Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (NM_000748) Human Untagged Clone

CAT#: SC309051

CHRNB2 (untagged)-Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHRNB2
• Synonyms: EFNL3; nAChRB2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000748 edited
  CCCAGGAACCACCGCGGCGGCCGGCACCACCTGGACCCAGCTCCAGGCGGGCGCGGCTTC
  AGCACCACGGACAGCGCCCCACCCGCGGCCCTCCCCCCGGCGGCGCGCTCCAGCCGGTGT
  AGGCGAGGCAGCGAGCTATGCCCGCGGCATGGCCCGGCGCTGCGGCCCCGTGGCGCTGCT
  CCTTGGCTTCGGCCTCCTCCGGCTGTGCTCAGGGGTGTGGGGTACGGATACAGAGGAGCG
  GCTGGTGGAGCATCTCCTGGATCCTTCCCGCTACAACAAGCTTATCCGCCCAGCCACCAA
  TGGCTCTGAGCTGGTGACAGTACAGCTTATGGTGTCACTGGCCCAGCTCATCAGTGTGCA
  TGAGCGGGAGCAGATCATGACCACCAATGTCTGGCTGACCCAGGAGTGGGAAGATTATCG
  CCTCACCTGGAAGCCTGAAGAGTTTGACAACATGAAGAAAGTTCGGCTCCCTTCCAAACA
  CATCTGGCTCCCAGATGTGGTCCTGTACAACAATGCTGACGGCATGTACGAGGTGTCCTT
  CTATTCCAATGCCGTGGTCTCCTATGATGGCAGCATCTTCTGGCTGCCGCCTGCCATCTA
  CAAGAGCGCATGCAAGATTGAAGTAAAGCACTTCCCATTTGACCAGCAGAACTGCACCAT
  GAAGTTCCGTTCGTGGACCTACGACCGCACAGAGATCGACTTGGTGCTGAAGAGTGAGGT
  GGCCAGCCTGGACGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCGGGCCG
  GCGCAACGAGAACCCCGACGACTCTACGTACGTGGACATCACGTATGACTTCATCATTCG
  CCGCAAGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGTGTGCTCATCACCTCGCT
  AGCCATCCTTGTCTTCTACCTGCCATCCGACTGTGGCGAGAAGATGACGTTGTGCATCTC
  AGTGCTGCTGGCGCTCACGGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCTCCCACCTC
  CCTCGACGTGCCGCTCGTCGGCAAGTACCTCATGTTCACCATGGTGCTTGTCACCTTCTC
  CATCGTCACCAGCGTGTGCGTGCTCAACGTGCACCACCGCTCGCCCACCACGCACACCAT
  GGCGCCCTGGGTGAAGGTCGTCTTCCTGGAGAAGCTGCCCGCGCTGCTCTTCATGCAGCA
  GCCACGCCATCATTGCGCCCGTCAGCGCCTGCGCCTGCGGCGACGCCAGCGTGAGCGCGA
  GGGCGCTGGAGCCCTCTTCTTCCGCGAAGCCCCAGGGGCCGACTCCTGCACGTGCTTCGT
  CAACCGCGCGTCGGTGCAGGGGTTGGCCGGGGCCTTCGGGGCTGAGCCTGCACCAGTGGC
  GGGCCCCGGGCGCTCAGGGGAGCCGTGTGGCTGTGGCCTCCGGGAGGCGGTGGACGGCGT
  GCGCTTCATCGCAGACCACATGCGGAGCGAGGACGATGACCAGAGCGTGAGTGAGGACTG
  GAAGTACGTCGCCATGGTGATCGACCGCCTCTTCCTCTGGATCTTTGTCTTTGTCTGTGT
  CTTTGGCACCATCGGCATGTTCCTGCAGCCTCTCTTCCAGAACTACACCACCACCACCTT
  CCTCCACTCAGACCACTCAGCCCCCAGCTCCAAGTGAGGCCCTTCCTCATCTCCATGCTC
  TTTCTCGAGCGGAAGGGCGAATTCAGATCTGGTACCGATATCAAGCTTGTCGACTCTAGA
  TTGCGGCCGCGGTCATAGCTGTTTC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000748 unedited
  GGGGGTGTTCAGATATTTGTAAACGACTTACTATAGGGNNCGGCCGCGCAATTCCTCATA
  CCAGGATAGGCAAGAAGCTGGTTTCTCCTCGCAGCCGGCTCCCTGAGGCCCAGGAACCAC
  CGCGGCGGCCGGCACCACCTGGACCCAGCTCCAGGCGGGCGCGGCTTCAGCACCACGGAC
  AGCGCCCCACCCGCGGCCCTCCCCCCGGCGGCGCGCTCCAGCCGGTGTAGGCGAGGCAGC
  GAGCTATGCCCGCGGCATGGCCCGGCGCTGCGGCCCCGTGGCGCTGCTCCTTGGCTTCGG
  CCTCCTCCGGCTGTGCTCAGGGGTGTGGGGTACGGATACAGAGGAGCGGCTGGTGGAGCA
  TCTCCTGGATCCTTCCCGCTACAACAAGCTTATCCGCCCAGCCACCAATGGCTCTGAGCT
  GGTGACAGTACAGCTTATGGTGTCACTGGCCCAGCTCATCAGTGTGCATGAGCGGGAGCA
  GATCATGACCACCAATGTCTGGCTGACCCAGGAGTGGGAAGATTATCGCCTCACCTGGAA
  GCCTGAAGAGTTTGACAACATGAAGAAAGTTCGGCTCCCTTCCAAACACATCTGGCTCCC
  AGATGTGGTCCTGTACAACAATGCTGACGGCATGTACGAGGTGTCCTTCTATTCCAATGC
  CGTGGTCTCCTATGATGGCAGCATCTTCTGGCTGCCGCCTGCCATCTACAAGAGCGCATG
  CAAGATTGAAGTAAAGCACTTCCCATTTGACCAGCAGAACTGCACCATGAAGTTCCGTTC
  GTGGACCTACGACCGCACAGAGATCGACTTGGTGCTGAAGAGTGAGGTGGCCAGCCTGGA
  CGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCGGGCCGGCGCAACGAGAA
  CCCCGACGACTCTACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000748 unedited
  CTGGGAGGCACTTCAGGCCAGAGAGATGGGAGGGTCACAGGGTGCCCCCGGGATCGTTCA
  GAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATATCGGTACCAGATC
  TGAATTCGCCCTTCCGCTCGAGAAAGAGCATGGAGATGAGGAAGGGCCTCACTTGGAGCT
  GGGGGCTGAGTGGTCTGAGTGGAGGAAGGTGGTGGTGGTGTAGTTCTGGAAGAGAGGCTG
  CAGGAACATGCCGATGGTGCCAAAGACACAGACAAAGACAAAGATCCAGAGGAAGAGGCG
  GTCGATCACCATGGCGACGTACTTCCAGTCCTCACTCACGCTCTGGTCATCGTCCTCGCT
  CCGCATGTGGTCTGCGATGAAGCGCACGCCGTCCACCGCCTCCCGGAGGCCACAGCCACA
  CGGCTCCCCTGAGCGCCCGGGGCCCGCCACTGGTGCAGGCTCAGCCCCGAAGGCCCCGGC
  CAACCCCTGCACCGACGCGCGGTTGACGAAGCACGTGCAGGAGTCAGCCCCTGGGGCTTC
  GCGGAAGAAGAGGGCTCCAGCGCCCTCGCGCTCACGCTGGCGTCGCCGCAGGCGCAAGCG
  CTGACGGGCGCAATGATGGCGTGGCTGCTGCATGAAGAGCAGCGCGGGCAGCTTCTCCAG
  GAAGACGACCTTCACCCATGGCGCCATGGTGTGGCTTGGTGGCCGACCGGTGGTGCACGT
  TTAAGCCGCCCCACGCTGGTGACCAATGGAGAAGGTGACCAAGCCCCATGGTGGACATTG
  AGGTAACTTGCCGCCCAAGCGGCACGTCCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_000748
• ORF Size: 1509 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_000748.1, NP_000739.1
• RefSeq Size: 2448
• RefSeq ORF: 1509
• Locus ID: 1141
• Domains: Neur_chan_memb, Neur_chan_LBD
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Gene Summary: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]