TRF1 (TERF1) (NM_017489) Human Untagged Clone

CAT#: SC308887

TERF1 (untagged)-Human telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TERF1
• Synonyms: hTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_017489 edited
  TTTAACATGGCGGAGGATGTTTCCTCAGCGGCCCCGAGCCCGCGGGGCTGTGCGGATGGT
  AGGGATGCCGACCCTACTGAGGAGCAGATGGCAGAAACAGAGAGAAACGACGAGGAGCAG
  TTCGAATGCCAGGAACTGCTCGAGTGCCAGGTGCAGGTGGGGGCCCCCGAGGAGGAGGAG
  GAGGAGGAGGAGGACGCGGGCCTGGTGGCCGAGGCCGAGGCCGTGGCTGCCGGCTGGATG
  CTCGATTTCCTCTGCCTCTCTCTTTGCCGAGCTTTCCGCGACGGCCGCTCCGAGGACTTC
  CGCAGGACCCGCAACAGCGCAGAGGCTATTATTCATGGACTATCCAGTCTAACAGCTTGC
  CAGTTGAGAACGATATACATATGTCAGTTTTTGACAAGAATTGCAGCAGGAAAAACCCTT
  GATGCACAGTTTGAAAATGATGAACGAATTACACCCTTGGAATCAGCCCTGATGATTTGG
  GGTTCAATTGAAAAGGAACATGACAAACTTCATGAAGAAATACAGAATTTAATTAAAATT
  CAGGCTATAGCTGTTTGTATGGAAAATGGCAACTTTAAAGAAGCAGAAGAAGTCTTTGAA
  AGAATATTTGGTGATCCAAATTCTCATATGCCTTTCAAAAGCAAATTGCTTATGATAATC
  TCTCAGAAAGATACATTTCATTCCTTTTTTCAACACTTCAGCTACAACCACATGATGGAG
  AAAATTAAGAGTTATGTGAATTATGTGCTAAGTGAAAAATCATCAACCTTTCTAATGAAG
  GCAGCGGCAAAAGTAGTAGAAAGCAAAAGGACAAGAACAATAACTTCTCAAGATAAACCT
  AGTGGTAATGATGTTGAAATGGAAACTGAAGCTAATTTGGATACAAGAAAAAGTGTTAGT
  GACAAACAGTCTGCGGTAACTGAATCCTCAGAGGGTACAGTATCCTTATTGAGGTCTCAC
  AAGAATCTTTTCTTATCTAAGTTGCAACATGGAACCCAGCAACAAGACCTTAATAAGAAA
  GAAAGAAGAGTAGGAACTCCTCAAAGTACAAAAAAGAAAAAAGAAAGCAGAAGAGCCACT
  GAAAGCAGAATACCTGTTTCAAAGAGTCAGCCGGTAACTCCTGAAAAACATCGAGCTAGA
  AAAAGACAGGCATGGCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATAT
  GGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCGGACAAGTGTC
  ATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAA
  GACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATT
  TTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCATTACAGTATT
  TTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCAT
  TGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTA
  GTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATACGDAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_017489
• Insert Size: 1600 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_017489.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017489.1, NP_059523.1
• RefSeq Size: 2686 bp
• RefSeq ORF: 1320 bp
• Locus ID: 7013
• Cytogenetics: 8q21.11
• Domains: myb_DNA-binding
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).