CAIN (CABIN1) (NM_012295) Human Untagged Clone

CAT#: SC309877

CABIN1 (untagged)-Human calcineurin binding protein 1 (CABIN1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CABIN1
• Synonyms: CAIN; KB-318B8.7; PPP3IN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012295, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGTC
  ACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCA
  GAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAG
  GCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACTTATA
  AGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAGGCAGT
  GATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATC
  CCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACC
  TAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAA
  GGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCGGAAG
  GACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCAGCTGAGACAC
  AGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCC
  GGACCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATG
  TACAATCATCTCACCACCTGTGAGCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACC
  AGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGATCCAGCCAAGCACTGT
  CAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGCTTC
  CCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCA
  AGAAAGGGGTAAAACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGT
  CCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCC
  AGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCAGAAGCCA
  AACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGA
  AAAGCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGC
  TACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCG
  TCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGACTGCAGCAACAAGCA
  CATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGACCAAA
  GGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGCCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACT
  TCCCAGGGACCCACTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGA
  GGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGAC
  ATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCACCGCCATCCAGGTGG
  AGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCT
  GGAGGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTAT
  GAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGG
  CCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTGCTTCTTCTGCAGGACTCCTT
  GCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCAGCAG
  ATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCA
  TCGAGCAGGCCCTCTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGT
  GCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCC
  CACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGAAGACACCTTCCATT
  CTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATC
  CTCCCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGG
  GCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACC
  CTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTGCCTGTACAGCTTCCCCAGCAAGAA
  GAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTC
  ATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTG
  ACTTGGCCAACCTACTGAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGA
  CAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCC
  CCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTCCAAGG
  CCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCT
  GGCCCGGGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAG
  CATGCCACGCCCGTCTTGAACTGCTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGA
  TTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACGTCAATTGAAGCAGTGGAGAGGCGA
  GCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGT
  TTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCA
  AGGTGGCTGAGAAGCAGCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCT
  GCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCACTACCACAACCCACCTGAGCTGGCCATGGAGGCC
  CTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGTTGGTG
  CAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACAC
  ACCCAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTG
  CCGGGCCCCGGAGCCTCCCTCCCCTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTC
  CGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGACGACCGAAGCCAGGA
  CAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTG
  GAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTA
  AAGATCTTCAGGGGGCCACAGAAGAAAGAGGAAAAAACGAGGAGTCATTGGAGAGTACAGAAGGCTTCCG
  GGCTGCAGAGCAAGGTGTCCAGAAGCCTGCTGCAGAAACCCCAGCCTCTGCTTGCATCCCTGGCAAGCCC
  TCAGCATCCACACCCACCCTGTGGGATGGGAAGAAGAGAGGGGACCTCCCAGGGGAGCCAGTGGCCTTCC
  CCCAGGGGCTGCCGGCTGGTGCTGAGGAGCAGCGGCAGTTTCTCACAGAGCAGTGCATCGCCTCCTTCCG
  CCTGTGCCTGAGCCGCTTCCCCCAGCACTATAAGAGTCTCTACCGTCTGGCCTTCCTCTACACCTACAGC
  AAGACCCACCGGAACCTCCAGTGGGCCCGCGACGTGTTGCTAGGCAGCAGTATCCCGTGGCAACAACTGC
  AGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAGACCAATTTCTTCAACGGCATCTGGCGGAT
  CCCCGTGGACGAGATTGACCGGCCGGGCAGCTTTGCCTGGCACATGAACCGCTCCATCGTGCTGCTGCTC
  AAGGTGCTGGCCCAGCTGCGGGACCACAGCACCCTGCTGAAGGTGTCCTCCATGCTTCAGCGGACCCCAG
  ACCAGGGCAAGAAGTATCTGCGAGATGCTGACCGCCAGGTCCTGGCGCAGCGGGCCTTCATCCTCACTGT
  GAAGGTGCTCGAAGACACGCTGAGCGAGCTCGCAGAGGGGTCAGAACGCCCAGGGCCCAAGGTCTGTGGC
  CTCCCCGGAGCCAGGATGACCACCGATGTCTCACACAAGGCCAGTCCTGAGGATGGCCAGGAGGGCCTCC
  CCCAGCCGAAGAAGCCCCCTCTGGCTGATGGCTCAGGGCCAGGGCCCGAGCCAGGAGGCAAAGTGGGCCT
  CCTCAACCACCGGCCTGTGGCCATGGATGCAGGAGACAGTGCAGACCAAAGCGGGGAGCGGAAGGATAAA
  GAGAGCCCACGGGCAGGGCCCACTGAGCCCATGGACACGAGTGAGGCCACTGTTTGCCACTCAGACTTGG
  AGCGGACACCACCCCTGCTGCCAGGTCGCCCCGCAAGGGACCGGGGCCCCGAGAGCCGGCCCACTGAGCT
  GTCCCTGGAGGAGCTGAGCATCAGTGCCCGGCAGCAGCCCACCCCGCTCACCCCAGCCCAGCCAGCCCCC
  GCCCCCGCCCCCGCCACCACCACAGGGACCAGGGCAGGGGGCCACCCGGAGGAGCCGCTCTCCCGGCTCA
  GCCGCAAGAGGAAGCTCCTGGAGGACACAGAGTCAGGCAAGACACTTCTGTTGGATGCCTACCGTGTGTG
  GCAGCAGGGCCAGAAGGGTGTGGCCTATGACCTGGGCCGTGTGGAGAGGATCATGTCGGAGACCTACATG
  CTCATCAAGCAGGTGGATGAGGAGGCTGCGCTGGAGCAGGCTGTGAAGTTCTGCCAGGTCCATCTTGGGG
  CTGCCGCCCAGAGACAGGCCTCGGGGGACACCCCCACCACTCCAAAGCACCCCAAAGACAGCCGAGAGAA
  CTTCTTTCCTGTGACAGTGGTGCCCACAGCCCCTGACCCTGTGCCAGCTGACTCTGTCCAGCGGCCCAGT
  GATGCTCACACCAAGCCTCGCCCTGCACTAGCTGCCGCCACAACTATTATCACCTGCCCTCCGTCAGCAT
  CAGCTTCCACCCTGGACCAGTCCAAGGACCCTGGGCCTCCCCGGCCACACAGGCCTGAAGCTACCCCCAG
  CATGGCCTCTCTGGGCCCAGAGGGAGAAGAGCTGGCGAGAGTGGCAGAGGGCACCAGCTTCCCGCCTCAG
  GAGCCACGGCACAGTCCGCAGGTGAAGATGGCCCCCACAAGTTCCCCGGCAGAGCCACACTGCTGGCCGG
  CAGAGGCTGCCCTGGGCACAGGCGCTGAGCCCACCTGCAGCCAGGAGGGGAAACTGAGGCCTGAGCCGAG
  AAGGGATGGGGAGGCTCAGGAGGCTGCGAGTGAGACTCAGCCCCTGAGCTCTCCCCCAACAGCTGCCAGC
  TCCAAGGCCCCCAGCAGTGGGAGTGCCCAGCCACCAGAGGGTCACCCAGGCAAGCCTGAGCCCAGCCGGG
  CTAAGTCCCGCCCCCTGCCCAACATGCCAAAGCTGGTCATCCCCTCCGCCGCCACCAAGTTCCCCCCTGA
  GATCACCGTCACGCCACCCACCCCAACCCTGCTCTCCCCCAAAGGCAGCATCTCGGAGGAGACCAAGCAG
  AAGCTGAAGTCAGCCATCCTTTCTGCCCAGTCTGCTGCCAACGTGAGGAAGGAGAGCCTATGCCAGCCAG
  CCCTGGAGGTCCTGGAGACATCCAGCCAGGAGTCCTCGCTGGAGAGCGAGACAGACGAGGACGACGACTA
  CATGGACATTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_012295
• ORF Size: 6663 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012295.3, NP_036427.1
• RefSeq Size: 7222
• RefSeq ORF: 6663
• Locus ID: 23523
• Domains: TPR
• Protein Families: Druggable Genome
• Gene Summary: Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).