CEP290 (NM_025114) Human Untagged Clone

CAT#: SC308782

CEP290 (untagged)-Human centrosomal protein 290kDa (CEP290)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CEP290
• Synonyms: 3H11Ag; BBS14; CT87; JBTS5; LCA10; MKS4; NPHP6; POC3; rd16; SLSN6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_025114, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCACCTAATATAAACTGGAAAGAAATAATGAAAGTTGACCCAGATGACCTGCCCCGTCAAGAAGAAC
  TGGCAGATAATTTATTGATTTCCTTATCCAAGGTGGAAGTAAATGAGCTAAAAAGTGAAAAGCAAGAAAA
  TGTGATACACCTTTTCAGAATTACTCAGTCACTAATGAAGATGAAAGCTCAAGAAGTGGAGCTGGCTTTG
  GAAGAAGTAGAAAAAGCTGGAGAAGAACAAGCAAAATTTGAAAATCAATTAAAAACTAAAGTAATGAAAC
  TGGAAAATGAACTGGAGATGGCTCAGCAGTCTGCAGGTGGACGAGATACTCGGTTTTTACGTAATGAAAT
  TTGCCAACTTGAAAAACAATTAGAACAAAAAGATAGAGAATTGGAGGACATGGAAAAGGAGTTGGAGAAA
  GAGAAGAAAGTTAATGAGCAATTGGCTCTTCGAAATGAGGAGGCAGAAAATGAAAACAGCAAATTAAGAA
  GAGAGAACAAACGTCTAAAGAAAAAGAATGAACAACTTTGTCAGGATATTATTGACTACCAGAAACAAAT
  AGATTCACAGAAAGAAACACTTTTATCAAGAAGAGGGGAAGACAGTGACTACCGATCACAGTTGTCTAAA
  AAAAACTATGAGCTTATCCAATATCTTGATGAAATTCAGACTTTAACAGAAGCTAATGAGAAAATTGAAG
  TTCAGAATCAAGAAATGAGAAAAAATTTAGAAGAGTCTGTACAGGAAATGGAGAAGATGACTGATGAATA
  TAATAGAATGAAAGCTATTGTGCATCAGACAGATAATGTAATAGATCAGTTAAAAAAAGAAAACGATCAT
  TATCAACTTCAAGTGCAGGAGCTTACAGATCTTCTGAAATCAAAAAATGAAGAAGATGATCCAATTATGG
  TAGCTGTCAATGCAAAAGTAGAAGAATGGAAGCTAATTTTGTCTTCTAAAGATGATGAAATTATTGAGTA
  TCAGCAAATGTTACATAACCTAAGGGAGAAACTTAAGAATGCTCAGCTTGATGCTGATAAAAGTAATGTT
  ATGGCTCTACAGCAGGGTATACAGGAACGAGACAGTCAAATTAAGATGCTCACCGAACAAGTAGAACAAT
  ATACAAAAGAAATGGAAAAGAATACTTGTATTATTGAAGATTTGAAAAATGAGCTCCAAAGAAACAAAGG
  TGCTTCAACCCTTTCTCAACAGACTCATATGAAAATTCAGTCAACGTTAGACATTTTAAAAGAGAAAACT
  AAAGAGGCTGAGAGAACAGCTGAACTGGCTGAGGCTGATGCTAGGGAAAAGGATAAAGAATTAGTTGAGG
  CTCTGAAGAGGTTAAAAGATTATGAATCGGGAGTATATGGTTTAGAAGATGCTGTCGTTGAAATAAAGAA
  TTGTAAAAACCAAATTAAAATAAGAGATCGAGAGATTGAAATATTAACAAAGGAAATCAATAAACTTGAA
  TTGAAGATCAGTGATTTCCTTGATGAAAATGAGGCACTTAGAGAGCGTGTGGGCCTTGAACCAAAGACAA
  TGATTGATTTAACTGAATTTAGAAATAGCAAACACTTAAAACAGCAGCAGTACAGAGCTGAAAACCAGAT
  TCTTTTGAAAGAGATTGAAAGTCTAGAGGAAGAACGACTTGATCTGAAAAAAAAAATTCGTCAAATGGCT
  CAAGAAAGAGGAAAAAGAAGTGCAACTTCAGGATTAACCACTGAGGACCTGAACCTAACTGAAAACATTT
  CTCAAGGAGATAGAATAAGTGAAAGAAAATTGGATTTATTGAGCCTCAAAAATATGAGTGAAGCACAATC
  AAAGAATGAATTTCTTTCAAGAGAACTAATTGAAAAAGAAAGAGATTTAGAAAGGAGTAGGACAGTGATA
  GCCAAATTTCAGAATAAATTAAAAGAATTAGTTGAAGAAAATAAGCAACTTGAAGAAGGTATGAAAGAAA
  TATTGCAAGCAATTAAGGAAATGCAGAAAGATCCTGATGTTAAAGGAGGAGAAACATCTCTAATTATCCC
  TAGCCTTGAAAGACTAGTTAATGCTATAGAATCAAAGAATGCAGAAGGAATCTTTGATGCGAGTCTGCAT
  TTGAAAGCCCAAGTTGATCAGCTTACCGGAAGAAATGAAGAATTAAGACAGGAGCTCAGGGAATCTCGGA
  AAGAGGCTATAAATTATTCACAGCAGTTGGCAAAAGCTAATTTAAAGATAGACCATCTTGAAAAAGAAAC
  TAGTCTTTTACGACAATCAGAAGGATCGAATGTTGTTTTTAAAGGAATTGACTTACCTGATGGGATAGCA
  CCATCTAGTGCCAGTATCATTAATTCTCAGAATGAATATTTAATACATTTGTTACAGGAACTAGAAAATA
  AAGAAAAAAAGTTAAAGAATTTAGAAGATTCTCTTGAAGATTACAACAGAAAATTTGCTGTAATTCGTCA
  TCAACAAAGTTTGTTGTATAAAGAATACCTAAGTGAAAAGGAGACCTGGAAAACAGAATCTAAAACAATA
  AAAGAGGAAAAGAGAAAACTTGAGGATCAAGTCCAACAAGATGCTATAAAAGTAAAAGAATATAATAATT
  TGCTCAATGCTCTTCAGATGGATTCGGATGAAATGAAAAAAATACTTGCAGAAAATAGTAGGAAAATTAC
  TGTTTTGCAAGTGAATGAAAAATCACTTATAAGGCAATATACAACCTTAGTAGAATTGGAGCGACAACTT
  AGAAAAGAAAATGAGAAGCAAAAGAATGAATTGTTGTCAATGGAGGCTGAAGTTTGTGAAAAAATTGGGT
  GTTTGCAAAGATTTAAGGAAATGGCCATTTTCAAGATTGCAGCTCTCCAAAAAGTTGTAGATAATAGTGT
  TTCTTTGTCTGAACTAGAACTGGCTAATAAACAGTACAATGAACTGACTGCTAAGTACAGGGACATCTTG
  CAAAAAGATAATATGCTTGTTCAAAGAACAAGTAACTTGGAACACCTGGAGTGTGAAAACATCTCCTTAA
  AAGAACAAGTGGAGTCTATAAATAAAGAACTGGAGATTACCAAGGAAAAACTTCACACTATTGAACAAGC
  CTGGGAACAGGAAACTAAATTAGGTAATGAATCTAGCATGGATAAGGCAAAGAAATCAATAACCAACAGT
  GACATTGTTTCCATTTCAAAAAAAATAACTATGCTGGAAATGAAGGAATTAAATGAAAGGCAGCGGGCTG
  AACATTGTCAAAAAATGTATGAACACTTACGGACTTCGTTAAAGCAAATGGAGGAACGTAATTTTGAATT
  GGAAACCAAATTTGCTGAGCTTACCAAAATCAATTTGGATGCACAGAAGGTGGAACAGATGTTAAGAGAT
  GAATTAGCTGATAGTGTGAGCAAGGCAGTAAGTGATGCTGATAGGCAACGGATTCTAGAATTAGAGAAGA
  ATGAAATGGAACTAAAAGTTGAAGTGTCAAAACTGAGAGAGATTTCTGATATTGCCAGAAGACAAGTTGA
  AATTTTGAATGCACAACAACAATCTAGGGACAAGGAAGTAGAGTCCCTCAGAATGCAACTGCTAGACTAT
  CAGGCACAGTCTGATGAAAAGTCGCTCATTGCCAAGTTGCACCAACATAATGTCTCTCTTCAACTGAGTG
  AGGCTACTGCTCTTGGTAAGTTGGAGTCAATTACATCTAAACTGCAGAAGATGGAGGCCTACAACTTGCG
  CTTAGAGCAGAAACTTGATGAAAAAGAACAGGCTCTCTATTATGCTCGTTTGGAGGGAAGAAACAGAGCA
  AAACATCTGCGCCAAACAATTCAGTCTCTACGACGACAGTTTAGTGGAGCTTTACCCTTGGCACAACAGG
  AAAAGTTCTCCAAAACAATGATTCAACTACAAAATGACAAACTTAAGATAATGCAAGAAATGAAAAATTC
  TCAACAAGAACATAGAAATATGGAGAACAAAACATTGGAGATGGAATTAAAATTAAAGGGCCTGGAAGAG
  TTAATAAGCACTTTAAAGGATACCAAAGGAGCCCAAAAGGTAATCAACTGGCATATGAAAATAGAAGAAC
  TTCGTCTTCAAGAACTTAAACTAAATCGGGAATTAGTCAAGGATAAAGAAGAAATAAAATATTTGAATAA
  CATAATTTCTGAATATGAACGTACAATCAGCAGTCTTGAAGAAGAAATTGTGCAACAGAACAAGTTTCAT
  GAAGAAAGACAAATGGCCTGGGATCAAAGAGAAGTTGACCTGGAACGCCAACTAGACATTTTTGACCGTC
  AGCAAAATGAAATACTAAATGCGGCACAAAAGTTTGAAGAAGCTACAGGATCAATCCCTGACCCTAGTTT
  GCCCCTTCCAAATCAACTTGAGATCGCTCTAAGGAAAATTAAGGAGAACATTCGAATAATTCTAGAAACA
  CGGGCAACTTGCAAATCACTAGAAGAGAAACTAAAAGAGAAAGAATCTGCTTTAAGGTTAGCAGAACAAA
  ATATACTGTCAAGAGACAAAGTAATCAATGAACTGAGGCTTCGATTGCCTGCCACTGCAGAAAGAGAAAA
  GCTCATAGCTGAGCTAGGCAGAAAAGAGATGGAACCAAAATCTCACCACACATTGAAAATTGCTCATCAA
  ACCATTGCAAACATGCAAGCAAGGTTAAATCAAAAAGAAGAAGTATTAAAGAAGTATCAACGTCTTCTAG
  AAAAAGCCAGAGAGGAGCAAAGAGAAATTGTGAAGAAACATGAGGAAGACCTTCATATTCTTCATCACAG
  ATTAGAACTACAGGCTGATAGTTCACTAAATAAATTCAAACAAACGGCTTGGGATTTAATGAAACAGTCT
  CCCACTCCAGTTCCTACCAACAAGCATTTTATTCGTCTGGCTGAGATGGAACAGACAGTAGCAGAACAAG
  ATGACTCTCTTTCCTCACTCTTGGTCAAACTAAAGAAAGTATCACAAGATTTGGAGAGACAAAGAGAAAT
  CACTGAATTAAAAGTAAAAGAATTTGAAAATATCAAATTACAGCTTCAAGAAAACCATGAAGATGAAGTG
  AAAAAAGTAAAAGCGGAAGTAGAGGATTTAAAGTATCTTCTGGACCAGTCACAAAAGGAGTCACAGTGTT
  TAAAATCTGAACTTCAGGCTCAAAAAGAAGCAAATTCAAGAGCTCCAACAACTACAATGAGAAATCTAGT
  AGAACGGCTAAAGAGCCAATTAGCCTTGAAGGAGAAACAACAGAAAGCACTTAGTCGGGCACTTTTAGAA
  CTCCGGGCAGAAATGACAGCAGCTGCTGAAGAACGTATTATTTCTGCAACTTCTCAAAAAGAGGCCCATC
  TCAATGTTCAACAAATCGTTGATCGACATACTAGAGAGCTAAAGACACAAGTTGAAGATTTAAATGAAAA
  TCTTTTAAAATTGAAAGAAGCACTTAAAACAAGTAAAAACAGAGAAAACTCACTAACTGATAATTTGAAT
  GACTTAAATAATGAACTGCAAAAGAAACAAAAAGCCTATAATAAAATACTTAGAGAGAAAGAGGAAATTG
  ATCAAGAGAATGATGAACTGAAAAGGCAAATTAAAAGACTAACCAGTGGATTACAGGGCAAACCCCTGAC
  AGATAATAAACAAAGTCTAATTGAAGAACTCCAAAGGAAAGTTAAAAAACTAGAGAACCAATTAGAGGGA
  AAGGTGGAGGAAGTAGACCTAAAACCTATGAAAGAAAAGAATGCTAAAGAAGAATTAATTAGGTGGGAAG
  AAGGTAAAAAGTGGCAAGCCAAAATAGAAGGAATTCGAAACAAGTTAAAAGAGAAAGAGGGGGAAGTCTT
  TACTTTAACAAAGCAGTTGAATACTTTGAAGGATCTTTTTGCCAAAGCCGATAAAGAGAAACTTACTTTG
  CAGAGGAAACTAAAAACAACTGGCATGACTGTTGATCAGGTTTTGGGAATACGAGCTTTGGAGTCAGAAA
  AAGAATTGGAAGAATTAAAAAAGAGAAATCTTGACTTAGAAAATGATATATTGTATATGAGGGCCCACCA
  AGCTCTTCCTCGAGATTCTGTTGTAGAAGATTTACATTTACAAAATAGATACCTCCAAGAAAAACTTCAT
  GCTTTAGAAAAACAGTTTTCAAAGGATACATATTCTAAGCCTTCAATTTCAGGAATAGAGTCAGATGATC
  ATTGTCAGAGAGAACAGGAGCTTCAGAAGGAAAACTTGAAGTTGTCATCTGAAAATATTGAACTGAAATT
  TCAGCTTGAACAAGCAAATAAAGATTTGCCAAGATTAAAGAATCAAGTCAGAGATTTGAAGGAAATGTGT
  GAATTTCTTAAGAAAGAAAAAGCAGAAGTTCAGCGGAAACTTGGCCATGTTAGAGGGTCTGGTAGAAGTG
  GAAAGACAATCCCAGAACTGGAAAAAACCATTGGTTTAATGAAAAAAGTAGTTGAAAAAGTCCAGAGAGA
  AAATGAACAGTTGAAAAAAGCATCAGGAATATTGACTAGTGAAAAAATGGCTAATATTGAGCAGGAAAAT
  GAAAAATTGAAGGCTGAATTAGAAAAACTTAAAGCTCATCTTGGGCATCAGTTGAGCATGCACTATGAAT
  CCAAGACCAAAGGCACAGAAAAAATTATTGCTGAAAATGAAAGGCTTCGTAAAGAACTTAAAAAAGAAAC
  TGATGCTGCAGAGAAATTACGGATAGCAAAGAATAATTTAGAGATATTAAATGAGAAGATGACAGTTCAA
  CTAGAAGAGACTGGTAAGAGATTGCAGTTTGCAGAAAGCAGAGGTCCACAGCTTGAAGGTGCTGACAGTA
  AGAGCTGGAAATCCATTGTGGTTACAAGAATGTATGAAACCAAGTTAAAAGAATTGGAAACTGATATTGC
  CAAAAAAAATCAAAGCATTACTGACCTTAAACAGCTTGTAAAAGAAGCAACAGAGAGAGAACAAAAAGTT
  AACAAATACAATGAAGACCTTGAACAACAGATTAAGATTCTTAAACATGTTCCTGAAGGTGCTGAGACAG
  AGCAAGGCCTTAAACGGGAGCTTCAAGTTCTTAGATTAGCTAATCATCAGCTGGATAAAGAGAAAGCAGA
  ATTAATCCATCAGATAGAAGCTAACAAGGACCAAAGTGGAGCTGAAAGCACCATACCTGATGCTGATCAA
  CTAAAGGAAAAAATAAAAGATCTAGAGACACAGCTCAAAATGTCAGATCTAGAAAAGCAGCATTTGAAGG
  AGGAAATAAAGAAGCTGAAAAAAGAACTGGAAAATTTTGATCCTTCATTTTTTGAAGAAATTGAAGATCT
  TAAGTATAATTACAAGGAAGAAGTGAAGAAGAATATTCTCTTAGAAGAGAAGGTAAAAAAACTTTCAGAA
  CAATTGGGAGTTGAATTAACTAGCCCTGTTGCTGCTTCTGAAGAGTTTGAAGATGAAGAAGAAAGTCCTG
  TTAATTTCCCCATTTACTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_025114
• ORF Size: 7440 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_025114.3, NP_079390.3
• RefSeq Size: 7972
• RefSeq ORF: 7440
• Locus ID: 80184
• Gene Summary: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]