DEPDC5 (NM_014662) Human Untagged Clone

CAT#: SC308914

DEPDC5 (untagged)-Human DEP domain containing 5 (DEPDC5), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEPDC5
• Synonyms: DEP.5; FFEVF; FFEVF1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014662, the custom clone sequence may differ by one or more nucleotides
  ATGAGAACAACAAAGGTCTACAAACTCGTCATCCACAAGAAGGGCTTTGGGGGCAGTGAT
  GATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAG
  ATTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAA
  GATTTACAGAAGGAAACTATCAGTGTGGACCAGACTGTGACTCAAGTGTTCCGGCTGAGA
  CCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTG
  GAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGT
  TTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGAGTTTGCTGGCATCAGAGCACAG
  GCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACC
  AGGGTGGTGTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAA
  ATGTGGGATTTTGATATTTATGGGGATTTGTATTTTGAGAAAGCTGTGAATGGTTTCCTT
  GCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTG
  TTTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCC
  TCAATTCGACAGGATCACAAGGGGAGATTCTATGAAGACTTTTACAAAGTGGTGGTGCAG
  AATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAG
  TATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACC
  TCAGCACAAGGAAACTACCTGGAGGCCATCAATCTGTCATTCAATGTGTTTGATAAGCAC
  TACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTG
  GGTGTCTTTGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAAT
  GGAATTGGTGTGGATTTGGTGTGCATGGGAGAGCAACCGTTACATGCTGTCCCATTGTTC
  AAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCT
  CACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACC
  CCACGAATAAAACTGGCAGGAAAGAAGCCCGCCTCTGAGAAAGCAAAAAATGGCCGTGAT
  ACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGAC
  GCCTATGACGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACC
  TGCAGATCTGTGCGAGAGCGAGAGAGTCACAGTCGAAAGAGTGCCAGCTCCTGTGATGTT
  TCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCT
  TCTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTG
  CACCAGTATGAAGTCAGCAGCTCCTTGGGATACACCAGCACTCGAGATGTCCTGGAGAAC
  ATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCA
  GAATCCATGCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCC
  TTCGCTCCCTCTCGGATGCCCATGAAGCTTACGTCCAACAGAAGGCGCTGGATGCACACT
  TTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATG
  GCGGAGCTACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAG
  TTAGCATATCATGAAGCTGCTGGAAGGCACAGCAATTCCCGCCAGCCTGGTGACGGCATG
  TCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGT
  GCAGGTATGAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCT
  CCAGACCCAATGCCAGGCTTCTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACT
  CCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCGCCAGGGCCTGCAGAATGAC
  TACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGAT
  GGTGTGCAGATGACAGCCCAGCAGGTATTTGAAGAGTTTATTTGCCAACGTCTCATGCAG
  GGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGCTGTCCCGCCCCCG
  CTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAG
  GACCAGTATTGGCTGAGTATGGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATG
  ATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGATCCACTACACC
  TACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCC
  CACGAACGGCTGGAGGAGTACAAGTGGAATTACTTAGATCAGTATATCTGTTCTGCCGGC
  TCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAGGACCCGCTTCCTGCTGCTG
  CCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTAT
  GGGGACAGGCCCCGTGCAGACGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGCTTT
  GTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGATGCGGAAAGGG
  ACCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACT
  GCACCCCCAGTGGGGAAGAAGGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCC
  AGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAG
  TCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGTA
  TCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCACCAGTTTGGGCATATGCACAGGC
  CAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAG
  GGCTACTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTG
  ACCTCATCCTCTACCCTGACAGAGATCCTGGAAGCCATGAAGCACCCCTCGACAGGAGTC
  CAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTA
  CACTGGTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATG
  CAGAAAATGCTGGAAGAGCAGCTCATCACACATGCATCTGGCGAAGCCTGGCGGACCTTC
  ATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGTGGCCATG
  CAGCAGCCCGCCACCACCTGGCACACAGCAGGAGTGGACGACTTCGCCAGCTTCCAGCGC
  AAGTGGTTTGAGGTGGCCTTTGTGGCAGAAGAGCTCGTGCACTCTGAGATTCCTGCCTTT
  CTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGC
  CGAAGTTTTGGAGGACGGAGCCAGGCGGCAGCACTTTTAGCTGCCACTGTCCCAGAGCAG
  AGGACTGTGACCCTGGATGTTGACGTGAACAACCGCACAGACCGGCTGGAGTGGTGCAGC
  TGTTATTACCATGGCAACTTTTCTCTGAATGCAGCCTTTGAGATCAAGCTGCACTGGATG
  GCGGTGACCGCAGCAGTACTCTTCGAGATGGTCCAAGGTTGGCATCGGAAAGCCACCTCC
  TGTGGCTTCTTGTTAGTCCCAGTTTTGGAGGGGCCTTTTGCACTGCCCAGTTACCTGTAT
  GGCGACCCCCTTCGTGCCCAGCTCTTCATCCCACTCAACATCAGCTGCTTGCTCAAGGAG
  GGCAGCGAGCACCTGTTTGATAGCTTTGAACCCGAAACGTACTGGGATCGAATGCACCTC
  TTCCAGGAAGCCATTGCACACAGGTTTGGGTTTGTACAAGATAAATATTCTGCCTCTGCT
  TTTAACTTCCCTGCTGAGAACAAGCCTCAGTATATCCACGTTACAGGAACAGTGTTTCTG
  CAGCTGCCCTACTCCAAGCGCAAGTTCTCAGGGCAGCAGCGGCGGCGGCGGAACTCCACC
  AGCTCCACCAACCAGAACATGTTCTGCGAGGAGCGGGTCGGCTACAACTGGGCCTACAAC
  ACCATGCTCACCAAAACATGGCGCTCCAGCGCCACAGGGGATGAAAAGTTTGCTGATCGG
  CTGCTGAAGGACTTCACGGACTTCTGCATCAACCGTGACAACCGGCTGGTCACGTTCTGG
  ACAAGTTGCCTGGAGAAGATGCATGCCAGTGCCCCGTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_014662
• ORF Size: 5316 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014662.2, NP_055477.1
• RefSeq Size: 5394
• RefSeq ORF: 5316
• Locus ID: 9681
• Domains: DEP
• Gene Summary: This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (1) uses an alternate in-frame splice site in an internal exon and lacks an in-frame exon in the 3' coding region compared to variant 4. The encoded protein (isoform 1) is shorter than isoform 4.