Dicer (DICER1) (NM_177438) Human Untagged Clone

CAT#: SC309637

DICER1 (untagged)-Human dicer 1, ribonuclease type III (DICER1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DICER1
• Synonyms: DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_177438, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAAAGCCCTGCTTTGCAACCCCTCAGCATGGCAGGCCTGCAGCTCATGACCCCTGCTTCCTCACCAA
  TGGGTCCTTTCTTTGGACTGCCATGGCAACAAGAAGCAATTCATGATAACATTTATACGCCAAGAAAATA
  TCAGGTTGAACTGCTTGAAGCAGCTCTGGATCATAATACCATCGTCTGTTTAAACACTGGCTCAGGGAAG
  ACATTTATTGCAGTACTACTCACTAAAGAGCTGTCCTATCAGATCAGGGGAGACTTCAGCAGAAATGGAA
  AAAGGACGGTGTTCTTGGTCAACTCTGCAAACCAGGTTGCTCAACAAGTGTCAGCTGTCAGAACTCATTC
  AGATCTCAAGGTTGGGGAATACTCAAACCTAGAAGTAAATGCATCTTGGACAAAAGAGAGATGGAACCAA
  GAGTTTACTAAGCACCAGGTTCTCATTATGACTTGCTATGTCGCCTTGAATGTTTTGAAAAATGGTTACT
  TATCACTGTCAGACATTAACCTTTTGGTGTTTGATGAGTGTCATCTTGCAATCCTAGACCACCCCTATCG
  AGAAATTATGAAGCTCTGTGAAAATTGTCCATCATGTCCTCGCATTTTGGGACTAACTGCTTCCATTTTA
  AATGGGAAATGTGATCCAGAGGAATTGGAAGAAAAGATTCAGAAACTAGAGAAAATTCTTAAGAGTAATG
  CTGAAACTGCAACTGACCTGGTGGTCTTAGACAGGTATACTTCTCAGCCATGTGAGATTGTGGTGGATTG
  TGGACCATTTACTGACAGAAGTGGGCTTTATGAAAGACTGCTGATGGAATTAGAAGAAGCACTTAATTTT
  ATCAATGATTGTAATATATCTGTACATTCAAAAGAAAGAGATTCTACTTTAATTTCGAAACAGATACTAT
  CAGACTGTCGTGCCGTATTGGTAGTTCTGGGACCCTGGTGTGCAGATAAAGTAGCTGGAATGATGGTAAG
  AGAACTACAGAAATACATCAAACATGAGCAAGAGGAGCTGCACAGGAAATTTTTATTGTTTACAGACACT
  TTCCTAAGGAAAATACATGCACTATGTGAAGAGCACTTCTCACCTGCCTCACTTGACCTGAAATTTGTAA
  CTCCTAAAGTAATCAAACTGCTCGAAATCTTACGCAAATATAAACCATATGAGCGACAGCAGTTTGAAAG
  CGTTGAGTGGTATAATAATAGAAATCAGGATAATTATGTGTCATGGAGTGATTCTGAGGATGATGATGAG
  GATGAAGAAATTGAAGAAAAAGAGAAGCCAGAGACAAATTTTCCTTCTCCTTTTACCAACATTTTGTGCG
  GAATTATTTTTGTGGAAAGAAGATACACAGCAGTTGTCTTAAACAGATTGATAAAGGAAGCTGGCAAACA
  AGATCCAGAGCTGGCTTATATCAGTAGCAATTTCATAACTGGACATGGCATTGGGAAGAATCAGCCTCGC
  AACAAACAGATGGAAGCAGAATTCAGAAAACAGGAAGAGGTACTTAGGAAATTTCGAGCACATGAGACCA
  ACCTGCTTATTGCAACAAGTATTGTAGAAGAGGGTGTTGATATACCAAAATGCAACTTGGTGGTTCGTTT
  TGATTTGCCCACAGAATATCGATCCTATGTTCAATCTAAAGGAAGAGCAAGGGCACCCATCTCTAATTAT
  ATAATGTTAGCGGATACAGACAAAATAAAAAGTTTTGAAGAAGACCTTAAAACCTACAAAGCTATTGAAA
  AGATCTTGAGAAACAAGTGTTCCAAGTCGGTTGATACTGGTGAGACTGACATTGATCCTGTCATGGATGA
  TGATGACGTTTTCCCACCATATGTGTTGAGGCCTGACGATGGTGGTCCACGAGTCACAATCAACACGGCC
  ATTGGACACATCAATAGATACTGTGCTAGATTACCAAGTGATCCGTTTACTCATCTAGCTCCTAAATGCA
  GAACCCGAGAGTTGCCTGATGGTACATTTTATTCAACTCTTTATCTGCCAATTAACTCACCTCTTCGAGC
  CTCCATTGTTGGTCCACCAATGAGCTGTGTACGATTGGCTGAAAGAGTTGTAGCTCTCATTTGCTGTGAG
  AAACTGCACAAAATTGGCGAACTGGATGACCATTTGATGCCAGTTGGGAAAGAGACTGTTAAATATGAAG
  AGGAGCTTGATTTGCATGATGAAGAAGAGACCAGTGTTCCAGGAAGACCAGGTTCCACGAAACGAAGGCA
  GTGCTACCCAAAAGCAATTCCAGAGTGTTTGAGGGATAGTTATCCCAGACCTGATCAGCCCTGTTACCTG
  TATGTGATAGGAATGGTTTTAACTACACCTTTACCTGATGAACTCAACTTTAGAAGGCGGAAGCTCTATC
  CTCCTGAAGATACCACAAGATGCTTTGGAATACTGACGGCCAAACCCATACCTCAGATTCCACACTTTCC
  TGTGTACACACGCTCTGGAGAGGTTACCATATCCATTGAGTTGAAGAAGTCTGGTTTCATGTTGTCTCTA
  CAAATGCTTGAGTTGATTACAAGACTTCACCAGTATATATTCTCACATATTCTTCGGCTTGAAAAACCTG
  CACTAGAATTTAAACCTACAGACGCTGATTCAGCATACTGTGTTCTACCTCTTAATGTTGTTAATGACTC
  CAGCACTTTGGATATTGACTTTAAATTCATGGAAGATATTGAGAAGTCTGAAGCTCGCATAGGCATTCCC
  AGTACAAAGTATACAAAAGAAACACCCTTTGTTTTTAAATTAGAAGATTACCAAGATGCCGTTATCATTC
  CAAGATATCGCAATTTTGATCAGCCTCATCGATTTTATGTAGCTGATGTGTACACTGATCTTACCCCACT
  CAGTAAATTTCCTTCCCCTGAGTATGAAACTTTTGCAGAATATTATAAAACAAAGTACAACCTTGACCTA
  ACCAATCTCAACCAGCCACTGCTGGATGTGGACCACACATCTTCAAGACTTAATCTTTTGACACCTCGAC
  ATTTGAATCAGAAGGGGAAAGCGCTTCCTTTAAGCAGTGCTGAGAAGAGGAAAGCCAAATGGGAAAGTCT
  GCAGAATAAACAGATACTGGTTCCAGAACTCTGTGCTATACATCCAATTCCAGCATCACTGTGGAGAAAA
  GCTGTTTGTCTCCCCAGCATACTTTATCGCCTTCACTGCCTTTTGACTGCAGAGGAGCTAAGAGCCCAGA
  CTGCCAGCGATGCTGGCGTGGGAGTCAGATCACTTCCTGCGGATTTTAGATACCCTAACTTAGACTTCGG
  GTGGAAAAAATCTATTGACAGCAAATCTTTCATCTCAATTTCTAACTCCTCTTCAGCTGAAAATGATAAT
  TACTGTAAGCACAGCACAATTGTCCCTGAAAATGCTGCACATCAAGGTGCTAATAGAACCTCCTCTCTAG
  AAAATCATGACCAAATGTCTGTGAACTGCAGAACGTTGCTCAGCGAGTCCCCTGGTAAGCTCCACGTTGA
  AGTTTCAGCAGATCTTACAGCAATTAATGGTCTTTCTTACAATCAAAATCTCGCCAATGGCAGTTATGAT
  TTAGCTAACAGAGACTTTTGCCAAGGAAATCAGCTAAATTACTACAAGCAGGAAATACCCGTGCAACCAA
  CTACCTCATATTCCATTCAGAATTTATACAGTTACGAGAACCAGCCCCAGCCCAGCGATGAATGTACTCT
  CCTGAGTAATAAATACCTTGATGGAAATGCTAACAAATCTACCTCAGATGGAAGTCCTGTGATGGCCGTA
  ATGCCTGGTACGACAGACACTATTCAAGTGCTCAAGGGCAGGATGGATTCTGAGCAGAGCCCTTCTATTG
  GGTACTCCTCAAGGACTCTTGGCCCCAATCCTGGACTTATTCTTCAGGCTTTGACTCTGTCAAACGCTAG
  TGATGGATTTAACCTGGAGCGGCTTGAAATGCTTGGCGACTCCTTTTTAAAGCATGCCATCACCACATAT
  CTATTTTGCACTTACCCTGATGCGCATGAGGGCCGCCTTTCATATATGAGAAGCAAAAAGGTCAGCAACT
  GTAATCTGTATCGCCTTGGAAAAAAGAAGGGACTACCCAGCCGCATGGTGGTGTCAATATTTGATCCCCC
  TGTGAATTGGCTTCCTCCTGGTTATGTAGTAAATCAAGACAAAAGCAACACAGATAAATGGGAAAAAGAT
  GAAATGACAAAAGACTGCATGCTGGCGAATGGCAAACTGGATGAGGATTACGAGGAGGAGGATGAGGAGG
  AGGAGAGCCTGATGTGGAGGGCTCCGAAGGAAGAGGCTGACTATGAAGATGATTTCCTGGAGTATGATCA
  GGAACATATCAGATTTATAGATAATATGTTAATGGGGTCAGGAGCTTTTGTAAAGAAAATCTCTCTTTCT
  CCTTTTTCAACCACTGATTCTGCATATGAATGGAAAATGCCCAAAAAATCCTCCTTAGGTAGTATGCCAT
  TTTCATCAGATTTTGAGGATTTTGACTACAGCTCTTGGGATGCAATGTGCTATCTGGATCCTAGCAAAGC
  TGTTGAAGAAGATGACTTTGTGGTGGGGTTCTGGAATCCATCAGAAGAAAACTGTGGTGTTGACACGGGA
  AAGCAGTCCATTTCTTACGACTTGCACACTGAGCAGTGTATTGCTGACAAAAGCATAGCGGACTGTGTGG
  AAGCCCTGCTGGGCTGCTATTTAACCAGCTGTGGGGAGAGGGCTGCTCAGCTTTTCCTCTGTTCACTGGG
  GCTGAAGGTGCTCCCGGTAATTAAAAGGACTGATCGGGAAAAGGCCCTGTGCCCTACTCGGGAGAATTTC
  AACAGCCAACAAAAGAACCTTTCAGTGAGCTGTGCTGCTGCTTCTGTGGCCAGTTCACGCTCTTCTGTAT
  TGAAAGACTCGGAATATGGTTGTTTGAAGATTCCACCAAGATGTATGTTTGATCATCCAGATGCAGATAA
  AACACTGAATCACCTTATATCGGGGTTTGAAAATTTTGAAAAGAAAATCAACTACAGATTCAAGAATAAG
  GCTTACCTTCTCCAGGCTTTTACACATGCCTCCTACCACTACAATACTATCACTGATTGTTACCAGCGCT
  TAGAATTCCTGGGAGATGCGATTTTGGACTACCTCATAACCAAGCACCTTTATGAAGACCCGCGGCAGCA
  CTCCCCGGGGGTCCTGACAGACCTGCGGTCTGCCCTGGTCAACAACACCATCTTTGCATCGCTGGCTGTA
  AAGTACGACTACCACAAGTACTTCAAAGCTGTCTCTCCTGAGCTCTTCCATGTCATTGATGACTTTGTGC
  AGTTTCAGCTTGAGAAGAATGAAATGCAAGGAATGGATTCTGAGCTTAGGAGATCTGAGGAGGATGAAGA
  GAAAGAAGAGGATATTGAAGTTCCAAAGGCCATGGGGGATATTTTTGAGTCGCTTGCTGGTGCCATTTAC
  ATGGATAGTGGGATGTCACTGGAGACAGTCTGGCAGGTGTACTATCCCATGATGCGGCCACTAATAGAAA
  AGTTTTCTGCAAATGTACCCCGTTCCCCTGTGCGAGAATTGCTTGAAATGGAACCAGAAACTGCCAAATT
  TAGCCCGGCTGAGAGAACTTACGACGGGAAGGTCAGAGTCACTGTGGAAGTAGTAGGAAAGGGGAAATTT
  AAAGGTGTTGGTCGAAGTTACAGGATTGCCAAATCTGCAGCAGCAAGAAGAGCCCTCCGAAGCCTCAAAG
  CTAATCAACCTCAGGTTCCCAATAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_177438
• ORF Size: 5769 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_177438.2, NP_803187.1
• RefSeq Size: 10323
• RefSeq ORF: 5769
• Locus ID: 23405
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
  Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Variants 1, 2, 4 and 5 encode the same isoform (1).