KCNMB2 (NM_181361) Human Untagged Clone

CAT#: SC309268

KCNMB2 (untagged)-Human potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNMB2
• Synonyms: MGC22431
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005832.3 AGTATGAAGCAGCTTTAACGGAGCTCCAGATAACTAATTTCAAGCATGGCTGTCTAGCGT
  GCCTGTCACTCCTATTGTCCTTCCAAACTCTTTCAGACATTTTGAGCAGGGAGTATTAAA
  GCTATGAGTTAGAAAGGGTTGTGACATTAATGGTCCACAAAGGCTTTAGGCACAAGAGGT
  AATGATGATTACCGGTGGCTATTTGGAGGACTGCACCGGATCGCTGTCATTAAAAATTAA
  GCGTGGCTTTTGAGGAAGATGTGACAACTACCGGAGGTCTTTTTGCCATTCCTCCAGGAC
  ATCCACCATAAGGAAAGGAGACCCTGGACCAACATTCTCTAAGATGTTTATATGGACCAG
  TGGCCGGACCTCTTCATCTTATAGACATGATGAAAAAAGAAATATTTACCAGAAAATCAG
  GGACCATGACCTCCTGGACAAAAGGAAAACAGTCACAGCACTGAAGGCAGGAGAGGACCG
  AGCTATTCTCCTGGGACTGGCTATGATGGTGTGCTCCATCATGATGTATTTTCTGCTGGG
  AATCACACTCCTGCGCTCATACATGCAGAGCGTGTGGACCGAAGAGTCTCAATGCACCTT
  GCTGAATGCGTCCATCACGGAAACATTTAACTGCTCCTTCAGCTGTGGTCCAGACTGCTG
  GAAACTTTCTCAGTACCCCTGCCTCCAGGTGTACGTTAACCTGACTTCTTCCGGGGAAAA
  GCTCCTCCTCTACCACACAGAAGAGACAATAAAAATCAATCAGAAGTGCTCCTATATACC
  TAAATGTGGAAAAAATTTTGAAGAATCCATGTCCCTGGTGAATGTTGTCATGGAAAACTT
  CAGGAAGTATCAACACTTCTCCTGCTATTCTGACCCAGAAGGAAACCAGAAGAGTGTTAT
  CCTAACCAAACTCTACAGTTCCAACGTGCTGTTCCATTCACTCTTCTGGCCAACCTGTAT
  GATGGCTGGGGGTGTGGCAATTGTTGCCATGGTGAAACTTACACAGTACCTCTCCCTACT
  ATGTGAGAGGATCCAACGGATCAATAGATAAATGCAAAAATGGATAAAATAATTTTTGTT
  AAAGCTCAAATACTGTTTTCTTTCATTCTTCACCAAAGAACCTTAAGTTTGTAACGTGCA
  GTCTGTTATGAGTTCCCTAATATATTCTTATATGTAGAGCAATAATGCAAAAGCTGTTCT
  ATATGCAAACATGATGTCTTTATTATTCAGGAGAATAAATAACTGTTTTGTGTCGAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005832.3 unedited
  TCGTATGCGTCCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCCATTACGGCC
  GGGGAGTATGAAGCAGCTTTAACGGAGCTCCAGATAACTAATTTCAAGCATGGCTGTCTA
  GCGTGCCTGTCACTCCTATTGTCCTTCCAAACTCTTTCAGACATTTTGAGCAGGGAGTAT
  TAAAGCTATGAGTTAGAAAGGGTTGTGACATTAATGGTCCACAAAGGCTTTAGGCACAAG
  AGGTAATGATGATTACCGGTGGCTATTTGGAGGACTGCACCGGATCGCTGTCATTAAAAA
  TTAAGCGTGGCTTTTGAGGAAGATGTGACAACTACCGGAGGTCTTTTTGCCATTCCTCCA
  GGACATCCACCATAAGGAAAGGAGACCCTGGACCAACATTCTCTAAGATGTTTATATGGA
  CCAGTGGCCGGACCTCTTCATCTTATAGACATGATGAAAAAAGAAATATTTACCAGAAAA
  TCAGGGACCATGACCTCCTGGACAAAAGGAAAACAGTCACAGCACTGAAGGCAGGAGAGG
  ACCGAGCTATTCTCCTGGGACTGGCTATGATGGTGTGCTCCATCATGATGTATTTTCTGC
  TGGGAATCACACTCCTGCGCTCATACATGCAGAGCGTGTGGACCGAAGAGTCTCAATGCA
  CCTTGCTGAATGCGTCCATCACGGAAACATTTAACTGCTCCTTCAGCTGTGGTCCAGACT
  GCTGGAAACTTTCTCAGTACCCCTGCCTCCAGGTGTACGTTAACCTGACTTCTTCCGGGA
  AAAGCTCCTCCTCTACCACACAGAGAGACATAAAATCAATCAGAGTGCCTCCTATATACC
  TAAATGTGAAAATTTGAGATCCATGTCCTGTGATGTTGTCATGAAAACTCAGAGTATCAC
  ACTCTCTGCTATTCTGACCGAGAACAGAGATGTATCTACAACTTTACGTCACGGCTGTCA
  TCCTCTCTGCACTGTATGATGCTAGATTGCAAG
• Restriction Sites: Please inquire
• ACCN: NM_181361
• ORF Size: 708 bp
• Insert Size: 1300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_181361.1, NP_852006.1
• RefSeq Size: 2543
• RefSeq ORF: 708
• Locus ID: 10242
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Vascular smooth muscle contraction
• Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.