JARID2 (NM_004973) Human Untagged Clone

CAT#: SC309940

JARID2 (untagged)-Human jumonji, AT rich interactive domain 2 (JARID2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: JARID2
• Synonyms: JMJ
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004973, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCAAGGAAAGACCCAAGAGGAATATCATTCAGAAGAAATACGATGACAGTGATGGGATTCCGTGGT
  CAGAAGAACGGGTGGTACGTAAAGTCCTTTATTTGTCTCTGAAGGAGTTCAAGAATTCCCAGAAGAGGCA
  GCATGCGGAAGGCATTGCTGGGAGCCTGAAAACTGTGAATGGGCTCCTTGGTAATGACCAGTCTAAGGGA
  TTAGGACCAGCATCAGAACAGTCAGAGAATGAAAAGGACGATGCATCCCAAGTGTCCTCCACTAGCAACG
  ATGTTAGTTCTTCAGATTTTGAAGAAGGGCCGTCGAGGAAAAGGCCCAGGCTGCAAGCACAAAGGAAGTT
  TGCTCAGTCTCAGCCGAATAGTCCCAGCACAACTCCAGTAAAGATAGTGGAGCCATTGCTACCCCCTCCA
  GCTACTCAGATATCAGACCTCTCTAAAAGGAAGCCTAAGACAGAAGATTTTCTTACCTTTCTCTGCCTTC
  GAGGTTCTCCTGCGCTGCCCAACAGCATGGTGTATTTTGGAAGCTCTCAGGATGAGGAGGAAGTCGAGGA
  GGAAGATGATGAGACAGAAGACGTCAAAACAGCCACCAACAATGCTTCATCTTCATGCCAGTCGACCCCC
  AGGAAAGGAAAAACCCACAAACATGTTCACAACGGGCATGTTTTCAATGGTTCCAGCAGGTCAACACGGG
  AGAAGGAACCTGTTCAAAAACACAAAAGCAAAGAGGCCACTCCCGCAAAGGAGAAGCACAGCGATCACCG
  GGCTGACAGCCGCCGGGAGCAGGCTTCAGCTAACCACCCCGCAGCGGCCCCCTCCACGGGTTCCTCGGCC
  AAGGGGCTTGCTGCCACCCATCACCACCCCCCTCTGCATCGGTCGGCTCAGGACTTACGGAAACAGGTTT
  CTAAGGTAAACGGAGTCACTCGAATGTCATCTCTGGGTGCAGGTGTAACCAGTGCCAAAAAGATGCGCGA
  GGTCAGACCTTCACCATCCAAAACTGTGAAGTACACTGCCACGGTGACGAAGGGGGCTGTCACATACACC
  AAAGCCAAGAGAGAACTGGTCAAGGACACCAAACCCAATCACCACAAGCCCAGTTCCGCTGTCAACCACA
  CAATCTCAGGGAAAACTGAAAGTAGCAATGCAAAAACCCGCAAACAGGTGCTATCCCTCGGGGGGGCGTC
  CAAGTCCACTGGGCCCGCCGTCAATGGCCTCAAGGTCAGTGGCAGGTTGAACCCAAAGTCATGCACTAAG
  GAGGTGGGGGGGCGGCAGCTGCGGGAGGGCCTGCAGCTGCGGGAGGGGCTGCGGAACTCCAAGAGGAGAC
  TGGAAGAGGCACACCAGGCGGAGAAGCCGCAGTCGCCCCCCAAGAAGATGAAAGGGGCGGCTGGCCCCGC
  CGAAGGCCCTGGCAAGAAGGCCCCGGCCGAGAGAGGTCTGCTGAACGGACACGTGAAGAAGGAAGTGCCG
  GAGCGCAGTCTGGAGAGGAATCGGCCGAAGCGGGCCACGGCCGGGAAGAGCACGCCAGGCAGACAAGCAC
  ATGGCAAGGCGGACAGCGCCTCCTGTGAAAATCGTTCTACCTCGCAACCGGAGTCCGTGCACAAGCCGCA
  GGACTCGGGCAAGGCCGAGAAGGGCGGCGGCAAGGCCGGGTGGGCGGCCATGGACGAGATCCCCGTCCTC
  AGGCCCTCCGCCAAGGAGTTCCACGATCCGCTCATCTACATCGAGTCGGTCCGCGCTCAGGTGGAGAAGT
  TCGGGATGTGCAGGGTGATCCCCCCTCCGGACTGGCGGCCCGAGTGCAAGCTCAACGATGAGATGCGGTT
  TGTCACGCAGATTCAGCACATCCACAAGCTGGGCCGGCGCTGGGGCCCCAACGTGCAGCGGCTGGCCTGC
  ATCAAGAAGCACCTCAAATCTCAGGGCATCACCATGGACGAGCTCCCGCTCATAGGGGGCTGTGAGCTCG
  ACCTGGCCTGCTTTTTCCGGCTGATTAATGAGATGGGCGGCATGCAGCAAGTGACTGACCTCAAAAAATG
  GAACAAACTAGCAGACATGCTGCGCATCCCCAGAACTGCCCAGGACCGGCTGGCCAAGCTGCAGGAGGCC
  TACTGCCAGTACCTACTCTCCTACGACTCCCTGTCCCCAGAGGAGCACCGGCGGCTGGAGAAGGAGGTGC
  TGATGGAGAAGGAGATCCTGGAGAAGCGCAAGGGGCCGCTGGAAGGCCACACAGAGAACGACCACCACAA
  GTTCCACCCTCTGCCCCGCTTCGAGCCCAAGAATGGGCTCATCCACGGCGTGGCCCCCAGGAACGGCTTC
  CGCAGCAAGCTCAAGGAGGTGGGCCAGGCCCAGTTGAAGACTGGCCGGCGGCGACTCTTCGCTCAGGAAA
  AAGAAGTGGTCAAGGAAGAGGAGGAGGACAAAGGCGTCCTCAATGACTTCCACAAGTGCATCTATAAGGG
  AAGGTCTGTTTCTCTAACAACTTTTTATCGAACAGCGAGGAATATCATGAGCATGTGTTTCAGCAAGGAG
  CCTGCCCCAGCCGAAATCGAGCAAGAGTACTGGAGGCTAGTGGAAGAGAAGGACTGCCACGTGGCAGTGC
  ACTGCGGCAAGGTGGACACCAACACTCACGGCAGTGGATTCCCAGTAGGAAAATCAGAACCCTTTTCGAG
  GCATGGATGGAACCTCACCGTCCTCCCCAATAACACAGGGTCCATCCTGCGTCACCTCGGTGCTGTGCCT
  GGAGTGACTATTCCCTGGCTAAATATTGGCATGGTCTTTTCTACCTCATGCTGGTCTCGAGACCAAAATC
  ACCTTCCATACATTGACTACTTACACACTGGTGCTGACTGCATTTGGTATTGCATTCCTGCTGAGGAGGA
  GAACAAGCTGGAAGATGTGGTCCACACCCTGCTGCAAGCCAATGGCACCCCAGGGCTGCAGATGCTGGAA
  AGCAACGTCATGATCTCCCCGGAGGTGCTGTGCAAAGAGGGGATCAAGGTGCACAGGACCGTGCAGCAGA
  GTGGCCAGTTTGTCGTCTGCTTCCCGGGATCCTTTGTGTCCAAAGTGTGCTGTGGGTACAGCGTGTCTGA
  AACCGTGCACTTTGCTACCACCCAGTGGACAAGTATGGGCTTTGAGACCGCCAAGGAAATGAAGCGTCGC
  CATATAGCTAAGCCATTCTCCATGGAGAAGTTACTCTACCAGATTGCACAAGCAGAAGCAAAAAAAGAAA
  ACGGTCCCACTCTCAGTACCATCTCAGCCCTCCTGGATGAGCTCAGGGATACAGAGCTGCGGCAGCGCAG
  GCAGCTGTTCGAGGCTGGCCTCCACTCCTCCGCACGCTATGGCAGCCACGATGGCAGCAGCACGGTGGCG
  GACGGGAAGAAAAAGCCTCGAAAGTGGCTGCAGTTGGAGACGTCAGAGAGGAGGTGTCAGATCTGCCAGC
  ACCTGTGCTACCTGTCCATGGTGGTACAAGAGAACGAAAACGTCGTGTTCTGTCTGGAGTGTGCTCTGCG
  CCACGTGGAGAAACAGAAGTCCTGCCGAGGGCTGAAGTTGATGTACCGCTACGATGAGGAACAGATTATC
  AGTCTGGTCAATCAGATCTGCGGCAAAGTGTCTGGTAAAAACGGCAGCATTGAGAACTGTCTCAGTAAAC
  CCACACCAAAAAGAGGTCCCCGCAAGAGAGCGACAGTGGACGTGCCCCCCTCCCGTCTGTCAGCCTCCAG
  TTCATCCAAAAGTGCTTCGAGCTCATCATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_004973
• ORF Size: 3741 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004973.3, NP_004964.2
• RefSeq Size: 6112
• RefSeq ORF: 3741
• Locus ID: 3720
• Domains: ARID, JmjC, JmjN, zf-C5HC2
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.