Symplekin (SYMPK) (NM_004819) Human Untagged Clone

CAT#: SC309970

SYMPK (untagged)-Human symplekin (SYMPK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYMPK
• Synonyms: SPK; SYM
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004819 edited
  CGGCGGCGGCGGCGGCGGAGTGTAGGAAGAGGCACTGCTGAGGGGGCGCGAGGGGAACGG
  AGGCCAGAGCTGCGCTGACAGCAGCCATGGCGAGCGGCAGTGGAGACAGCGTCACCCGTC
  GGAGCGTGGCATCACAGTTTTTCACTCAAGAGGAGGGGCCGGGCATCGATGGCATGACCA
  CCTCAGAGAGGGTGGTGGATCTTCTGAACCAGGCGGCGCTGATCACCAATGACTCAAAGA
  TCACAGTGCTCAAACAGGTCCAGGAGCTGATCATCAACAAAGACCCCACACTACTGGACA
  ACTTCCTGGATGAGATCATCGCATTCCAAGCAGACAAGTCAATCGAAGTGCGAAAATTTG
  TCATCGGCTTCATCGAGGAGGCATGCAAGCGAGACATTGAGTTGCTGCTGAAACTCATTG
  CAAACCTCAACATGCTCTTGAGGGACGAGAATGTGAACGTGGTGAAGAAGGCTATCCTCA
  CCATGACCCAGCTCTACAAGGTGGCCCTGCAGTGGATGGTAAAGTCACGGGTCATTAGCG
  AGCTACAGGAGGCCTGCTGGGACATGGTATCTGCCATGGCGGGGGACATCATCCTGCTAT
  TGGACTCTGACAATGACGGCATCCGCACCCACGCCATCAAGTTTGTGGAGGGCCTCATTG
  TCACCCTGTCACCCCGCATGGCTGACTCAGAGATACCCCGACGCCAGGAGCATGATATCA
  GCCTGGACCGCATCCCTCGTGACCACCCCTACATCCAGTACAACGTGCTATGGGAAGAGG
  GCAAGGCAGCCTTGGAGCAGCTGCTTAAGTTCATGGTGCACCCTGCCATCTCCTCCATCA
  ACCTGACCACAGCGCTGGGCTCCCTTGCCAATATCGCCCGCCAGAGACCCATGTTCATGT
  CTGAGGTGATCCAGGCCTATGAAACTCTGCATGCCAACCTGCCCCCGACGCTGGCCAAAT
  CGCAGGTGAGCAGTGTGCGTAAGAATCTGAAGCTGCACCTGTTGAGTGTGCTGAAGCACC
  CGGCTTCCTTGGAGTTCCAGGCCCAGATCACCACCCTGCTGGTGGACCTGGGCACACCTC
  AGGCCGAGATCGCCCGCAACATGCCGAGCAGCAAGGACACCCGCAAGCGGCCCCGCGATG
  ACTCGGACTCCACACTCAAGAAGATGAAGCTGGAGCCCAACCTGGGGGAGGACGATGAGG
  ACAAAGACTTGGAGCCAGGCCCGTCGGGGACCTCGAAGGCCTCAGCGCAGATCTCCGGCC
  AGTCAGACACGGACATCACAGCTGAGTTCCTGCAGCCTCTGCTGACGCCTGATAATGTGG
  CTAATCTGGTCCTCATCAGCATGGTGTACCTACCCGAGGCCATGCCAGCCTCCTTCCAGG
  CCATCTACACCCCCGTGGAGTCAGCAGGCACGGAAGCCCAGATCAAGCACCTGGCTCGGC
  TCATGGCCACACAGATGACAGCTGCCGGACTGGGACCAGGTGTAGAGCAGACCAAACAGT
  GCAAGGAGGAGCCCAAGGAGGAGAAGGTGGTGAAGACAGAGAGCGTCCTGATCAAGCGGC
  GCCTGTCAGCCCAGGGCCAAGCCATCTCGGTGGTGGGTTCCCTGAGCTCCATGTCCCCCC
  TGGAGGAAGAGGCACCGCAGGCCAAGAGGAGGCCAGAGCCCATTATCCCTGTCACTCAGC
  CCCGGCTGGCAGGCGCTGGTGGGCGCAAGAAAATTTTCCGTCTCAGCGACGTGCTGAAGC
  CCCTTACCGATGCCCAGGTGGAAGCCATGAAGCTGGGCGCTGTGAAGCGGATCCTGCGGG
  CTGAGAAGGCTGTGGCCTGCAGCGGGGCAGCCCAGGTCCGCATAAAGATCCTGGCCAGCC
  TGGTGACACAGTTCAACTCGGGCCTGAAGGCGGAGGTCCTGTCCTTCATCCTGGAGGATG
  TGCGGGCCCGCCTGGACCTGGCCTTCGCCTGGCTCTACCAGGAGTACAACGCCTACCTGG
  CCGCAGGTGCCTCGGGCTCCCTGGACAAGTATGAGGACTGCCTCATCCGCCTGTTGTCTG
  GCCTGCAGGAGAAACCAGACCAGAAGGATGGGATCTTCACCAAGGTTGTGCTGGAGGCGC
  CACTCATCACAGAGAGTGCCCTGGAGGTGGTCCGCAAGTACTGCGAGGATGAGAGTCGCA
  CCTATCTGGGCATGTCCACACTTCGAGACCTGATCTTCAAGCGCCCGTCCCGCCAGTTCC
  AGTACTTGCATGTCCTCCTCGACCTCAGCTCCCATGAGAAGGACAAGGTGCGCTCCCAGG
  CCCTGCTGTTCATCAAACGCATGTATGAGAAGGAGCAGCTGCGGGAGTATGTGGAGAAAT
  TTGCCCTCAACTACCTGCAGCTCCTGGTGCACCCCAACCCACCGTCTGTGCTGTTTGGAG
  CTGACAAGGACACAGAGGTGGCAGCACCCTGGACGGAGGAGACAGTGAAGCAGTGTCTGT
  ACCTCTACCTGGCCCTCCTGCCTCAGAACCACAAGCTGATCCACGAACTGGCGGCCGTGT
  ACACTGAAGCCATCGCCGACATCAAGCGGACGGTGCTGAGGGTCATTGAGCAGCCGATCC
  GAGGAATGGGCATGAACTCCCCGGAGCTGCTCCTGCTGGTGGAAAATTGTCCCAAGGGAG
  CAGAGACACTGGTCACAAGATGTCTGCACAGCCTCACAGACAAAGTCCCACCCTCCCCAG
  AGCTGGTGAAGCGGGTCCGGGATCTCTACCACAAGCGACTGCCAGACGTCCGCTTCCTCA
  TCCCGGTGCTCAATGGGCTGGAGAAGAAAGAGGTGATCCAGGCCCTGCCTAAACTCATCA
  AACTCAACCCCATCGTGGTGAAGGAAGTCTTCAACCGCCTGCTGGGCACCCAGCATGGTG
  AGGGAAACTCAGCCTTGTCCCCGCTGAACCCTGGAGAGCTCCTGATCGCATTACACAACA
  TTGACTCCGTGAAGTGCGACATGAAATCCATCATCAAAGCCACCAACCTGTGCTTTGCGG
  AGCGGAACGTGTACACGTCAGAGGTGCTGGCCGTGGTGATGCAGCAGCTGATGGAGCAGA
  GCCCCCTGCCCATGCTGCTCATGAGGACCGTCATCCAGTCCCTGACCATGTACCCCCGCC
  TGGGGGGCTTCGTCATGAACATCCTGTCCCGCCTCATCATGAAGCAGGTGTGGAAGTACC
  CCAAGGTGTGGGAGGGCTTCATCAAGTGCTGCCAGCGCACAAAGCCCCAGAGCTTCCAGG
  TCATCCTGCAGCTGCCGCCCCAGCAGCTGGGAGCCGTCTTTGACAAGTGCCCAGAGCTCC
  GGGAGCCCCTGCTGGCCCATGTCCGCTCCTTCACCCCCCACCAGCAAGCTCACATCCCTA
  ACTCCATCATGACCATCTTGGAGGCCAGCGGCAAGCAGGAGCCAGAGGCCAAGGAGGCGC
  CTGCGGGGCCCTTGGAGGAGGATGATCTGGAGCCCCTGACCTTGGCGCCGGCCCCAGCAC
  CCCGGCCCCCTCAGGACCTCATCGGCCTGCGACTGGCCCAGGAGAAGGCCTTAAAGCGGC
  AGCTGGAGGAGGAACAGAAGCTGAAGCCGGGAGGAGTGGGAGCCCCCTCCTCTTCCTCCC
  CCTCTCCCTCTCCGTCGGCCCGGCCAGGCCCGCCCCCGTCTGAGGAAGCCATGGATTTCC
  GGGAGGAGGGGCCTGAGTGCGAGACCCCGGGCATCTTCATCAGCATGGATGACGACTCGG
  GGCTGACCGAGGCCGCGCTGTTGGACTCTAGTCTCGAGGGCCCCCTACCCAAGGAGACGG
  CAGCGGGCGGGCTGACCTTGAAGGAGGAGCGGAGCCCCCAGACCCTCGCACCTGTTGGAG
  AAGATGCTATGAAGACTCCCAGCCCGGCTGCCGAGGACGCCAGGGAACCCGAGGCCAAGG
  GGAACAGCTGACGGGGCTCGAGGGGGAAAGGGGGTGGGACAGGGACTCGGGGCTGGGGGA
  CGGGGCGGGGCTTGACCTGCGGGTGCTTTGCCTTAAAAAGAAATAAAAGATGTGAACTTG
  GGCAAGTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004819
• ORF Size: 3429 bp
• Insert Size: 4100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_004819.1.

Reference Data

• RefSeq: NM_004819.1, NP_004810.1
• RefSeq Size: 3984
• RefSeq ORF: 3429
• Locus ID: 8189
• Protein Pathways: Tight junction
• Gene Summary: This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]