PCDHA5 (NM_031501) Human Untagged Clone

CAT#: SC308764

PCDHA5 (untagged)-Human protocadherin alpha 5 (PCDHA5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA5
• Synonyms: CNR6; CNRN6; CNRS6; CRNR6; PCDH-ALPHA5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031501, the custom clone sequence may differ by one or more nucleotides
  ATGGTATATTCCCGGAGAGGAAGTCTGGGATCCCGGCTCCTGCTGCTCTGGCTTCTCCTT
  GCCTACTGGAAGGCAGGGAGCGGCCAGCTCCACTACTCGATCCCGGAGGAAGCCAAACAC
  GGAACCTTCGTTGGCCGCATCGCGCAGGACCTAGGGCTGGAGCTGGCGGAGCTGGTGCCG
  CGCCTGTTCCGGGTGGCGTCCAAGGGCCGCGGGGACCTTCTGGAGGTAAATCTGCAGAAT
  GGCATTTTGTTTGTGAATTCTCGGATCGACCGGGAGGAGCTGTGCCGGCGGAGGGCGGAG
  TGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGAGGTG
  GCAGTGAAGGACATCAATGACAATCCGCCCAGGTTCTCCAGACAAGAACAAAGATTATTC
  ATTTTAGAGTCAAGAATGCCAGATTCGCGGTTTCCGCTAGAGGGCGCGTCGGATTTGGAT
  ATTGGAGCAAATGCACAATTGAGATACAGGTTAAATCCAAACGAATATTTTGACTTAGAT
  GTTAAAACAAATGAAGAAGAAACGAACTTTTTAGAGCTGGTTTTGAGGAAATCCTTAGAT
  AGAGAAGAAACACAAGAACACCGTTTATTAGTGATTGCAACTGATGGAGGAAAACCCGAA
  CTAACAGGTACAGTTCAGTTGTTGATCAATGTATTGGATGCTAATGATAACGCCCCAGAA
  TTTGATAAATCCATTTATAATGTCAGATTGTTGGAAAATGCACCAAGTGGGACATTAGTT
  ATTAAACTGAACGCCTCAGATGCAGATGAGGGCATCAATAAGGAAATAGTGTATTTCTTT
  AGTAATCTTGTTCTTGACGATGTAAAGTCCAAATTTATAATTAATTCTAATACTGGTGAA
  ATAAAAGTTAACGGGGAACTGGATTATGAAGACTATAACTCATATGAAATTAATATTGAT
  GCCATGGATAAAAGTACATTCCCATTATCAGGACACTGTAAAGTAGTAGTGAAACTCCTG
  GATGTGAATGATAATACCCCAGAGATGGCCATAACCACCCTTTTCCTGCCTGTCAAAGAG
  GACGCTCCACTCAGCACGGTCATTGCTCTGATCAGCGTGTCTGACCGTGACTCAGGTGCC
  AACGGGCAGGTGACCTGCTCCCTAATGCCCCACGTTCCCTTCAAGCTGGTGTCCACCTTC
  AAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTGTCGGTCTAT
  GAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACCGCCAGCGTG
  TCTGTGGAAGTGGCCGACGTGAACGACAACGCTCCGGCGTTCGCGCAGCCCCAGTATACC
  GTGTTCGTGAAGGAGAACAACCCGCCAGGCTGCCACATCTTCACGGTGTCTGCACGGGAC
  GCGGACGCGCAGGAGAACGCCCTGGTGTCCTACTCGCTGGTGGAGCGGCGGGTGGGCGAG
  CGCCCGCTGTCGAGTTACGTTTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
  CCGCTGGACCACGAGGAAGTGGAGCTGCTGCAGTTCCAGGTGAGCGCGCGCGACGCGGGC
  GTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
  GCGCCGGCGCTGCTGGTGCCTCGAGTGGGTGGCACCGGCGGCGCAGTGAGCGAGCTGGTG
  CCGAGGTCAGTGGGTGCGGGCCACGTGGTGGCGAAGGTGCGCGCAGTGGACCCTGATTCG
  GGCTACAACGCTTGGCTTTCGTATGAGCTGCAGCCAGCGCCTGGCAGTGCGCGCATCCCG
  TTCCGCGTGGGGCTGTACACAGGCGAGATCAGCACAACACGCTCTCTGGATGAGACCGAA
  GCACCGCGCCACCGCCTTCTGGTGCTGGTGAAGGACCATGGAGAGCCCCCGCTGACAGCC
  ACAGCCACAGTGCTGGTGTCGCTGGTGGAAAGTGGCCAGGCGCCGAAGGCCTCATCGCGG
  GCGTCGGCGGGCGCTGTGGGTCCCGAGGCTGCCCTGGTGGATGTCAACGTGTACCTGATC
  ATCGCCATCTGTGCGGTGTCCAGCCTGCTGGTGCTCACGCTGCTGCTGTACACCGCGCTG
  CGGTGCTCGGCGCAGCCCACCGAGGCCGTGTGCACACGGGGCAAGCCCACTCTGTTGTGC
  TCCAGCGCGGTGGGGAGCTGGTCGTACTCGCAGCAGAGGAGACAGAGGGTGTGCTCTGGG
  GAAGCTCCACCCAAAACAGACCTCATGGCCTTCAGTCCAAGCCTTCCTCAGGGTCCCACC
  TCTACAGACAACGTGAGTTTTCTAATATTAACATCCATCTTTCCCTCCCAATTTTCAAAT
  ATTAAATGTCACATTCACCCACTTTTTTTGTATTTAAAAATTATGTCTTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_031501
• ORF Size: 2451 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031501.1, NP_113689.1
• RefSeq Size: 2451
• RefSeq ORF: 2451
• Locus ID: 56143
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929.