MRP6 (ABCC6) (NM_001171) Human Untagged Clone

CAT#: SC309046

ABCC6 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCC6
• Synonyms: ABC34; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001171 edited
  ACCCACGACGACAGAAGGCGCCGATGGCCGCGCCTGCTGAGCCCTGCGCGGGGCAGGGGG
  TCTGGAACCAGACAGAGCCTGAACCTGCCGCCACCAGCCTGCTGAGCCTGTGCTTCCTGA
  GAACAGCAGGGGTCTGGGTACCCCCCATGTACCTCTGGGTCCTTGGTCCCATCTACCTCC
  TCTTCATCCACCACCATGGCCGGGGCTACCTCCGGATGTCCCCACTCTTCAAAGCCAAGA
  TGGTGCTTGGATTCGCCCTCATAGTCCTGTGTACCTCCAGCGTGGCTGTCGCTCTTTGGA
  AAATCCAACAGGGAACGCCTGAGGCCCCAGAATTCCTCATTCATCCTACTGTGTGGCTCA
  CCACGATGAGCTTCGCAGTGTTCCTGATTCACACCGAGAGGAAAAAGGGAGTCCAGTCAT
  CTGGAGTGCTGTTTGGTTACTGGCTTCTCTGCTTTGTCTTGCCAGCTACCAACGCTGCCC
  AGCAGGCCTCCGGAGCGGGCTTCCAGAGCGACCCTGTCCGCCACCTGTCCACCTACCTAT
  GCCTGTCTCTGGTGGTGGCACAGTTTGTGCTGTCCTGCCTGGCGGATCAACCCCCCTTCT
  TCCCTGAAGACCCCCAGCAGTCTAACCCCTGTCCAGAGACTGGGGCAGCCTTCCCCTCCA
  AAGCCACGTTCTGGTGGGTTTCTGGCCTGGTCTGGAGGGGATACAGGAGGCCACTGAGAC
  CAAAAGACCTCTGGTCGCTTGGGAGAGAAAACTCCTCAGAAGAACTTGTTTCCCGGCTTG
  AAAAGGAGTGGATGAGGAACCGCAGTGCAGCCCGGAGGCACAACAAGGCAATAGCATTTA
  AAAGGAAAGGCGGCAGTGGCATGAAGGCTCCAGAGACCGAGCCCTTCCTACGGCAAGAAG
  GGAGCCAGTGGCGCCCACTGCTGAAGGCCATCTGGCAGGTGTTCCATTCTACCTTCCTCC
  TGGGGACCCTCAGCCTCATCATCAGTGATGTCTTCAGGTTCACTGTCCCCAAGCTGCTCA
  GCCTTTTCCTGGAGTTTATTGGTGATCCCAAGCCTCCAGCCTGGAAGGGCTACCTCCTCG
  CCGTGCTGATGTTCCTCTCAGCCTGCCTGCAAACGCTGTTTGAGCAGCAGAACATGTACA
  GGCTCAAGGTGCTGCAGATGAGGTTGCGGTCGGCCATCACTGGCCTGGTGTACAGAAAGG
  TCCTGGCTCTGTCCAGCGGCTCCAGAAAGGCCAGTGCGGTGGGTGATGTGGTCAATCTGG
  TGTCCGTGGACGTGCAGCGGCTGACCGAGAGCGTCCTCTACCTCAACGGGCTGTGGCTGC
  CTCTCGTCTGGATCGTGGTCTGCTTCGTCTATCTCTGGCAGCTCCTGGGGCCCTCCGCCC
  TCACTGCCATCGCTGTCTTCCTGAGCCTCCTCCCTCTGAATTTCTTCATCTCCAAGAAAA
  GGAACCACCATCAGGAGGAGCAAATGAGGCAGAAGGACTCACGGGCACGGCTCACCAGCT
  CTATCCTCAGGAACTCGAAGACCATCAAGTTCCATGGCTGGGAGGGAGCCTTTCTGGACA
  GAGTCCTGGGCATCCGAGGCCAGGAGCTGGGCGCCTTGCGGACCTCCGGCCTCCTCTTCT
  CTGTGTCGCTGGTGTCCTTCCAAGTGTCTACATTTCTGGTCGCACTGGTGGTGTTTGCTG
  TCCACACTCTGGTGGCCGAGAATGCTATGAATGCAGAGAAAGCCTTTGTGACTCTCACAG
  TTCTCAACATCCTCAACAAGGCCCAGGCTTTCCTGCCCTTCTCCATCCACTCCCTCGTCC
  AGGCCCGGGTGTCCTTTGACCGTCTGGTCACCTTCCTCTGCCTGGAAGAAGTTGACCCTG
  GTGCCGTAGACTCAAGTTCCTCTGGAAGCGCTGCCGGGAAGGATTGCATCACGATACAAA
  GTGCCACCTTCGCCTGGTCCCAGGAAAGCCCTCCCTGCCTCCACAGAATAAACCTCACGG
  TGCCCCAGGGCTGTCTGCTGGCTGTTGTCGGTCCAGTGGGGGCAGGGAAGTCCTCCCTGC
  TGTCCGCCCTCCTTGGGGAGCTGTCAAAGGTGGAGGGGTTCGTGAGCATCGAGGGTGCTG
  TGGCCTACGTGCCCCAGGAGGCCTGGGTGCAGAACACCTCTGTGGTAGAGAATGTGTGCT
  TCGGGCAGGAGCTGGACCCACCCTGGCTGGAGAGAGTACTAGAAGCCTGTGCCCTGCAGC
  CAGATGTGGACAGCTTCCCTGAGGGAATCCACACTTCAATTGGGGAGCAGGGCATGAATC
  TCTCCGGAGGCCAGAAGCAGCGGCTGAGCCTGGCCCGGGCTGTATACAGAAAGGCAGCTG
  TGTACCTGCTGGATGACCCCCTGGCGGCCCTGGATGCCCACGTTGGCCAGCATGTCTTCA
  ACCAGGTCATTGGGCCTGGTGGGCTACTCCAGGGAACAACACGGATTCTCGTGACGCACG
  CACTCCACATCCTGCCCCAGGCTGATTGGATCATAGTGCTGGCAAATGGGGCCATCGCAG
  AGATGGGTTCCTACCAGGAGCTTCTGCAGAGGAAGGGGGCCCTCGTGTGTCTTCTGGATC
  AAGCCAGACAGCCAGGAGATAGAGGAGAAGGAGAAACAGAACCTGGGACCAGCACCAAGG
  ACCCCAGAGGCACCTCTGCAGGCAGGAGGCCCGAGCTTAGACGCGAGAGGTCCATCAAGT
  CAGTCCCTGAGAAGGACCGTACCACTTCAGAAGCCCAGACAGAGGTTCCTCTGGATGACC
  CTGACAGGGCAGGATGGCCAGCAGGAAAGGACAGCATCCAATACGGCAGGGTGAAGGCCA
  CAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCC
  TCTTCCTCTGCCAGCAAGTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGG
  ACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGCGGGATCTTCGGGC
  TCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTG
  GGGCCCGGGCATCCAGGTTGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCA
  TCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCTCCAAGGAGACAG
  ACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGAC
  TCCTGGAGGTCAGCCTGGTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGC
  CACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCTCATGCCAGCTGA
  GACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGG
  GCAGCACAGTGGTCCGGGCATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTC
  GCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGACAGGTGGCTTGCGG
  CCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGA
  GCAAAGCCCACCTCAGTGCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGA
  CCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACAGCATCGTGTCAG
  TGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACAT
  GTGCAGCTCAGCCCCCCTGGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAA
  GATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAGATCCACGCAGGAG
  AGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGC
  TGCGGCTCCAGGAGGCAGCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACG
  TGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACCCCATCCTGTTCC
  CTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGG
  CAGCCCTGGAGACGGTGCAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGT
  ACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAGCTCCTGTGTCTGG
  CACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGG
  ACCCTGGCACGGAGCTGCAGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTG
  TGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGGTTCTGGTCATGG
  ACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGT
  TTTACAGACTGGCCCAGGAGTCAGGCCTGGTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001171
• Insert Size: 4500 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain a number of SNPs compared with NM_001171.2.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001171.2, NP_001162.2
• RefSeq Size: 4535 bp
• RefSeq ORF: 4512 bp
• Locus ID: 368
• Cytogenetics: 16p13.11
• Domains: ABC_membrane, ABC_tran, AAA
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).