CENPJ (NM_018451) Human Untagged Clone

CAT#: SC308859

CENPJ (untagged)-Human centromere protein J (CENPJ)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CENPJ
• Synonyms: BM032; CENP-J; CPAP; LAP; LIP1; MCPH6; Sas-4; SASS4; SCKL4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_018451 edited
  ATTGTGGCGGCCCATTTGTAAATGCTGCGGAGATTGAGGTGTCGGTTCGTGCTGCTGAGC
  TGCCCAGGCTTCACGGAGCGGTGTTGGAAATCAATAGCTCTTCTAGCCTTTGCATTGTTT
  AAATATAATAGTGTCATTGGACTAAGATGTTCCTGATGCCAACCTCTTCAGAGTTAAACA
  GTGGGCAGAACTTCCTAACCCAGTGGGTGACCAATCCTTCTCGGGCTGGGGTCATATTAA
  ATCGTGGATTTCCTATTTTGGAAGCAGACAAAGAGAAGCGAGCAGCTGTGGACATTTCTA
  CCAGCTTTCCTATTAAAGGCACACATTTTTCTGATAGCTTCAGCTTTATAAATGAAGAAG
  ATTCACTTCTTGAAGAACAGAAGTTGGAGTCAAACAACCCTTACAAACCACAGTCAGATA
  AATCTGAAACCCATACAGCCTTTCCTTGCATTAAAAAGGGACCACAGGTAGCGGCATGTC
  ACAGTGCTCCTGGACACCAGGAAGAAAACAAAAATGACTTCATCCCAGATCTTGCGAGTG
  AATTCAAAGAAGGGGCTTATAAAGACCCACTTTTTAAAAAACTTGAACAGCTGAAAGAAG
  TACAACAGAAGAAGCAGGAACAATTGAAGAGGCAACAGTTGGAGCAACTACAGAGACTCA
  TGGAAGAACAAGAGAAGCTGCTCACCATGGTGTCTGGGCAGTGCACACTTCCAGGTTTGA
  GTTTACTGCCTGATGATCAGAGCCAGAAGCACAGGTCTCCAGGAAATACCACCACTGGAG
  AGAGAGCCACATGCTGCTTCCCATCATATGTCTACCCGGACCCAACCCAGGAAGAAACAT
  ACCCGTCCAACATTTTATCCCATGAGCAAAGCAACTTCTGTAGAACTGCTCATGGAGATT
  TTGTCTTAACTTCAAAACGTGCGTCTCCTAATTTATTTTCTGAGGCACAGTATCAAGAAG
  CACCTGTGGAAAAAAATAATTTAAAAGAAGAAAACCGTAACCATCCTACAGGAGAAAGTA
  TCTTATGTTGGGAGAAAGTGACAGAACAGATTCAGGAAGCAAATGATAAGAACTTACAAA
  AACATGATGATTCCTCAGAAGTGGCTAATATTGAAGAAAGGCCCATTAAAGCTGCTATTG
  GAGAAAGGAAACAGACCTTTGAAGATTACTTAGAAGAACAAATTCAGTTGGAAGAGCAAG
  AACTGAAGCAAAAACAGCTGAAGGAAGCAGAAGGACCATTGCCAATCAAAGCAAAACCAA
  AACAACCATTTTTAAAACGAGGAGAAGGTTTAGCTAGATTTACTAATGCCAAATCTAAGT
  TTCAAAAAGGCAAAGAAAGTAAACTAGTGACTAACCAGAGCACTTCCGAGGACCAGCCGC
  TGTTTAAAATGGATAGACAGCAACTCCAGCGGAAAACCGCTCTTAAAAATAAAGAGCTGT
  GTGCAGACAACCCTATCCTTAAAAAGGACAGTAAAGCTAGAACCAAGAGTGGTTCTGTCA
  CCCTCAGTCAGAAGCCGAAAATGCTGAAGTGTAGTAACAGGAAAAGTCTTTCTCCGTCAG
  GATTGAAAATACAGACGGGGAAGAAATGTGATGGGCAGTTTAGAGACCAGATCAAATTTG
  AAAACAAAGTCACATCTAATAATAAAGAAAATGTAACTGAGTGTCCAAAACCTTGCGATA
  CTGGCTGCACAGGGTGGAATAAGACACAAGGTAAAGACAGACTTCCTCTTTCAACAGGGC
  CGGCCAGCCGGCTGGCTGCTAAGAGCCCCATAAGGGAGACCATGAAAGAGTCTGAATCTT
  CTCTTGACGTTTCTCTTCAGAAAAAGTTAGAGACTTGGGAACGAGAAAAGGAAAAGGAAA
  ATTTGGAATTAGATGAATTTTTGTTTTTAGAACAAGCTGCTGATGAAATATCATTTTCTA
  GTAATTCCTCATTTGTACTGAAAATCTTAGAAAGGGATCAACAGATCTGCAAAGGTCACC
  GGATGTCTTCCACCCCTGTCAAAGCTGTGCCACAGAAGACAAATCCGGCAGATCCCATTA
  GTCATTGTAACCGCAGTGAGGATTTGGACCACACTGCACGTGAGAAGGAGAGTGAGTGTG
  AAGTCGCACCCAAACAACTTCATTCATTGTCCTCAGCTGATGAATTGAGGGAACAGCCTT
  GTAAAATCAGGAAAGCCGTCCAAAAGAGCACTTCTGAAAATCAGACTGAATGGAATGCAC
  GTGACGATGAAGGTGTTCCAAATAGTGACAGTAGCACTGACTCTGAGGAACAGCTTGATG
  TTACCATAAAACCATCGACTGAGGATAGAGAGAGGGGCATCAGCAGCAGAGAGGATAGCC
  CACAAGTCTGTGATGATAAGGGGCCTTTTAAGGACACCAGGACCCAAGAAGATAAAAGGA
  GAGATGTTGATCTGGATTTGTCTGATAAAGATTACAGTAGCGATGAGTCTATCATGGAAA
  GCATAAAACATAAAGTGTCTGAGCCCTCGAGATCCTCATCCCTAAGTCTGAGTAAAATGG
  ACTTTGATGATGAAAGAACTTGGACTGACCTTGAAGAGAATTTGTGTAACCATGATGTTG
  TTCTTGGGAATGAATCCACTTATGGGACGCCGCAGACATGCTACCCTAATAATGAAATAG
  GTATCCTGGACAAAACAATAAAAAGGAAGATTGCACCAGTCAAGAGGGGAGAAGACTTGA
  GCAAGTCCAGGAGGAGCAGAAGTCCTCCTACATCGGAGCTGATGATGAAATTCTTTCCTT
  CTTTGAAACCAAAACCAAAGTCAGATTCACACTTGGGAAATGAACTCAAGTTAAACATAA
  GTCAAGACCAACCACCTGGTGACAATGCTCGATCCCAGGTTTTGAGAGAGAAAATTATTG
  AATTGGAAACAGAAATAGAAAAGTTTAAAGCTGAGAACGCATCTTTAGCTAAACTTCGCA
  TTGAACGAGAAAGTGCCTTGGAAAAACTCAGGAAAGAAATTGCAGACTTCGAACAACAGA
  AAGCAAAAGAATTAGCTCGAATAGAAGAGTTTAAAAAGGAGGAGATGAGGAAGCTACAAA
  AGGAACGTAAAGTTTTTGAAAAGTATACTACAGCTGCAAGAACTTTTCCAGATAAAAAGG
  AACGTGAAGAAATACAGACTTTAAAACAGCAAATAGCAGATTTACGGGAAGATTTGAAAA
  GAAAGGAGACCAAATGGTCAAGTACACACAGCCGTCTCAGAAGCCAGATACAAATGTTAG
  TCAGAGAGAACACAGACCTCCGGGAAGAAATAAAAGTGATGGAAAGATTCCGACTGGATG
  CCTGGAAGAGAGCAGAAGCCATAGAGAGCAGCCTCGAGGTGGAGAAGAAGGACAAGCTTG
  CGAACACATCTGTTCGATTTCAAAACAGTCAGATTTCTTCAGGAACCCAGGTAGAAAAAT
  ACAAGAAAAATTATCTTCCAATGCAAGGCAATCCACCTCGAAGATCCAAGTCTGCACCTC
  CTCGTGATTTAGGCAATTTGGATAAGGGACAAGCTGCCTCTCCCAGGGAGCCACTTGAAC
  CACTGAACTTCCCAGATCCTGAATATAAAGAGGAGGAGGAAGACCAAGACATACAGGGAG
  AAATCAGTCATCCTGATGGAAAGGTGGAAAAGGTTTATAAGAATGGGTGCCGTGTTATAC
  TGTTTCCCAATGGAACTCGAAAGGAAGTGAGTGCAGATGGGAAGACCATCACTGTCACTT
  TCTTTAATGGTGACGTGAAGCAGGTCATGCCAGACCAAAGAGTGATCTACTACTATGCAG
  CTGCCCAGACCACTCACACGACATACCCGGAGGGACTGGAAGTCTTACATTTCTCAAGTG
  GACAAATAGAAAAACATTACCCAGATGGAAGAAAAGAAATCACGTTTCCTGACCAGACTG
  TTAAAAACTTATTTCCTGATGGACAAGAAGAAAGCATTTTCCCAGATGGTACAATTGTCA
  GAGTACAACGTGATGGCAACAAACTCATAGAGTTTAATAATGGCCAAAGAGAACTACATA
  CTGCCCAGTTCAAGAGACGGGAATACCCAGATGGCACTGTTAAAACCGTATATGCAAACG
  GTCATCAAGAAACGAAGTACAGATCCGGTCGGATAAGAGTTAAGGACAAGGAGGGTAATG
  TGCTAATGGACACGGAGCTGTGACGATCCTCATGTGATCATGAAGTAACAGTAACTGACT
  TTTTATGTTAAAAAATGTACATTTACTGTGGATTCTGTTTAATTTATTGTGTATGTGTGG
  GGAAAAGATTGGATTCTAAAATAAAAGTTTACCCTGTGGCAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018451
• ORF Size: 4017 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid.

Reference Data

• RefSeq: NM_018451.2, NP_060921.2
• RefSeq Size: 4387
• RefSeq ORF: 4017
• Locus ID: 55835
• Gene Summary: This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  Transcript Variant: This variant (1) represents the protein coding transcript.