ANKRD15 (KANK1) (NM_015158) Human Untagged Clone

CAT#: SC309139

KANK1 (untagged)-Human KN motif and ankyrin repeat domains 1 (KANK1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KANK1
• Synonyms: ANKRD15; CPSQ2; KANK
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015158, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCACACCACAAAGGTTAACGGCAGTGCCTCAGGAAAAGCAGGTGATATTCTCAGTGGAGACCAGG
  ACAAGGAACAGAAAGACCCTTACTTTGTGGAGACCCCCTATGGTTATCAACTAGACTTAGATTTCCTCAA
  ATATGTGGATGACATACAGAAGGGAAATACCATCAAAAGACTGAACATCCAGAAGAGGCGGAAGCCGTCC
  GTGCCATGCCCAGAACCCAGGACCACATCTGGTCAGCAAGGTATATGGACTTCCACTGAATCCCTCTCAT
  CCTCCAACAGTGATGACAACAAGCAGTGCCCCAACTTCCTCATAGCCAGAAGTCAAGTTACATCAACTCC
  AATCTCAAAGCCACCTCCCCCTCTGGAGACCTCACTCCCTTTTCTTACCATCCCAGAAAATCGACAGCTG
  CCACCTCCCTCACCACAACTCCCAAAGCATAACCTTCATGTCACCAAGACACTGATGGAGACCCGGAGAA
  GACTGGAACAGGAGAGAGCCACCATGCAGATGACACCGGGTGAGTTCAGAAGGCCCAGGCTGGCCAGTTT
  TGGAGGCATGGGCACCACAAGCTCCCTCCCTTCTTTTGTGGGTTCTGGAAACCACAATCCTGCCAAGCAC
  CAGCTTCAGAATGGATACCAAGGTAATGGGGATTATGGTAGCTATGCCCCAGCTGCTCCCACCACTTCCT
  CCATGGGGAGCTCCATCCGCCACAGCCCCCTGAGCTCAGGGATCTCCACCCCAGTGACCAACGTGAGCCC
  CATGCACCTGCAGCACATCCGCGAGCAGATGGCCATTGCTCTGAAACGCCTGAAGGAGCTGGAGGAGCAG
  GTGCGAACCATCCCTGTGCTCCAGGTAAAGATCTCTGTCTTGCAAGAAGAGAAAAGGCAGTTGGTCTCAC
  AGCTGAAAAACCAAAGGGCTGCATCCCAGATCAATGTCTGTGGTGTGAGGAAGCGGTCCTATAGTGCGGG
  GAACGCCTCCCAGCTGGAACAGCTCTCCCGGGCCCGAAGAAGTGGCGGGGAATTATACATTGACTATGAG
  GAGGAAGAAATGGAGACCGTAGAACAGAGCACGCAGAGGATAAAGGAGTTCCGGCAACTTACAGCAGACA
  TGCAAGCCCTGGAGCAGAAGATCCAGGACAGCAGCTGTGAGGCCTCCTCAGAGCTCAGGGAGAATGGAGA
  GTGCCGGTCTGTGGCTGTGGGTGCCGAGGAGAACATGAACGACATCGTCGTGTACCACAGAGGCTCCAGG
  TCCTGTAAGGATGCAGCTGTAGGGACACTTGTTGAGATGAGAAATTGTGGGGTCAGCGTGACAGAGGCCA
  TGCTTGGAGTGATGACTGAAGCTGACAAAGAAATTGAGCTGCAACAGCAGACCATAGAATCCTTGAAGGA
  AAAGATCTATCGCCTAGAAGTACAGCTTAGAGAAACCACCCATGACCGGGAGATGACTAAACTGAAACAA
  GAGCTGCAGGCTGCTGGATCGAGGAAAAAGGTTGACAAAGCCACGATGGCCCAGCCGCTTGTTTTCAGTA
  AGGTGGTGGAGGCAGTGGTGCAGACCAGAGACCAAATGGTCGGCAGTCACATGGACCTGGTGGACACGTG
  TGTTGGGACCTCCGTGGAAACAAACAGTGTAGGCATCTCCTGCCAGCCTGAATGTAAGAATAAAGTCGTA
  GGGCCTGAGCTGCCTATGAATTGGTGGATTGTTAAGGAGAGGGTGGAAATGCATGACCGATGTGCTGGGA
  GGTCTGTGGAAATGTGTGACAAGAGTGTGAGTGTGGAAGTCAGCGTCTGCGAAACAGGCAGCAACACAGA
  GGAGTCTGTGAACGACCTCACACTCCTCAAGACAAACTTGAATCTCAAAGAAGTGCGGTCTATCGGTTGT
  GGAGATTGTTCTGTTGACGTGACCGTCTGCTCTCCAAAGGAGTGCGCCTCCCGGGGCGTGAACACTGAGG
  CTGTTAGCCAGGTGGAAGCTGCCGTCATGGCAGTGCCTCGTACTGCAGACCAGGACACTAGCACAGATTT
  GGAACAGGTGCACCAGTTCACCAACACCGAGACGGCCACCCTCATAGAGTCCTGCACCAACACTTGTCTA
  AGCACTTTGGACAAGCAGACCAGCACCCAGACTGTGGAGACGCGGACAGTAGCTGTAGGAGAAGGCCGTG
  TCAAGGACATCAACTCCTCCACCAAGACGCGGTCCATTGGTGTTGGAACGTTGCTTTCTGGCCATTCTGG
  GTTTGACAGGCCATCAGCTGTGAAGACCAAAGAGTCAGGTGTGGGGCAGATAAATATTAACGACAACTAT
  CTGGTTGGTCTCAAAATGAGGACTATAGCTTGTGGGCCACCACAGTTGACTGTGGGGCTGACAGCCAGCA
  GAAGGAGCGTGGGGGTTGGGGATGACCCTGTAGGGGAATCTCTGGAGAACCCCCAGCCTCAAGCTCCACT
  TGGAATGATGACTGGCCTGGATCACTACATTGAGCGTATCCAGAAGCTGCTGGCAGAACAGCAGACACTG
  CTGGCTGAGAACTACAGTGAACTGGCAGAAGCTTTCGGGGAACCTCACTCACAGATGGGCTCCCTCAACT
  CTCAGCTCATCAGCACCCTGTCGTCTATCAACTCTGTCATGAAATCTGCAAGCACTGAAGAGCTGAGGAA
  CCCTGACTTCCAGAAAACCAGTCTGGGTAAAATCACAGGCAATTATTTGGGATATACCTGTAAGTGTGGG
  GGCCTTCAGTCAGGAAGTCCCTTAAGCTCCCAGACATCCCAGCCTGAGCAAGAAGTGGGGACCTCAGAAG
  GAAAGCCAATCAGCAGCCTGGATGCCTTCCCCACTCAGGAAGGTACGCTGTCTCCAGTGAACCTGACAGA
  CGACCAGATCGCCGCTGGCCTCTATGCATGTACAAACAATGAAAGTACACTGAAGTCCATCATGAAGAAG
  AAAGATGGTAACAAAGATTCAAATGGCGCAAAAAAGAATCTTCAGTTTGTTGGCATTAATGGAGGGTATG
  AAACAACTTCAAGTGATGATTCCAGCTCAGATGAAAGCTCTTCTTCCGAGTCAGATGACGAGTGTGATGT
  CATTGAGTATCCTCTTGAAGAAGAGGAGGAGGAGGAGGATGAAGACACTCGGGGAATGGCAGAAGGGCAC
  CATGCAGTTAATATTGAAGGTTTGAAGTCTGCCAGGGTGGAAGATGAAATGCAGGTTCAAGAATGTGAAC
  CTGAGAAGGTGGAAATCAGAGAGAGGTATGAATTAAGTGAAAAGATGTTGTCTGCATGCAACTTACTGAA
  AAATACTATAAATGACCCCAAAGCTTTGACCAGCAAAGATATGAGGTTCTGTCTGAACACCCTCCAGCAC
  GAGTGGTTCCGCGTGTCCAGTCAGAAGTCAGCCATTCCAGCCATGGTGGGGGACTACATAGCTGCTTTTG
  AGGCCATTTCCCCAGATGTCCTCCGCTATGTCATCAACTTGGCAGACGGCAACGGCAACACAGCCCTCCA
  TTACAGCGTGTCCCACTCCAACTTCGAGATTGTGAAGCTGCTGTTAGATGCCGATGTGTGTAATGTGGAT
  CACCAGAACAAGGCAGGCTACACCCCCATCATGTTGGCGGCCCTCGCCGCTGTGGAAGCAGAGAAGGACA
  TGCGGATTGTGGAAGAACTCTTCGGCTGTGGGGATGTGAATGCCAAAGCTAGTCAGGCGGGACAGACGGC
  CCTCATGCTGGCGGTCAGTCACGGACGGATAGACATGGTGAAGGGCCTTCTGGCCTGTGGGGCTGATGTC
  AACATCCAGGATGACGAGGGCTCCACGGCCCTCATGTGTGCCAGCGAGCACGGGCACGTGGAGATTGTCA
  AGCTGCTGCTGGCCCAGCCCGGCTGCAACGGTCACCTAGAGGACAACGATGGCAGCACTGCGCTCTCAAT
  CGCCCTGGAAGCAGGACACAAGGACATCGCTGTTCTTCTGTATGCCCATGTCAACTTTGCAAAAGCCCAG
  TCTCCGGGCACCCCTAGGCTTGGAAGGAAGACGTCTCCTGGCCCCACCCACCGAGGTTCATTTGATTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015158
• ORF Size: 4059 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015158.3, NP_055973.2
• RefSeq Size: 5090
• RefSeq ORF: 4059
• Locus ID: 23189
• Gene Summary: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (1) represents the shortest transcript but encodes the longer isoform (a, also known as Kank-L). Variants 1, 3 and 4 all encode isoform a.