SLC4A4 (NM_003759) Human Untagged Clone

CAT#: SC309999

SLC4A4 (untagged)-Human solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC4A4
• Synonyms: hhNMC; HNBC1; KNBC; kNBC1; NBC1; NBC2; NBCe1-A; pNBC; SLC4A5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003759, the custom clone sequence may differ by one or more nucleotides
  ATGTCCACTGAAAATGTGGAAGGGAAGCCCAGTAACCTTGGGGAGAGAGGAAGAGCCCGG
  AGCTCCACTTTCCTCAGGGTTGTCCAGCCAATGTTTAACCACAGTATTTTCACTTCTGCA
  GTCTCTCCTGCTGCAGAACGCATCCGATTCATCTTGGGAGAGGAGGATGACAGCCCAGCT
  CCCCCTCAGCTCTTCACGGAACTGGATGAGCTGCTGGCCGTGGATGGGCAGGAGATGGAG
  TGGAAGGAAACAGCCAGGTGGATCAAGTTTGAAGAAAAAGTGGAACAGGGTGGGGAAAGA
  TGGAGCAAGCCCCATGTGGCCACATTGTCCCTTCATAGTTTATTTGAGCTGAGGACATGT
  ATGGAGAAAGGATCCATCATGCTTGATCGGGAGGCTTCTTCTCTCCCACAGTTGGTGGAG
  ATGATTGTTGACCATCAGATTGAGACAGGCCTATTGAAACCTGAACTTAAGGATAAGGTG
  ACCTATACTTTGCTCCGGAAGCACCGGCATCAAACCAAGAAATCCAACCTTCGGTCCCTG
  GCTGACATTGGGAAGACAGTCTCCAGTGCAAGTAGGATGTTTACCAACCCTGATAATGGT
  AGCCCAGCCATGACCCATAGGAATCTGACTTCCTCCAGTCTGAATGACATTTCTGATAAA
  CCGGAGAAGGACCAGCTGAAGAATAAGTTCATGAAAAAATTGCCACGTGATGCAGAAGCT
  TCCAACGTGCTTGTTGGGGAGGTTGACTTTTTGGATACTCCTTTCATTGCCTTTGTTAGG
  CTACAGCAGGCTGTCATGCTGGGTGCCCTGACTGAAGTTCCTGTGCCCACAAGGTTCTTG
  TTCATTCTCTTAGGTCCTAAGGGGAAAGCCAAGTCCTACCACGAGATTGGCAGAGCCATT
  GCCACCCTGATGTCTGATGAGGTGTTCCATGACATTGCTTATAAAGCAAAAGACAGGCAC
  GACCTGATTGCTGGTATTGATGAGTTCCTAGATGAAGTCATCGTCCTTCCACCTGGGGAA
  TGGGATCCAGCAATTAGGATAGAGCCTCCTAAGAGTCTTCCATCCTCTGACAAAAGAAAG
  AATATGTACTCAGGTGGAGAGAATGTTCAGATGAATGGGGATACGCCCCATGATGGAGGT
  CACGGAGGAGGAGGACATGGGGATTGTGAAGAATTGCAGCGAACTGGACGGTTCTGTGGT
  GGACTAATTAAAGACATAAAGAGGAAAGCGCCATTTTTTGCCAGTGATTTTTATGATGCT
  TTAAATATTCAAGCTCTTTCGGCAATTCTCTTCATTTATCTGGCAACTGTAACTAATGCT
  ATCACTTTTGGAGGACTGCTTGGGGATGCCACTGACAACATGCAGGGCGTGTTGGAGAGT
  TTCCTGGGCACTGCTGTCTCTGGAGCCATCTTTTGCCTTTTTGCTGGTCAACCACTCACT
  ATTCTGAGCAGCACCGGACCTGTCCTAGTTTTTGAGAGGCTTCTATTTAATTTCAGCAAG
  GACAATAATTTTGACTATTTGGAGTTTCGCCTTTGGATTGGCCTGTGGTCCGCCTTCCTA
  TGTCTCATTTTGGTAGCCACTGATGCCAGCTTCTTGGTTCAATACTTCACACGTTTCACG
  GAGGAGGGCTTTTCCTCTCTGATTAGCTTCATCTTTATCTATGATGCTTTCAAGAAGATG
  ATCAAGCTTGCAGATTACTACCCCATCAACTCCAACTTCAAAGTGGGCTACAACACTCTC
  TTTTCCTGTACCTGTGTGCCACCTGACCCAGCTAATATCTCAATATCTAATGACACCACA
  CTGGCCCCAGAGTATTTGCCAACTATGTCTTCTACTGACATGTACCATAATACTACCTTT
  GACTGGGCATTTTTGTCGAAGAAGGAGTGTTCAAAATACGGAGGAAACCTCGTCGGGAAC
  AACTGTAATTTTGTTCCTGATATCACACTCATGTCTTTTATCCTCTTCTTGGGAACCTAC
  ACCTCTTCCATGGCTCTGAAAAAATTCAAAACTAGTCCTTATTTTCCAACCACAGCAAGA
  AAACTGATCAGTGATTTTGCCATTATCTTGTCCATTCTCATCTTTTGTGTAATAGATGCC
  CTAGTAGGCGTGGACACCCCAAAACTAATTGTGCCAAGTGAGTTCAAGCCAACAAGTCCA
  AACCGAGGTTGGTTCGTTCCACCGTTTGGAGAAAACCCCTGGTGGGTGTGCCTTGCTGCT
  GCTATCCCGGCTTTGTTGGTCACTATACTGATTTTCATGGACCAACAAATTACAGCTGTG
  ATTGTAAACAGGAAAGAACATAAACTCAAGAAAGGAGCAGGGTATCACTTGGATCTCTTT
  TGGGTGGCCATCCTCATGGTTATATGCTCCCTCATGGCTCTTCCGTGGTATGTAGCTGCT
  ACGGTCATCTCCATTGCTCACATCGACAGTTTGAAGATGGAGACAGAGACTTCTGCACCT
  GGAGAACAACCAAAGTTTCTAGGAGTGAGGGAACAAAGAGTCACTGGAACCCTTGTGTTT
  ATTCTGACTGGTCTGTCAGTCTTTATGGCTCCCATCTTGAAGTTTATACCCATGCCTGTA
  CTCTATGGTGTGTTCCTGTATATGGGAGTAGCATCCCTTAATGGTGTGCAGTTCATGGAT
  CGTCTGAAGCTGCTTCTGATGCCTCTGAAGCATCAGCCTGACTTCATCTACCTGCGTCAT
  GTTCCTCTGCGCAGAGTCCACCTGTTCACTTTCCTGCAGGTGTTGTGTCTGGCCCTGCTT
  TGGATCCTCAAGTCAACGGTGGCTGCTATCATTTTTCCAGTAATGATCTTGGCACTTGTA
  GCTGTCAGAAAAGGCATGGACTACCTCTTCTCCCAGCATGACCTCAGCTTCCTGGATGAT
  GTCATTCCAGAAAAGGACAAGAAAAAGAAGGAGGATGAGAAGAAAAAGAAAAAGAAGAAG
  GGAAGTCTGGACAGTGACAATGATGATTCTGACTGCCCATACTCAGAAAAAGTTCCAAGT
  ATTAAAATTCCAATGGACATCATGGAACAGCAACCTTTCCTAAGCGATAGCAAACCTTCT
  GACAGAGAAAGATCACCAACATTCCTTGAACGCCACACATCATGCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_003759
• ORF Size: 3108 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003759.1, NP_003750.1
• RefSeq Size: 7586
• RefSeq ORF: 3108
• Locus ID: 8671
• Domains: HCO3_cotransp
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (2) with a shorter and distinct N-terminus compared to isoform 1.