NCOA1 (NM_147233) Human Untagged Clone

CAT#: SC309595

NCOA1 (untagged)-Human nuclear receptor coactivator 1 (NCOA1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCOA1
• Synonyms: bHLHe42; bHLHe74; F-SRC-1; KAT13A; RIP160; SRC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_147233 edited
  CCGGGAAGCTACCCTCTGGAACTCAAGATTTGACCATATCTGTTTTGAGGATTCATTATG
  AACAAAGAAGTCTCCCAGGTGTGAAGTTTTTCAACATGAGTGGCCTCGGGGACAGTTCAT
  CCGACCCTGCTAACCCAGACTCACATAAGAGGAAAGGATCGCCATGTGACACACTGGCAT
  CAAGCACGGAAAAGAGGCGCAGGGAGCAAGAAAATAAATATTTAGAAGAACTAGCTGAGT
  TACTGTCTGCCAACATTAGTGACATTGACAGCTTGAGTGTAAAACCAGACAAATGCAAGA
  TTTTGAAGAAAACAGTCGATCAGATACAGCTAATGAAGAGAATGGAACAAGAGAAATCAA
  CAACTGATGACGATGTACAGAAATCAGACATCTCATCAAGTAGTCAAGGAGTGATAGAAA
  AGGAATCCTTGGGACCTCTTCTTTTGGAGGCTTTGGATGGATTTTTCTTTGTTGTGAACT
  GTGAAGGGAGAATTGTATTTGTGTCAGAGAATGTAACCAGCTACTTAGGTTACAATCAGG
  AGGAATTAATGAATACCAGCGTCTACAGCATACTGCACGTGGGGGATCATGCAGAATTTG
  TGAAGAATCTGCTACCAAAATCACTAGTAAATGGAGTTCCTTGGCCTCAAGAGGCAACAC
  GACGAAATAGCCATACCTTTAACTGCAGGATGCTAATTCACCCTCCAGATGAGCCAGGGA
  CCGAGAACCAAGAAGCTTGCCAGCGTTATGAAGTAATGCAGTGTTTCACTGTGTCACAGC
  CAAAATCAATTCAAGAGGATGGAGAAGATTTCCAGTCATGTCTGATTTGTATTGCACGGC
  GATTACCTCGGCCTCCAGCTATTACGGGTGTAGAATCCTTTATGACCAAGCAAGATACTA
  CAGGTAAAATCATCTCTATTGATACTAGTTCCCTGAGAGCTGCTGGCAGAACTGGTTGGG
  AAGATTTAGTGAGGAAGTGCATTTATGCTTTTTTCCAACCTCAGGGCAGAGAACCATCTT
  ATGCCAGACAGCTGTTCCAAGAAGTGATGACTCGTGGCACTGCCTCCAGCCCCTCCTATA
  GATTCATATTGAATGATGGGACAATGCTTAGCGCCCACACCAAGTGTAAACTTTGCTACC
  CTCAAAGTCCAGACATGCAACCTTTCATCATGGGAATTCATATCATCGACAGGGAGCACA
  GTGGGCTTTCTCCTCAAGATGACACTAATTCTGGAATGTCAATTCCCCGAGTAAATCCCT
  CGGTCAATCCTAGTATCTCTCCAGCTCATGGTGTGGCTCGTTCATCCACATTGCCACCAT
  CCAACAGCAACATGGTATCCACCAGAATAAACCGCCAGCAGAGCTCAGACCTTCATAGCA
  GCAGTCATAGTAATTCTAGCAACAGCCAAGGAAGTTTCGGATGCTCACCCGGAAGTCAGA
  TTGTAGCCAATGTTGCCTTAAACCAAGGACAGGCCAGTTCACAGAGCAGTAATCCCTCTT
  TAAACCTCAATAATTCTCCTATGGAAGGTACAGGAATATCCCTAGCACAGTTCATGTCTC
  CAAGGAGACAGGTTACTTCTGGATTGGCAACAAGGCCCAGGATGCCAAACAATTCCTTTC
  CTCCTAATATTTCGACATTAAGCTCTCCCGTTGGCATGACAAGTAGTGCCTGTAATAATA
  ATAACCGATCTTATTCAAACATCCCAGTAACATCTTTACAGGGTATGAATGAAGGACCCA
  ATAACTCCGTTGGCTTCTCTGCCAGTTCTCCAGTCCTCAGGCAGATGAGCTCACAGAATT
  CACCTAGCAGATTAAATATACAACCAGCAAAAGCTGAGTCCAAAGATAACAAAGAGATTG
  CCTCAATTTTAAATGAAATGATTCAATCTGACAACAGCTCTAGTGATGGCAAACCTCTGG
  ATTCAGGGCTTCTGCATAACAATGACAGACTTTCAGATGGAGACAGTAAATACTCTCAAA
  CCAGTCACAAACTAGTGCAGCTTTTGACAACAACTGCCGAACAGCAGTTACGGCATGCTG
  ATATAGACACAAGCTGCAAAGATGTCCTGTCTTGCACAGGCACTTCCAACTCTGCCTCTG
  CTAACTCTTCAGGAGGTTCTTGTCCCTCTTCTCATAGCTCATTGACAGAACGGCATAAAA
  TTCTACACCGGCTCTTACAGGAGGGTAGCCCCTCAGATATCACCACTTTGTCTGTCGAGC
  CTGATAAAAAGGACAGTGCATCTACTTCTGTGTCAGTGACTGGACAGGTACAAGGAAACT
  CCAGTATAAAACTAGAACTGGATGCTTCAAAGAAAAAAGAATCAAAAGACCATCAGCTCC
  TACGCTATCTTTTAGATAAAGATGAGAAAGATTTAAGATCAACTCCAAACCTGAGCCTGG
  ATGATGTAAAGGTGAAAGTGGAAAAGAAAGAACAGATGGATCCATGTAATACAAACCCAA
  CCCCAATGACCAAACCCACTCCTGAGGAAATAAAACTGGAGGCCCAGAGCCAGTTTACAG
  CTGACCTTGACCAGTTTGATCAGTTACTGCCCACGCTGGAGAAGGCAGCACAGTTGCCAG
  GCTTATGTGAGACAGACAGGATGGATGGTGCGGTCACCAGTGTAACCATCAAATCGGAGA
  TCCTGCCAGCTTCACTTCAGTCCGCCACTGCCAGACCCACTTCCAGGCTAAATAGATTAC
  CTGAGCTGGAATTGGAAGCAATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGA
  TTCCATGGACAAATAATACAGTGACAGCTATAAATCAGAGTAAATCAGAAGACCAGTGTA
  TTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATG
  AGAAGGCTCTTCTTGAACAGCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAG
  CTGAACTAGACAGAGCTCTGGGAATTGACAAACTTGTTCAGGGGGGTGGATTAGATGTAT
  TATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCA
  ACCTTTATTCCCAGCCTTACTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCC
  AAGGCATGGTCAGGCAAAAACCTTCACTGGGGACGATGCCTGTTCAAGTAACACCTCCCC
  GAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGG
  CTGCACCTAACCAGCTTCGACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGA
  TACACCAAAATCGGCAAGCTATCTTAAACCAGTTTGCAGCAACTGCTCCTGTTGGCATCA
  ATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGT
  TGGCACAACGTCAGCGGGAACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGC
  AGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTTGGGAACAACCTCCCTCCCTCATCTG
  GACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCT
  ATCCACCAAACTATGGTACAAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCAC
  AACTAGCAGCAAATCCTGAAGCATCCTTGGCCAACCGCAACAGCATGGTGAGCAGAGGCA
  TGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATG
  TCTTCCAGTATCCAGGAGCAGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTC
  TAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATCCCTCCTCCTCAGAGTTCTCTGCTCC
  AGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAG
  CGATAGGAAACAACAATGTGTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGC
  CAGGAGTATACAACAACATGAGCATCACCGTTTCCATGGCAGGTGGAAATACGAATGTTC
  AGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGA
  ACACTGTGTGCCCTGAGCAGATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCA
  ACCAGCTCTCATCCACTGACCTTCTCAAAACAGAAGCAGATGGAACCCAG::G:TGCAAC
  AGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACC
  TGAACCAGCCTGGTCCACTGGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGG
  CCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACTGAATAACCACTTTTAAAGGAATGTG
  AAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTT
  TGATATCTCAATCTGCAGCCATTCTTCAGGTCGTTGTGATTAAGGGCGAATTCTGCAGAT
  ATCCATCACACTGGCGGCCGCTCGAGCATGCATCTAGATT
  
• Restriction Sites: Please inquire
• ACCN: NM_147233
• ORF Size: 4323 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_147233.2.

Reference Data

• RefSeq: NM_147233.2, NP_671766.1
• RefSeq Size: 6892
• RefSeq ORF: 4323
• Locus ID: 8648
• Domains: PAS, HLH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3), also known as SRC(-Q), uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a protein (isoform 3) that lacks a single amino acid, compared to isoform 1.