ADAMTS18 (NM_199355) Human Untagged Clone

CAT#: SC309941

ADAMTS18 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAMTS18
• Synonyms: ADAMTS21; KNO2; MMCAT
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_199355, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGTGCGCCCTCCTGCTCGCGTGTGCCTTCCCGGCTGCGGGTTCGGGCCCGCCGAGGGGCCTGGCGG
  GACTGGGGCGCGTGGCCAAGGCGCTCCAGCTGTGCTGCCTCTGCTGTGCGTCGGTCGCCGCGGCCTTAGC
  CAGTGACAGCAGCAGCGGCGCCAGCGGATTAAATGATGATTACGTCTTTGTCACGCCAGTAGAAGTAGAC
  TCAGCCGGGTCATATATTTCACACGACATTTTGCACAACGGCAGGAAAAAGCGATCGGCGCAGAATGCCA
  GAAGCTCCCTGCACTACCGATTTTCAGCATTTGGACAGGAACTGCACTTAGAACTTAAGCCCTCGGCGAT
  TTTGAGCAGTCACTTTATTGTCCAGGTACTTGGAAAAGATGGTGCTTCAGAGACTCAGAAACCCGAGGTG
  CAGCAATGCTTCTATCAGGGATTTATCAGAAATGACAGCTCCTCCTCTGTCGCTGTGTCTACGTGTGCTG
  GCTTGTCAGGTTTAATAAGGACACGAAAAAATGAATTCCTCATCTCGCCATTACCTCAGCTTCTGGCCCA
  GGAACACAACTACAGCTCCCCTGCGGGTCACCATCCTCACGTACTGTACAAAAGGACAGCAGAGGAGAAG
  ATCCAGCGGTACCGTGGCTACCCCGGCTCTGGCCGGAATTATCCTGGTTACTCCCCAAGTCACATTCCCC
  ATGCATCTCAGAGTCGAGAGACAGAGTATCACCATCGAAGGTTGCAAAAGCAGCATTTTTGTGGACGACG
  CAAGAAATATGCTCCCAAGCCTCCCACAGAGGACACCTATCTAAGGTTTGATGAATATGGGAGCTCTGGG
  CGACCCAGAAGATCAGCTGGAAAATCACAAAAGGGCCTCAATGTGGAAACCCTCGTGGTGGCAGACAAGA
  AAATGGTGGAAAAGCATGGCAAGGGAAATGTCACCACATACATTCTCACAGTAATGAACATGGTTTCTGG
  CCTATTTAAAGATGGGACTATTGGAAGTGACATAAACGTGGTTGTGGTGAGCCTAATTCTTCTGGAACAA
  GAACCTGGAGGATTATTGATCAACCATCATGCAGACCAGTCTCTGAATAGTTTTTGTCAATGGCAGTCTG
  CCCTCATTGGAAAGAATGGCAAGAGACATGATCATGCCATCTTACTAACAGGATTTGATATTTGTTCTTG
  GAAGAATGAACCATGTGACACTCTAGGGTTTGCCCCCATCAGTGGAATGTGCTCTAAGTACCGAAGTTGT
  ACCATCAATGAGGACACAGGACTTGGCCTTGCCTTCACCATCGCTCATGAGTCAGGGCACAACTTTGGTA
  TGATTCACGACGGAGAAGGGAATCCCTGCAGAAAGGCTGAAGGCAATATCATGTCTCCCACACTGACCGG
  AAACAATGGAGTGTTTTCATGGTCTTCCTGCAGCCGCCAGTATCTCAAGAAATTCCTCAGCACACCTCAG
  GCGGGGTGTCTAGTGGATGAGCCCAAGCAAGCAGGACAGTATAAATATCCGGACAAACTACCAGGACAGA
  TTTATGATGCTGACACACAGTGTAAATGGCAATTTGGAGCAAAAGCCAAGTTATGCAGCCTTGGTTTTGT
  GAAGGATATTTGCAAATCACTTTGGTGCCACCGAGTAGGCCACAGGTGTGAGACCAAGTTTATGCCCGCA
  GCAGAAGGGACCGTTTGTGGCTTGAGTATGTGGTGTCGGCAAGGCCAGTGCGTAAAGTTTGGGGAGCTCG
  GGCCCCGGCCCATCCACGGCCAGTGGTCCGCCTGGTCGAAGTGGTCAGAATGTTCCCGGACATGTGGTGG
  AGGAGTCAAGTTCCAGGAGAGACACTGCAATAACCCCAAGCCTCAGTATGGTGGCTTATTCTGTCCAGGT
  TCTAGCCGTATTTATCAGCTGTGCAATATTAACCCTTGCAATGAAAATAGCTTGGATTTTCGGGCTCAAC
  AGTGTGCAGAATATAACAGCAAACCTTTCCGTGGATGGTTCTACCAGTGGAAACCCTATACAAAAGTGGA
  AGAGGAAGATCGATGCAAACTGTACTGCAAGGCTGAGAACTTTGAATTTTTTTTTGCAATGTCCGGCAAA
  GTGAAAGATGGAACTCCCTGCTCCCCAAACAAAAATGATGTTTGTATTGACGGGGTTTGTGAACTAGTGG
  GATGTGATCATGAACTAGGCTCTAAAGCAGTTTCAGATGCTTGTGGCGTTTGCAAAGGTGATAATTCAAC
  TTGCAAGTTTTATAAAGGCCTGTACCTCAACCAGCATAAAGCAAATGAATATTATCCGGTGGTCCTCATT
  CCAGCTGGCGCCCGAAGCATCGAAATCCAGGAGCTGCAGGTTTCCTCCAGTTACCTCGCAGTTCGAAGCC
  TCAGTCAAAAGTATTACCTCACCGGGGGCTGGAGCATCGACTGGCCTGGGGAGTTCCCCTTCGCTGGGAC
  CACGTTTGAATACCAGCGCTCTTTCAACCGCCCGGAACGTCTGTACGCGCCAGGGCCCACAAATGAGACG
  CTGGTCTTTGAAATTCTGATGCAAGGCAAAAATCCAGGGATAGCTTGGAAGTATGCACTTCCCAAGGTCA
  TGAATGGAACTCCACCAGCCACAAAAAGACCTGCCTATACCTGGAGTATCGTGCAGTCAGAGTGCTCCGT
  CTCCTGTGGTGGAGGTTACATAAATGTAAAGGCCATTTGCTTGCGAGATCAAAATACTCAAGTCAATTCC
  TCATTCTGCAGTGCAAAAACCAAGCCAGTAACTGAGCCCAAAATCTGCAACGCTTTCTCCTGCCCGGCTT
  ACTGGATGCCAGGTGAATGGAGTACATGCAGCAAGGCCTGTGCTGGAGGCCAGCAGAGCCGAAAGATCCA
  GTGTGTGCAAAAGAAGCCCTTCCAAAAGGAGGAAGCAGTGTTGCATTCTCTCTGTCCAGTGAGCACACCC
  ACTCAGGTCCAAGCCTGCAACAGCCATGCCTGCCCTCCACAATGGAGCCTTGGACCCTGGTCTCAGTGTT
  CCAAGACCTGTGGACGAGGGGTGAGGAAGCGTGAACTCCTCTGCAAGGGCTCTGCCGCAGAAACCCTCCC
  CGAGAGCCAGTGTACCAGTCTCCCCAGACCTGAGCTGCAGGAGGGCTGTGTGCTTGGACGATGCCCCAAG
  AACAGCCGGCTACAGTGGGTCGCTTCTTCGTGGAGCGAGTGTTCTGCAACCTGTGGTTTGGGTGTGAGGA
  AGAGGGAGATGAAGTGCAGCGAGAAGGGCTTCCAGGGAAAGCTGATAACTTTCCCAGAGCGAAGATGCCG
  TAATATTAAGAAACCAAATCTGGACTTGGAAGAGACCTGCAACCGACGGGCTTGCCCAGCCCATCCAGTG
  TACAACATGGTAGCTGGATGGTATTCATTGCCGTGGCAGCAGTGCACAGTCACCTGTGGGGGAGGGGTCC
  AGACCCGGTCAGTCCACTGTGTTCAGCAAGGCCGGCCTTCCTCAAGTTGTCTGCTCCATCAGAAACCTCC
  GGTGCTACGAGCCTGTAATACAAACTTCTGTCCAGCTCCTGAAAAGAGAGAGGATCCATCCTGCGTAGAT
  TTCTTCAACTGGTGTCACCTAGTTCCTCAGCATGGTGTCTGCAACCACAAGTTTTACGGAAAACAATGCT
  GCAAGTCATGCACAAGGAAGATCTGA
  
  
• Restriction Sites: Please inquire
• ACCN: NM_199355
• ORF Size: 3666 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_199355.1, NP_955387.1
• RefSeq Size: 5510
• RefSeq ORF: 3666
• Locus ID: 170692
• Protein Families: Protease, Secreted Protein
• Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016]
  Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1).