
  ATGGACTTGAAGGAGCAGCCAGGTAACACTATTTCGGCTGGTCAAGAGGATTTCCCATCT
  GTCCTGCTTGAAACTGCTGCTTCTCTTCCTTCTCTGTCTCCTCTCTCAGCCGCTTCTTTC
  AAAGAACATGAATACCTTGGTAATTTGTCAACAGTATTACCCACTGAAGGAACACTTCAA
  GAAAATGTCAGTGAAGCTTCTAAAGAGGTCTCAGAGAAGGCAAAAACTCTACTCATAGAT
  AGAGATTTAACAGAGTTTTCAGAATTAGAATACTCAGAAATGGGATCATCGTTCAGTGTC
  TCTCCAAAAGCAGAATCTGCCGTAATAGTAGCAAATCCTAGGGAAGAAATAATCGTGAAA
  AATAAAGATGAAGAAGAGAAGTTAGTTAGTAATAACATCCTTCATAATCAACAAGAGTTA
  CCTACAGCTCTTACTAAATTGGTTAAAGAGGATGAAGTTGTGTCTTCAGAAAAAGCAAAA
  GACAGTTTTAATGAAAAGAGAGTTGCAGTGGAAGCTCCTATGAGGGAGGAATATGCAGAC
  TTCAAACCATTTGAGCGAGTATGGGAAGTGAAAGATAGTAAGGAAGATAGTGATATGTTG
  GCTGCTGGAGGTAAAATCGAGAGCAACTTGGAAAGTAAAGTGGATAAAAAATGTTTTGCA
  GATAGCCTTGAGCAAACTAATCACGAAAAAGATAGTGAGAGTAGTAATGATGATACTTCT
  TTCCCCAGTACGCCAGAAGGTATAAAGGATCGTTCAGGAGCATATATCACATGTGCTCCC
  TTTAACCCAGCAGCAACTGAGAGCATTGCAACAAACATTTTTCCTTTGTTAGGAGATCCT
  ACTTCAGAAAATAAGACCGATGAAAAAAAAATAGAAGAAAAGAAGGCCCAAATAGTAACA
  GAGAAGAATACTAGCACCAAAACATCAAACCCTTTTCTTGTAGCAGCACAGGATTCTGAG
  ACAGATTATGTCACAACAGATAATTTAACAAAGGTGACTGAGGAAGTCGTGGCAAACATG
  CCTGAAGGCCTGACTCCAGATTTAGTACAGGAAGCATGTGAAAGTGAATTGAATGAAGTT
  ACTGGTACAAAGATTGCTTATGAAACAAAAATGGACTTGGTTCAAACATCAGAAGTTATG
  CAAGAGTCACTCTATCCTGCAGCACAGCTTTGCCCATCATTTGAAGAGTCAGAAGCTACT
  CCTTCACCAGTTTTGCCTGACATTGTTATGGAAGCACCATTGAATTCTGCAGTTCCTAGT
  GCTGGTGCTTCCGTGATACAGCCCAGCTCATCACCATTAGAAGCTTCTTCAGTTAATTAT
  GAAAGCATAAAACATGAGCCTGAAAACCCCCCACCATATGAAGAGGCCATGAGTGTATCA
  CTAAAAAAAGTATCAGGAATAAAGGAAGAAATTAAAGAGCCTGAAAATATTAATGCAGCT
  CTTCAAGAAACAGAAGCTCCTTATATATCTATTGCATGTGATTTAATTAAAGAAACAAAG
  CTTTCTGCTGAACCAGCTCCGGATTTCTCTGATTATTCAGAAATGGCAAAAGTTGAACAG
  CCAGTGCCTGATCATTCTGAGCTAGTTGAAGATTCCTCACCTGATTCTGAACCAGTTGAC
  TTATTTAGTGATGATTCAATACCTGACGTTCCACAAAAACAAGATGAAACTGTGATGCTT
  GTGAAAGAAAGTCTCACTGAGACTTCATTTGAGTCAATGATAGAATATGAAAATAAGGAA
  AAACTCAGTGCTTTGCCACCTGAGGGAGGAAAGCCATATTTGGAATCTTTTAAGCTCAGT
  TTAGATAACACAAAAGATACCCTGTTACCTGATGAAGTTTCAACATTGAGCAAAAAGGAG
  AAAATTCCTTTGCAGATGGAGGAGCTCAGTACTGCAGTTTATTCAAATGATGACTTATTT
  ATTTCTAAGGAAGCACAGATAAGAGAAACTGAAACGTTTTCAGATTCATCTCCAATTGAA
  ATTATAGATGAGTTCCCTACATTGATCAGTTCTAAAACTGATTCATTTTCTAAATTAGCC
  AGGGAATATACTGACCTAGAAGTATCCCACAAAAGTGAAATTGCTAATGCCCCGGATGGA
  GCTGGGTCATTGCCTTGCACAGAATTGCCCCATGACCTTTCTTTGAAGAACATACAACCC
  AAAGTTGAAGAGAAAATCAGTTTCTCAGATGACTTTTCTAAAAATGGGTCTGCTACATCA
  AAGGTGCTCTTATTGCCTCCAGATGTTTCTGCTTTGGCCACTCAAGCAGAGATAGAGAGC
  ATAGTTAAACCCAAAGTTCTTGTGAAAGAAGCTGAGAAAAAACTTCCTTCCGATACAGAA
  AAAGAGGACAGATCACCATCTGCTATATTTTCAGCAGAGCTGAGTAAAACTTCAGTTGTT
  GACCTCCTGTACTGGAGAGACATTAAGAAGACTGGAGTGGTGTTTGGTGCCAGCCTATTC
  CTGCTGCTTTCATTGACAGTATTCAGCATTGTGAGCGTAACAGCCTACATTGCCTTGGCC
  CTGCTCTCTGTGACCATCAGCTTTAGGATATACAAGGGTGTGATCCAAGCTATCCAGAAA
  TCAGATGAAGGCCACCCATTCAGGGCATATCTGGAATCTGAAGTTGCTATATCTGAGGAG
  TTGGTTCAGAAGTACAGTAATTCTGCTCTTGGTCATGTGAACTGCACGATAAAGGAACTC
  AGGCGCCTCTTCTTAGTTGATGATTTAGTTGATTCTCTGAAGTTTGCAGTGTTGATGTGG
  GTATTTACCTATGTTGGTGCCTTGTTTAATGGTCTGACACTACTGATTTTGGCTCTCATT
  TCACTCTTCAGTGTTCCTGTTATTTATGAACGGCATCAGGCACAGATAGATCATTATCTA
  GGACTTGCAAATAAGAATGTTAAAGATGCTATGGCTAAAATCCAAGCAAAAATCCCTGGA
  TTGAAGCGCAAAGCTGAATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_207521
• ORF Size: 2961 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_207521.1, NP_997404.1
• RefSeq Size: 4129
• RefSeq ORF: 2961
• Locus ID: 57142
• Protein Families: Transmembrane
• Gene Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (5), also known as hRTN4-E, differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (E) has a shorter N-terminus, compared to isoform A. This variant (5), along with variants 6, 7, 8, 9, 10, and 11, encodes isoform E.