NFAT5 (NM_138713) Human Untagged Clone

CAT#: SC309615

NFAT5 (untagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFAT5
• Synonyms: NF-AT5; NFATL1; NFATZ; OREBP; TONEBP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_138713, the custom clone sequence may differ by one or more nucleotides
  ATGCCCTCGGACTTCATCTCATTGCTCAGCGCGGACCTAGACCTGGAATCGCCCAAGTCC
  CTCTACTCGCGAGATTCTCTGAAGTTACACCCATCACAGAATTTTCATAGAGCTGGACTA
  TTGGAAGAATCTGTCTATGATCTTCTCCCAAAGGAGTTACAGTTACCTCCATCTAGAGAA
  ACATCTGTAGCATCAATGAGTCAGACAAGCGGTGGTGAGGCAGGCTCGCCTCCTCCAGCT
  GTTGTTGCTGCTGATGCTTCTTCAGCTCCCTCCTCTTCCTCCATGGGCGGTGCTTGCAGC
  TCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCAGTCACCGACAGCAAGGCT
  ATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAACAGAGGGGTAAGTGAAAAG
  CAGTTAACCAGTAACACAGTTCAGCAGCATCCATCAACACCGAAGAGGCACACAGTCTTG
  TACATCTCACCACCACCTGAGGACTTGCTGGATAACAGTCGGATGTCCTGCCAGGATGAG
  GGGTGTGGATTGGAATCTGAGCAGAGCTGCAGTATGTGGATGGAGGATTCCCCCTCCAAC
  TTCAGTAACATGAGCACCAGTTCCTACAATGATAACACTGAGGTACCTCGTAAATCACGA
  AAACGAAATCCAAAGCAGAGGCCGGGGGTCAAACGACGAGATTGTGAAGAATCTAATATG
  GATATATTTGATGCCGACAGTGCCAAAGCACCTCACTATGTGCTTTCTCAGCTTACCACG
  GACAACAAAGGCAACTCAAAAGCGGGAAATGGAACATTGGAAAACCAAAAAGGAACTGGA
  GTAAAGAAGAGCCCTATGTTGTGTGGACAATATCCTGTTAAAAGTGAGGGAAAGGAGCTG
  AAGATAGTTGTACAACCTGAGACACAGCACCGAGCTCGGTACCTGACTGAGGGCAGCCGT
  GGCTCAGTGAAAGATAGAACACAGCAAGGCTTTCCTACAGTAAAGCTGGAAGGCCATAAT
  GAACCTGTAGTGTTGCAAGTGTTTGTGGGCAACGACTCTGGACGAGTGAAACCACATGGA
  TTTTATCAGGCCTGCAGAGTAACTGGACGAAATACAACTCCTTGCAAAGAAGTGGACATT
  GAAGGCACTACTGTTATAGAAGTCGGCCTTGATCCTAGCAACAACATGACACTGGCGGTG
  GACTGCGTAGGGATATTGAAATTGAGGAATGCTGATGTCGAAGCCAGAATAGGAATTGCT
  GGTTCCAAGAAGAAAAGCACTCGTGCCAGATTGGTTTTTCGAGTTAATATCATGAGGAAA
  GATGGCTCCACTTTGACACTGCAAACACCCTCTTCTCCAATTTTGTGTACTCAGCCAGCA
  GGAGTGCCAGAAATCTTAAAGAAAAGCTTGCATAGCTGTTCAGTGAAAGGAGAAGAAGAA
  GTGTTTTTAATCGGCAAGAACTTTCTGAAAGGAACTAAAGTTATTTTCCAAGAAAATGTT
  TCTGATGAAAACTCTTGGAAGTCAGAAGCTGAAATTGATATGGAACTATTTCATCAGAAT
  CATCTTATTGTGAAGGTTCCTCCCTATCATGACCAACATATAACTTTGCCTGTGTCAGTG
  GGAATATATGTAGTGACAAATGCTGGAAGATCTCATGATGTTCAACCATTCACTTACACT
  CCAGACCCAGCAGCAGCTGGTGCTTTGAATGTAAATGTGAAGAAGGAAATATCTAGTCCA
  GCAAGACCTTGCTCTTTTGAAGAGGCCATGAAAGCAATGAAAACTACTGGATGTAATTTA
  GATAAGGTAAATATTATCCCTAATGCCCTGATGACTCCACTCATACCAAGCAGTATGATT
  AAGAGTGAAGATGTTACTCCAATGGAAGTAACAGCAGAAAAAAGATCTTCCACTATTTTT
  AAGACTACAAAGTCTGTTGGATCAACTCAGCAAACATTAGAAAACATCTCAAACATAGCA
  GGAAATGGCTCTTTTTCATCACCATCATCTTCCCACCTACCTTCTGAAAATGAAAAACAG
  CAGCAGATTCAGCCCAAGGCATACAACCCAGAGACCCTGACAACTATTCAAACCCAGGAC
  ATCTCACAGCCTGGTACTTTTCCAGCAGTTTCTGCTTCTAGTCAGCTGCCCAACAGCGAT
  GCACTATTGCAGCAGGCTACACAGTTTCAGACAAGAGAAACTCAGTCTAGAGAGATATTA
  CAGTCAGATGGTACAGTGGTTAATTTGTCACAACTGACTGAGGCATCACAACAACAGCAG
  CAGTCACCACTACAAGAACAAGCACAGACTTTACAGCAGCAGATTTCATCAAATATTTTT
  CCATCACCAAATAGTGTGAGTCAGCTTCAGAATACTATTCAGCAGCTGCAAGCAGGGAGT
  TTCACAGGCAGTACTGCTAGTGGCAGCAGTGGAAGTGTTGACTTGGTCCAACAAGTTTTA
  GAGGCACAGCAGCAGTTATCTTCAGTTTTATTTTCTGCTCCAGATGGTAATGAGAATGTT
  CAAGAGCAGCTTAGTGCAGATATTTTTCAACAAGTCAGTCAAATTCAGAGTGGTGTAAGC
  CCTGGAATGTTTTCCTCAACAGAGCCAACAGTCCATACCAGACCAGATAATTTATTACCT
  GGAAGAGCTGAAAGTGTTCATCCACAGTCTGAAAACACGTTATCTAATCAACAGCAGCAG
  CAGCAGCAGCAACAGCAAGTGATGGAATCTTCAGCCGCAATGGTGATGGAGATGCAACAG
  AGTATCTGCCAGGCAGCTGCCCAGATTCAGTCAGAGTTATTCCCTTCAACTGCTTCAGCA
  AATGGAAACCTTCAGCAATCGCCAGTTTACCAGCAGACTTCTCACATGATGAGTGCATTG
  TCTACCAATGAGGATATGCAAATGCAGTGTGAATTGTTTTCTTCTCCTCCTGCAGTTTCT
  GGAAATGAAACTTCTACAACTACCACACAGCAGGTTGCAACCCCTGGCACTACCATGTTT
  CAGACATCAAGTTCAGGAGATGGAGAAGAAACTGGAACACAAGCAAAACAGATTCAGAAC
  AGTGTCTTTCAGACCATGGTCCAAATGCAACATAGTGGGGACAATCAACCTCAAGTTAAC
  CTTTTTTCATCCACAAAAAGTATGATGAGTGTTCAGAATAGTGGTACCCAACAACAAGGT
  AATGGTTTATTCCAGCAAGGGAATGAGATGATGTCACTTCAATCTGGAAATTTTTTGCAG
  CAGTCTTCTCATTCACAGGCCCAACTTTTTCATCCTCAAAATCCTATTGCCGATGCTCAG
  AACCTTTCCCAGGAAACTCAAGGTTCTCTCTTTCATAGTCCAAATCCTATTGTCCACAGT
  CAGACTTCTACAACCTCCTCTGAACAAATGCAGCCTCCAATGTTTCACTCTCAAAGTACC
  ATTGCTGTGTTACAGGGCTCTTCAGTTCCTCAAGACCAGCAGTCAACCAACATATTTCTT
  TCCCAGAGTCCCATGAATAATCTTCAGACTAACACAGTAGCCCAAGAAGCATTTTTTGCA
  GCACCGAACTCAATTTCTCCACTTCAGTCAACATCAAACAGTGAACAACAAGCTGCTTTC
  CAACAGCAAGCTCCAATATCACACATCCAGACTCCTATGCTTTCCCAAGAACAGGCACAA
  CCCCCGCAGCAGGGTTTATTTCAGCCTCAGGTGGCCCTGGGCTCCCTTCCACCTAATCCA
  ATGCCTCAAAGCCAACAAGGAACCATGTTCCAGTCACAGCACTCAATAGTTGCCATGCAG
  AGTAACTCTCCATCCCAGGAACAGCAGCAGCAGCAGCAACAGCAGCAGCAACAGCAGCAG
  CAACAACAACAGAGCATTTTATTCAGTAATCAGAATACCATGGCTACAATGGCGTCTCCA
  AAGCAACCACCACCAAACATGATATTCAACCCAAATCAAAATCCAATGGCTAATCAGGAG
  CAACAGAACCAGTCAATTTTTCACCAACAAAGTAACATGGCCCCAATGAATCAAGAGCAA
  CAGCCCATGCAATTTCAGAGTCAGTCCACAGTTTCCTCACTTCAGAACCCAGGTCCTACC
  CAGTCGGAATCATCACAGACCCCCTTGTTCCATAGCTCTCCTCAGATTCAGTTGGTACAA
  GGGTCACCTAGTTCTCAAGAGCAGCAAGTAACTCTCTTCTTATCTCCAGCATCCATGTCT
  GCCTTGCAGACCAGTATAAATCAACAAGATATGCAACAGTCTCCTCTTTATTCCCCTCAG
  AACAACATGCCTGGAATTCAAGGAGCCACATCTTCGCCTCAACCACAGGCTACTTTATTT
  CACAACACAGCAGGAGGCACAATGAACCAACTGCAGAATTCTCCTGGCTCATCTCAGCAG
  ACATCAGGAATGTTCTTATTTGGCATTCAAAATAACTGTAGTCAGCTTTTAACCTCTGGA
  CCAGCTACATTGCCTGATCAGTTGATGGCCATAAGTCAGCCAGGCCAACCACAAAACGAG
  GGCCAGCCACCTGTGACAACACTTCTTTCTCAGCAAATGCCAGAGAATTCTCCACTGGCA
  TCCTCTATAAACACCAACCAGAACATCGAAAAGATTGATTTGCTTGTTTCATTGCAAAAC
  CAAGGGAACAACTTGACTGGCTCCTTTTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_138713
• ORF Size: 4650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_138713.2, NP_619727.2
• RefSeq Size: 14177
• RefSeq ORF: 4650
• Locus ID: 10725
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an exon in the 5' region, compared to variant 1. This difference causes translation initiation at an upstream start codon and results in an isoform (b) with a longer N-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.