WWP2 (NM_007014) Human Untagged Clone

CAT#: SC310067

WWP2 (untagged)-Human WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WWP2
• Synonyms: AIP2; WWp2-like
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007014 edited
  CGGTGATGATATGGCATCTGCCAGCTCTAGCCGGGCAGGAGTGGCCCTGCCTTTTGAGAA
  GTCTCAGCTCACTTTGAAAGTGGTGTCCGCAAAGCCCAAGGTGCATAATCGTCAACCTCG
  AATTAACTCCTACGTGGAGGTGGCGGTGGATGGACTCCCCAGTGAGACCAAGAAGACTGG
  GAAGCGCATTGGGAGCTCTGAGCTTCTCTGGAATGAGATCATCATTTTGAATGTCACGGC
  ACAGAGTCATTTAGATTTAAAGGTCTGGAGCTGCCATACCTTGAGAAATGAACTGCTAGG
  CACCGCATCTGTCAACCTCTCCAACGTCTTGAAGAACAATGGGGGCAAAATGGAGAACAT
  GCAGCTGACCCTGAACCTGCAGACGGAGAACAAAGGCAGCGTTGTCTCAGGCGGAGAGCT
  GACAATTTTCCTGGACGGGCCAACTGTTGATCTGGGAAATGTGCCTAATGGCAGTGCCCT
  GACAGATGGATCACAGCTGCCTTCGAGAGACTCCAGTGGAACAGCAGTAGCTCCAGAGAA
  CCGGCACCAGCCCCCCAGCACAAACTGCTTTGGTGGAAGATCCCGGACGCACAGACATTC
  GGGTGCTTCAGCCAGAACAACCCCAGCAACCGGCGAGCAAAGCCCCGGTGCTCGGAGCCG
  GCACCGCCAGCCCGTCAAGAACTCAGGCCACAGTGGCTTGGCCAATGGCACAGTGAATGA
  TGAACCCACAACAGCCACTGATCCCGAAGAACCTTCCGTTGTTGGTGTGACGTCCCCACC
  TGCTGCACCCTTGAGTGTGACCCCGAATCCCAACACGACTTCTCTCCCTGCCCCAGCCAC
  ACCGGCTGAAGGAGAGGAACCCAGCACTTCGGGTACACAGCAGCTCCCAGCGGCTGCCCA
  GGCCCCCGACGCTCTGCCTGCTGGATGGGAACAGCGAGAGCTGCCCAACGGACGTGTCTA
  TTATGTTGACCACAATACCAAGACCACCACCTGGGAGCGGCCCCTTCCTCCAGGCTGGGA
  AAAACGCACAGATCCCCGAGGCAGGTTTTACTATGTGGATCACAATACTCGGACCACCAC
  CTGGCAGCGTCCGACCGCGGAGTACGTGCGCAACTATGAGCAGTGGCAGTCGCAGCGGAA
  TCAGCTCCAGGGGGCCATGCAGCACTTCAGCCAAAGATTCCTCTACCAGTCTTCGAGTGC
  TTCGACTGACCATGATCCCCTGGGCCCCCTCCCTCCTGGCTGGGAGAAAAGACAGGACAA
  TGGACGGGTGTATTACGTGAACCATAACACTCGCACGACCCAGTGGGAGGATCCCCGGAC
  CCAGGGGATGATCCAGGAACCAGCTCTGCCCCCAGGATGGGAGATGAAATACACCAGCGA
  GGGGGTGCGATACTTTGTGGACCACAATACCCGCACCACCACCTTTAAGGATCCTCGCCC
  GGGGTTTGAGTCGGGGACGAAGCAAGGTTCCCCTGGTGCTTATGACCGCAGTTTTCGGTG
  GAAGTATCACCAGTTCCGTTTCCTCTGCCATTCAAATGCCCTACCTAGCCACGTGAAGAT
  CAGCGTTTCCAGGCAGACGCTTTTCGAAGATTCCTTCCAACAGATCATGAACATGAAACC
  CTATGACCTGCGCCGCCGGCTCTACATCATCATGCGTGGCGAGGAGGGCCTGGACTATGG
  GGGCATCGCCAGAGAGTGGTTTTTCCTCCTGTCTCAYGAGGTGCTCAACCCTATGTATTG
  TTTATTTGAATATGCCGGAAAGAACAATTACTGCCTGCAGATCAACCCCGCCTCCTCCAT
  CAACCCGGACCACCTCACCTACTTTCGCTTTATAGGCAGATTCATCGCCATGGCGCTGTA
  CCATGGAAAGTTCATCGACACGGGCTTCACCCTCCCTTTCTACAAGCGGATGCTCAATAA
  GAGACCAACCCTGAAAGACCTGGAGTCCATTGACCCTGAGTTCTACAACTCCATTGTCTG
  GATCAAAGAGAACAACCTGGAAGAATGTGGCCTGGAGCTGTACTTCATCCAGGACATGGA
  GATACTGGGCAAGGTGACGACCCACGAGCTGAAGGAGGGCGGCGAGAGCATCCGGGTCAC
  GGAGGAGAACAAGGAAGAGTACATCATGCTGCTGACTGACTGGCGTTTCACCCGAGGCGT
  GGAAGAGCAGACCAAAGCCTTCCTGGATGGCTTCAACGAGGTGGCCCCGCTGGAGTGGCT
  GCGCTACTTTGACGAGAAAGAGCTGGAGCTGATGCTGTGCGGCATGCAGGAGATAGACAT
  GAGCGACTGGCAGAAGAGCACCATCTACCGGCACTACACCAAGAACAGCAAGCAGATCCA
  GTGGTTCTGGCAGGTGGTGAAGGAGATGGACAACGAGAAGAGGATCCGGCTGCTGCAGTT
  TGTCACCGGTACCTGCCGCCTGCCCGTCGGGGGATTTGCCGAACTCATCGGTAGCAACGG
  ACCACAGAAGTTTTGCATTGACAAAGTTGGCAAGGAAACCTGGCTGCCCAGAAGCCACAC
  CTGCTTCAACCGTCTGGATCTTCCACCCTACAAGAGCTACGAACAGCTGAGAGAGAAGCT
  GCTGTATGCCATTGAGGAGACCGAGGGCTTTGGACAGGAGTAACCGAGGCCGCCCCTCCC
  ACGCCCCCCAGCGCACATGTAGTCCTGAGTCCTCCCTGCCTGAGAGGCCACTGGCCCCGC
  AGCCCTTGGGAGGCCCCCGTGGATGTGGCCCTGTGTGGGACCACACTGTCATCTCGCTGC
  TGGCAGAAAAGCCTGATCCCAGGAGGCCCTGCAGTTCCCCCGACCCGCGGATGGCAGTCT
  GGAATAAAGCCCCCTAGTTGCCTTTGGCCCCACCTTTGCAAAGTTCCAGAGGGCTGACCC
  TCTCTGCAAAACTCTCCCCTGTCCTCTAGACCCCACCCTGGGTGTATGTGAGTGTGCAAG
  GGAAGGTGTTGCATCCCCAGGGGCTGCCGCAGAGGCCGGAGACCTCCTGGACTAGTTCGG
  CGAGGAGACTGGCCACTGGGGGTGGCTGTTCGGGACTGAGAGCGCCAAGGGTCTTTGCCA
  GCAAAGGAGGTTCTGCCTGTAATTGAGCCTCTCTGATGATGGAGATGAAGTGAAGGTCTG
  AGGGAGCGGGCCCTGGGGCGAGGCCATCTCTGCCTGCCTCCCTAGCAGGCGCCAGCGGTG
  GAGGCTGAGTCGCAGGACACATGCCGGCCAGTTAATTCATTCTCAGCMAATGAAGGTTTG
  TCTAAGCTGCCTGGGTATCCACGGGACAAAAACAGCAAACTCCCTCAGACTTTGTCCATG
  TATAAACTTGAAGTGGTTGTGTTGTAGGGTTGCAGGTTTTTTGTTACGCTGCTGTCACTT
  TCTGTCCAGGAGCTGGCACCCCAGGTGTTCTGAGACCTTGAGGGACCCAGACCTTTGGGT
  CCAAGAGTTTCCCAAACAGCCACGCCTCTCAGGAACCCACCTGGCGGTTCCGTGAGCTCA
  GGCAGGCCTGACCCGGCGGCACAGCCTGGCAGGGACCTCGTCCCCAAGCCTGGCAGAATG
  AGAGGGGTTGAGGTCCCGAGCGCCACTCCTAGCCTTGCCGCCTTCAATAGAGAAGAAATC
  CCTTTGCTAGATAGGGTCCCCCAGGCAGTCCCCAGTGGCGGGACACAGGGGTCCGGCTGT
  GGAGCTCCCCTGCCAGCCCCTGGAGCTCCAGGAGGGCCTGTTGGTCCCCTGTTCAGAATG
  GAGTGCAGCCCGCCAGCGGAAAGTGTTCATTCTGCATAGGTGTGAGGCTTTATCTGCACA
  CAGGACATGAAAACCAGCAGAAAGGCCCTGAGCTGCTGCATAGCCCCATCTGATTTCTGC
  AGTTCCCGCCAGCCTCCAACACGGGGACTCTGCCGTAACTGGAATCTTCATAGGTCATAT
  TGAAATCTTCAAGGTGACCATGCCCCACCGGGGTGCTGGGGCAGTAGTCATGGCAGACTC
  CCGGCCTGGGCCCCCAGGATTCTAGGACCCCCAGGCAGCCCCTTGGACTGGTCCCGGGTG
  CCTTCCAAGCACAGTCTCCATGCTCCCAGATTCTCGACCTTCCCCCGGCCCGGGAGGTGC
  AGCCTGCGTCTGCCTCTGTCGTGTGTGCTGATTTGAGTGGCTTAGCTTGCCACAGCGCAA
  CCTCTTCTGTCCCTTTCAGTCATTTGCTGTACTTCCCTGTGGCACGTTACCATGGAAGCC
  GCTCCAGGGTGGGTCAGGGTGCAAGCTGCTGGTGAGGTTTGGAAGCATCAGGCTCACGGG
  TGTTCATGTGTGTTCGTGCGTGTGTGTGCGTACGTGTATATAACTGAAGTGTCTGTACGG
  AATGCCCTTTGCTAGCCATGGGCTGGTCACCAGATTGTTTTGTAATGCCCGCCCCTTGCC
  TCGATATTGCCAGTTTCTTGTGCAATAAACTATCAGCAGCTGAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_007014
• ORF Size: 2613 bp
• Insert Size: 4400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_007014.3, NP_008945.2
• RefSeq Size: 4527
• RefSeq ORF: 2613
• Locus ID: 11060
• Domains: C2, HECT, WW
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (WWP2-FL). Variants 1 and 5 encode the same isoform.