NLRP10 (NM_176821) Human Untagged Clone

CAT#: SC309242

NLRP10 (untagged)-Human NLR family, pyrin domain containing 10 (NLRP10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP10
• Synonyms: CLR11.1; NALP10; NOD8; PAN5; PYNOD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_176821, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCATGGCCAAGGCCAGAAAGCCCCGGGAGGCATTGCTCTGGGCCTTGAGTGACCTTGAGGAGAACG
  ATTTCAAGAAGTTAAAGTTCTACTTACGGGATATGACCCTGTCTGAGGGCCAGCCCCCACTGGCCAGAGG
  GGAGTTGGAGGGCCTGATTCCGGTGGACCTGGCAGAATTACTGATTTCAAAGTATGGAGAAAAGGAGGCT
  GTGAAAGTTGTCCTCAAGGGCTTGAAGGTCATGAACCTGTTGGAACTTGTGGACCAGCTCAGCCATATTT
  GTCTGCATGATTACAGAGAAGTATACCGAGAGCATGTGCGCTGCCTAGAGGAATGGCAGGAAGCAGGAGT
  CAATGGCAGATACAACCAGGTGCTCCTGGTGGCCAAGCCCAGCTCAGAGAGCCCAGAATCACTTGCCTGC
  CCCTTCCCGGAGCAGGAGCTGGAGTCTGTCACGGTGGAGGCTCTATTTGATTCAGGGGAAAAGCCCTCAC
  TGGCCCCATCCTTAGTTGTGCTACAGGGGTCGGCTGGCACTGGAAAGACAACTCTCGCCAGAAAAATGGT
  GTTGGACTGGGCCACCGGTACTCTGTACCCAGGCCGGTTTGATTATGTCTTTTATGTAAGCTGCAAAGAA
  GTGGTCCTGCTGCTGGAGAGCAAACTGGAGCAGCTCCTTTTCTGGTGCTGCGGGGACAATCAAGCCCCTG
  TCACAGAGATTCTGAGGCAGCCAGAGCGGCTCCTGTTCATCCTGGATGGCTTTGATGAGCTGCAGAGGCC
  CTTTGAAGAAAAGTTGAAGAAGAGGGGTTTGAGTCCCAAGGAGAGCCTGCTGCACCTTCTAATTAGGAGA
  CATACACTCCCCACGTGCTCCCTTCTCATCACCACCCGGCCCCTGGCTTTGAGGAATCTGGAGCCCTTGC
  TGAAACAAGCACGTCATGTCCATATCCTAGGCTTCTCTGAGGAGGAGAGGGCGAGGTACTTCAGCTCCTA
  TTTCACGGATGAGAAGCAAGCTGACCGTGCCTTCGACATTGTACAGAAAAATGACATTCTCTACAAAGCG
  TGTCAGGTTCCAGGCATTTGCTGGGTGGTCTGCTCCTGGCTGCAGGGGCAGATGGAGAGAGGCAAAGTTG
  TCTTAGAGACACCTAGAAACAGCACTGACATCTTCATGGCTTACGTCTCCACCTTTCTGCCGCCCGATGA
  TGATGGGGGCTGCTCCGAGCTTTCCCGGCACAGGGTCCTGAGGAGTCTGTGCTCCCTAGCAGCTGAAGGG
  ATTCAGCACCAGAGGTTCCTATTTGAAGAAGCTGAGCTCAGGAAACATAATTTAGATGGCCCCAGGCTTG
  CCGCTTTCCTGAGTAGTAACGACTACCAATTGGGACTTGCCATCAAGAAGTTCTACAGCTTCCGCCACAT
  CAGCTTCCAGGACTTTTTTCATGCCATGTCTTACCTGGTGAAAGAGGACCAAAGCCGGCTGGGGAAGGAG
  TCCCGCAGAGAAGTGCAAAGGCTGCTGGAGGTAAAGGAGCAGGAAGGGAATGATGAGATGACCCTCACTA
  TGCAGTTTTTACTGGACATCTCGAAAAAAGACAGCTTCTCGAACTTGGAGCTCAAGTTCTGCTTCAGAAT
  TTCTCCCTGTTTAGCGCAGGATCTGAAGCATTTTAAAGAACAGATGGAATCTATGAAGCACAACAGGACC
  TGGGATTTGGAATTCTCCCTGTATGAAGCTAAAATAAAGAATCTGGTAAAAGGTATTCAGATGAACAATG
  TATCATTCAAGATAAAACATTCAAATGAAAAGAAATCACAGAGCCAGAATTTATTTTCTGTCAAAAGCAG
  CTTGAGTCATGGACCTAAGGAGGAGCAAAAATGTCCTTCTGTCCATGGACAGAAGGAGGGCAAAGATAAT
  ATAGCAGGAACACAAAAGGAAGCTTCTACTGGAAAAGGCAGAGGGACAGAGGAAACACCAAAAAATACTT
  ACATATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_176821
• ORF Size: 1968 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_176821.3, NP_789791.1
• RefSeq Size: 2020
• RefSeq ORF: 1968
• Locus ID: 338322
• Gene Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]