PDLIM7 (NM_213636) Human Untagged Clone

CAT#: SC308689

PDLIM7 (untagged)-Human PDZ and LIM domain 7 (enigma) (PDLIM7), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDLIM7
• Synonyms: LMP1; LMP3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC014521 edited
  GGCACGAGGCTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCC
  GGCATCATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCTG
  CAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAA
  GCGGCGCAGGCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCG
  GGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAGCGCCTCAGC
  CTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGGCCTCCGCCCCCGCC
  GCGGACCCTCCGCGGTACACCTTTGCACCCAGCGTCTCCCTCAACAAGACGGCCCGGCCC
  TTTGGGGCGCCCCCGCCCGCTGACAGCGCCCCGCAGCAGAATGGACAGCCGCTCCGACCG
  CTGGTCCCAGATGCCAGCAAGCAGCGGCTGATGGAGAACACAGAGGACTGGCGGCCGCGG
  CCGGGGACAGGCCAGTCGCGTTCCTTCCGCATCCTTGCCCACCTCACAGGCACCGAGTTC
  ATGCAAGACCCGGATGAGGAGCACCTGAAGAAATCAAGGGAAAAGTATGTCCTGGAGCTG
  CAGAGCCCACGCTACACCCGCCTCCGGGACTGGCACCACCAGCGCTCTGCCCACGTGCTC
  AACGTGCAGTCGTAGCCCGGCCCTCTCCAGCCGGCTGCCCTCTCTGCCTCCCTCTTTCTG
  TTCCTCCTGCCCAGGGCACCCCCTTAGTGCCTCCAGCTTCTGCCTACCTCACCCCCCCTT
  TCGTGCCCCTGGCCTGAGCCTCCTGCTGGCCTGGCCCTGGCCGCCCACCTGGGTTCATCT
  GACACTGCCTTCCCTCTTTGCCCTGTGGTACTGCTGTCTGCCAGGTCTGTGCTGCCTTGG
  GCATGGAATAAACATTCTCAGCCCTGAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC014521 unedited
  GTTCAAAATTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCTCCCT
  GGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCC
  TTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGAC
  TTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAGGCCGGA
  GTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACAC
  ATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGG
  GCCCAGCCGGTTCAGAGCAAACCGCAGAAGGCCTCCGCCCCCGCCGCGGACCCTCCGCGG
  TACACCTTTGCACCCAGCGTCTCCCTCAACAAGACGGCCCGGCCCTTTGGGGCGCCCCCG
  CCCGCTGACAGCGCCCCGCAGCAGAATGGACAGCCGCTCCGACCGCTGGTCCCAGATGCC
  AGCAAGCAGCGGCTGATGGAGAACACAGAGGACTGGCGGCCGCGGCCGGGGACAGGCCAG
  TCGCGTTCCTTCCGCATCCTTGCCCACCTCACAGGCACCGAGTTCATGCAAGACCCGGAT
  GAGGAGCACCTGAAGAAATCAAGGGAAAAGTATGTCCTGGAGCTGCAGAGCCCACGCTAC
  ACCCGCCTCCGGGACTGGCACCACCAGCGCTCTGCCCACGTGCTCAACGTGCAGTCGTAG
  CCCGGCCCCTCTCAGCCGGCTGCCCTCTCTGGCTCCCTCTTTCTGGTTCTCCTGCCCAGG
  GCACCCCCCTTATGCCTCCAGCTTCTGGCTACCTAAACCCCCTTTCGTGCCCCTTGCCTG
  AGCCTCTGCTGGCCTGGCCCTGCACGACCACTA
  
• Restriction Sites: Please inquire
• ACCN: NM_213636
• ORF Size: 669 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_213636.1, NP_998801.1
• RefSeq Size: 1005
• RefSeq ORF: 669
• Locus ID: 9260
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) lacks several exons and has an alternate 3' terminal exon, compared to variant 1. The resulting isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.