COL11A1 (NM_080630) Human Untagged Clone

CAT#: SC309082

COL11A1 (untagged)-Human collagen, type XI, alpha 1 (COL11A1), transcript variant C

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COL11A1
• Synonyms: CO11A1; COLL6; STL2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_080630, the custom clone sequence may differ by one or more nucleotides
  ATGGAGCCGTGGTCCTCTAGGTGGAAAACGAAACGGTGGCTCTGGGATTTCACCGTAACA
  ACCCTCGCATTGACCTTCCTCTTCCAAGCTAGAGAGGTCAGAGGAGCTGCTCCAGTTGAT
  GTACTAAAAGCACTAGATTTTCACAATTCTCCAGAGGGAATATCAAAAACAACGGGATTT
  TGCACAAACAGAAAGAATTCTAAAGGCTCAGATACTGCTTACAGAGTTTCAAAGCAAGCA
  CAACTCAGTGCCCCAACAAAACAGTTATTTCCAGGTGGAACTTTCCCAGAAGACTTTTCA
  ATACTATTTACAGTAAAACCAAAAAAAGGAATTCAGTCTTTCCTTTTATCTATATATAAT
  GAGCATGGTATTCAGCAAATTGGTGTTGAGGTTGGGAGATCACCTGTTTTTCTGTTTGAA
  GACCACACTGGAAAACCTGCCCCAGAAGACTATCCCCTCTTCAGAACTGTTAACATCGCT
  GACGGGAAGTGGCATCGGGTAGCAATCAGCGTGGAGAAGAAAACTGTGACAATGATTGTT
  GATTGTAAGAAGAAAACCACGAAACCACTTGATAGAAGTGAGAGAGCAATTGTTGATACC
  AATGGAATCACGGTTTTTGGAACAAGGATTTTGGATGAAGAAGTTTTTGAGGGGGACATT
  CAGCAGTTTTTGATCACAGGTGATCCCAAGGCAGCATATGACTACTGTGAGCATTATAGT
  CCAGACTGTGACTCTTCAGCACCCAAGGCTGCTCAAGCTCAGGAACCTCAGATAGATGAG
  GCAAACATCGTTGATGATTTTCAAGAATACAACTATGGAACAATGGAAAGTTACCAGACA
  GAAGCTCCTAGGCATGTTTCTGGGACAAATGAGCCAAATCCAGTTGAAGAAATATTTACT
  GAAGAATATCTAACGGGAGAGGATTATGATTCCCAGAGGAAAAATTCTGAGGATACACTA
  TATGAAAACAAAGAAATAGACGGCAGGGATTCTGATCTTCTGGTAGATGGAGATTTAGGC
  GAATATGATTTTTATGAATATAAAGAATATGAAGATAAACCAACAAGCCCCCCTAATGAA
  GAATTTGGTCCAGGTGTACCAGCAGAAACTGATATTACAGAAACAAGCATAAATGGCCAT
  GGTGCATATGGAGAGAAAGGACAGAAAGGAGAACCAGCAGTGGTTGAGCCTGGTATGCTT
  GTCGAAGGACCACCAGGACCAGCAGGACCTGCAGGTATTATGGGTCCTCCAGGTCTACAA
  GGCCCCACTGGACCCCCTGGTGACCCTGGCGATAGGGGCCCCCCAGGACGTCCTGGCTTA
  CCAGGGGCTGATGGTCTACCTGGTCCTCCTGGTACTATGTTGATGTTACCGTTCCGTTAT
  GGTGGTGATGGTTCCAAAGGACCAACCATCTCTGCTCAGGAAGCTCAGGCTCAAGCTATT
  CTTCAGCAGGCTCGGATTGCTCTGAGAGGCCCACCTGGCCCAATGGGTCTAACTGGAAGA
  CCAGGTCCTGTGGGGGGGCCTGGTTCATCTGGGGCCAAAGGTGAGAGTGGTGATCCAGGT
  CCTCAGGGCCCTCGAGGCGTCCAGGGTCCCCCTGGTCCAACGGGAAAACCTGGAAAAAGG
  GGTCGTCCAGGTGCAGATGGAGGAAGAGGAATGCCAGGAGAACCTGGGGCAAAGGGAGAT
  CGAGGGTTTGATGGACTTCCGGGTCTGCCAGGTGACAAAGGTCACAGGGGTGAACGAGGT
  CCTCAAGGTCCTCCAGGTCCTCCTGGTGATGATGGAATGAGGGGAGAAGATGGAGAAATT
  GGACCAAGAGGTCTTCCAGGTGAAGCTGGCCCACGAGGTTTGCTGGGTCCAAGGGGAACT
  CCAGGAGCTCCAGGGCAGCCTGGTATGGCAGGTGTAGATGGCCCCCCAGGACCAAAAGGG
  AACATGGGTCCCCAAGGGGAGCCTGGGCCTCCAGGTCAACAAGGGAATCCAGGACCTCAG
  GGTCTTCCTGGTCCACAAGGTCCAATTGGTCCTCCTGGTGAAAAAGGACCACAAGGAAAA
  CCAGGACTTGCTGGACTTCCTGGTGCTGATGGGCCTCCTGGTCATCCTGGGAAAGAAGGC
  CAGTCTGGAGAAAAGGGGGCTCTGGGTCCCCCTGGTCCACAAGGTCCTATTGGATACCCG
  GGCCCCCGGGGAGTAAAGGGAGCAGATGGTGTCAGAGGTCTCAAGGGATCTAAAGGTGAA
  AAGGGTGAAGATGGTTTTCCAGGATTCAAAGGTGACATGGGTCTAAAAGGTGACAGAGGA
  GAAGTTGGTCAAATTGGCCCAAGAGGGGAAGATGGCCCTGAAGGACCCAAAGGTCGAGCA
  GGCCCAACTGGAGACCCAGGTCCTTCAGGTCAAGCAGGAGAAAAGGGAAAACTTGGAGTT
  CCAGGATTACCAGGATATCCAGGAAGACAAGGTCCAAAGGGTTCCACTGGATTCCCTGGG
  TTTCCAGGTGCCAATGGAGAGAAAGGTGCACGGGGAGTAGCTGGCAAACCAGGCCCTCGG
  GGTCAGCGTGGTCCAACGGGTCCTCGAGGTTCAAGAGGTGCAAGAGGTCCCACTGGGAAA
  CCTGGGCCAAAGGGCACTTCAGGTGGCGATGGCCCTCCTGGCCCTCCAGGTGAAAGAGGT
  CCTCAAGGACCTCAGGGTCCAGTTGGATTCCCTGGACCAAAAGGCCCTCCTGGACCACCT
  GGGAAGGATGGGCTGCCAGGACACCCTGGGCAACGTGGGGAGACTGGATTTCAAGGCAAG
  ACCGGCCCTCCTGGGCCAGGGGGAGTGGTTGGACCACAGGGACCAACCGGTGAGACTGGT
  CCAATAGGGGAACGTGGGCATCCTGGCCCTCCTGGCCCTCCTGGTGAGCAAGGTCTTCCT
  GGTGCTGCAGGAAAAGAAGGTGCAAAGGGTGATCCAGGTCCTCAAGGTATCTCAGGGAAA
  GATGGACCAGCAGGATTACGTGGTTTCCCAGGGGAAAGAGGTCTTCCTGGAGCTCAGGGT
  GCACCTGGACTGAAAGGAGGGGAAGGTCCCCAGGGCCCACCAGGTCCAGTTGGCTCACCA
  GGAGAACGTGGGTCAGCAGGTACAGCTGGCCCAATTGGTTTACCAGGGCGCCCGGGACCT
  CAGGGTCCTCCTGGTCCAGCTGGAGAGAAAGGTGCTCCTGGAGAAAAAGGTCCCCAAGGG
  CCTGCAGGGAGAGATGGAGTTCAAGGTCCTGTTGGTCTCCCAGGGCCAGCTGGTCCTGCC
  GGCTCCCCTGGGGAAGACGGAGACAAGGGTGAAATTGGTGAGCCGGGACAAAAAGGCAGC
  AAGGGTGACAAGGGAGAAAATGGCCCTCCCGGTCCCCCAGGTCTTCAAGGACCAGTTGGT
  GCCCCTGGAATTGCTGGAGGTGATGGTGAACCAGGTCCTAGAGGACAGCAGGGGATGTTT
  GGGCAAAAAGGTGATGAGGGTGCCAGAGGCTTCCCTGGACCTCCTGGTCCAATAGGTCTT
  CAGGGTCTGCCAGGCCCACCTGGTGAAAAAGGTGAAAATGGGGATGTTGGTCCCATGGGG
  CCACCTGGTCCTCCAGGCCCAAGAGGCCCTCAAGGTCCCAATGGAGCTGATGGACCACAA
  GGACCCCCAGGGTCTGTTGGTTCAGTTGGTGGTGTTGGAGAAAAGGGTGAACCTGGAGAA
  GCAGGGAACCCAGGGCCTCCTGGGGAAGCAGGTGTAGGCGGTCCCAAAGGAGAAAGAGGA
  GAGAAAGGGGAAGCTGGTCCACCTGGAGCTGCTGGACCTCCAGGTGCCAAGGGGCCACCA
  GGTGATGATGGCCCTAAGGGTAACCCGGGTCCTGTTGGTTTTCCTGGAGATCCTGGTCCT
  CCTGGGGAACCTGGCCCTGCAGGTCAAGATGGTGTTGGTGGTGACAAGGGTGAAGATGGA
  GATCCTGGTCAACCGGGTCCTCCTGGCCCATCTGGTGAGGCTGGCCCACCAGGTCCTCCT
  GGAAAACGAGGTCCTCCTGGAGCTGCAGGTGCAGAGGGAAGACAAGGTGAAAAAGGTGCT
  AAGGGGGAAGCAGGTGCAGAAGGTCCTCCTGGAAAAACCGGCCCAGTCGGTCCTCAGGGA
  CCTGCAGGAAAGCCTGGTCCAGAAGGTCTTCGGGGCATCCCTGGTCCTGTGGGAGAACAA
  GGTCTCCCTGGAGCTGCAGGCCAAGATGGACCACCTGGTCCTATGGGACCTCCTGGCTTA
  CCTGGTCTCAAAGGTGACCCTGGCTCCAAGGGTGAAAAGGGACATCCTGGTTTAATTGGC
  CTGATTGGTCCTCCAGGAGAACAAGGGGAAAAAGGTGACCGAGGGCTCCCTGGAACTCAA
  GGATCTCCAGGAGCAAAAGGGGATGGGGGAATTCCTGGTCCTGCTGGTCCCTTAGGTCCA
  CCTGGTCCTCCAGGTTTACCAGGTCCTCAAGGCCCAAAGGGTAACAAAGGCTCTACTGGA
  CCCGCTGGCCAGAAAGGTGACAGTGGTCTTCCAGGGCCTCCTGGGTCTCCAGGTCCACCT
  GGTGAAGTCATTCAGCCTTTACCAATCTTGTCCTCCAAAAAAACGAGAAGACATACTGAA
  GGCATGCAAGCAGATGCAGATGATAATATTCTTGATTACTCGGATGGAATGGAAGAAATA
  TTTGGTTCCCTCAATTCCCTGAAACAAGACATTGAGCATATGAAATTTCCAATGGGTACT
  CAGACCAATCCAGCCCGAACTTGTAAAGACCTGCAACTCAGCCATCCTGACTTCCCAGAT
  GGTGAATATTGGATTGATCCTAACCAAGGTTGCTCAGGAGATTCCTTCAAAGTTTACTGT
  AATTTCACATCTGGTGGTGAGACTTGCATTTATCCAGACAAAAAATCTGAGGGAGTAAGA
  ATTTCATCATGGCCAAAGGAGAAACCAGGAAGTTGGTTTAGTGAATTTAAGAGGGGAAAA
  CTGCTTTCATACTTAGATGTTGAAGGAAATTCCATCAATATGGTGCAAATGACATTCCTG
  AAACTTCTGACTGCCTCTGCTCGGCAAAATTTCACCTACCACTGTCATCAGTCAGCAGCC
  TGGTATGATGTGTCATCAGGAAGTTATGACAAAGCACTTCGCTTCCTGGGATCAAATGAT
  GAGGAGATGTCCTATGACAATAATCCTTTTATCAAAACACTGTATGATGGTTGTGCGTCC
  AGAAAAGGCTATGAAAAGACTGTCATTGAAATCAATACACCAAAAATTGATCAAGTACCT
  ATTGTTGATGTCATGATCAATGACTTTGGTGATCAGAATCAGAAGTTCGGATTTGAAGTT
  GGTCCTGTTTGTTTTCTTGGCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_080630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_080630.1, NP_542197.1
• RefSeq Size: 6202 bp
• RefSeq ORF: 5304 bp
• Locus ID: 1301
• Cytogenetics: 1p21.1
• Protein Pathways: ECM-receptor interaction, Focal adhesion
• Gene Summary: 'This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]'
  Transcript Variant: This variant (C, previously referred to as D) includes alternate exon 6A but lacks two other alternate exons, resulting in the loss of an in-frame segment in the coding region, compared to variant A. The encoded isoform (C, previously referred to as D) is shorter than isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.