ACACB (NM_001093) Human Untagged Clone

CAT#: SC309874

ACACB (untagged)-Human acetyl-CoA carboxylase beta (ACACB)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACACB
• Synonyms: ACC2; ACCB; HACC275
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001093 edited
  GGCACCAGCCCCAGTGACGATTTTCTGAATGGTCTTGCTTCTTTGTCTATCTTGTCTGAT
  TTTCTCCTGTCTGACCTTTTCCTGGTTAAAAATCTGGGGGAAAATGACGGACTCCAAGCC
  GATCACCAAGAGTAAATCAGAAGCAAACCTCATCCCGAGCCAGGAGCCCTTTCCAGCCTC
  TGATAACTCAGGGGAGACACCGCAGAGAAATGGGGAGGGCCACACTCTGCCCAAGACACC
  CAGCCAGGCCGAGCCAGCCTCCCACAAAGGCCCCAAAGATGCCGGTCGGCGGAGAAACTC
  CCTACCACCCTCCCACCAGAAGCCCCCAAGAAACCCCCTTTCTTCCAGTGACGCAGCACC
  CTCCCCAGAGCTTCAAGCCAACGGGACTGGGACACAAGGTCTGGAGGCCACAGATACCAA
  TGGCCTGTCCTCCTCAGCCAGGCCCCAGGGCCAGCAAGCTGGCTCCCCCTCCAAAGAAGA
  CAAGAAGCAGGCAAACATCAAGAGGCAGCTGATGACCAACTTCATCCTGGGCTCTTTTGA
  TGACTACTCCTCCGACGAGGACTCTGTTGCTGGCTCATCTCGTGAGTCTACCCGGAAGGG
  CAGCCGGGCCAGCTTGGGGGCCCTGTCCCTGGAGGCTTATCTGACCACAGGTGAAGCTGA
  GACCCGCGTCCCCACTATGAGGCCGAGCATGTCGGGACTCCACCTGGTGAAGAGGGGACG
  GGAACACAAGAAGCTGGACCTGCACAGAGACTTTACCGTGGCTTCTCCCGCTGAGTTTGT
  CACACGCTTTGGGGGGGATCGGGTCATCGAGAAGGTGCTTATTGCCAACAACGGGATTGC
  CGCTGTGAAGTGCATGCGCTCCATCCGCAGGTGGGCCTATGAGATGTTCCGCAACGAGCG
  GGCCATCCGGTTTGTTGTGATGGTGACCCCCGAGGACCTTAAGGCCAACGCAGAGTACAT
  CAAGATGGCGGATCATTACGTCCCCGTCCCAGGAGGGCCCAATAACAACAACTATGCCAA
  CGTGGAGCTGATTGTGGACATTGCCAAGAGAATCCCCGTGCAGGCGGTGTGGGCTGGCTG
  GGGCCATGCTTCAGAAAACCCTAAACTTCCGGAGCTGCTGTGCAAGAATGGAGTTGCTTT
  CTTAGGCCCTCCCAGTGAGGCCATGTGGGCCTTAGGAGATAAGATCGCCTCCACCGTTGT
  CGCCCAGACGCTACAGGTCCCAACCCTGCCCTGGAGTGGAAGCGGCCTGACAGTGGAGTG
  GACAGAAGATGATCTGCAGCAGGGAAAAAGAATCAGTGTCCCAGAAGATGTTTATGACAA
  GGGTTGCGTGAAAGACGTAGATGAGGGCTTGGAGGCAGCAAAAAGAATTGGTTTTCCATT
  GATGATCAAAGCTTCTGAAGGTGGCGGAGGGAAGGGAATCCGGAAGGCTGAGAGTGCGGA
  GGACTTCCCGATCCTTTTCAGACAAGTACAGAGTGAGATCCCAGGCTCGCCCATCTTTCT
  CATGAAGCTGGCCCAGCACGCCCGTCACCTGGAAGTTCAGATCCTCGCTGACCAGTATGG
  GAATGCTGTGTCTCTGTTTGGTCGCGACTGCTCCATCCAGCGGCGGCATCAGAAGATCGT
  TGAGGAAGCACCGGCCACCATCGCCCCGCTGGCCATATTCGAGTTCATGGAGCAGTGTGC
  CATCCGCCTGGCCAAGACCGTGGGCTATGTGAGTGCAGGGACAGTGGAATACCTCTATAG
  TCAGGATGGCAGCTTCCACTTCTTGGAGCTGAATCCTCGCTTGCAGGTGGAACATCCCTG
  CACAGAAATGATTGCTGACGTTAATCTGCCGGCCGCCCAGCTACAGATCGCCATGGGCGT
  GCCACTGCACCGGCTGAAGGATATCCGGCTTCTGTATGGAGAGTCACCATGGGGAGTGAC
  TCCCATTTCTTTTGAAACCCCCTCAAACCCTCCCCTCGCCCGAGGCCACGTCATTGCCAC
  CAGAATCACCAGCGAAAACCCAGACGAGGGTTTTAAGCCGAGCTCCGGGACTGTCCAGGA
  ACTGAATTTCCGGAGCAGCAAGAACGTGTGGGGTTACTTCAGCGTGGCCGCTACTGGAGG
  CCTGCACGAGTTTGCGGATTCCCAATTTGGGCACTGCTTCTCCTGGGGAGAGAACCGGGA
  AGAGGCCATTTCGAACATGGTGGTGGCTTTGAAGGAACTGTCCATCCGAGGCGACTTTAG
  GACTACCGTGGAATACCTCATTAACCTCCTGGAGACCGAGAGCTTCCAGAACAACGACAT
  CGACACCGGGTGGTTGGACTACCTCATTGCTGAGAAAGTGCAGGCGGAGAAACCGGATAT
  CATGCTTGGGGTGGTATGCGGGGCCTTGAACGTGGCCGATGCGATGTTCAGAACGTGCAT
  GACAGATTTCTTACACTCCCTGGAAAGGGGCCAGGTCCTCCCAGCGGATTCACTACTGAA
  CCTCGTAGATGTGGAATTAATTTACGGAGGTGTTAAGTACATTCTCAAGGTGGCCCGGCA
  GTCTCTGACCATGTTCGTTCTCATCATGAATGGCTGCCACATCGAGATTGATGCCCACCG
  GCTGAATGATGGGGGGCTCCTGCTCTCCTACAATGGGAACAGCTACACCACCTACATGAA
  GGAAGAGGTTGACAGTTACCGAATTACCATCGGCAATAAGACGTGTGTGTTTGAGAAGGA
  GAACGATCCTACAGTCCTGAGATCCCCCTCGGCTGGGAAGCTGACACAGTACACAGTGGA
  GGATGGGGGCCACGTTGAGGCTGGGAGCAGCTACGCTGAGATGGAGGTGATGAAGATGAT
  CATGACCCTGAACGTTCAGGAAAGAGGCCGGGTGAAGTACATCAAGCGTCCAGGTGCCGT
  GCTGGAAGCAGGCTGCGTGGTGGCCAGGCTGGAGCTCGATGACCCTTCTAAAGTCCACCC
  GGCTGAACCGTTCACAGGAGAACTCCCTGCCCAGCAGACACTGCCCATCCTCGGAGAGAA
  ACTGCACCAGGTCTTCCACAGCGTCCTGGAAAACCTCACCAACGTCATGAGTGGCTTTTG
  TCTGCCAGAGCCCGTTTTTAGCATAAAGCTGAAGGAGTGGGTGCAGAAGCTCATGATGAC
  CCTCCGGCACCCGTCACTGCCGCTGCTGGAGCTGCAGGAGATCATGACCAGCGTGGCAGG
  CCGCATCCCCGCCCCTGTGGAGAAGTCTGTCCGCAGGGTGATGGCCCAGTATGCCAGCAA
  CATCACCTCGGTGCTGTGCCAGTTCCCCAGCCAGCAGATAGCCACCATCCTGGACTGCCA
  TGCAGCCACCCTGCAGCGGAAGGCTGATCGAGAGGTCTTCTTCATCAACACCCAGAGCAT
  CGTGCAGTTGGTCCAGAGATACCGCAGCGGGATCCGCGGCTATATGAAAACAGTGGTGTT
  GGATCTCCTGAGAAGATACTTGCGTGTTGAGCACCATTTTCAGCAAGCCCACTACGACAA
  GTGTGTGATAAACCTCAGGGAGCAGTTCAAGCCAGACATGTCCCAGGTGCTGGACTGCAT
  CTTCTCCCACGCACAGGTGGCCAAGAAGAACCAGCTGGTGATCATGTTGATCGATGAGCT
  GTGTGGCCCAGACCCTTCCCTGTCGGACGAGCTGATCTCCATCCTCAACGAGCTCACTCA
  GCTGAGCAAAAGCGAGCACTGCAAAGTGGCCCTCAGAGCCCGGCAGATCCTGATTGCCTC
  CCACCTCCCCTCCTACGAGCTGCGGCATAACCAGGTGGAGTCCATTTTCCTGTCTGCCAT
  TGACATGTACGGCCACCAGTTCTGCCCCGAGAACCTCAAGAAATTAATACTTTCGGAAAC
  AACCATCTTCGACGTCCTGCCTACTTTCTTCTATCACGCAAACAAAGTCGTGTGCATGGC
  GTCCTTGGAGGTTTACGTGCGGAGGGGCTACATCGCCTATGAGTTAAACAGCCTGCAGCA
  CCGGCAGCTCCCGGACGGCACCTGCGTGGTAGAATTCCAGTTCATGCTGCCGTCCTCCCA
  CCCAAACCGGATGACCGTGCCCATCAGCATCACCAACCCTGACCTGCTGAGGCACAGCAC
  AGAGCTCTTCATGGACAGCGGCTTCTCCCCACTGTGCCAGCGCATGGGAGCCATGGTAGC
  CTTCAGGAGATTCGAGGACTTCACCAGAAATTTTGATGAAGTCATCTCTTGCTTCGCCAA
  CGTGCCCAAAGACACCCCCCTCTTCAGCGAGGCCCGCACCTCCCTATACTCCGAGGATGA
  CTGCAAGAGCCTCAGAGAAGAGCCCATCCACATTCTGAATGTGTCCATCCAGTGTGCAGA
  CCACCTGGAGGATGAGGCACTGGTGCCGATTTTACGGACATTCGTACAGTCCAAGAAAAA
  TATCCTTGTGGATTATGGACTCCGACGAATCACATTCTTGATTGCCCAAGAGAAAGAATT
  TCCCAAGTTTTTCACATTCAGAGCAAGAGATGAGTTTGCAGAAGATCGCATTTACCGTCA
  CTTGGAACCTGCCCTGGCCTTCCAGCTGGAACTTAACCGGATGCGTAACTTCGATCTGAC
  CGCCGTGCCCTGTGCCAACCACAAGATGCACCTTTACCTGGGTGCTGCCAAGGTGAAGGA
  AGGTGTGGAAGTGACGGACCATAGGTTCTTCATCCGCGCCATCATCAGGCACTCTGACCT
  GATCACAAAGGAAGCCTCCTTCGAATACCTGCAGAACGAGGGTGAGCGGCTGCTCCTGGA
  GGCCATGGACGAGCTGGAGGTGGCGTTCAATAACACCAGCGTGCGCACCGACTGCAACCA
  CATCTTCCTCAACTTCGTGCCCACTGTCATCATGGACCCCTTCAAGATCGAGGAGTCCGT
  GCGCTACATGGTTATGCGCTACGGCAGCCGGCTGTGGAAACTCCGTGTGCTACAGGCTGA
  GGTCAAGATCAACATCCGCCAGACCACCACCGGCAGTGCCGTTCCCATCCGCCTGTTCAT
  CACCAATGAGTCGGGCTACTACCTGGACATCAGCCTCTACAAAGAAGTGACTGACTCCAG
  ATCTGGAAATATCATGTTTCACTCCTTCGGCAACAAGCAAGGGCCCCAGCACGGGATGCT
  GATCAATACTCCCTACGTCACCAAGGATCTGCTCCAGGCCAAGCGATTCCAGGCCCAGAC
  CCTGGGAACCACCTACATCTATGACTTCCCGGAAATGTTCAGGCAGGCTCTCTTTAAACT
  GTGGGGCTCCCCAGACAAGTATCCCAAAGACATCCTGACATACACTGAATTAGTGTTGGA
  CTCTCAGGGCCAGCTGGTGGAGATGAACCGACTTCCTGGTGGAAATGAGGTGGGCATGGT
  GGCCTTCAAAATGAGGTTTAAGACCCAGGAGTACCCGGAAGGACGGGATGTGATCGTCAT
  CGGCAATGACATCACCTTTCGCATTGGATCCTTTGGCCCTGGAGAGGACCTTCTGTACCT
  GCGGGCATCCGAGATGGCCCGGGCAGAGGGCATTCCCAAAATTTACGTGGCAGCCAACAG
  TGGCGCCCGTATTGGCATGGCAGAGGAGATCAAACACATGTTCCACGTGGCTTGGGTGGA
  CCCAGAAGACCCCCACAAAGGATTTAAATACCTGTACCTGACTCCCCAAGACTACACCAG
  AATCAGCTCCCTGAACTCCGTCCACTGTAAACACATCGAGGAAGGAGGAGAGTCCAGATA
  CATGATCACGGATATCATCGGGAAGGATGATGGCTTGGGCGTGGAGAATCTGAGGGGCTC
  AGGCATGATTGCTGGGGAGTCCTCTCTGGCTTACGAAGAGATCGTCACCATTAGCTTGGT
  GACCTGCCGAGCCATTGGGATTGGGGCCTACTTGGTGAGGCTGGGCCAGCGAGTGATCCA
  GGTGGAGAATTCCCACATCATCCTCACAGGAGCAAGTGCTCTCAACAAGGTCCTGGGAAG
  AGAGGTCTACACATCCAACAACCAGCTGGGTGGCGTTCAGATCATGCATTACAATGGTGT
  CTCCCACATCACCGTGCCAGATGACTTTGAGGGGGTTTATACCATCCTGGAGTGGCTGTC
  CTATATGCCAAAGGATAATCACAGCCCTGTCCCTATCATCACACCCACTGACCCCATTGA
  CAGAGAAATTGAATTCCTCCCATCCAGAGCTCCCTACGACCCCCGGTGGATGCTTGCAGG
  AAGGCCTCACCCAACTCTGAAGGGAACGTGGCAGAGCGGATTCTTTGACCATGGCAGTTT
  CAAGGAAATCATGGCACCCTGGGCGCAGACCGTGGTGACAGGACGAGCAAGGCTTGGGGG
  GATTCCCGTGGGAGTGATTGCTGTGGAGACACGGACTGTGGAGGTGGCAGTCCCTGCAGA
  CCCTGCCAACCTGGATTCTGAGGCCAAGATAATTCAGCAGGCAGGACAGGTGTGGTTCCC
  AGACTCAGCCTACAAAACCGCCCAGGCCATCAAGGACTTCAACCGGGAGAAGTTGCCCCT
  GATGATCTTTGCCAACTGGAGGGGGTTCTCCGGTGGCATGAAAGACATGTATGACCAGGT
  GCTGAAGTTTGGAGCCTACATCGTGGACGGCCTTAGACAATACAAACAGCCCATCCTGAT
  CTATATCCCGCCCTATGCGGAGCTCCGGGGAGGCTCCTGGGTGGTCATAGATGCCACCAT
  CAACCCGCTGTGCATAGAAATGTATGCAGACAAAGAGAGCAGGGGTGGTGTTCTGGAACC
  AGAGGGGACAGTGGAGATTAAGTTCCGAAAGAAAGATCTGATAAAGTCCATGAGAAGGAT
  CGATCCAGCTTACAAGAAGCTCATGGAACAGCTAGGGGAACCTGATCTCTCCGACAAGGA
  CCGAAAGGACCTGGAGGGCCGGCTAAAGGCTCGCGAGGACCTGCTGCTCCCCATCTACCA
  CCAGGTGGCGGTGCAGTTCGCCGACTTCCATGACACACCCGGCCGGATGCTGGAGAAGGG
  CGTCATATCTGACATCCTGGAGTGGAAGACCGCACGCACCTTCCTGTATTGGCGTCTGCG
  CCGCCTCCTCCTGGAGGACCAGGTCAAGCAGGAGATCCTGCAGGCCAGCGGGGAGCTGAG
  TCACGTGCATATCCAGTCCATGCTGCGTCGCTGGTTCGTGGAGACGGAGGGGGCTGTCAA
  GGCCTACTTGTGGGACAACAACCAGGTGGTTGTGCAGTGGCTGGAACAGCACTGGCAGGC
  AGGGGATGGCCCGCGCTCCACCATCCGTGAGAACATCACGTACCTGAAGCACGACTCTGT
  CCTCAAGACCATCCGAGGCCTGGTTGAAGAAAACCCCGAGGTGGCCGTGGACTGTGTGAT
  ATACCTGAGCCAGCACATCAGCCCAGCTGAGCGGGCGCAGGTCGTTCACCTGCTGTCTAC
  CATGGACAGCCCGGCCTCCACCTGACCGTGGCCCGCCCAGCCACTCCCGGGACCACGGCA
  AAAGGAACCACCCAGACCCACCACCCGTACACCCTCAGCAGACCCTGAAGACTTGCTTTT
  AAACAAAGAAAATCCTGGGCACTTCTGCAGGGCTGCTGGTTCCGAGCTGACACCCGTCTT
  AATAAAAGGCCCAGGAGTG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001093 unedited
  NAGTCAGATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCCCCAGTGA
  CGATTTTCTGAATGGTCTTGCTTCTTTGTCTATCTTGTCTGATTTTCTCCTGTCTGACCT
  TTTCCTGGTTAAAAATCTGGGGGAAAATGACGGACTCCAAGCCGATCACCAAGAGTAAAT
  CAGAAGCAAACCTCATCCCGAGCCAGGAGCCCTTTCCAGCCTCTGATAACTCAGGGGAGA
  CACCGCAGAGAAATGGGGAGGGCCACACTCTGCCCAAGACACCCAGCCAGGCCGAGCCAG
  CCTCCCACAAAGGCCCCAAAGATGCCGGTCGGCGGAGAAACTCCCTACCACCCTCCCACC
  AGAAGCCCCCAAGAAACCCCCTTTCTTCCAGTGACGCAGCACCCTCCCCAGAGCTTCAAG
  CCAACGGGACTGGGACACAAGGTCTGGAGGCCACAGATACCAATGGCCTGTCCTCCTCAG
  CCAGGCCCCAGGGCCAGCAAGCTGGCTCCCCCTCCAAAGAAGACAAGAAGCAGGCAAACA
  TCAAGAGGCAGCTGATGACCAACTTCATCCTGGGCTCTTTTGATGACTACTCCTCCGACG
  AGGACTCTGTTGCTGGCTCATCTCGTGAGTCTACCCGGAAGGGCAGCCGGGCCAGCTTGG
  GGGCCCTGTCCCTGGAGGCTTATCTGACCACAGGTGAAGCTGAGACCCGCGTCCCCACTA
  TGAGGCCGAGCATGTCGGGACTCCACCTGGTGAAGAGGGGACGGGAACACAAGAAGCTGG
  ACCTGCACAGAGACTTTACCGTGGCTTCTCCCGCTGAGTTTGTCACACGCTTTGGGGGGG
  GATCGGTCATCGAGAAGGTGCTTATTGCCACACACGGGATGCCGCTGTGAAGTGCATGCG
  CNTCATCCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001093 unedited
  NCCCACATCGGNNGATGGCACTTNCCAGGNNCCAGGNGAAAGNCACTGGGNGNAGGGGTC
  ACAGGGNATGCCACCCGGGNATCGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGAG
  TCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGGGGAAAAAGCCCCCCCGGGCCCTTTAAA
  AAAACGGGGGGGAACCCGGAACCCACACCCCCGGAAAAAGGCCCAAGAATTTCTTTGGTA
  AAAAACAAATCCTCAGGGGCCGCCGAGGGGGGACCGGGGGGGGGGCCGGGGGGGTCCCTT
  TGCCCGGGGCCCGGGGGGGGGGGGGGGGGCCCCGGGCAAGGGGGGGCCGGGCCGCCCCTG
  GGAAACAACAGGGGAAAAACCCGGGCCCCCCCAAATGGGCCGAAGGGCCGGCCCAAGGAA
  AAAAAAAAGGCCCCGGGCCCCCGGGGGGTTTCTTCAACCACGCCCCGGAAGGGCCTGAGG
  ACAAAAACCTGCCTCAAGGACCTGAAGGTCCCACGGGGGGGGGGGCGGGGGCCATCCCCG
  GGCTGGCAGGGGGGGTCCAACCACCGGACAACCCCCCGGTTGGTGGCCCACAAGTAGGGC
  TTGAAAGCCCCCTCCGTCTCCACAAAACAACGACCCAACATGGGACTGGGAATGCACGGG
  ACTCAACTCCCCGGTGGGCCGGAGGGACCCCCGGCTGGACCGGGCCTCCAGAAGGGGCGG
  CCCAAAACCCAATACGGGAAGGGGGGGGCGGGCCTCCCCTCCCGGAGGGCAGAAAAGGAG
  CCCCTTTTCAGAATCCCGCCGGGGGGGGTCATGAAAATTGGGAAACGGCCCCCCCCCTGG
  GGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_001093
• Insert Size: 7600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There is 2 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 2 aa.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001093.2, NP_001084.2
• RefSeq Size: 9251 bp
• RefSeq ORF: 7377 bp
• Locus ID: 32
• Cytogenetics: 12q24.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid biosynthesis, Insulin signaling pathway, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism
• Gene Summary: ' Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]'