MRP6 (ABCC6) (NM_001171) Human Untagged Clone

CAT#: SC309046

ABCC6 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1


  "NM_001171" in other vectors (6)

Reconstitution Protocol

USD 3,050.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ABCC6
Synonyms ABC34; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001171 edited
ACCCACGACGACAGAAGGCGCCGATGGCCGCGCCTGCTGAGCCCTGCGCGGGGCAGGGGG
TCTGGAACCAGACAGAGCCTGAACCTGCCGCCACCAGCCTGCTGAGCCTGTGCTTCCTGA
GAACAGCAGGGGTCTGGGTACCCCCCATGTACCTCTGGGTCCTTGGTCCCATCTACCTCC
TCTTCATCCACCACCATGGCCGGGGCTACCTCCGGATGTCCCCACTCTTCAAAGCCAAGA
TGGTGCTTGGATTCGCCCTCATAGTCCTGTGTACCTCCAGCGTGGCTGTCGCTCTTTGGA
AAATCCAACAGGGAACGCCTGAGGCCCCAGAATTCCTCATTCATCCTACTGTGTGGCTCA
CCACGATGAGCTTCGCAGTGTTCCTGATTCACACCGAGAGGAAAAAGGGAGTCCAGTCAT
CTGGAGTGCTGTTTGGTTACTGGCTTCTCTGCTTTGTCTTGCCAGCTACCAACGCTGCCC
AGCAGGCCTCCGGAGCGGGCTTCCAGAGCGACCCTGTCCGCCACCTGTCCACCTACCTAT
GCCTGTCTCTGGTGGTGGCACAGTTTGTGCTGTCCTGCCTGGCGGATCAACCCCCCTTCT
TCCCTGAAGACCCCCAGCAGTCTAACCCCTGTCCAGAGACTGGGGCAGCCTTCCCCTCCA
AAGCCACGTTCTGGTGGGTTTCTGGCCTGGTCTGGAGGGGATACAGGAGGCCACTGAGAC
CAAAAGACCTCTGGTCGCTTGGGAGAGAAAACTCCTCAGAAGAACTTGTTTCCCGGCTTG
AAAAGGAGTGGATGAGGAACCGCAGTGCAGCCCGGAGGCACAACAAGGCAATAGCATTTA
AAAGGAAAGGCGGCAGTGGCATGAAGGCTCCAGAGACCGAGCCCTTCCTACGGCAAGAAG
GGAGCCAGTGGCGCCCACTGCTGAAGGCCATCTGGCAGGTGTTCCATTCTACCTTCCTCC
TGGGGACCCTCAGCCTCATCATCAGTGATGTCTTCAGGTTCACTGTCCCCAAGCTGCTCA
GCCTTTTCCTGGAGTTTATTGGTGATCCCAAGCCTCCAGCCTGGAAGGGCTACCTCCTCG
CCGTGCTGATGTTCCTCTCAGCCTGCCTGCAAACGCTGTTTGAGCAGCAGAACATGTACA
GGCTCAAGGTGCTGCAGATGAGGTTGCGGTCGGCCATCACTGGCCTGGTGTACAGAAAGG
TCCTGGCTCTGTCCAGCGGCTCCAGAAAGGCCAGTGCGGTGGGTGATGTGGTCAATCTGG
TGTCCGTGGACGTGCAGCGGCTGACCGAGAGCGTCCTCTACCTCAACGGGCTGTGGCTGC
CTCTCGTCTGGATCGTGGTCTGCTTCGTCTATCTCTGGCAGCTCCTGGGGCCCTCCGCCC
TCACTGCCATCGCTGTCTTCCTGAGCCTCCTCCCTCTGAATTTCTTCATCTCCAAGAAAA
GGAACCACCATCAGGAGGAGCAAATGAGGCAGAAGGACTCACGGGCACGGCTCACCAGCT
CTATCCTCAGGAACTCGAAGACCATCAAGTTCCATGGCTGGGAGGGAGCCTTTCTGGACA
GAGTCCTGGGCATCCGAGGCCAGGAGCTGGGCGCCTTGCGGACCTCCGGCCTCCTCTTCT
CTGTGTCGCTGGTGTCCTTCCAAGTGTCTACATTTCTGGTCGCACTGGTGGTGTTTGCTG
TCCACACTCTGGTGGCCGAGAATGCTATGAATGCAGAGAAAGCCTTTGTGACTCTCACAG
TTCTCAACATCCTCAACAAGGCCCAGGCTTTCCTGCCCTTCTCCATCCACTCCCTCGTCC
AGGCCCGGGTGTCCTTTGACCGTCTGGTCACCTTCCTCTGCCTGGAAGAAGTTGACCCTG
GTGCCGTAGACTCAAGTTCCTCTGGAAGCGCTGCCGGGAAGGATTGCATCACGATACAAA
GTGCCACCTTCGCCTGGTCCCAGGAAAGCCCTCCCTGCCTCCACAGAATAAACCTCACGG
TGCCCCAGGGCTGTCTGCTGGCTGTTGTCGGTCCAGTGGGGGCAGGGAAGTCCTCCCTGC
TGTCCGCCCTCCTTGGGGAGCTGTCAAAGGTGGAGGGGTTCGTGAGCATCGAGGGTGCTG
TGGCCTACGTGCCCCAGGAGGCCTGGGTGCAGAACACCTCTGTGGTAGAGAATGTGTGCT
TCGGGCAGGAGCTGGACCCACCCTGGCTGGAGAGAGTACTAGAAGCCTGTGCCCTGCAGC
CAGATGTGGACAGCTTCCCTGAGGGAATCCACACTTCAATTGGGGAGCAGGGCATGAATC
TCTCCGGAGGCCAGAAGCAGCGGCTGAGCCTGGCCCGGGCTGTATACAGAAAGGCAGCTG
TGTACCTGCTGGATGACCCCCTGGCGGCCCTGGATGCCCACGTTGGCCAGCATGTCTTCA
ACCAGGTCATTGGGCCTGGTGGGCTACTCCAGGGAACAACACGGATTCTCGTGACGCACG
CACTCCACATCCTGCCCCAGGCTGATTGGATCATAGTGCTGGCAAATGGGGCCATCGCAG
AGATGGGTTCCTACCAGGAGCTTCTGCAGAGGAAGGGGGCCCTCGTGTGTCTTCTGGATC
AAGCCAGACAGCCAGGAGATAGAGGAGAAGGAGAAACAGAACCTGGGACCAGCACCAAGG
ACCCCAGAGGCACCTCTGCAGGCAGGAGGCCCGAGCTTAGACGCGAGAGGTCCATCAAGT
CAGTCCCTGAGAAGGACCGTACCACTTCAGAAGCCCAGACAGAGGTTCCTCTGGATGACC
CTGACAGGGCAGGATGGCCAGCAGGAAAGGACAGCATCCAATACGGCAGGGTGAAGGCCA
CAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCC
TCTTCCTCTGCCAGCAAGTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGG
ACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGCGGGATCTTCGGGC
TCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTG
GGGCCCGGGCATCCAGGTTGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCA
TCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCTCCAAGGAGACAG
ACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGAC
TCCTGGAGGTCAGCCTGGTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGC
CACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCTCATGCCAGCTGA
GACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGG
GCAGCACAGTGGTCCGGGCATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTC
GCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGACAGGTGGCTTGCGG
CCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGA
GCAAAGCCCACCTCAGTGCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGA
CCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACAGCATCGTGTCAG
TGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACAT
GTGCAGCTCAGCCCCCCTGGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAA
GATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAGATCCACGCAGGAG
AGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGC
TGCGGCTCCAGGAGGCAGCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACG
TGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACCCCATCCTGTTCC
CTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGG
CAGCCCTGGAGACGGTGCAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGT
ACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAGCTCCTGTGTCTGG
CACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGG
ACCCTGGCACGGAGCTGCAGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTG
TGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGGTTCTGGTCATGG
ACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGT
TTTACAGACTGGCCCAGGAGTCAGGCCTGGTCTGA
Restriction Sites Please inquire     
ACCN NM_001171
Insert Size 4500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The ORF of this clone has been fully sequenced and found to contain a number of SNPs compared with NM_001171.2.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001171.2, NP_001162.2
RefSeq Size 4535 bp
RefSeq ORF 4512 bp
Locus ID 368
Cytogenetics 16p13.11
Domains ABC_membrane, ABC_tran, AAA
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
Gene Summary 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) encodes the longest isoform (1).

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