Plexin A2 (PLXNA2) (NM_025179) Human Untagged Clone

CAT#: SC308779

PLXNA2 (untagged)-Human plexin A2 (PLXNA2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLXNA2
• Synonyms: OCT; PLXN2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_025179, the custom clone sequence may differ by one or more nucleotides
  ATGGAACAGAGGCGGCCCTGGCCCCGGGCCCTGGAGGTGGACAGCCGCTCTGTGGTCCTG
  CTCTCAGTGGTCTGGGTGCTGCTGGCCCCCCCAGCAGCCGGCATGCCTCAGTTCAGCACC
  TTCCACTCTGAGAATCGTGACTGGACCTTCAACCACTTGACCGTCCACCAAGGGACGGGG
  GCCGTCTATGTGGGGGCCATCAACCGGGTCTATAAGCTGACAGGCAACCTGACCATCCAG
  GTGGCTCATAAGACAGGGCCAGAAGAGGACAACAAGTCTTGTTACCCGCCCCTCATCGTG
  CAGCCCTGCAGCGAAGTGCTCACCCTCACCAACAATGTCAACAAGCTGCTCATCATTGAC
  TACTCTGAGAACCGCCTGCTGGCCTGTGGGAGCCTCTACCAGGGGGTCTGCAAGCTGCTG
  CGGCTGGATGACCTCTTCATCCTGGTGGAGCCATCCCACAAGAAGGAGCACTACCTGTCC
  AGTGTCAACAAGACGGGCACCATGTACGGGGTGATTGTGCGCTCTGAGGGTGAGGATGGC
  AAGCTCTTCATCGGCACGGCTGTGGATGGGAAGCAGGATTACTTCCCGACCCTGTCCAGC
  CGGAAGCTGCCCCGAGACCCTGAGTCCTCAGCCATGCTCGACTATGAGCTACACAGCGAT
  TTTGTCTCCTCTCTCATCAAGATCCCTTCAGACACCCTGGCCCTGGTCTCCCACTTTGAC
  ATCTTCTACATCTACGGCTTTGCTAGTGGGGGCTTTGTCTACTTTCTCACTGTCCAGCCC
  GAGACCCCTGAGGGTGTGGCCATCAACTCCGCTGGAGACCTCTTCTACACCTCACGCATC
  GTGCGGCTCTGCAAGGATGACCCCAAGTTCCACTCATACGTGTCCCTGCCCTTCGGCTGC
  ACCCGGGCCGGGGTGGAATACCGCCTCCTGCAGGCTGCTTACCTGGCCAAGCCTGGGGAC
  TCACTGGCCCAGGCCTTCAATATCACCAGCCAGGACGATGTACTCTTTGCCATCTTCTCC
  AAAGGGCAGAAGCAGTATCACCACCCGCCCGATGACTCTGCCCTGTGTGCCTTCCCTATC
  CGGGCCATCAACTTGCAGATCAAGGAGCGCCTGCAGTCCTGCTACCAGGGCGAGGGCAAC
  CTGGAGCTCAACTGGCTGCTGGGGAAGGACGTCCAGTGCACCAAGGCGCCTGTCCCCATC
  GATGATAACTTCTGTGGACTGGACATCAACCAGCCCCTGGGAGGCTCAACTCCAGTGGAG
  GGCCTGACCCTGTACACCACCAGCAGGGACCGCATGACCTCTGTGGCCTCCTACGTTTAC
  AACGGCTACAGCGTGGTTTTTGTGGGGACTAAGAGTGGCAAGCTGAAAAAGATTCGGGCC
  GACGGTCCCCCCCATGGTGGGGTCCAGTACGAGATGGTCTCTGTGCTCAAGGACGGAAGC
  CCCATCCTCCGGGACATGGCCTTCTCCATTGATCAGCGCTACCTGTACGTCATGTCTGAG
  AGACAGGTCACCAGGGTCCCCGTGGAGTCATGTGAGCAGTATACGACTTGTGGGGAGTGC
  CTGAGCTCTGGGGACCCTCACTGTGGCTGGTGTGCCCTGCACAACATGTGCTCCCGCAGG
  GACAAATGCCAACAGGCCTGGGAACCTAATCGATTTGCTGCCAGCATCAGCCAGTGTGTG
  AGCCTTGCAGTGCATCCCAGCAGCATCTCAGTATCTGAGCACAGCCGGTTGCTTAGCCTG
  GTAGTGAGTGATGCTCCTGATCTATCTGCGGGTATCGCCTGTGCCTTTGGGAACCTGACA
  GAGGTGGAGGGGCAGGTGTCCGGGAGCCAGGTCATCTGCATCTCACCTGGGCCCAAGGAT
  GTCCCTGTCATCCCGCTGGATCAAGACTGGTTTGGGCTGGAGCTACAGCTGAGGTCCAAG
  GAGACAGGGAAGATATTTGTCAGCACCGAGTTCAAGTTTTACAACTGCAGTGCCCACCAA
  CTGTGCCTGTCCTGTGTCAACAGCGCCTTCCGCTGCCATTGGTGCAAGTACCGCAACCTC
  TGCACTCATGACCCCACCACCTGCTCCTTCCAGGAGGGCCGGATCAATATTTCAGAGGAC
  TGTCCCCAGCTGGTGCCCACAGAGGAGATCTTGATTCCAGTCGGGGAGGTAAAGCCAATC
  ACCCTTAAGGCGCGAAATCTGCCCCAGCCGCAGTCCGGCCAGCGAGGCTATGAGTGTGTC
  CTCAACATACAAGGAGCCATCCACCGGGTCCCCGCTCTGCGCTTCAACAGCTCCAGCGTT
  CAGTGTCAGAACAGCTCGTACCAGTATGATGGCATGGACATCAGCAATCTGGCCGTGGAT
  TTCGCTGTGGTGTGGAACGGCAATTTCATCATTGACAACCCTCAGGACCTGAAAGTCCAT
  CTCTACAAGTGTGCAGCCCAGCGGGAGAGCTGCGGCCTCTGCCTCAAGGCCGACCGGAAG
  TTTGAGTGTGGCTGGTGCAGCGGCGAGCGCAGGTGCACCCTCCACCAGCACTGTACCAGC
  CCTTCCAGCCCCTGGCTCGACTGGTCCAGCCACAATGTCAAGTGCTCCAACCCTCAAATC
  ACCGAGATTTTGACGGTGTCTGGACCGCCGGAAGGAGGGACGCGAGTGACCATCCATGGC
  GTGAACCTGGGTCTGGACTTCTCCGAGATCGCCCACCATGTGCAGGTGGCTGGGGTGCCC
  TGCACGCCCCTCCCAGGGGAATACATCATCGCTGAGCAGATTGTCTGTGAGATGGGCCAT
  GCCCTCGTGGGAACCACCTCCGGGCCAGTACGCCTGTGTATTGGCGAGTGTAAGCCAGAG
  TTCATGACGAAGTCCCATCAGCAGTACACCTTCGTGAACCCTTCTGTGCTGTCACTCAAC
  CCAATCCGAGGTCCCGAGTCAGGAGGCACTATGGTGACCATTACCGGCCATTACCTTGGG
  GCTGGGAGCAGCGTGGCAGTCTACCTGGGCAACCAGACCTGCGAGTTCTACGGGAGGTCA
  ATGAGTGAGATCGTGTGTGTCTCACCCCCATCATCCAATGGCCTTGGCCCGGTCCCTGTT
  TCTGTGAGTGTCGACCGAGCCCATGTGGATAGCAACCTGCAGTTTGAGTACATAGATGAC
  CCTCGGGTCCAGCGCATCGAGCCAGAGTGGAGCATTGCCAGTGGCCACACACCCCTGACC
  ATCACAGGCTTCAACCTGGATGTCATTCAGGAGCCAAGGATCCGAGTCAAATTCAATGGC
  AAAGAATCTGTCAATGTGTGTAAAGTTGTGAACACAACCACCCTCACCTGCCTGGCACCC
  TCTCTGACCACGGACTACCGCCCTGGCCTGGACACTGTGGAACGCCCAGATGAGTTTGGA
  TTTGTCTTTAACAATGTCCAATCCTTGCTAATTTACAACGACACCAAGTTTATCTACTAC
  CCCAACCCGACCTTTGAACTGCTTAGCCCTACTGGAGTCTTGGATCAAAAGCCAGGATCG
  CCCATCATTCTGAAGGGCAAAAACCTCTGCCCTCCTGCCTCTGGAGGGGCCAAACTCAAC
  TACACTGTGCTCATCGGAGAGACCCCTTGTGCTGTCACCGTATCTGAGACCCAGCTTCTC
  TGCGAGCCTCCCAACCTCACCGGGCAGCACAAGGTCATGGTTCACGTGGGCGGGATGGTG
  TTCTCGCCTGGCTCGGTGAGTGTCATCTCAGACAGCTTGCTGACCCTGCCAGCCATCGTC
  AGCATCGCGGCCGGCGGCAGCCTCCTCCTCATCATCGTCATCATCGTCCTCATTGCCTAC
  AAGCGCAAGTCTCGAGAAAATGACCTCACTCTCAAGCGGCTGCAAATGCAGATGGACAAT
  CTGGAGTCCCGTGTGGCCTTGGAGTGCAAGGAAGCTTTTGCTGAGCTCCAGACGGATATC
  AATGAGTTGACCAGTGACCTGGACCGCTCAGGAATCCCTTACCTGGACTATCGTACCTAC
  GCTATGCGAGTCCTGTTCCCGGGCATCGAGGACCACCCCGTCCTGCGGGAGCTGGAGGTA
  CAAGGAAACGGGCAGCAGCACGTGGAGAAGGCCCTGAAGCTCTTTGCCCAGCTCATCAAC
  AACAAGGTGTTCCTGCTGACCTTCATCCGCACCCTGGAGCTGCAGCGCAGTTTCTCCATG
  CGCGACCGGGGCAACGTGGCTTCGCTCATCATGACCGGCCTGCAGGGCCGCCTGGAATAT
  GCCACTGATGTCCTCAAGCAGCTGCTCTCTGACCTCATCGATAAGAACCTGGAGAACAAG
  AACCACCCCAAGCTGCTACTCCGGAGGACAGAGTCTGTGGCTGAAAAGATGCTGACCAAT
  TGGTTCGCCTTCCTCCTGCACAAGTTCCTAAAGGAGTGCGCAGGGGAGCCACTCTTCATG
  CTATACTGTGCCATCAAGCAGCAGATGGAGAAGGGCCCCATTGATGCCATCACGGGCGAG
  GCCCGCTACTCCCTGAGCGAGGACAAGCTCATCCGGCAGCAGATCGAGTACAAGACCCTG
  ATCCTGAACTGCGTCAACCCTGACAACGAGAACAGTCCAGAGATCCCAGTGAAGGTGTTA
  AACTGTGACACCATCACACAGGTCAAGGAGAAGATTCTTGATGCCGTGTATAAGAATGTG
  CCCTATTCCCAGCGGCCGAGGGCAGTGGACATGGACTTGGAGTGGCGCCAAGGCCGGATC
  GCCCGGGTCGTGCTGCAAGATGAGGACATCACCACCAAGATTGAGGGTGACTGGAAGCGG
  CTCAACACACTGATGCATTATCAGGTGTCAGACAGGTCGGTGGTGGCTCTGGTCCCCAAA
  CAGACCTCCTCCTACAACATCCCTGCCTCTGCCAGCATCTCCCGGACGTCCATCAGCAGA
  TACGACTCCTCCTTCAGGTATACGGGCAGCCCCGACAGCCTGCGGTCCCGGGCCCCGATG
  ATCACCCCAGACCTGGAAAGTGGGGTCAAGGTGTGGCATCTGGTGAAGAACCATGACCAC
  GGTGACCAGAAGGAGGGTGACCGGGGCAGCAAGATGGTGTCCGAGATCTACCTGACCCGG
  CTACTGGCCACCAAGGGCACCCTGCAGAAGTTTGTGGACGACTTGTTTGAGACCTTGTTC
  AGCACTGTGCACCGGGGCAGCGCTCTCCCCCTGGCCATCAAGTACATGTTTGATTTCCTA
  GATGAGCAGGCAGACAGGCACAGCATCCATGACACAGATGTGCGGCACACCTGGAAAAGC
  AACTGCCTCCCTCTGCGCTTCTGGGTGAACGTGATTAAGAACCCCCAGTTCGTGTTTGAC
  ATCCACAAGGGCAGCATCACGGACGCCTGCCTCTCTGTGGTGGCCCAGACCTTCATGGAC
  TCTTGTTCAACGTCAGAGCACCGGCTGGGCAAGGACTCCCCCTCCAACAAGCTGCTCTAT
  GCCAAGGACATCCCCAGCTACAAGAGCTGGGTGGAGAGATACTACGCAGACATCGCCAAG
  CTCCCAGCCATCAGTGACCAGGACATGAATGCCTACCTCGCCGAGCAGTCCCGCCTGCAC
  GCCGTGGAGTTCAACATGCTGAGTGCCCTCAATGAGATCTACTCCTATGTCAGCAAGTAT
  AGTGAGGAGCTCATCGGGGCCCTAGAGCAGGATGAGCAGGCACGGCGGCAGCGGCTGGCT
  TATAAGGTGGAGCAGCTCATTAATGCCATGTCCATTGAGAGCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_025179
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_025179.2, NP_079455.2
• RefSeq Size: 6263 bp
• RefSeq ORF: 5685 bp
• Locus ID: 5362
• Cytogenetics: 1q32.2
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• Gene Summary: 'This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]'