COL11A1 (NM_080629) Human Untagged Clone
CAT#: SC309482
COL11A1 (untagged)-Human collagen, type XI, alpha 1 (COL11A1), transcript variant B
"NM_080629" in other vectors (2)
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Other products for "COL11A1"
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | COL11A1 |
Synonyms | CO11A1; COLL6; STL2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>NCBI ORF sequence for NM_080629, the custom clone sequence may differ by one or more nucleotides
ATGGAGCCGTGGTCCTCTAGGTGGAAAACGAAACGGTGGCTCTGGGATTTCACCGTAACAACCCTCGCAT TGACCTTCCTCTTCCAAGCTAGAGAGGTCAGAGGAGCTGCTCCAGTTGATGTACTAAAAGCACTAGATTT TCACAATTCTCCAGAGGGAATATCAAAAACAACGGGATTTTGCACAAACAGAAAGAATTCTAAAGGCTCA GATACTGCTTACAGAGTTTCAAAGCAAGCACAACTCAGTGCCCCAACAAAACAGTTATTTCCAGGTGGAA CTTTCCCAGAAGACTTTTCAATACTATTTACAGTAAAACCAAAAAAAGGAATTCAGTCTTTCCTTTTATC TATATATAATGAGCATGGTATTCAGCAAATTGGTGTTGAGGTTGGGAGATCACCTGTTTTTCTGTTTGAA GACCACACTGGAAAACCTGCCCCAGAAGACTATCCCCTCTTCAGAACTGTTAACATCGCTGACGGGAAGT GGCATCGGGTAGCAATCAGCGTGGAGAAGAAAACTGTGACAATGATTGTTGATTGTAAGAAGAAAACCAC GAAACCACTTGATAGAAGTGAGAGAGCAATTGTTGATACCAATGGAATCACGGTTTTTGGAACAAGGATT TTGGATGAAGAAGTTTTTGAGGGGGACATTCAGCAGTTTTTGATCACAGGTGATCCCAAGGCAGCATATG ACTACTGTGAGCATTATAGTCCAGACTGTGACTCTTCAGCACCCAAGGCTGCTCAAGCTCAGGAACCTCA GATAGATGAGAAAAAGAAATCCAATTTCAAAAAGAAGATGAGGACAGTGGCTACTAAATCAAAGGAAAAA TCCAAAAAGTTTACACCCCCCAAATCTGAAAAATTTTCATCCAAGAAGAAGAAAAGTTATCAAGCATCAG CAAAAGCCAAACTAGGGGTAAAGGCAAACATCGTTGATGATTTTCAAGAATACAACTATGGAACAATGGA AAGTTACCAGACAGAAGCTCCTAGGCATGTTTCTGGGACAAATGAGCCAAATCCAGTTGAAGAAATATTT ACTGAAGAATATCTAACGGGAGAGGATTATGATTCCCAGAGGAAAAATTCTGAGGATACACTATATGAAA ACAAAGAAATAGACGGCAGGGATTCTGATCTTCTGGTAGATGGAGATTTAGGCGAATATGATTTTTATGA ATATAAAGAATATGAAGATAAACCAACAAGCCCCCCTAATGAAGAATTTGGTCCAGGTGTACCAGCAGAA ACTGATATTACAGAAACAAGCATAAATGGCCATGGTGCATATGGAGAGAAAGGACAGAAAGGAGAACCAG CAGTGGTTGAGCCTGGTATGCTTGTCGAAGGACCACCAGGACCAGCAGGACCTGCAGGTATTATGGGTCC TCCAGGTCTACAAGGCCCCACTGGACCCCCTGGTGACCCTGGCGATAGGGGCCCCCCAGGACGTCCTGGC TTACCAGGGGCTGATGGTCTACCTGGTCCTCCTGGTACTATGTTGATGTTACCGTTCCGTTATGGTGGTG ATGGTTCCAAAGGACCAACCATCTCTGCTCAGGAAGCTCAGGCTCAAGCTATTCTTCAGCAGGCTCGGAT TGCTCTGAGAGGCCCACCTGGCCCAATGGGTCTAACTGGAAGACCAGGTCCTGTGGGGGGGCCTGGTTCA TCTGGGGCCAAAGGTGAGAGTGGTGATCCAGGTCCTCAGGGCCCTCGAGGCGTCCAGGGTCCCCCTGGTC CAACGGGAAAACCTGGAAAAAGGGGTCGTCCAGGTGCAGATGGAGGAAGAGGAATGCCAGGAGAACCTGG GGCAAAGGGAGATCGAGGGTTTGATGGACTTCCGGGTCTGCCAGGTGACAAAGGTCACAGGGGTGAACGA GGTCCTCAAGGTCCTCCAGGTCCTCCTGGTGATGATGGAATGAGGGGAGAAGATGGAGAAATTGGACCAA GAGGTCTTCCAGGTGAAGCTGGCCCACGAGGTTTGCTGGGTCCAAGGGGAACTCCAGGAGCTCCAGGGCA GCCTGGTATGGCAGGTGTAGATGGCCCCCCAGGACCAAAAGGGAACATGGGTCCCCAAGGGGAGCCTGGG CCTCCAGGTCAACAAGGGAATCCAGGACCTCAGGGTCTTCCTGGTCCACAAGGTCCAATTGGTCCTCCTG GTGAAAAAGGACCACAAGGAAAACCAGGACTTGCTGGACTTCCTGGTGCTGATGGGCCTCCTGGTCATCC TGGGAAAGAAGGCCAGTCTGGAGAAAAGGGGGCTCTGGGTCCCCCTGGTCCACAAGGTCCTATTGGATAC CCGGGCCCCCGGGGAGTAAAGGGAGCAGATGGTGTCAGAGGTCTCAAGGGATCTAAAGGTGAAAAGGGTG AAGATGGTTTTCCAGGATTCAAAGGTGACATGGGTCTAAAAGGTGACAGAGGAGAAGTTGGTCAAATTGG CCCAAGAGGGGAAGATGGCCCTGAAGGACCCAAAGGTCGAGCAGGCCCAACTGGAGACCCAGGTCCTTCA GGTCAAGCAGGAGAAAAGGGAAAACTTGGAGTTCCAGGATTACCAGGATATCCAGGAAGACAAGGTCCAA AGGGTTCCACTGGATTCCCTGGGTTTCCAGGTGCCAATGGAGAGAAAGGTGCACGGGGAGTAGCTGGCAA ACCAGGCCCTCGGGGTCAGCGTGGTCCAACGGGTCCTCGAGGTTCAAGAGGTGCAAGAGGTCCCACTGGG AAACCTGGGCCAAAGGGCACTTCAGGTGGCGATGGCCCTCCTGGCCCTCCAGGTGAAAGAGGTCCTCAAG GACCTCAGGGTCCAGTTGGATTCCCTGGACCAAAAGGCCCTCCTGGACCACCTGGGAAGGATGGGCTGCC AGGACACCCTGGGCAACGTGGGGAGACTGGATTTCAAGGCAAGACCGGCCCTCCTGGGCCAGGGGGAGTG GTTGGACCACAGGGACCAACCGGTGAGACTGGTCCAATAGGGGAACGTGGGCATCCTGGCCCTCCTGGCC CTCCTGGTGAGCAAGGTCTTCCTGGTGCTGCAGGAAAAGAAGGTGCAAAGGGTGATCCAGGTCCTCAAGG TATCTCAGGGAAAGATGGACCAGCAGGATTACGTGGTTTCCCAGGGGAAAGAGGTCTTCCTGGAGCTCAG GGTGCACCTGGACTGAAAGGAGGGGAAGGTCCCCAGGGCCCACCAGGTCCAGTTGGCTCACCAGGAGAAC GTGGGTCAGCAGGTACAGCTGGCCCAATTGGTTTACCAGGGCGCCCGGGACCTCAGGGTCCTCCTGGTCC AGCTGGAGAGAAAGGTGCTCCTGGAGAAAAAGGTCCCCAAGGGCCTGCAGGGAGAGATGGAGTTCAAGGT CCTGTTGGTCTCCCAGGGCCAGCTGGTCCTGCCGGCTCCCCTGGGGAAGACGGAGACAAGGGTGAAATTG GTGAGCCGGGACAAAAAGGCAGCAAGGGTGACAAGGGAGAAAATGGCCCTCCCGGTCCCCCAGGTCTTCA AGGACCAGTTGGTGCCCCTGGAATTGCTGGAGGTGATGGTGAACCAGGTCCTAGAGGACAGCAGGGGATG TTTGGGCAAAAAGGTGATGAGGGTGCCAGAGGCTTCCCTGGACCTCCTGGTCCAATAGGTCTTCAGGGTC TGCCAGGCCCACCTGGTGAAAAAGGTGAAAATGGGGATGTTGGTCCCATGGGGCCACCTGGTCCTCCAGG CCCAAGAGGCCCTCAAGGTCCCAATGGAGCTGATGGACCACAAGGACCCCCAGGGTCTGTTGGTTCAGTT GGTGGTGTTGGAGAAAAGGGTGAACCTGGAGAAGCAGGGAACCCAGGGCCTCCTGGGGAAGCAGGTGTAG GCGGTCCCAAAGGAGAAAGAGGAGAGAAAGGGGAAGCTGGTCCACCTGGAGCTGCTGGACCTCCAGGTGC CAAGGGGCCACCAGGTGATGATGGCCCTAAGGGTAACCCGGGTCCTGTTGGTTTTCCTGGAGATCCTGGT CCTCCTGGGGAACCTGGCCCTGCAGGTCAAGATGGTGTTGGTGGTGACAAGGGTGAAGATGGAGATCCTG GTCAACCGGGTCCTCCTGGCCCATCTGGTGAGGCTGGCCCACCAGGTCCTCCTGGAAAACGAGGTCCTCC TGGAGCTGCAGGTGCAGAGGGAAGACAAGGTGAAAAAGGTGCTAAGGGGGAAGCAGGTGCAGAAGGTCCT CCTGGAAAAACCGGCCCAGTCGGTCCTCAGGGACCTGCAGGAAAGCCTGGTCCAGAAGGTCTTCGGGGCA TCCCTGGTCCTGTGGGAGAACAAGGTCTCCCTGGAGCTGCAGGCCAAGATGGACCACCTGGTCCTATGGG ACCTCCTGGCTTACCTGGTCTCAAAGGTGACCCTGGCTCCAAGGGTGAAAAGGGACATCCTGGTTTAATT GGCCTGATTGGTCCTCCAGGAGAACAAGGGGAAAAAGGTGACCGAGGGCTCCCTGGAACTCAAGGATCTC CAGGAGCAAAAGGGGATGGGGGAATTCCTGGTCCTGCTGGTCCCTTAGGTCCACCTGGTCCTCCAGGTTT ACCAGGTCCTCAAGGCCCAAAGGGTAACAAAGGCTCTACTGGACCCGCTGGCCAGAAAGGTGACAGTGGT CTTCCAGGGCCTCCTGGGTCTCCAGGTCCACCTGGTGAAGTCATTCAGCCTTTACCAATCTTGTCCTCCA AAAAAACGAGAAGACATACTGAAGGCATGCAAGCAGATGCAGATGATAATATTCTTGATTACTCGGATGG AATGGAAGAAATATTTGGTTCCCTCAATTCCCTGAAACAAGACATTGAGCATATGAAATTTCCAATGGGT ACTCAGACCAATCCAGCCCGAACTTGTAAAGACCTGCAACTCAGCCATCCTGACTTCCCAGATGGTGAAT ATTGGATTGATCCTAACCAAGGTTGCTCAGGAGATTCCTTCAAAGTTTACTGTAATTTCACATCTGGTGG TGAGACTTGCATTTATCCAGACAAAAAATCTGAGGGAGTAAGAATTTCATCATGGCCAAAGGAGAAACCA GGAAGTTGGTTTAGTGAATTTAAGAGGGGAAAACTGCTTTCATACTTAGATGTTGAAGGAAATTCCATCA ATATGGTGCAAATGACATTCCTGAAACTTCTGACTGCCTCTGCTCGGCAAAATTTCACCTACCACTGTCA TCAGTCAGCAGCCTGGTATGATGTGTCATCAGGAAGTTATGACAAAGCACTTCGCTTCCTGGGATCAAAT GATGAGGAGATGTCCTATGACAATAATCCTTTTATCAAAACACTGTATGATGGTTGTGCGTCCAGAAAAG GCTATGAAAAGACTGTCATTGAAATCAATACACCAAAAATTGATCAAGTACCTATTGTTGATGTCATGAT CAATGACTTTGGTGATCAGAATCAGAAGTTCGGATTTGAAGTTGGTCCTGTTTGTTTTCTTGGCTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_080629 |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_080629.2, NP_542196.2 |
RefSeq Size | 7327 bp |
RefSeq ORF | 5457 bp |
Locus ID | 1301 |
Cytogenetics | 1p21.1 |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
Gene Summary | 'This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]' Transcript Variant: This variant (B) utilizes alternate exon 6, designated exon 6B, and encodes the longest isoform (B). There are no publicly available transcripts representing this variant; it is supported by mRNA annotation on DNA accession AF101112.1, protein AAF04726.1, submitted by the authors of PMID:10486316. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
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