NuMA (NUMA1) (NM_006185) Human Untagged Clone

CAT#: SC308966

NUMA1 (untagged)-Human nuclear mitotic apparatus protein 1 (NUMA1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NUMA1
• Synonyms: NMP-22; NUMA
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006185, the custom clone sequence may differ by one or more nucleotides
  ATGACACTCCACGCCACCCGGGGGGCTGCACTCCTCTCTTGGGTGAACAGTCTACACGTG
  GCTGACCCTGTGGAGGCTGTGCTGCAGCTCCAGGACTGCAGCATCTTCATCAAGATCATT
  GACAGAATCCATGGCACTGAAGAGGGACAGCAAATCTTGAAGCAGCCGGTGTCAGAGAGA
  CTGGACTTTGTGTGCAGTTTTCTGCAGAAAAATCGAAAACATCCCTCTTCCCCAGAATGC
  CTGGTATCTGCACAGAAGGTGCTAGAGGGATCAGAGCTGGAACTGGCGAAGATGACCATG
  CTGCTCTTATACCACTCTACCATGAGCTCCAAAAGTCCCAGGGACTGGGAACAGTTTGAA
  TATAAAATTCAGGCTGAGTTGGCTGTCATTCTTAAATTTGTGCTGGACCATGAGGACGGG
  CTAAACCTTAATGAGGACCTAGAGAACTTCCTACAGAAAGCTCCTGTGCCTTCTACCTGT
  TCTAGCACATTCCCTGAAGAGCTCTCCCCACCTAGCCACCAGGCCAAGAGGGAGATTCGC
  TTCCTAGAGCTACAGAAGGTTGCCTCCTCTTCCAGTGGGAACAACTTTCTCTCAGGTTCT
  CCAGCTTCTCCCATGGGTGATATCCTGCAGACCCCACAGTTCCAGATGAGACGGCTGAAG
  AAGCAGCTTGCTGATGAGAGAAGTAATAGGGATGAGCTGGAGCTGGAGCTAGCTGAGAAC
  CGCAAGCTCCTCACCGAGAAGGATGCACAGATAGCCATGATGCAGCAGCGCATTGACCGC
  CTAGCCCTGCTGAATGAGAAGCAGGCGGCCAGCCCACTGGAGCCCAAGGAGCTTGAGGAG
  CTGCGTGACAAGAATGAGAGCCTTACCATGCGGCTGCATGAAACCCTGAAGCAGTGCCAG
  GACCTGAAGACAGAGAAGAGCCAGATGGATCGCAAAATCAACCAGCTTTCGGAGGAGAAT
  GGAGACCTTTCCTTTAAGCTGCGGGAGTTTGCCAGTCATCTGCAGCAGCTACAGGATGCC
  CTCAATGAGCTGACGGAGGAGCACAGCAAGGCCACTCAGGAGTGGCTAGAGAAGCAGGCC
  CAGCTGGAGAAGGAGCTCAGCGCAGCCCTGCAGGACAAGAAATGCCTTGAAGAGAAGAAC
  GAAATCCTTCAGGGAAAACTTTCACAGCTGGAAGAACACTTGTCCCAGCTGCAGGATAAC
  CCACCCCAGGAGAAGGGCGAGGTGCTGGGTGATGTCTTGCAGCTGGAAACCTTGAAGCAA
  GAGGCAGCCACTCTTGCTGCAAACAACACACAGCTCCAAGCCAGGGTAGAGATGCTGGAG
  ACTGAGCGAGGCCAGCAGGAAGCCAAGCTGCTTGCTGAGCGGGGCCACTTCGAAGAAGAA
  AAGCAGCAGCTGTCTAGCCTGATCACTGACCTGCAGAGCTCCATCTCCAACCTCAGCCAG
  GCCAAGGAAGAGCTGGAGCAGGCCTCCCAGGCTCATGGGGCCCGGTTGACTGCCCAGGTG
  GCCTCTCTGACCTCTGAGCTCACCACACTCAATGCCACCATCCAGCAACAGGATCAAGAA
  CTGGCTGGCCTGAAGCAGCAGGCCAAAGAGAAGCAGGCCCAGCTAGCACAGACCCTCCAA
  CAGCAAGAACAGGCCTCCCAGGGCCTCCGCCACCAGGTGGAGCAGCTAAGCAGTAGCCTG
  AAGCAGAAGGAGCAGCAGTTGAAGGAGGTAGCGGAGAAGCAGGAGGCAACTAGGCAGGAC
  CATGCCCAGCAACTGGCCACTGCTGCAGAGGAGCGAGAGGCCTCCTTAAGGGAGCGGGAT
  GCGGCTCTCAAGCAGCTGGAGGCACTGGAGAAGGAGAAGGCTGCCAAGCTGGAGATTCTG
  CAGCAGCAACTTCAGGTGGCTAATGAAGCCCGGGACAGTGCCCAGACCTCAGTGACACAG
  GCCCAGCGGGAGAAGGCAGAGCTGAGCCGGAAGGTGGAGGAACTCCAGGCCTGTGTTGAG
  ACAGCCCGCCAGGAACAGCATGAGGCCCAGGCCCAGGTTGCAGAGCTAGAGTTGCAGCTG
  CGGTCTGAGCAGCAAAAAGCAACTGAGAAAGAAAGGGTGGCCCAGGAGAAGGACCAGCTC
  CAGGAGCAGCTCCAGGCCCTCAAAGAGTCCTTGAAGGTCACCAAGGGCAGCCTTGAAGAG
  GAGAAGCGCAGGGCTGCAGATGCCCTGGAAGAGCAGCAGCGTTGTATCTCTGAGCTGAAG
  GCAGAGACCCGAAGCCTGGTGGAGCAGCATAAGCGGGAACGAAAGGAGCTGGAAGAAGAG
  AGGGCTGGGCGCAAGGGGCTGGAGGCTCGATTACAGCAGCTTGGGGAGGCCCATCAGGCT
  GAGACTGAAGTCCTGCGGCGGGAGCTGGCAGAGGCCATGGCTGCCCAGCACACAGCTGAG
  AGTGAGTGTGAGCAGCTCGTCAAAGAAGTAGCTGCCTGGCGTGAGCGGTATGAGGATAGC
  CAGCAAGAGGAGGCACAGTATGGCGCCATGTTCCAGGAACAGCTGATGACTTTGAAGGAG
  GAATGTGAGAAGGCCCGCCAGGAGCTGCAGGAGGCAAAGGAGAAGGTGGCAGGCATAGAA
  TCCCACAGCGAGCTCCAGATAAGCCGGCAGCAGAACGAACTAGCTGAGCTCCATGCCAAC
  CTGGCCAGAGCACTCCAGCAGGTCCAAGAGAAGGAAGTCAGGGCCCAGAAGCTTGCAGAT
  GACCTCTCCACTCTGCAGGAAAAGATGGCTGCCACCAGCAAAGAGGTGGCCCGCTTGGAG
  ACCTTGGTGCGCAAGGCAGGTGAGCAGCAGGAAACAGCCTCCCGGGAGTTAGTCAAGGAG
  CCTGCGAGGGCAGGAGACAGACAGCCCGAGTGGCTGGAAGAGCAACAGGGACGCCAGTTC
  TGCAGCACACAGGCAGCGCTGCAGGCTATGGAGCGGGAGGCAGAGCAGATGGGCAATGAG
  CTGGAACGGCTGCGGGCCGCGCTGATGGAGAGCCAGGGGCAGCAGCAGGAGGAGCGTGGG
  CAGCAGGAAAGGGAGGTGGCGCGGCTGACCCAGGAGCGGGGCCGTGCCCAGGCTGACCTT
  GCCCTGGAGAAGGCGGCCAGAGCAGAGCTTGAGATGCGGCTGCAGAACGCCCTCAACGAG
  CAGCGTGTGGAGTTCGCTACCCTGCAAGAGGCACTGGCTCATGCCCTGACGGAAAAGGAA
  GGCAAGGACCAGGAGTTGGCCAAGCTTCGTGGTCTGGAGGCAGCCCAGATAAAAGAGCTG
  GAGGAACTTCGGCAAACCGTGAAGCAACTGAAGGAACAGCTGGCTAAGAAAGAAAAGGAG
  CACGCATCTGGCTCAGGAGCCCAATCTGAGGCTGCTGGCAGGACAGAGCCAACAGGCCCC
  AAGCTGGAGGCACTGCGGGCAGAGGTGAGCAAGCTGGAACAGCAATGCCAGAAGCAGCAG
  GAGCAGGCTGACAGCCTGGAACGCAGCCTCGAGGCTGAGCGGGCCTCCCGGGCTGAGCGG
  GACAGTGCTCTGGAGACTCTGCAGGGCCAGTTAGAGGAGAAGGCCCAGGAGCTAGGGCAC
  AGTCAGAGTGCCTTAGCCTCGGCCCAACGGGAGTTGGCTGCCTTCCGCACCAAGGTACAA
  GACCACAGCAAGGCTGAAGATGAGTGGAAGGCCCAGGTGGCCCGGGGCCGGCAAGAGGCT
  GAGAGGAAAAATAGCCTCATCAGCAGCTTGGAGGAGGAGGTGTCCATCCTGAATCGCCAG
  GTCCTGGAGAAGGAGGGGGAGAGCAAGGAGTTGAAGCGGCTGGTGATGGCCGAGTCAGAG
  AAGAGCCAGAAGCTGGAGGAGAGGCTGCGCCTGCTGCAGGCAGAGACAGCCAGCAACAGT
  GCCAGAGCTGCAGAACGCAGCTCTGCTCTGCGGGAGGAGGTGCAGAGCCTCCGGGAGGAG
  GCTGAGAAACAGCGGGTGGCTTCAGAGAACCTGCGGCAGGAGCTGACCTCACAGGCTGAG
  CGTGCGGAGGAGCTGGGCCAAGAATTGAAGGCGTGGCAGGAGAAGTTCTTCCAGAAAGAG
  CAGGCCCTCTCCACCCTGCAGCTCGAGCACACCAGCACACAGGCCCTGGTGAGTGAGCTG
  CTGCCAGCTAAGCACCTCTGCCAGCAGCTGCAGGCCGAGCAGGCCGCTGCCGAGAAACGC
  CACCGTGAGGAGCTGGAGCAGAGCAAGCAGGCCGCTGGGGGACTGCGGGCAGAGCTGCTG
  CGGGCCCAGCGGGAGCTTGGGGAGCTGATTCCTCTGCGGCAGAAGGTGGCAGAGCAGGAG
  CGAACAGCTCAGCAGCTGCGGGCAGAGAAGGCCAGCTATGCAGAGCAGCTGAGCATGCTG
  AAGAAGGCGCATGGCCTGCTGGCAGAGGAGAACCGGGGGCTGGGTGAGCGGGCCAACCTT
  GGCCGGCAGTTTCTGGAAGTGGAGTTGGACCAGGCCCGGGAGAAGTATGTCCAAGAGTTG
  GCAGCCGTACGTGCTGATGCTGAGACCCGTCTGGCTGAGGTGCAGCGAGAAGCACAGAGC
  ACTGCCCGGGAGCTGGAGGTGATGACTGCCAAGTATGAGGGTGCCAAGGTCAAGGTCCTG
  GAGGAGAGGCAGCGGTTCCAGGAAGAGAGGCAGAAACTCACTGCCCAGGTGGAGCAGCTA
  GAGGTATTTCAGAGAGAGCAAACTAAGCAGGTGGAAGAACTGAGTAAGAAACTGGCTGAC
  TCTGACCAAGCCAGCAAGGTGCAGCAGCAGAAGCTGAAGGCTGTCCAGGCTCAGGGAGGC
  GAGAGCCAGCAGGAGGCCCAGCGCCTCCAGGCCCAGCTGAATGAACTGCAAGCCCAGTTG
  AGCCAGAAGGAGCAGGCAGCTGAGCACTATAAGCTGCAGATGGAGAAAGCCAAAACACAT
  TATGATGCCAAGAAGCAGCAGAACCAAGAGCTGCAGGAGCAGCTGCGGAGCCTGGAGCAG
  CTGCAGAAGGAAAACAAAGAGCTGCGAGCTGAAGCTGAACGGCTGGGCCATGAGCTACAG
  CAGGCTGGGCTGAAGACCAAGGAGGCTGAACAGACCTGCCGCCACCTTACTGCCCAGGTG
  CGCAGCCTGGAGGCACAGGTTGCCCATGCAGACCAGCAGCTTCGAGACCTGGGCAAATTC
  CAGGTGGCAACTGATGCTTTAAAGAGCCGTGAGCCCCAGGCTAAGCCCCAGCTGGACTTG
  AGTATTGACAGCCTGGATCTGAGCTGCGAGGAGGGGACCCCACTCAGTATCACCAGCAAG
  CTGCCTCGTACCCAGCCAGACGGCACCAGCGTCCCTGGAGAACCAGCCTCACCTATCTCC
  CAGCGCCTGCCCCCCAAGGTAGAATCCCTGGAGAGTCTCTACTTCACTCCCATCCCTGCT
  CGGAGTCAGGCCCCCCTGGAGAGCAGCCTGGACTCCCTGGGAGACGTCTTCCTGGACTCG
  GGTCGTAAGACCCGCTCCGCTCGTCGGCGCACCACGCAGATCATCAACATCACCATGACC
  AAGAAGCTAGATGTGGAAGAGCCAGACAGCGCCAACTCATCGTTCTACAGCACGCGGTCT
  GCTCCTGCTTCCCAGGCTAGCCTGCGAGCCACCTCCTCTACTCAGTCTCTAGCTCGCCTG
  GGTTCTCCCGATTATGGCAACTCAGCCCTGCTCAGCTTGCCTGGCTACCGCCCCACCACT
  CGCAGTTCTGCTCGTCGTTCCCAGGCCGGGGTGTCCAGTGGGGCCCCTCCAGGAAGGAAC
  AGCTTCTACATGGGCACTTGCCAGGATGAGCCTGAGCAGCTGGATGACTGGAACCGCATT
  GCAGAGCTGCAGCAGCGCAATCGAGTGTGCCCCCCACATCTGAAGACCTGCTATCCCCTG
  GAGTCCAGGCCTTCCCTGAGCCTGGGCACCATCACAGATGAGGAGATGAAAACTGGAGAC
  CCCCAAGAGACCCTGCGCCGAGCCAGCATGCAGCCAATCCAGATAGCCGAGGGCACTGGC
  ATCACCACCCGGCAGCAGCGCAAACGGGTCTCCCTAGAGCCCCACCAGGGCCCTGGAACT
  CCTGAGTCTAAGAAGGCCACCAGCTGTTTCCCACGCCCCATGACTCCCCGAGACCGACAT
  GAAGGGCGCAAACAGAGCACTACTGAGGCCCAGAAGAAAGCAGCTCCAGCTTCTACTAAA
  CAGGCTGACCGGCGCCAGTCGATGGCCTTCAGCATCCTCAACACACCCAAGAAGCTAGGG
  AACAGCCTTCTGCGGCGGGGAGCCTCAAAGAAGGCCCTGTCCAAGGCTTCCCCCAACACT
  CGCAGTGGAACCCGCCGTTCTCCGCGCATTGCCACCACCACAGCCAGCGCCGCCACTGCT
  GCCGCCATTGGTGCCACCCCTCGAGCCAAGGGCAAGGCAAAGCACTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_006185
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006185.2, NP_006176.2
• RefSeq Size: 7182 bp
• RefSeq ORF: 6348 bp
• Locus ID: 4926
• Cytogenetics: 11q13.4
• Domains: M
• Gene Summary: 'This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).