NFAT5 (NM_173214) Human Untagged Clone

CAT#: SC309213

NFAT5 (untagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFAT5
• Synonyms: NF-AT5; NFATL1; NFATZ; OREBP; TONEBP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_173214, the custom clone sequence may differ by one or more nucleotides
  ATGGGCGGTGCTTGCAGCTCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCA
  GTCACCGACAGCAAGGCTATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAAC
  AGAGGGGTAAGTGAAAAGCAGTTAACCAGTAACACAGTTCAGCAGCATCCATCAACACCG
  AAGAGGCACACAGTCTTGTACATCTCACCACCACCTGAGGACTTGCTGGATAACAGTCGG
  ATGTCCTGCCAGGATGAGGGGTGTGGATTGGAATCTGAGCAGAGCTGCAGTATGTGGATG
  GAGGATTCCCCCTCCAACTTCAGTAACATGAGCACCAGTTCCTACAATGATAACACTGAG
  GTACCTCGTAAATCACGAAAACGAAATCCAAAGCAGAGGCCGGGGGTCAAACGACGAGAT
  TGTGAAGAATCTAATATGGATATATTTGATGCCGACAGTGCCAAAGCACCTCACTATGTG
  CTTTCTCAGCTTACCACGGACAACAAAGGCAACTCAAAAGCGGGAAATGGAACATTGGAA
  AACCAAAAAGGAACTGGAGTAAAGAAGAGCCCTATGTTGTGTGGACAATATCCTGTTAAA
  AGTGAGGGAAAGGAGCTGAAGATAGTTGTACAACCTGAGACACAGCACCGAGCTCGGTAC
  CTGACTGAGGGCAGCCGTGGCTCAGTGAAAGATAGAACACAGCAAGGCTTTCCTACAGTA
  AAGCTGGAAGGCCATAATGAACCTGTAGTGTTGCAAGTGTTTGTGGGCAACGACTCTGGA
  CGAGTGAAACCACATGGATTTTATCAGGCCTGCAGAGTAACTGGACGAAATACAACTCCT
  TGCAAAGAAGTGGACATTGAAGGCACTACTGTTATAGAAGTCGGCCTTGATCCTAGCAAC
  AACATGACACTGGCGGTGGACTGCGTAGGGATATTGAAATTGAGGAATGCTGATGTCGAA
  GCCAGAATAGGAATTGCTGGTTCCAAGAAGAAAAGCACTCGTGCCAGATTGGTTTTTCGA
  GTTAATATCATGAGGAAAGATGGCTCCACTTTGACACTGCAAACACCCTCTTCTCCAATT
  TTGTGTACTCAGCCAGCAGGAGTGCCAGAAATCTTAAAGAAAAGCTTGCATAGCTGTTCA
  GTGAAAGGAGAAGAAGAAGTGTTTTTAATCGGCAAGAACTTTCTGAAAGGAACTAAAGTT
  ATTTTCCAAGAAAATGTTTCTGATGAAAACTCTTGGAAGTCAGAAGCTGAAATTGATATG
  GAACTATTTCATCAGAATCATCTTATTGTGAAGGTTCCTCCCTATCATGACCAACATATA
  ACTTTGCCTGTGTCAGTGGGAATATATGTAGTGACAAATGCTGGAAGATCTCATGATGTT
  CAACCATTCACTTACACTCCAGACCCAGCAGCAGCTGGTGCTTTGAATGTAAATGTGAAG
  AAGGAAATATCTAGTCCAGCAAGACCTTGCTCTTTTGAAGAGGCCATGAAAGCAATGAAA
  ACTACTGGATGTAATTTAGATAAGGTAAATATTATCCCTAATGCCCTGATGACTCCACTC
  ATACCAAGCAGTATGATTAAGAGTGAAGATGTTACTCCAATGGAAGTAACAGCAGAAAAA
  AGATCTTCCACTATTTTTAAGACTACAAAGTCTGTTGGATCAACTCAGCAAACATTAGAA
  AACATCTCAAACATAGCAGGAAATGGCTCTTTTTCATCACCATCATCTTCCCACCTACCT
  TCTGAAAATGAAAAACAGCAGCAGATTCAGCCCAAGGCATACAACCCAGAGACCCTGACA
  ACTATTCAAACCCAGGACATCTCACAGCCTGGTACTTTTCCAGCAGTTTCTGCTTCTAGT
  CAGCTGCCCAACAGCGATGCACTATTGCAGCAGGCTACACAGTTTCAGACAAGAGAAACT
  CAGTCTAGAGAGATATTACAGTCAGATGGTACAGTGGTTAATTTGTCACAACTGACTGAG
  GCATCACAACAACAGCAGCAGTCACCACTACAAGAACAAGCACAGACTTTACAGCAGCAG
  ATTTCATCAAATATTTTTCCATCACCAAATAGTGTGAGTCAGCTTCAGAATACTATTCAG
  CAGCTGCAAGCAGGGAGTTTCACAGGCAGTACTGCTAGTGGCAGCAGTGGAAGTGTTGAC
  TTGGTCCAACAAGTTTTAGAGGCACAGCAGCAGTTATCTTCAGTTTTATTTTCTGCTCCA
  GATGGTAATGAGAATGTTCAAGAGCAGCTTAGTGCAGATATTTTTCAACAAGTCAGTCAA
  ATTCAGAGTGGTGTAAGCCCTGGAATGTTTTCCTCAACAGAGCCAACAGTCCATACCAGA
  CCAGATAATTTATTACCTGGAAGAGCTGAAAGTGTTCATCCACAGTCTGAAAACACGTTA
  TCTAATCAACAGCAGCAGCAGCAGCAGCAACAGCAAGTGATGGAATCTTCAGCCGCAATG
  GTGATGGAGATGCAACAGAGTATCTGCCAGGCAGCTGCCCAGATTCAGTCAGAGTTATTC
  CCTTCAACTGCTTCAGCAAATGGAAACCTTCAGCAATCGCCAGTTTACCAGCAGACTTCT
  CACATGATGAGTGCATTGTCTACCAATGAGGATATGCAAATGCAGTGTGAATTGTTTTCT
  TCTCCTCCTGCAGTTTCTGGAAATGAAACTTCTACAACTACCACACAGCAGGTTGCAACC
  CCTGGCACTACCATGTTTCAGACATCAAGTTCAGGAGATGGAGAAGAAACTGGAACACAA
  GCAAAACAGATTCAGAACAGTGTCTTTCAGACCATGGTCCAAATGCAACATAGTGGGGAC
  AATCAACCTCAAGTTAACCTTTTTTCATCCACAAAAAGTATGATGAGTGTTCAGAATAGT
  GGTACCCAACAACAAGGTAATGGTTTATTCCAGCAAGGGAATGAGATGATGTCACTTCAA
  TCTGGAAATTTTTTGCAGCAGTCTTCTCATTCACAGGCCCAACTTTTTCATCCTCAAAAT
  CCTATTGCCGATGCTCAGAACCTTTCCCAGGAAACTCAAGGTTCTCTCTTTCATAGTCCA
  AATCCTATTGTCCACAGTCAGACTTCTACAACCTCCTCTGAACAAATGCAGCCTCCAATG
  TTTCACTCTCAAAGTACCATTGCTGTGTTACAGGGCTCTTCAGTTCCTCAAGACCAGCAG
  TCAACCAACATATTTCTTTCCCAGAGTCCCATGAATAATCTTCAGACTAACACAGTAGCC
  CAAGAAGCATTTTTTGCAGCACCGAACTCAATTTCTCCACTTCAGTCAACATCAAACAGT
  GAACAACAAGCTGCTTTCCAACAGCAAGCTCCAATATCACACATCCAGACTCCTATGCTT
  TCCCAAGAACAGGCACAACCCCCGCAGCAGGGTTTATTTCAGCCTCAGGTGGCCCTGGGC
  TCCCTTCCACCTAATCCAATGCCTCAAAGCCAACAAGGAACCATGTTCCAGTCACAGCAC
  TCAATAGTTGCCATGCAGAGTAACTCTCCATCCCAGGAACAGCAGCAGCAGCAGCAACAG
  CAGCAGCAACAGCAGCAGCAACAACAACAGAGCATTTTATTCAGTAATCAGAATACCATG
  GCTACAATGGCGTCTCCAAAGCAACCACCACCAAACATGATATTCAACCCAAATCAAAAT
  CCAATGGCTAATCAGGAGCAACAGAACCAGTCAATTTTTCACCAACAAAGTAACATGGCC
  CCAATGAATCAAGAGCAACAGCCCATGCAATTTCAGAGTCAGTCCACAGTTTCCTCACTT
  CAGAACCCAGGTCCTACCCAGTCGGAATCATCACAGACCCCCTTGTTCCATAGCTCTCCT
  CAGATTCAGTTGGTACAAGGGTCACCTAGTTCTCAAGAGCAGCAAGTAACTCTCTTCTTA
  TCTCCAGCATCCATGTCTGCCTTGCAGACCAGTATAAATCAACAAGATATGCAACAGTCT
  CCTCTTTATTCCCCTCAGAACAACATGCCTGGAATTCAAGGAGCCACATCTTCGCCTCAA
  CCACAGGCTACTTTATTTCACAACACAGCAGGAGGCACAATGAACCAACTGCAGAATTCT
  CCTGGCTCATCTCAGCAGACATCAGGAATGTTCTTATTTGGCATTCAAAATAACTGTAGT
  CAGCTTTTAACCTCTGGACCAGCTACATTGCCTGATCAGTTGATGGCCATAAGTCAGCCA
  GGCCAACCACAAAACGAGGGCCAGCCACCTGTGACAACACTTCTTTCTCAGCAAATGCCA
  GAGAATTCTCCACTGGCATCCTCTATAAACACCAACCAGAACATCGAAAAGATTGATTTG
  CTTGTTTCATTGCAAAACCAAGGGAACAACTTGACTGGCTCCTTTTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_173214
• ORF Size: 4368 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_173214.1, NP_775321.1
• RefSeq Size: 14185
• RefSeq ORF: 4368
• Locus ID: 10725
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) lacks an exon in the 5' UTR, compared to variant 1. Variants 1, 4 and 5 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.